@article{MTMT:31365295,
	title = {Steroidal ferrocenes as potential enzyme inhibitors of the estrogen biosynthesis},
	url = {https://m2.mtmt.hu/api/publication/31365295},
	author = {Herman, Bianka Edina and Gardi, János and Julesz, János and Tömböly, Csaba and Szánti-Pintér, Eszter and Fehér, Klaudia and Skodáné Földes, Rita and Szécsi, Mihály},
	doi = {10.1007/s42977-020-00023-7},
	journal-iso = {BIOL FUTURA},
	journal = {BIOLOGIA FUTURA},
	volume = {71},
	unique-id = {31365295},
	issn = {2676-8615},
	year = {2020},
	eissn = {2676-8607},
	pages = {249-264},
	orcid-numbers = {Szánti-Pintér, Eszter/0000-0001-8263-9884; Skodáné Földes, Rita/0000-0002-9810-1509; Szécsi, Mihály/0000-0002-4272-1362}
}

@article{MTMT:30446615,
	title = {New Metabolic Influencer on Oxytocin Release: The Ghrelin},
	url = {https://m2.mtmt.hu/api/publication/30446615},
	author = {Szabó, Renáta and Ménesi, Rudolf and Molnár, Andor and Szalai, Zita and Daruka, Lejla and Tóth, Gábor and Gardi, János and Gálfi, Márta and Börzsei, Denise and Kupai, Krisztina and Juhász, Anna and Radács, Marianna and László, Ferenc and Varga, Csaba and Pósa, Anikó},
	doi = {10.3390/molecules24040735},
	journal-iso = {MOLECULES},
	journal = {MOLECULES},
	volume = {24},
	unique-id = {30446615},
	issn = {1420-3049},
	year = {2019},
	eissn = {1420-3049},
	orcid-numbers = {Molnár, Andor/0000-0001-5980-2276; Szalai, Zita/0000-0002-8722-0211; Gálfi, Márta/0000-0002-7143-133X; Kupai, Krisztina/0000-0002-0644-1718; Radács, Marianna/0000-0003-0381-9276; Varga, Csaba/0000-0002-2678-665X; Pósa, Anikó/0000-0003-2167-2888}
}

@article{MTMT:30445256,
	title = {Enhanced In Vitro Antitumor Activity of GnRH-III-Daunorubicin Bioconjugates Influenced by Sequence Modification},
	url = {https://m2.mtmt.hu/api/publication/30445256},
	author = {Schuster, Sabine and Biri-Kovács, Beáta and Szeder, Bálint and Buday, László and Gardi, János and Szabó, Zsuzsanna and Halmos, Gábor and Mező, Gábor},
	doi = {10.3390/pharmaceutics10040223},
	journal-iso = {PHARMACEUTICS},
	journal = {PHARMACEUTICS},
	volume = {10},
	unique-id = {30445256},
	issn = {1999-4923},
	abstract = {Receptors for gonadotropin releasing hormone (GnRH) are highly expressed in various human cancers including breast, ovarian, endometrial, prostate and colorectal cancer. Ligands like human GnRH-I or the sea lamprey analogue GnRH-III represent a promising approach for the development of efficient drug delivery systems for targeted tumor therapy. Here, we report on the synthesis and cytostatic effect of 14 oxime bond-linked daunorubicin GnRH-III conjugates containing a variety of unnatural amino acids within the peptide sequence. All compounds demonstrated a reduced cell viability in vitro on estrogen receptor α (ERα) positive and ERα negative cancer cells. The best candidate revealed an increased cancer cell growth inhibitory effect compared to our lead-compound GnRH-III-[⁴Lys(Bu),⁸Lys(Dau=Aoa)]. Flow cytometry and fluorescence microscopy studies showed that the cellular uptake of the novel conjugate is substantially improved leading to an accelerated delivery of the drug to its site of action. However, the release of the active drug-metabolite by lysosomal enzymes was not negatively affected by amino acid substitution, while the compound provided a high stability in human blood plasma. Receptor binding studies were carried out to ensure a high binding affinity of the new compound for the GnRH-receptor. It was demonstrated that GnRH-III-[²ΔHis,³d-Tic,⁴Lys(Bu),⁸Lys(Dau=Aoa)] is a highly potent and promising anticancer drug delivery system for targeted tumor therapy.},
	keywords = {DAUNORUBICIN; drug delivery system; CELLULAR UPTAKE; Antitumor activity; Targeted cancer therapy; oxime linkage; Gonadotropin releasing hormone III; Peptide drug conjugates},
	year = {2018},
	eissn = {1999-4923},
	orcid-numbers = {Schuster, Sabine/0000-0001-9888-4446; Biri-Kovács, Beáta/0000-0001-5803-9969; Buday, László/0000-0003-3518-5757; Mező, Gábor/0000-0002-7618-7954}
}

@article{MTMT:3184963,
	title = {Is there a role of iNOS activation in the delayed antiarrhythmic effect of sodium nitrite?},
	url = {https://m2.mtmt.hu/api/publication/3184963},
	author = {Demeter-Haludka, Vivien and Juhász, László and Kovács, Mária and Gardi, János and Végh, Ágnes},
	doi = {10.1139/cjpp-2016-0357},
	journal-iso = {CAN J PHYSIOL PHARM},
	journal = {CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY},
	volume = {95},
	unique-id = {3184963},
	issn = {0008-4212},
	abstract = {This study aimed to examine whether inducible nitric oxide synthase (iNOS) plays a role in the delayed antiarrhythmic effect of sodium nitrite. Twenty-one dogs were infused intravenously with sodium nitrite (0.2 micromol/kg/min) for 20 min, either in the absence (<i>n</i>=12) or in the presence of the iNOS inhibitor S-(2-aminoethyl)-isothiourea (AEST; total dose: 2.0 mg/kg;<i> i.v.</i>, <i>n</i>=9). Control dogs (<i>n</i>=12) were given saline. Twenty-four hours later, all the dogs were subjected to a 25 min period occlusion of the left anterior descending (LAD) coronary artery, followed by rapid reperfusion. Dogs treated with AEST and nitrite were received again AEST prior to the occlusion. Compared to the controls, sodium nitrite markedly reduced the number of ectopic beats, the number and incidence of ventricular tachycardia and the incidence of ventricular fibrillation during occlusion and increased survival (0% vs. 50%) from the combined ischaemia and reperfusion insult. Although AEST completely inhibited iNOS activity, the nitrite induced increased NO bioavailability during occlusion was not substantially modified. Furthermore, AEST attenuated but did not completely abolish the antiarrhythmic effect of nitrite. The marked delayed antiarrhythmic effect of sodium nitrite is not entirely due to the activation of iNOS; other mechanisms may certainly play a role.},
	year = {2017},
	eissn = {1205-7541},
	pages = {447-454},
	orcid-numbers = {Juhász, László/0000-0001-5477-9572}
}

@article{MTMT:3130700,
	title = {Ghrelin-Induced Enhancement of Vasopressin and Oxytocin Secretion in Rat Neurohypophyseal Cell Cultures},
	url = {https://m2.mtmt.hu/api/publication/3130700},
	author = {Gálfi, Márta and Radács, Marianna and Molnár, Zsolt and Budai, I and Tóth, Gábor and Pósa, Anikó and Kupai, Krisztina and Szalai, Zita and Szabó, Renáta and Molnár, Andor and Gardi, János and Laszlo, FA and Varga, Csaba},
	doi = {10.1007/s12031-016-0850-4},
	journal-iso = {J MOL NEUROSCI},
	journal = {JOURNAL OF MOLECULAR NEUROSCIENCE},
	volume = {60},
	unique-id = {3130700},
	issn = {0895-8696},
	abstract = {The effects of ghrelin on vasopressin and oxytocin secretion 
		were studied in 13-14-day cell cultures of isolated rat 
		neurohypophyseal tissue. The vasopressin and oxytocin 
		contents of the supernatant were determined by 
		radioimmunoassay after a 1- or 2-h incubation. Significantly 
		increased levels of vasopressin and oxytocin production were 
		detected in the cell culture media following ghrelin 
		administration, depending on the ghrelin doses. The oxytocin 
		level proved to be more elevated than that of vasopressin. 
		The increase of vasopressin and oxytocin secretion could be 
		totally blocked by previous administration of the ghrelin 
		receptor antagonist ([D-Lys3]-growth hormone-releasing 
		peptide-6). Application of the ghrelin receptor antagonist 
		after ghrelin administration proved ineffective. The results 
		indicate that vasopressin and oxytocin release is influenced 
		directly by the ghrelin system, and the effects of ghrelin on 
		vasopressin and oxytocin secretion from the neurohypophyseal 
		tissue in rats can occur at the level of the posterior 
		pituitary. Our observations lend support to the view that 
		neurohypophysis contains ghrelin receptors.},
	year = {2016},
	eissn = {1559-1166},
	pages = {525-530},
	orcid-numbers = {Gálfi, Márta/0000-0002-7143-133X; Radács, Marianna/0000-0003-0381-9276; Molnár, Zsolt/0000-0001-5176-149X; Tóth, Gábor/0000-0002-3604-4385; Pósa, Anikó/0000-0003-2167-2888; Kupai, Krisztina/0000-0002-0644-1718; Szalai, Zita/0000-0002-8722-0211; Molnár, Andor/0000-0001-5980-2276; Varga, Csaba/0000-0002-2678-665X}
}

@CONFERENCE{MTMT:3081947,
	title = {A 17β-HSD1 enzimaktivitás in vitro vizsgálata 13α-ösztron származékokkal. A Magyar Endokrinológiai és Anyagcsere Társaság XXVI. Jubileumi Kongresszusa},
	url = {https://m2.mtmt.hu/api/publication/3081947},
	author = {Herman, Bianka Edina and Szabó, Johanna and Bacsa, Ildikó and Wölfling, János and Schneider, Gyula and Mernyák, Erzsébet and Szécsi, Mihály and Gardi, János and Valkusz, Zsuzsanna},
	booktitle = {A Magyar Endokrinológiai és Anyagcsere Társaság XXVI. Jubileumi Kongresszusa},
	unique-id = {3081947},
	year = {2016},
	pages = {159-159},
	orcid-numbers = {Bacsa, Ildikó/0000-0001-8277-631X; Wölfling, János/0000-0002-3037-309X; Mernyák, Erzsébet/0000-0003-4494-1817; Szécsi, Mihály/0000-0002-4272-1362; Valkusz, Zsuzsanna/0000-0003-1928-6160}
}

@article{MTMT:3072269,
	title = {Screening and follow up of an extended Hungarian family with familial medullary thyroid cancer},
	url = {https://m2.mtmt.hu/api/publication/3072269},
	author = {Valkusz, Zsuzsanna and Sepp, Krisztián and Gardi, János and Patócs, Attila Balázs},
	doi = {10.1530/endoabs.41.EP1109},
	journal-iso = {ENDOCR ABSTR},
	journal = {ENDOCRINE ABSTRACTS},
	volume = {41},
	unique-id = {3072269},
	issn = {1470-3947},
	year = {2016},
	eissn = {1479-6848},
	orcid-numbers = {Valkusz, Zsuzsanna/0000-0003-1928-6160; Sepp, Krisztián/0000-0001-9400-5213; Patócs, Attila Balázs/0000-0001-7506-674X}
}

@misc{MTMT:3072268,
	title = {Screening and follow up of an extended Hungarian family with familial medullary thyroid cancer},
	url = {https://m2.mtmt.hu/api/publication/3072268},
	author = {Valkusz, Zsuzsanna and Sepp, Krisztián and Gardi, János and Patócs, Attila Balázs},
	unique-id = {3072268},
	year = {2016},
	orcid-numbers = {Valkusz, Zsuzsanna/0000-0003-1928-6160; Sepp, Krisztián/0000-0001-9400-5213; Patócs, Attila Balázs/0000-0001-7506-674X}
}

@{MTMT:3023632,
	title = {A 17α-hidroxiláz-C17,20-liáz (P45017α) enzim aktivitásának gátlása N-oxi 17-pikolinilidén szteroid származékokkal},
	url = {https://m2.mtmt.hu/api/publication/3023632},
	author = {Szabó, N and Ajdukovic, JJ and Sakac, MN and Durendic, EA and Jovanovic-Santa, SS and Penov, Gasi KM and Gardi, János and Pajor, L and Julesz, János and Szécsi, Mihály},
	booktitle = {Innováció a Természettudományban – Doktorandusz konferencia},
	unique-id = {3023632},
	year = {2015},
	pages = {41-41},
	orcid-numbers = {Szécsi, Mihály/0000-0002-4272-1362}
}

@article{MTMT:2902081,
	title = {A növekedésihormon-felszabadító hormon (GHRH) receptorok potenciális szerepe radioaktív szívkárosodás esetén},
	url = {https://m2.mtmt.hu/api/publication/2902081},
	author = {Kiscsatári, Laura and Varga, Zoltán and Molnár-Gáspár, Renáta and Görbe, Anikó and Ferdinandy, Péter and Gardi, János and Kahán, Zsuzsanna},
	journal-iso = {MAGYAR ONKOLÓGIA},
	journal = {MAGYAR ONKOLÓGIA},
	volume = {59},
	unique-id = {2902081},
	issn = {0025-0244},
	year = {2015},
	eissn = {2060-0399},
	pages = {169-170},
	orcid-numbers = {Varga, Zoltán/0000-0001-8537-6282; Molnár-Gáspár, Renáta/0000-0001-9673-4532; Görbe, Anikó/0000-0003-4908-1094; Ferdinandy, Péter/0000-0002-6424-6806; Kahán, Zsuzsanna/0000-0002-5021-8775}
}