@mastersthesis{MTMT:2785868,
	title = {Iron oxide nanoparticles and their toxicological effects: in vivo and in vitro studies},
	url = {https://m2.mtmt.hu/api/publication/2785868},
	author = {Szalay, Brigitta},
	doi = {10.14232/phd.1422},
	publisher = {SZTE},
	unique-id = {2785868},
	year = {2012}
}

@inproceedings{MTMT:1905238,
	title = {In vitro mutagenicity evaluation of iron oxide nanoparticles by the bacterial reverse mutation assay},
	url = {https://m2.mtmt.hu/api/publication/1905238},
	author = {Szalay, Brigitta and Vezér, Tünde},
	booktitle = {Proceedings of the 17th International Symposium on Analytical and Environmental Problems},
	unique-id = {1905238},
	year = {2012},
	pages = {275-278}
}

@article{MTMT:1847652,
	title = {Potential toxic effects of iron oxide nanoparticles in in vivo and in vitro experiments},
	url = {https://m2.mtmt.hu/api/publication/1847652},
	author = {Szalay, Brigitta and Tatrai, E and Nyírő, Gábor and Vezér, Tünde and Dura, G},
	doi = {10.1002/jat.1779},
	journal-iso = {J APPL TOXICOL},
	journal = {JOURNAL OF APPLIED TOXICOLOGY},
	volume = {32},
	unique-id = {1847652},
	issn = {0260-437X},
	abstract = {The aim of this study was to determine the potential toxic effects of iron(II,III)oxide nanoparticles (IONPs). In in vivo experiments, the toxic effects of IONPs were monitored in adult male Wistar rats by morphological methods after a single intratracheal instillation. For the control group 1 ml of physiological saline per animal was given, and the treatment group received the same volume of a suspension containing 1 and 5 mg kg(-1) body weight IONPs. Lungs and internal organs underwent histopathological examination after 1, 3, 7, 14 and 30 days. The mutagenic effect of these nanoparticles was evaluated by the bacterial reverse mutation assay on Salmonella typhimurium TA98, TA100, TA1535 and TA1537 strains, and on Escherichia coli WP2uvrA strain, in the presence and absence of the mammalian metabolic activation system S9. The in vitro cytotoxic effect of IONPs was also examined in Vero cells after short-term (4 h) and long-term (24 h) exposure. There were no pathological changes in examined internal organs, except a very weak pulmonary fibrosis developing by the end of the first month in the treated rats. While in vitro MTT assay showed a moderate cytotoxic effect, IONPs proved to be devoid of mutagenic effect in the bacterial systems tested. The results may be a useful extension of our knowledge on the safety of magnetite nanoparticles in view of their possible medical applications, such as in hyperthermia and magnetic resonance imaging. Copyright (c) 2011 John Wiley & Sons, Ltd.},
	year = {2012},
	eissn = {1099-1263},
	pages = {446-453},
	orcid-numbers = {Nyírő, Gábor/0000-0002-0248-0007}
}

@article{MTMT:1905226,
	title = {Nikkel-, vas- és cinkoxid nanopartikulumok tüdősejtekre gyakorolt membránkárosító hatása},
	url = {https://m2.mtmt.hu/api/publication/1905226},
	author = {Szalay, Brigitta and Tátrai, E and Pándics, Tamás and Dura, Gy},
	journal-iso = {EGÉSZSÉGTUDOMÁNY},
	journal = {EGÉSZSÉGTUDOMÁNY},
	volume = {54},
	unique-id = {1905226},
	issn = {0013-2268},
	keywords = {Vas; környezetszennyezés; mérgezés; TÜDŐ; OXIDOK},
	year = {2010},
	pages = {52-59}
}

@article{MTMT:1905216,
	title = {Vas-oxid nanorészecskék tüdőtoxicitása},
	url = {https://m2.mtmt.hu/api/publication/1905216},
	author = {Szalay, Brigitta and Brózik, M and Kováčiková, Z and Tátrai, E and Pándics, Tamás},
	journal-iso = {EGÉSZSÉGTUDOMÁNY},
	journal = {EGÉSZSÉGTUDOMÁNY},
	volume = {53},
	unique-id = {1905216},
	issn = {0013-2268},
	keywords = {Vas; mérgezés; IMMUNGLOBULINOK; KÖRNYEZETEGÉSZSÉGÜGY; OXIDOK},
	year = {2009},
	pages = {97-109}
}

@article{MTMT:1283183,
	title = {Subacute intratracheal exposure of rats to manganese nanoparticles. Behavioral, electrophysiological, and general toxicological effects},
	url = {https://m2.mtmt.hu/api/publication/1283183},
	author = {Sárközi, L and Horváth, E and Kónya, Zoltán and Kiricsi, Imre and Szalay, Brigitta and Vezér, Tünde and Papp, András},
	doi = {10.1080/08958370902939406},
	journal-iso = {INHAL TOXICOL},
	journal = {INHALATION TOXICOLOGY},
	volume = {21},
	unique-id = {1283183},
	issn = {0895-8378},
	abstract = {The toxicity of manganese-containing airborne particles is an important occupational and environmental problem. In this work, adult male Wistar rats were treated with a nanosuspension of MnO2 of approximately 23nm nominal particle diameter, instilled into the trachea for 3, 6, and 9wk in doses of 2.63 and 5.26mg Mn/kg. The animals' body weight was checked weekly. At the end of treatment, the rats' spontaneous motility was tested in an open field box. Then, spontaneous and stimulus-evoked cortical activity and action potential of the tail nerve were recorded in urethane anesthesia. The rats were finally dissected, organs weights were measured, and the presence of excess Mn in lung and brain samples was determined using scanning electron microscopy with energy-dispersive x-ray spectroscopy. While control rats had normal weight gain, the body weights of the treated rats ceased to grow fürom wk 6 on. The relative weight of the lungs increased in the treated rats, and that of the liver decreased, in a dose- and time-dependent manner; Mn was detected in their lung and brain samples. In the open field activity, the percentage of ambulation and rearing decreased while local activity and immobility increased. The latency of the evoked potentials was lengthened, and the conduction velocity of the tail nerve decreased. These results indicate that the Mn content of instilled nanoparticles had access fürom the airways to the brain, and the resulting damage could be investigated in animals using neuro-functional and general toxicological endpoints. © 2009 Informa UK Ltd.},
	year = {2009},
	eissn = {1091-7691},
	pages = {83-91},
	orcid-numbers = {Kónya, Zoltán/0000-0002-9406-8596; Papp, András/0000-0003-0485-0806}
}

@article{MTMT:1905157,
	title = {Effects of iron oxide nanoparticles on pulmonary morphology, redox system, production of immunoglobulins and chemokins in rats: In vivo and In vitro studies},
	url = {https://m2.mtmt.hu/api/publication/1905157},
	author = {Szalay, Brigitta and Kováčikova, Z and Brózik, M and Pándics, Tamás and Tátrai, E},
	journal-iso = {CENTR EUR J OCUPP ENVIRON MED},
	journal = {CENTRAL EUROPEAN JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE},
	volume = {14},
	unique-id = {1905157},
	issn = {1219-1221},
	year = {2008},
	pages = {149-164}
}

@{MTMT:1905073,
	title = {Nanotechnology. Toxicological Issues and Environmental Safety},
	url = {https://m2.mtmt.hu/api/publication/1905073},
	author = {Dura, Gy and Szalay, Brigitta},
	booktitle = {Nanotechnology},
	unique-id = {1905073},
	year = {2007},
	pages = {271-276}
}