@article{MTMT:34566488, title = {A COELIAKIA VÁLTOZÓ KLINIKAI MEGJELENÉSÉT BEFOLYÁSOLÓ TÉNYEZŐK}, url = {https://m2.mtmt.hu/api/publication/34566488}, author = {Peresztegi, M and Vereczkei, Zsófia and Farkas, N and Szakács, Z and Bajor, Judit}, journal-iso = {MBA}, journal = {MAGYAR BELORVOSI ARCHIVUM}, volume = {76}, unique-id = {34566488}, issn = {0133-5464}, year = {2023}, pages = {329-329}, orcid-numbers = {Vereczkei, Zsófia/0000-0002-8144-4628} } @article{MTMT:34434496, title = {Discharge protocol in acute pancreatitis: an international survey and cohort analysis}, url = {https://m2.mtmt.hu/api/publication/34434496}, author = {Nagy, Rita and Ocskay, Klementina and Sipos, Zoltán and Szentesi, Andrea Ildikó and Vincze, Áron and Czakó, László and Izbéki, Ferenc and Shirinskaya, Natalia V and Poluektov, Vladimir L and Zolotov, Alexandr N and Zhu, Yin and Xia, Liang and He, Wenhua and Sutton, Robert and Szatmary, Peter and Mukherjee, Rajarshi and Burridge, Isobel Saffron and Wauchope, Emma and Francisco, Elsa and Aparicio, David and Pinto, Bruno and Gomes, António and Nunes, Vitor and Tantau, Vasile Marcel and Sagau, Emanuela Denisa and Tantau, Alina Ioana and Suceveanu, Andra Iulia and Tocia, Cristina and Dumitru, Andrei and Pando, Elizabeth and Alberti, Piero and Cirera, Arturo and Molero, Xavier and Lee, Hong Sik and Jung, Min Kyu and Kim, Eui Joo and Lee, Sanghyub and Rebollo, María Lourdes Ruiz and Nistal, Reyes Busta and Santervas, Sandra Izquierdo and Lesko, Dusan and Soltes, Marek and Radonak, Jozef and Zatorski, Hubert and Małecka-Panas, Ewa and Fabisiak, Adam and Yaroslav, M Susak and Mykhailo, V Maksymenko and Olekcandr, A Tkachenko and Barauskas, Giedrius and Simanaitis, Vytautas and Ignatavicius, Povilas and Jinga, Mariana and Balaban, Vasile-Daniel and Patoni, Cristina and Gong, Liang and Song, Kai and Li, Yunlong and Gonçalves, T Cúrdia and Freitas, Marta and Macedo, Vítor and Vornhuelz, Marlies and Klauss, Sarah and Beyer, Georg and Koksal, Aydin Seref and Tozlu, Mukaddes and Eminler, Ahmet Tarik and Monclús, Nuria Torres and Comas, Eva Pijoan and Oballe, Juan Armando Rodriguez and Nawacki, Łukasz and Głuszek, Stanisław and Rama-Fernández, Alberto and Galego, Marco and de la Iglesia, Daniel and Aykut, Umut Emre and Duman, Deniz Güney and Aslan, Rahmi and Gherbon, Adriana and Deng, Lihui and Huang, Wei and Xia, Qing and Poropat, Goran and Radovan, Anja and Vranić, Luka and Ricci, Claudio and Ingaldi, Carlo and Casadei, Riccardo and Negoi, Ionut and Ciubotaru, Cezar and Iordache, Florin Mihail and Constantinescu, Gabriel and Sandru, Vasile and Altintas, Engin and Balci, Hatice Rizaoglu and Constantino, Júlio and Aveiro, Débora and Pereira, Jorge and Gunay, Suleyman and Misirlioglu Sucan, Seda and Dronov, Oleksiy and Kovalska, Inna and Bush, Nikhil and Rana, Surinder Singh and Chooklin, Serge and Chuklin, Serhii and Saizu, Ionut Adrian and Gheorghe, Cristian and Göltl, Philipp and Hirth, Michael and Mateescu, Radu Bogdan and Papuc, Geanina and Minkov, Georgi Angelov and Enchev, Emil Tihomirov and Mastrangelo, Laura and Jovine, Elio and Chen, Weiwei and Zhu, Quping and Gąsiorowska, Anita and Fabisiak, Natalia and Bezmarevic, Mihailo and Litvin, Andrey and Mottes, Martina Cattani and Choi, Eun Kwang and Bánovčin, Peter and Nosáková, Lenka and Kovacheva-Slavova, Mila Dimitrova and Kchaou, Ali and Tlili, Ahmed and Marino, Marco V and Kusnierz, Katarzyna and Mickevicius, Artautas and Hollenbach, Marcus and Molcan, Pavol and Ioannidis, Orestis and Tokarev, Mark Valerievich and Ince, Ali Tüzün and Semenenko, Ivan Albertovich and Galeev, Shamil and Ramírez-Maldonado, Elena and Sallinen, Ville and Pencik, Petr and Bajor, Judit and Sarlós, Patrícia and Hágendorn, Roland and Gódi, Szilárd and Szabó, Imre and Czimmer, József and Pár, Gabriella and Illés, Anita and Faluhelyi, Nándor and Kanizsai, Péter László and Nagy, Tamás and Mikó, Alexandra and Németh, Balázs and Hamvas, József and Bod, Barnabás and Varga, Márta and Török, Imola and Novák, János and Patai, Árpád and Sümegi, János and Góg, Csaba and Papp, Mária and Erőss, Bálint Mihály and Váncsa, Szilárd and Teutsch, Brigitta and Márta, Katalin and Hegyi, Péter Jenő and Tornai, Tamás and Lázár, Balázs and Hussein, Tamás and Tarján, Dorottya and Lipp, Mónika Bernadett and Kovács, Beáta and Urbán, Orsolya and Fürst, Emese Rita and Tari, Edina and Kocsis, Ibolya and Maurovich-Horvat, Pál and Tihanyi, Balázs and Eperjesi, Orsolya and Kormos, Zita and Deák, Pál Ákos and Párniczky, Andrea and Hegyi, Péter}, doi = {10.1038/s41598-023-48480-z}, journal-iso = {SCI REP}, journal = {SCIENTIFIC REPORTS}, volume = {13}, unique-id = {34434496}, issn = {2045-2322}, abstract = {There are several overlapping clinical practice guidelines in acute pancreatitis (AP), however, none of them contains suggestions on patient discharge. The Hungarian Pancreatic Study Group (HPSG) has recently developed a laboratory data and symptom-based discharge protocol which needs to be validated. (1) A survey was conducted involving all members of the International Association of Pancreatology (IAP) to understand the characteristics of international discharge protocols. (2) We investigated the safety and effectiveness of the HPSG-discharge protocol. According to our international survey, 87.5% (49/56) of the centres had no discharge protocol. Patients discharged based on protocols have a significantly shorter median length of hospitalization (LOH) (7 (5;10) days vs. 8 (5;12) days) p < 0.001), and a lower rate of readmission due to recurrent AP episodes (p = 0.005). There was no difference in median discharge CRP level among the international cohorts (p = 0.586). HPSG-protocol resulted in the shortest LOH (6 (5;9) days) and highest median CRP (35.40 (13.78; 68.40) mg/l). Safety was confirmed by the low rate of readmittance (n = 35; 5%). Discharge protocol is necessary in AP. The discharge protocol used in this study is the first clinically proven protocol. Developing and testifying further protocols are needed to better standardize patients' care.}, year = {2023}, eissn = {2045-2322}, orcid-numbers = {Nagy, Rita/0000-0002-2663-4912; Ocskay, Klementina/0000-0001-5848-2506; Sipos, Zoltán/0000-0001-7845-8116; Szentesi, Andrea Ildikó/0000-0003-2097-6927; Vincze, Áron/0000-0003-2217-7686; Czakó, László/0000-0002-6331-0802; Izbéki, Ferenc/0000-0001-7767-4319; Sarlós, Patrícia/0000-0002-5086-9455; Czimmer, József/0000-0001-7831-3523; Kanizsai, Péter László/0000-0001-7896-2857; Nagy, Tamás/0000-0001-5437-1411; Németh, Balázs/0000-0001-5338-7577; Papp, Mária/0000-0003-3662-4010; Erőss, Bálint Mihály/0000-0003-3658-8427; Váncsa, Szilárd/0000-0002-9347-8163; Teutsch, Brigitta/0000-0002-9530-7886; Márta, Katalin/0000-0002-2213-4865; Tari, Edina/0000-0002-8540-0614; Kocsis, Ibolya/0000-0003-3128-2832; Maurovich-Horvat, Pál/0000-0003-0885-736X; Hegyi, Péter/0000-0003-0399-7259} } @article{MTMT:34140873, title = {Cardiovascular risk factors in coeliac disease (ARCTIC): a protocol of multicentre series of studies}, url = {https://m2.mtmt.hu/api/publication/34140873}, author = {Vereczkei, Zsófia and Imrei, Marcell and Szakács, Zsolt and Kővári, Bálint and Papp, Veronika and Lénárt, Zsuzsanna and Berki, Tímea and Szirmay, Balázs and Borbásné Farkas, Kornélia and Balaskó, Márta and Habon, Tamás and Hegyi, Péter and Bajor, Judit}, doi = {10.1136/bmjopen-2022-068989}, journal-iso = {BMJ OPEN}, journal = {BMJ OPEN}, volume = {13}, unique-id = {34140873}, issn = {2044-6055}, year = {2023}, eissn = {2044-6055}, orcid-numbers = {Vereczkei, Zsófia/0000-0002-8144-4628; Imrei, Marcell/0000-0003-0175-7462; Szakács, Zsolt/0000-0002-7035-941X; Berki, Tímea/0000-0002-0134-8127; Borbásné Farkas, Kornélia/0000-0002-5349-6527; Habon, Tamás/0000-0002-4816-857X; Hegyi, Péter/0000-0003-0399-7259} } @article{MTMT:34095089, title = {Body Mass Index during Gluten-Free Diet in Patients with Celiac Disease}, url = {https://m2.mtmt.hu/api/publication/34095089}, author = {Vereczkei, Zsófia and Dergez, Tímea and Fodor, Zsuzsanna and Szakács, Zsolt and Bajor, Judit}, doi = {10.3390/nu15163517}, journal-iso = {NUTRIENTS}, journal = {NUTRIENTS}, volume = {15}, unique-id = {34095089}, abstract = {The association of clinical variables with body mass index (BMI) and changes experienced during a gluten-free diet (GFD) in celiac disease (CD) is not well established. In this retrospective cohort study, we aimed to investigate factors aligned with baseline and a follow-up regarding BMI in CD cases diagnosed at the University of Pécs (Hungary). Data were collected regarding gender, age, clinical presentation, histology, serology, extraintestinal manifestations, and BMI upon diagnosis and during follow-up. To compare variables with baseline BMI and BMI changes in short-, intermediate-, and long-term periods, we applied univariate analyses. A total of 192 CD patients were included. Males had significantly higher mean BMI when compared with females at diagnosis (22.9 ± 4.1 vs. 21.4 ± 4.3 kg/m2, p = 0.041) and during follow-up (p = 0.031, p = 0.029, and p = 0.033 for short-, intermediate-, and long-term follow-ups, respectively). Non-classical CD patients experienced higher mean BMI at diagnosis (22.9 ± 4.0 vs. 20.7 ± 4.4 kg/m2, p < 0.001) and following long-term follow-up (24.5 ± 3.2 vs. 22.6 ± 3.4 kg/m2, p = 0.039) than classical patients. In conclusion, although the mean BMI remained in the normal range, it increased significantly during follow-up, even at the short-term follow-up. This change was characteristic for non-classical cases and males on the long-term follow-ups.}, year = {2023}, eissn = {2072-6643}, orcid-numbers = {Vereczkei, Zsófia/0000-0002-8144-4628; Szakács, Zsolt/0000-0002-7035-941X} } @article{MTMT:33728537, title = {Clinical Presentation Is Dependent on Age and Calendar Year of Diagnosis in Celiac Disease : A Hungarian Cross-Sectional Study}, url = {https://m2.mtmt.hu/api/publication/33728537}, author = {Szakács, Zsolt and Borbásné Farkas, Kornélia and Nagy, Enikő and Bencs, Réka and Vereczkei, Zsófia and Bajor, Judit}, doi = {10.3390/jpm13030487}, journal-iso = {J PERS MED}, journal = {JOURNAL OF PERSONALIZED MEDICINE}, volume = {13}, unique-id = {33728537}, abstract = {International trends indicate that celiac disease (CeD) is becoming more common, while the clinical presentation of CeD tends to change. We aimed to investigate factors associated with the clinical presentation of CeD. We reviewed all CeD cases diagnosed at our tertiary center, University of Pécs (Hungary), between 1992 and 2019. We collected data of verified CeD patients on clinical presentations (classified by the Oslo Classification), the age at and calendar year of diagnosis, and sex, serology and histology at diagnosis. To assess the associations of baseline variables with clinical presentations, we applied univariate and multivariate (binary logistic regression) statistics. A total of 738 CeD patients were eligible for inclusion. In the univariate analysis, patients with classical CeD were more common in the latest calendar period (p < 0.001) and tended to be older (p = 0.056), but we failed to observe a significant association between the clinical presentation and sex, serology or histology at diagnosis. In the multivariate analysis, only age at diagnosis and calendar year were independently associated with clinical presentations (OR = 1.02, CI: 1.01-1.04 and OR = 0.93, CI: 0.89-0.98, respectively). Our findings confirmed that classical CeD is independently associated with age at diagnosis and calendar year of diagnosis of CeD, whereas other parameters were not significantly associated with clinical presentations.}, keywords = {celiac disease; clinical presentation; clinical phenotype; calendar year; children and adults}, year = {2023}, eissn = {2075-4426}, orcid-numbers = {Szakács, Zsolt/0000-0002-7035-941X; Borbásné Farkas, Kornélia/0000-0002-5349-6527; Vereczkei, Zsófia/0000-0002-8144-4628} } @article{MTMT:33636629, title = {Suprapapillary Biliary Stents Have Longer Patency Times than Transpapillary Stents-A Systematic Review and Meta-Analysis.}, url = {https://m2.mtmt.hu/api/publication/33636629}, author = {Kovács, Norbert and Pécsi, Dániel and Sipos, Zoltán and Borbásné Farkas, Kornélia and Földi, Mária and Hegyi, Péter and Bajor, Judit and Erőss, Bálint Mihály and Márta, Katalin and Mikó, Alexandra and Rakonczay, Zoltán and Sarlós, Patrícia and Ábrahám, Szabolcs and Vincze, Áron}, doi = {10.3390/jcm12030898}, journal-iso = {J CLIN MED}, journal = {JOURNAL OF CLINICAL MEDICINE}, volume = {12}, unique-id = {33636629}, abstract = {Endoscopic biliary stent placement is a minimally invasive intervention for patients with biliary strictures. Stent patency and function time are crucial factors. Suprapapillary versus transpapillary stent positioning may contribute to stent function time, so a meta-analysis was performed in this comparison.A comprehensive literature search was conducted in the CENTRAL, Embase, and MEDLINE databases to find data on suprapapillary stent placement compared to the transpapillary method via endoscopic retrograde cholangiopancreatography in cases of biliary stenosis of any etiology and any stent type until December 2020. We carried out a meta-analysis focusing on the following outcomes: stent patency, stent migration, rate of cholangitis and pancreatitis, and other reported complications.Three prospective and ten retrospective studies involving 1028 patients were included. Suprapapillary stent placement appeared to be superior to transpapillary stent positioning in patency (weighted mean difference = 50.23 days, 95% CI: 8.56, 91.98; p = 0.0.018). In a subgroup analysis of malignant indications, suprapapillary positioning showed a lower rate of cholangitis (OR: 0.34, 95% CI: 0.13, 0.93; p = 0.036). Another subgroup analysis investigating metal stents in a suprapapillary position resulted in a lower rate of pancreatitis (OR: 0.16, 95% CI: 0.03, 0.95; p = 0.043) compared to transpapillary stent placement. There was no difference in stent migration rates between the two groups (OR: 0.67, 95% CI: 0.17, 2.72; p = 0.577).Based on our results, suprapapillary biliary stenting has longer stent patency. Moreover, the stent migration rate did not differ between the suprapapillary and transpapillary groups.}, keywords = {endoscopy; Stent; ERCP; intraductal; inside; [Meta-analysis]}, year = {2023}, eissn = {2077-0383}, orcid-numbers = {Pécsi, Dániel/0000-0003-0499-6004; Sipos, Zoltán/0000-0001-7845-8116; Borbásné Farkas, Kornélia/0000-0002-5349-6527; Hegyi, Péter/0000-0003-0399-7259; Erőss, Bálint Mihály/0000-0003-3658-8427; Márta, Katalin/0000-0002-2213-4865; Rakonczay, Zoltán/0000-0002-1499-3416; Sarlós, Patrícia/0000-0002-5086-9455; Ábrahám, Szabolcs/0000-0002-2191-1714; Vincze, Áron/0000-0003-2217-7686} } @article{MTMT:33079004, title = {Az ételintoleranciák diagnosztikájának és kezelésének fontosabb szempontjai}, url = {https://m2.mtmt.hu/api/publication/33079004}, author = {Bajor, Judit}, journal-iso = {HÁZIORVOS TOVÁBBKÉPZŐ SZEMLE}, journal = {HÁZIORVOS TOVÁBBKÉPZŐ SZEMLE}, volume = {27}, unique-id = {33079004}, issn = {1219-8641}, year = {2022}, pages = {433-438} } @article{MTMT:32925017, title = {Selective intraoperative cholangiography should be considered over routine intraoperative cholangiography during cholecystectomy : a systematic review and meta-analysis}, url = {https://m2.mtmt.hu/api/publication/32925017}, author = {Kovács, Norbert and Németh, Dávid and Földi, Mária and Nagy, Bernadette and Bunduc, Stefania and Hegyi, Péter and Bajor, Judit and Müller, Katalin Eszter and Vincze, Áron and Erőss, Bálint Mihály and Ábrahám, Szabolcs}, doi = {10.1007/s00464-022-09267-x}, journal-iso = {SURG ENDOSC}, journal = {SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES}, volume = {36}, unique-id = {32925017}, issn = {0930-2794}, abstract = {Decades of debate surround the use of intraoperative cholangiography (IOC) during cholecystectomy. To the present day, the role of IOC is controversial as regards decreasing the rate of bile duct injury (BDI). We aimed to review and analyse the available literature on the benefits of IOC during cholecystectomy.A systematic literature search was performed until 19 October 2020 in five databases using the following search keys: cholangiogra* and cholecystectomy. The primary outcomes were BDI and retained stone rate. To investigate the differences between the groups (routine IOC vs selective IOC and IOC vs no IOC), we calculated weighted mean differences (WMD) for continuous outcomes and relative risks (RR) for dichotomous outcomes, with 95% confidence intervals (CI).Of the 19,863 articles, 38 were selected and 32 were included in the quantitative synthesis. Routine IOC showed no superiority compared to selective IOC in decreasing BDI (RR = 0.91, 95% CI 0.66; 1.24). Comparing IOC and no IOC, no statistically significant differences were found in the case of BDI, retained stone rate, readmission rate, and length of hospital stay. We found an increased risk of conversion rate to open surgery in the no IOC group (RR = 0.64, CI 0.51; 0.78). The operation time was significantly longer in the IOC group compared to the no IOC group (WMD = 11.25 min, 95% CI 6.57; 15.93).Our findings suggest that IOC may not be indicated in every case, however, the evidence is very uncertain. Further good quality research is required to address this question.}, keywords = {Cholecystectomy; Cholangiography; Laparoscopic cholecystectomy; BDI; bile duct injury; IOC; [Meta-analysis]}, year = {2022}, eissn = {1432-2218}, pages = {7126-7139}, orcid-numbers = {Hegyi, Péter/0000-0003-0399-7259; Müller, Katalin Eszter/0000-0001-5355-4224; Vincze, Áron/0000-0003-2217-7686; Erőss, Bálint Mihály/0000-0003-3658-8427; Ábrahám, Szabolcs/0000-0002-2191-1714} } @article{MTMT:32865751, title = {EASY-APP: An artificial intelligence model and application for early and easy prediction of severity in acute pancreatitis}, url = {https://m2.mtmt.hu/api/publication/32865751}, author = {Kui, Balázs and Pintér, József and Molontay, Roland and Nagy, Marcell and Borbásné Farkas, Kornélia and Gede, Noémi and Vincze, Áron and Bajor, Judit and Gódi, Szilárd and Czimmer, József and Szabó, Imre and Illés, Anita and Sarlós, Patrícia and Hágendorn, Roland and Pár, Gabriella and Papp, Mária and Vitális, Zsuzsanna and Kovács, György and Fehér, Eszter and Földi, Ildikó and Izbéki, Ferenc and Gajdán, László and Fejes, Roland and Németh, Balázs and Török, Imola and Farkas, Hunor and Mickevicius, Artautas and Sallinen, Ville and Galeev, Shamil and Ramírez-Maldonado, Elena and Párniczky, Andrea and Erőss, Bálint Mihály and Hegyi, Péter Jenő and Márta, Katalin and Váncsa, Szilárd and Sutton, Robert and Szatmary, Peter and Latawiec, Diane and Halloran, Chris and de-Madaria, Enrique and Pando, Elizabeth and Alberti, Piero and Gómez-Jurado, Maria José and Tantau, Alina and Szentesi, Andrea Ildikó and Hegyi, Péter}, doi = {10.1002/ctm2.842}, journal-iso = {CLIN TRANSL MED}, journal = {CLINICAL AND TRANSLATIONAL MEDICINE}, volume = {12}, unique-id = {32865751}, issn = {2001-1326}, abstract = {Acute pancreatitis (AP) is a potentially severe or even fatal inflammation of the pancreas. Early identification of patients at high risk for developing a severe course of the disease is crucial for preventing organ failure and death. Most of the former predictive scores require many parameters or at least 24 h to predict the severity; therefore, the early therapeutic window is often missed.The early achievable severity index (EASY) is a multicentre, multinational, prospective and observational study (ISRCTN10525246). The predictions were made using machine learning models. We used the scikit-learn, xgboost and catboost Python packages for modelling. We evaluated our models using fourfold cross-validation, and the receiver operating characteristic (ROC) curve, the area under the ROC curve (AUC), and accuracy metrics were calculated on the union of the test sets of the cross-validation. The most critical factors and their contribution to the prediction were identified using a modern tool of explainable artificial intelligence called SHapley Additive exPlanations (SHAP).The prediction model was based on an international cohort of 1184 patients and a validation cohort of 3543 patients. The best performing model was an XGBoost classifier with an average AUC score of 0.81 ± 0.033 and an accuracy of 89.1%, and the model improved with experience. The six most influential features were the respiratory rate, body temperature, abdominal muscular reflex, gender, age and glucose level. Using the XGBoost machine learning algorithm for prediction, the SHAP values for the explanation and the bootstrapping method to estimate confidence, we developed a free and easy-to-use web application in the Streamlit Python-based framework (http://easy-app.org/).The EASY prediction score is a practical tool for identifying patients at high risk for severe AP within hours of hospital admission. The web application is available for clinicians and contributes to the improvement of the model.}, keywords = {Artificial intelligence; Acute pancreatitis; severity prediction}, year = {2022}, eissn = {2001-1326}, orcid-numbers = {Molontay, Roland/0000-0002-0666-5279; Borbásné Farkas, Kornélia/0000-0002-5349-6527; Vincze, Áron/0000-0003-2217-7686; Czimmer, József/0000-0001-7831-3523; Sarlós, Patrícia/0000-0002-5086-9455; Papp, Mária/0000-0003-3662-4010; Vitális, Zsuzsanna/0000-0001-8198-5312; Izbéki, Ferenc/0000-0001-7767-4319; Németh, Balázs/0000-0001-5338-7577; Erőss, Bálint Mihály/0000-0003-3658-8427; Márta, Katalin/0000-0002-2213-4865; Váncsa, Szilárd/0000-0002-9347-8163; Szentesi, Andrea Ildikó/0000-0003-2097-6927; Hegyi, Péter/0000-0003-0399-7259} } @article{MTMT:32849790, title = {In-Hospital Patient Education Markedly Reduces Alcohol Consumption after Alcohol-Induced Acute Pancreatitis.}, url = {https://m2.mtmt.hu/api/publication/32849790}, author = {Nagy, Rita and Ocskay, Klementina and Váradi, Alex and Papp, Mária and Vitális, Zsuzsanna and Izbéki, Ferenc and Boros, Eszter and Gajdán, László and Szentesi, Andrea Ildikó and Erőss, Bálint Mihály and Hegyi, Péter Jenő and Vincze, Áron and Bajor, Judit and Sarlós, Patrícia and Mikó, Alexandra and Márta, Katalin and Pécsi, Dániel and Párniczky, Andrea and Hegyi, Péter}, doi = {10.3390/nu14102131}, journal-iso = {NUTRIENTS}, journal = {NUTRIENTS}, volume = {14}, unique-id = {32849790}, abstract = {Although excessive alcohol consumption is by far the most frequent cause of recurrent acute pancreatitis (AP) cases, specific therapy is still not well established to prevent recurrence. Generally, psychological therapy (e.g., brief intervention (BI)) is the cornerstone of cessation programs; however, it is not yet widely used in everyday practice. We conducted a post-hoc analysis of a prospectively collected database. Patients suffering from alcohol-induced AP between 2016 and 2021 received 30 min BI by a physician. Patient-reported alcohol consumption, serum gamma-glutamyl-transferase (GGT) level, and mean corpuscular volume (MCV) of red blood cells were collected on admission and at the 1-month follow-up visit to monitor patients' drinking habits. Ninety-nine patients with alcohol-induced AP were enrolled in the study (mean age: 50 ± 11, 89% male). A significant decrease was detected both in mean GGT value (294 ± 251 U/L vs. 103 ± 113 U/L, p < 0.001) and in MCV level (93.7 ± 5.3 U/L vs. 92.1 ± 5.1 U/L, p < 0.001) in patients with elevated on-admission GGT levels. Notably, 79% of the patients (78/99) reported alcohol abstinence at the 1-month control visit. Brief intervention is an effective tool to reduce alcohol consumption and to prevent recurrent AP. Longitudinal randomized clinical studies are needed to identify the adequate structure and frequency of BIs in alcohol-induced AP.}, keywords = {Recurrence; ALCOHOL; Acute pancreatitis; Brief intervention; gamma-glutamyl transferase}, year = {2022}, eissn = {2072-6643}, orcid-numbers = {Nagy, Rita/0000-0002-2663-4912; Ocskay, Klementina/0000-0001-5848-2506; Váradi, Alex/0000-0001-8229-6340; Papp, Mária/0000-0003-3662-4010; Vitális, Zsuzsanna/0000-0001-8198-5312; Szentesi, Andrea Ildikó/0000-0003-2097-6927; Erőss, Bálint Mihály/0000-0003-3658-8427; Vincze, Áron/0000-0003-2217-7686; Sarlós, Patrícia/0000-0002-5086-9455; Márta, Katalin/0000-0002-2213-4865; Pécsi, Dániel/0000-0003-0499-6004; Hegyi, Péter/0000-0003-0399-7259} }