@article{MTMT:34523817, title = {Tumour regression predicts better response to interferon therapy in melanoma patients. a retrospective single centre study.}, url = {https://m2.mtmt.hu/api/publication/34523817}, author = {Mezőlaki, Noémi and Baltás, Eszter and Ócsai, Henriette and Varga, Anita and Korom, Irma and Varga, Erika and Németh, István Balázs and Kis, Erika and Varga, János and Kocsis, Ádám László and Gyulai, Rolland Péter and Bukva, Mátyás and Kemény, Lajos and Oláh, Judit Magdolna}, doi = {10.1097/CMR.0000000000000935}, journal-iso = {MELANOMA RES}, journal = {MELANOMA RESEARCH}, volume = {34}, unique-id = {34523817}, issn = {0960-8931}, abstract = {We hypothesise that regression may have an impact on the effectiveness of adjuvant IFN therapy, based on its role in the host immune response. Our purpose is to investigate regression and ulceration as prognostic factors in case of interferon-alpha (IFN)-treated melanoma patients. We followed 357 IFN-treated melanoma patients retrospectively, investigating progression-free survival (PFS) and overall survival (OS) depending on the presence of ulceration and regression. A Kaplan-Meier analysis was performed, and we used a Cox regression analysis to relate risk factors. The survival function of the Cox regression was used to measure the effect of regression and ulceration on PFS and OS depending on the Breslow thickness (T1-T4) of the primary tumour. Regression was significantly positively related to PFS ( P = 0.0018, HR = 0.352) and OS ( P = 0.0112, HR = 0.380), while ulceration showed a negative effect (PFS: P = 0.0001, HR = 2.629; OS: P = 0.0003, HR = 2.388). They influence survival independently. The most favourable outcome was measured in the regressed/non-ulcerated group, whereas the worse was in the non-regressed/ulcerated one. Of risk factors, Breslow thickness is the most significant predictor. The efficacy of regression is regardless of Breslow thickness, though the more favourable the impact of regression was in the thicker primary lesions. Our results indicate that regression is associated with a more favourable outcome for IFN-treated melanoma patients, whereas ulceration shows an inverse relation. Further studies are needed to analyse the survival benefit of regression in relation to innovative immune checkpoint inhibitors.}, year = {2024}, eissn = {1473-5636}, pages = {54-62}, orcid-numbers = {Baltás, Eszter/0000-0003-0357-7393; Gyulai, Rolland Péter/0000-0002-3286-8846; Bukva, Mátyás/0000-0002-5225-0285; Kemény, Lajos/0000-0002-2119-9501} } @article{MTMT:34513656, title = {Arcra lokalizálódó bőrtünet differenciáldiagnosztikája, esetismertetés}, url = {https://m2.mtmt.hu/api/publication/34513656}, author = {Kovács, Nóra and Baltás, Eszter and Belső, Nóra and Rózsa, Petra and Mihályi, Lilla and Varga, Erika and Korom, Irma and Kemény, Lajos and Gyulai, Rolland Péter and Csörgő Sándorné Bata, Zsuzsanna}, journal-iso = {BVSZ}, journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE}, volume = {99}, unique-id = {34513656}, issn = {0006-7768}, year = {2023}, eissn = {2064-261X}, pages = {427-428}, orcid-numbers = {Baltás, Eszter/0000-0003-0357-7393; Mihályi, Lilla/0000-0001-6215-4572; Kemény, Lajos/0000-0002-2119-9501; Gyulai, Rolland Péter/0000-0002-3286-8846; Csörgő Sándorné Bata, Zsuzsanna/0000-0002-3732-1743} } @article{MTMT:33928967, title = {Biológiai és célzott terápiák bőrpathologiai vonatkozásai a mindennapi gyakorlatban}, url = {https://m2.mtmt.hu/api/publication/33928967}, author = {Varga, Erika and Horváth, Zsófia and Németh, István Balázs and Korom, Irma}, doi = {10.7188/bvsz.2023.99.2.7}, journal-iso = {BVSZ}, journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE}, volume = {99}, unique-id = {33928967}, issn = {0006-7768}, year = {2023}, eissn = {2064-261X}, pages = {125-131} } @CONFERENCE{MTMT:34136116, title = {Melanoma malignum PD-1 gátló kezelése során észlelt bullosus pemphigoid két esetünk kapcsán}, url = {https://m2.mtmt.hu/api/publication/34136116}, author = {Kovács, Nóra Kata and Mihályi, Lilla and Ócsai, Henriette and Varga, Erika and Korom, Irma and Csörgő Sándorné Bata, Zsuzsanna and Kemény, Lajos and Oláh, Judit and Baltás, Eszter}, booktitle = {A Magyar Allergológiai és Klinikai Immunológiai Társaság 50. kongresszusa : MAKIT 2022}, unique-id = {34136116}, year = {2022}, pages = {1}, orcid-numbers = {Mihályi, Lilla/0000-0001-6215-4572; Csörgő Sándorné Bata, Zsuzsanna/0000-0002-3732-1743; Baltás, Eszter/0000-0003-0357-7393} } @article{MTMT:33292177, title = {A Merkel sejtes karcinóma multimodális kezelési lehetőségei [Multimodal treatment options for Merkel cell carcinoma]}, url = {https://m2.mtmt.hu/api/publication/33292177}, author = {Ágoston, Dóra and Hánis, Csilla and Ócsai, Henriette and Csányi, Ildikó and Varga, Erika and Korom, Irma and Németh, István Balázs and Kis, Erika and Kemény, Lajos and Oláh, Judit Magdolna and Baltás, Eszter}, doi = {10.7188/bvsz.2022.98.5.1}, journal-iso = {BVSZ}, journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE}, volume = {98}, unique-id = {33292177}, issn = {0006-7768}, year = {2022}, eissn = {2064-261X}, pages = {240-246}, orcid-numbers = {Csányi, Ildikó/0000-0002-0766-5289; Kemény, Lajos/0000-0002-2119-9501; Baltás, Eszter/0000-0003-0357-7393} } @article{MTMT:33101722, title = {Melanoma malignum PD-1 gátló kezelése során észlelt bullosus pemphigoid két esetünk kapcsán}, url = {https://m2.mtmt.hu/api/publication/33101722}, author = {Kovács, Nóra Kata and Mihályi, Lilla and Ócsai, Henriette and Varga, Anita and Varga, Erika and Korom, Irma and Kemény, Lajos and Csörgő Sándorné Bata, Zsuzsanna and Oláh, Judit Magdolna and Baltás, Eszter}, journal-iso = {BVSZ}, journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE}, volume = {97}, unique-id = {33101722}, issn = {0006-7768}, year = {2021}, eissn = {2064-261X}, pages = {304-304}, orcid-numbers = {Mihályi, Lilla/0000-0001-6215-4572; Kemény, Lajos/0000-0002-2119-9501; Csörgő Sándorné Bata, Zsuzsanna/0000-0002-3732-1743; Baltás, Eszter/0000-0003-0357-7393} } @misc{MTMT:32084198, title = {A Covid-19 mRNS vakcinák okozta bőrtünetek irodalmi összefoglalása és saját eseteink bemutatása}, url = {https://m2.mtmt.hu/api/publication/32084198}, author = {Kovács, Nóra Kata and Németh, István Balázs and Korom, Irma and Mihályi, Lilla and Rózsa, Petra and Csoma, Zsanett and Bata-Csörgő, Zsuzsanna and Kemény, Lajos}, unique-id = {32084198}, year = {2021}, orcid-numbers = {Mihályi, Lilla/0000-0001-6215-4572; Csoma, Zsanett/0000-0003-0376-9061} } @article{MTMT:31868124, title = {Biológiai terápiák bőrgyógyászati mellékhatásai}, url = {https://m2.mtmt.hu/api/publication/31868124}, author = {Korom, Irma and Varga, Erika}, journal-iso = {BVSZ}, journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE}, volume = {96}, unique-id = {31868124}, issn = {0006-7768}, year = {2020}, eissn = {2064-261X}, pages = {287-287} } @article{MTMT:31868114, title = {Biomarkerek melanomában}, url = {https://m2.mtmt.hu/api/publication/31868114}, author = {Németh, István Balázs and Korom, Irma and Ócsai, Henriette and Varga, Anita and Baltás, Eszter and Oláh, Judit Magdolna and Kemény, Lajos and Varga, Erika}, journal-iso = {BVSZ}, journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE}, volume = {96}, unique-id = {31868114}, issn = {0006-7768}, year = {2020}, eissn = {2064-261X}, pages = {287-287}, orcid-numbers = {Baltás, Eszter/0000-0003-0357-7393; Kemény, Lajos/0000-0002-2119-9501} } @article{MTMT:31821603, title = {A mycosis fungoides prognosztikai faktorai két betegünk kapcsán [Prognostic markers of mycosis fungoides by means of two cases]}, url = {https://m2.mtmt.hu/api/publication/31821603}, author = {Csányi, Ildikó and Ócsai, Henriette and Korom, Irma and Varga, Erika and Varga, Anita and Hideghéty, Katalin and Krenács, László and Bagdi, Enikő and Gurbity Pálfi, Timea and Piukovics, Klára and Borbényi, Zita and Kemény, Lajos and Oláh, Judit Magdolna and Baltás, Eszter}, doi = {10.7188/bvsz.2020.96.5.3}, journal-iso = {BVSZ}, journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE}, volume = {96}, unique-id = {31821603}, issn = {0006-7768}, year = {2020}, eissn = {2064-261X}, pages = {223-229}, orcid-numbers = {Csányi, Ildikó/0000-0002-0766-5289; Hideghéty, Katalin/0000-0001-7080-2365; Piukovics, Klára/0000-0003-4480-3131; Kemény, Lajos/0000-0002-2119-9501; Baltás, Eszter/0000-0003-0357-7393} }