TY - JOUR AU - Nemes, Attila AU - Kormányos, Árpád AU - Orosz, Andrea AU - Ambrus, Nóra AU - Várkonyi, Tamás AU - Lengyel, Csaba Attila TI - Autonomic function and specific right atrial functions - Is there a relationship? Correlations from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study JF - JOURNAL OF CLINICAL ULTRASOUND J2 - J CLIN ULTRASOUND PY - 2024 PG - 8 SN - 0091-2751 DO - 10.1002/jcu.23672 UR - https://m2.mtmt.hu/api/publication/34778284 ID - 34778284 N1 - Department of Medicine, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary Department of Pharmacology and Pharmacotherapy, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary Export Date: 23 April 2024 CODEN: JCULD Correspondence Address: Nemes, A.; Department of Medicine, H-6725 Szeged, emmelweis street 8, P.O. Box 427, Hungary; email: nemes.attila@med.u-szeged.hu AB - Similarly to the ventricles, the atria are under sympathetic/parasympathetic neural regulation. Accordingly, correlations were investigated between Ewing's standard cardiovascular reflex tests (SCRTs) and three-dimensional speckle-tracking echocardiography (3DSTE)-derived right atrial (RA) volumes and strains in healthy subjects.The study comprised 45 healthy adults, but 5 subjects were excluded due to inferior image quality for 3DSTE-derived RA assessments. The remaining 40 individuals being in sinus rhythm had a mean age of 35.1 ± 3.5 years (20 men). Two-dimensional, Doppler, 3DSTE and SCRTs were performed in all cases.RA maximum volume and total and passive RA stroke volumes correlated with the Valsalva ratio. Active RA stroke volume and emptying fraction showed correlations with 30/15 ratio. Peak global and mean segmental RA circumferential (CS) and longitudinal strains (LS) showed correlation with the Valsalva ratio. At atrial contraction, global RA-LS and mean segmental RA-CS showed correlations with the Valsalva ratio. Moreover, mean segmental RA-CS correlated with 30/15 ratio and mean segmental RA radial strain showed correlations with systolic blood pressure in response to standing. Autonomic neuropathy score correlated with peak global RA-LS.Autonomic function parameters have significant associations with specific RA functions in healthy adults, making the latter possible indicators of autonomic dysregulation. LA - English DB - MTMT ER - TY - JOUR AU - Nemes, Attila AU - Kormányos, Árpád AU - Ruzsa, Zoltán AU - Achim, Alexandru AU - Ambrus, Nóra AU - Lengyel, Csaba Attila TI - Right Ventricular Longitudinal Shortening is not Associated with Left Ventricular Rotational Mechanics in Healthy Adults - Insights from the Three-dimensional Speckle-tracking Echocardiographic MAGYAR-Healthy Study JF - REVIEWS IN CARDIOVASCULAR MEDICINE J2 - REV CARDIOVASC MED VL - 25 PY - 2024 IS - 2 PG - 9 SN - 1530-6550 DO - 10.31083/j.rcm2502053 UR - https://m2.mtmt.hu/api/publication/34557988 ID - 34557988 N1 - Export Date: 23 April 2024 CODEN: RCMEC Correspondence Address: Nemes, A.; Department of Medicine, Hungary; email: nemes.attila@med.u-szeged.hu LA - English DB - MTMT ER - TY - JOUR AU - Nemes, Attila AU - Kormányos, Árpád AU - Orosz, Andrea AU - Ambrus, Nóra AU - Várkonyi, Tamás AU - Lengyel, Csaba Attila TI - Correlations between vegetative autonomic function and specific left atrial functions in healthy adults: Insights from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study JF - JOURNAL OF CLINICAL ULTRASOUND J2 - J CLIN ULTRASOUND VL - 52 PY - 2024 IS - 2 SP - 178 EP - 185 PG - 8 SN - 0091-2751 DO - 10.1002/jcu.23603 UR - https://m2.mtmt.hu/api/publication/34400260 ID - 34400260 N1 - Department of Medicine, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary Department of Pharmacology and Pharmacotherapy, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary Cited By :2 Export Date: 23 April 2024 CODEN: JCULD Correspondence Address: Nemes, A.; Department of Medicine, Semmelweis Street 8, P.O. Box 427, Hungary; email: nemes.attila@med.u-szeged.hu AB - The functioning of the left atrium (LA) is partly controlled by the neural system. It was purposed to evaluate correlations between the result of Ewing's 5 standard cardiovascular reflex tests (SCRTs) characterizing autonomic function and LA volumetric and functional features as assessed by three-dimensional speckle-tracking echocardiography (3DSTE) in healthy individuals.The current study comprised 18 healthy volunteers being in sinus rhythm (mean age: 35 ± 12 years, 10 men). Measurement of blood pressure, ECG, 5 SCRTs, two-dimensional Doppler echocardiography and 3DSTE were performed. These parameters were in normal ranges in all cases.From LA volumetric parameters, only systolic total atrial emptying fraction (r = 0.559, p = 0.037) and early diastolic passive atrial emptying fraction (r = 0.539, p = 0.047) correlated with systolic blood pressure response to standing representing sympathetic autonomic function. From LA strains, peak mean segmental LA radial strain (RS) (r = -0.532, p = 0.050), global and mean segmental LA circumferential strain (CS) (r = 0.662, p = 0.010 and r = 0.635, p = 0.015, respectively) representing systolic LA function correlated with Valsalva ratio representing parasympathetic autonomic function. Global LA-RS (r = -0.713, p = 0.040) and LA-CS (r = 0.657, p = 0.011) and mean segmental LA-CS (r = 0.723, p = 0.003) at atrial contraction representing end-diastolic atrial contraction showed correlations with Valsalva ratio, as well. Peak global and mean segmental LA-CS (r = 0.532, p = 0.050 and r = 0.530, p = 0.050) and the same strains at atrial contraction (r = 0.704, p = 0.005 and r = 0.690, p = 0.006) representing systolic function and end-diastolic atrial contraction correlated with systolic blood pressure response to standing representing both parasympathetic and sympathetic autonomic functions.Significant correlations between features of vegetative autonomic function represented by Ewing's 5 SCRTs and specific LA functions represented by 3DSTE-derived LA volume-based functional properties and strains could be demonstrated in healthy adults. LA - English DB - MTMT ER - TY - JOUR AU - Christofi, A AU - Kormányos, Árpád AU - Kalapos, Anita AU - Domsik, Péter AU - Gyenes, Nándor AU - Ambrus, Nóra AU - Gavallér, Edit Henriette AU - Csajbók, Éva AU - Julesz, János AU - Forster, Tamás AU - Csanády, Miklós AU - Horváth, Á AU - Lengyel, Csaba Attila AU - Nemes, Attila AU - Valkusz, Zsuzsanna TI - A NÖVEKEDÉSI HORMON HATÁSA A SZÍV FIZIOLÓGIÁJÁRA JF - MAGYAR BELORVOSI ARCHIVUM J2 - MBA VL - 76 PY - 2023 IS - 5-6 SP - 303 EP - 303 PG - 1 SN - 0133-5464 UR - https://m2.mtmt.hu/api/publication/34559525 ID - 34559525 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Nemes, Attila AU - Kormányos, Árpád AU - Ambrus, Nóra AU - Lengyel, Csaba Attila TI - Complex Relationship of Left Ventricular Rotational Mechanics and Deformation Represented by Strain Parameters in Healthy Adults—Detailed Analysis from the Three-Dimensional Speckle-Tracking Echocardiographic MAGYAR-Healthy Study JF - JOURNAL OF CLINICAL MEDICINE J2 - J CLIN MED VL - 12 PY - 2023 IS - 23 PG - 9 SN - 2077-0383 DO - 10.3390/jcm12237389 UR - https://m2.mtmt.hu/api/publication/34408305 ID - 34408305 N1 - Export Date: 23 April 2024 Correspondence Address: Nemes, A.; Department of Medicine, Hungary; email: nemes.attila@med.u-szeged.hu Tradenames: Artida, Toshiba Medical Systems, Japan; PST-25SX; PST-30BT; SPSS version 22, SPSS, United States; Ultra Extend, Toshiba Medical Systems, Japan Manufacturers: SPSS; Toshiba Medical Systems, Japan; SPSS, United States; Toshiba Medical Systems AB - Introduction: Left ventricular (LV) strains are measures of deformation that reflect LV function quantifying the rate of LV contraction, providing information in three directions in space: radial (RS), longitudinal (LS) and circumferential directions (CS). The LV moves around its longitudinal axis in a special movement called LV rotational mechanics. The present study aimed to assess associations between three-dimensional speckle-tracking echocardiography (3DSTE)-derived LV rotational mechanics and LV strains in healthy adult subjects. Methods: The present study consisted of 174 healthy adults (mean age: 32.8 ± 12.2 years, 79 males). Complete two-dimensional Doppler echocardiography and 3DSTE were performed in all subjects. Results: While LV-gRS and LV-gLS did not show associations with increased basal LV rotation, the lowest LV-gCS was seen in the presence of the highest LV basal rotation. An increase in basal LV rotation and consequential LV twist were not associated with apical LV rotation. While LV-gLS was not associated with the increase in apical LV rotation, LV-gRS and LV-gCS showed a trend towards increasing values. An increase in LV-gRS was associated with an increasing trend towards apical LV rotation, LV twist and LV-gCS and the preservation of basal LV rotation. LV-gLS also increased but only up to a certain value. An increase in LV-gCS was associated with a tendency towards a decrease in basal LV rotation and a tendency towards an increase in LV-gRS and LV-gLS. The highest LV-gCS was associated with the highest apical LV rotation and LV twist. The highest apical LV rotation, LV twist and LV-gCS were seen in the presence of the highest LV-gLS, while basal LV rotation and LV-gRS were not associated with increasing LV-gLS. Conclusions: Basal LV rotation has been shown to have an inverse relationship with LV-gCS, but without being related to LV-gRS and LV-gLS, while apical LV rotation is associated with LV strains in all directions, but to a different extent, suggesting a complex relationship between LV rotational mechanics and LV strains in healthy adults. LA - English DB - MTMT ER - TY - JOUR AU - Nemes, Attila AU - Kormányos, Árpád AU - Ambrus, Nóra AU - Lengyel, Csaba Attila TI - Similarities and Differences between Three-Dimensional Speckle-Tracking Echocardiography-Derived Left and Right Atrial Volumes and Volume-Based Functional Properties in the Same Healthy Adults—A Detailed Analysis from the MAGYAR-Healthy Study JF - MEDICINA-LITHUANIA J2 - MED LITH VL - 59 PY - 2023 IS - 12 PG - 12 SN - 1010-660X DO - 10.3390/medicina59122051 UR - https://m2.mtmt.hu/api/publication/34400254 ID - 34400254 N1 - Export Date: 23 April 2024 Correspondence Address: Nemes, A.; Department of Medicine, Hungary; email: nemes.attila@med.u-szeged.hu AB - Background and Objectives: It would be important to know what happens to the volume and volume-based functional properties of one atrium if the size of the other atrium is larger or smaller than the average. Therefore, the present study aimed to perform three-dimensional speckle-tracking echocardiography (3DSTE)-derived quantification of left atrial (LA) and right atrial (RA) volumes and volume-based functional properties to examine these associations in healthy adults with mean and lower or higher than mean atrial volumes. Materials and Methods: The present study consisted of 179 healthy volunteers with a mean age of 32.3 ± 12.3 years (92 males). Three-dimensional speckle-tracking echocardiography-derived LA and RA volumes and volume-based functional properties were determined in all cases. Results: When different LA or RA volume groups were evaluated, both LA and RA showed the same pattern of volume changes in all phases of atrial function with higher LA or RA volumes. In case of low and mean LA volumes, RA volumes were higher compared to their LA counterpart. In case of mean and high RA volumes, RA volumes proved to be higher as well. In case of mean LA or RA volumes, differences between LA and RA stroke volumes (SVs) could not be detected, but all atrial emptying fractions (EFs) were lower for RA than for LA. Some differences were detected in counterpart LA/RA total, passive, and active atrial SVs and EFs values in the presence of lower/higher than mean LA/RA volume. Conclusions: In case of mean LA or RA volumes, RA volumes are higher compared to their LA counterpart, LA-SVs and RA-SVs are similar, but atrial EFs are lower for RA than for LA. If lower/higher than mean LA or RA volumes are present, some differences in patterns of changes in counterpart atrial volumes—SVs and EFs—could be detected. LA - English DB - MTMT ER - TY - JOUR AU - Nemes, Attila AU - Kormányos, Árpád AU - Ambrus, Nóra AU - Lengyel, Csaba Attila AU - Valkusz, Zsuzsanna TI - Myocardial, Valvular, and Vascular Structural and Functional Properties in Acromegaly JF - JOURNAL OF CLINICAL MEDICINE J2 - J CLIN MED VL - 12 PY - 2023 IS - 21 PG - 16 SN - 2077-0383 DO - 10.3390/jcm12216857 UR - https://m2.mtmt.hu/api/publication/34227610 ID - 34227610 N1 - Összes idézések száma a WoS-ban: 0 AB - Acromegaly is an uncommon systematic endocrine disease caused by the hypersecretion of human growth hormone and, consequently, of insulin-like growth factor-1 during adulthood. Acromegaly could cause a typical cardiomyopathy characterized by left ventricular hypertrophy associated with diastolic dysfunction, which later could progress to systolic dysfunction. Moreover, some valvular and vascular abnormalities are also associated with acromegaly. This present review aims to summarize available information regarding acromegaly-associated abnormalities in myocardial, valvular, and vascular structural and functional properties and their relationship to disease activity and treatment options. LA - English DB - MTMT ER - TY - JOUR AU - Nemes, Attila AU - Kormányos, Árpád AU - Ruzsa, Zoltán AU - Achim, Alexandru AU - Ambrus, Nóra AU - Lengyel, Csaba Attila TI - Left ventricular rotational mechanics and left ventricular volumes: is there a relationship in healthy adults?—three-dimensional speckle-tracking echocardiography-derived insights from the MAGYAR-Healthy Study JF - QUANTITATIVE IMAGING IN MEDICINE AND SURGERY J2 - QUANT IMAG MED SURG (QUIMS) VL - 13 PY - 2023 IS - 10 SP - 6583 EP - 6589 PG - 7 SN - 2223-4292 DO - 10.21037/qims-23-178 UR - https://m2.mtmt.hu/api/publication/34189509 ID - 34189509 N1 - Cited By :1 Export Date: 23 April 2024 Correspondence Address: Nemes, A.; Department of Medicine, Semmelweis Street 8, Hungary; email: nemes.attila@med.u-szeged.hu LA - English DB - MTMT ER - TY - JOUR AU - Nemes, Attila AU - Kormányos, Árpád AU - Ambrus, Nóra AU - Szolnoky, Győző AU - Kemény, Lajos TI - Left ventricular deformation in patients with lymphedema before and after the use of medical compression stockings—detailed analysis from the three-dimensional speckle-tracking echocardiographic MAGYAR-Path Study JF - QUANTITATIVE IMAGING IN MEDICINE AND SURGERY J2 - QUANT IMAG MED SURG (QUIMS) VL - 13 PY - 2023 IS - 10 SP - 6590 EP - 6597 PG - 8 SN - 2223-4292 DO - 10.21037/qims-23-243 UR - https://m2.mtmt.hu/api/publication/34189504 ID - 34189504 N1 - Department of Medicine, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary Department of Dermatology and Allergology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary Export Date: 23 April 2024 Correspondence Address: Nemes, A.; Department of Medicine, Semmelweis street 8, Hungary; email: nemes.attila@med.u-szeged.hu Tradenames: Artida, Toshiba, Japan Manufacturers: Toshiba, Japan LA - English DB - MTMT ER - TY - JOUR AU - Nemes, Attila AU - Kormányos, Árpád AU - Rácz, Gergely AU - Ruzsa, Zoltán AU - Achim, Alexandru AU - Ambrus, Nóra AU - Lengyel, Csaba Attila TI - Tricuspid annular and right atrial volume changes are associated in healthy adults—insights from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study JF - FRONTIERS IN CARDIOVASCULAR MEDICINE J2 - FRONT CARDIOVASC MED VL - 10 PY - 2023 PG - 9 SN - 2297-055X DO - 10.3389/fcvm.2023.1140599 UR - https://m2.mtmt.hu/api/publication/34134022 ID - 34134022 N1 - Export Date: 12 October 2023 Correspondence Address: Nemes, A.; Department of Medicine, Hungary; email: nemes.attila@med.u-szeged.hu Tradenames: Artida, Toshiba Medical Systems, Japan; Ultra Extend, Toshiba Medical Systems, Japan Manufacturers: Toshiba Medical Systems, Japan LA - English DB - MTMT ER -