@article{MTMT:33253080,
	title = {Liquid biopsziával egy targetált kezeléssel befolyásolt tüdőtumor evolúciójának nyomában},
	url = {https://m2.mtmt.hu/api/publication/33253080},
	author = {Szalontai, Klára Margit and Priskin, Katalin and Giricz, Zsófia and Mező, Béla and Pintér, Lajos and Pankotai, Tibor and Tiszlavicz, László and Sükösd, Farkas},
	journal-iso = {KLINIKAI ONKOLÓGIA},
	journal = {KLINIKAI ONKOLÓGIA},
	volume = {9},
	unique-id = {33253080},
	issn = {2064-5058},
	year = {2022},
	pages = {29-29},
	orcid-numbers = {Pankotai, Tibor/0000-0001-9810-5465; Tiszlavicz, László/0000-0003-1134-6587}
}

@article{MTMT:33253071,
	title = {Az újgenerációs szekvenáláson innen és túl: a tumorpanelek elemzéséből leszűrhető információk},
	url = {https://m2.mtmt.hu/api/publication/33253071},
	author = {Sükösd, Farkas and Priskin, Katalin and Giricz, Zsófia and Mező, Béla and Pintér, Lajos and Pankotai, Tibor and Haracska, Lajos},
	journal-iso = {KLINIKAI ONKOLÓGIA},
	journal = {KLINIKAI ONKOLÓGIA},
	volume = {9},
	unique-id = {33253071},
	issn = {2064-5058},
	year = {2022},
	pages = {16-16},
	orcid-numbers = {Pankotai, Tibor/0000-0001-9810-5465}
}

@{MTMT:33089595,
	title = {UNDERSTANDING THE EFFECTS OF COVID-19 ON THE MICROBIOME USING BIOINFORMATICS AND MACHINE LEARNING},
	url = {https://m2.mtmt.hu/api/publication/33089595},
	author = {Takács, Bertalan Vilmos and Gyuris, Zoltán and Pintér, Lajos and Visnyovszki, Ádám and Enyedi, Márton Zsolt and Hajdú, Edit and Haracska, Lajos},
	booktitle = {„FIBOK 2022” : Fiatal Biotechnológusok V. Országos Konferenciája},
	unique-id = {33089595},
	year = {2022}
}

@article{MTMT:32606165,
	title = {The Rad5 Helicase and RING Domains Contribute to Genome Stability through their Independent Catalytic Activities},
	url = {https://m2.mtmt.hu/api/publication/32606165},
	author = {Tóth, Róbert and Balogh, Dávid and Pintér, Lajos and Jaksa, G. and Szeplaki, B. and Gráf, Alexandra and Győrfy, Zsuzsanna and Enyedi, Márton Zsolt and Kiss, Ernő and Haracska, Lajos and Unk, Ildikó},
	doi = {10.1016/j.jmb.2021.167437},
	journal-iso = {J MOL BIOL},
	journal = {JOURNAL OF MOLECULAR BIOLOGY},
	volume = {434},
	unique-id = {32606165},
	issn = {0022-2836},
	abstract = {Genomic stability is compromised by DNA damage that obstructs replication. Rad5 plays a prominent role in DNA damage bypass processes that evolved to ensure the continuation of stalled replication. Like its human orthologs, the HLTF and SHPRH tumor suppressors, yeast Rad5 has a RING domain that supports ubiquitin ligase activity promoting PCNA polyubiquitylation and a helicase domain that in the case of HLTF and Rad5 was shown to exhibit an ATPase-linked replication fork reversal activity. The RING domain is embedded in the helicase domain, confusing their separate investigation and the understanding of the exact role of Rad5 in DNA damage bypass. Particularly, it is still debated whether the helicase domain plays a catalytic or a non-enzymatic role during error-free damage bypass and whether it facilitates a function separately from the RING domain. In this study, through in vivo and in vitro characterization of domain-specific mutants, we delineate the contributions of the two domains to Rad5 function. Yeast genetic experiments and whole-genome sequencing complemented with biochemical assays demonstrate that the ubiquitin ligase and the ATPase-linked activities of Rad5 exhibit independent catalytic activities in facilitating separate pathways during error-free lesion bypass. Our results also provide important insights into the mutagenic role of Rad5 and indicate its tripartite contribution to DNA damage tolerance. © 2021 The Author(s)},
	keywords = {MUTAGENESIS; enzyme assay; DNA damage tolerance; Rad5; yeast genetics},
	year = {2022},
	eissn = {1089-8638},
	orcid-numbers = {Kiss, Ernő/0000-0002-7344-1750}
}

@article{MTMT:32101773,
	title = {BC-Monitor: Towards a Routinely Accessible Circulating Tumor DNA-Based Tool for Real-Time Monitoring Breast Cancer Progression and Treatment Effectiveness},
	url = {https://m2.mtmt.hu/api/publication/32101773},
	author = {Priskin, Katalin and Pólya, Sára and Pintér, Lajos and Jaksa, Gábor and Csányi, Bernadett and Enyedi, Márton Zsolt and Sági-Zsigmond, Eszter and Sükösd, Farkas and Oláh, Orsolya and Kelemen, Gyöngyi and Nikolényi, Alíz and Uhercsák, Gabriella and Sántha, Dóra and Dobi, Ágnes and Szilágyi, Éva and Valicsek, Erzsébet and Torday, László and Tóth, Rozália and Kahán, Zsuzsanna and Haracska, Lajos},
	doi = {10.3390/cancers13143489},
	journal-iso = {CANCERS},
	journal = {CANCERS},
	volume = {13},
	unique-id = {32101773},
	year = {2021},
	eissn = {2072-6694},
	orcid-numbers = {Oláh, Orsolya/0000-0002-5731-4030; Torday, László/0000-0002-2911-5499; Kahán, Zsuzsanna/0000-0002-5021-8775}
}

@article{MTMT:31268548,
	title = {Robust high-throughput assays to assess discrete steps in ubiquitination and related cascades},
	url = {https://m2.mtmt.hu/api/publication/31268548},
	author = {Fenteany, Gabriel and Gaur, Paras and Sharma, Gaurav and Pintér, Lajos and Kiss, Ernő and Haracska, Lajos},
	doi = {10.1186/s12860-020-00262-5},
	journal-iso = {BMC MOL CELL BIOL},
	journal = {BMC MOLECULAR AND CELL BIOLOGY},
	volume = {21},
	unique-id = {31268548},
	year = {2020},
	eissn = {2661-8850},
	orcid-numbers = {Fenteany, Gabriel/0000-0001-7407-2195; Kiss, Ernő/0000-0002-7344-1750}
}

@article{MTMT:30938381,
	title = {Keringő tumor DNS vizsgálat neoadjuváns kezelésben részesülő, illetve metasztatikus emlőrákos betegnél – kezdeti tapasztalataink},
	url = {https://m2.mtmt.hu/api/publication/30938381},
	author = {Kelemen, Gyöngyi and Tóth, R and Kószó, Renáta Lilla and Nikolényi, Alíz and Uhercsák, Gabriella and Sántha, Dóra and Valicsek, Erzsébet and Szilágyi, Éva and Torday, László and Pepó, J and Dobi, Ágnes and Priskin, Katalin and Pintér, Lajos and Pólya, Sára Erzsébet and Haracska, Lajos and Sükösd, Farkas and Kahán, Zsuzsanna},
	journal-iso = {MAGYAR ONKOLÓGIA},
	journal = {MAGYAR ONKOLÓGIA},
	volume = {63},
	unique-id = {30938381},
	issn = {0025-0244},
	year = {2019},
	eissn = {2060-0399},
	pages = {33-33},
	orcid-numbers = {Kószó, Renáta Lilla/0000-0002-1958-7839; Torday, László/0000-0002-2911-5499; Kahán, Zsuzsanna/0000-0002-5021-8775}
}

@article{MTMT:30846863,
	title = {Folyékony biopszia a klinikai onkológiában – a precíziós orvoslás vonalvezetője},
	url = {https://m2.mtmt.hu/api/publication/30846863},
	author = {Priskin, Katalin and Pintér, Lajos and Jaksa, Gábor and Pólya, Sára and Kahán, Zsuzsanna and Sükösd, Farkas and Haracska, Lajos},
	journal-iso = {KLINIKAI ONKOLÓGIA},
	journal = {KLINIKAI ONKOLÓGIA},
	volume = {6},
	unique-id = {30846863},
	issn = {2064-5058},
	year = {2019},
	pages = {65-72},
	orcid-numbers = {Kahán, Zsuzsanna/0000-0002-5021-8775}
}

@CONFERENCE{MTMT:30801735,
	title = {Keringő tumor DNS vizsgálat neoadjuváns kezelésben részesülő, illetve metasztatikus emlőrákos betegeknél – kezdeti tapasztalataink},
	url = {https://m2.mtmt.hu/api/publication/30801735},
	author = {Kelemen, Gyöngyi and Tóth, Rozália and Kószó, Renáta Lilla and Nikolényi, Alíz and Uhercsák, Gabriella and Sántha, Dóra and Valicsek, Erzsébet and Szilágyi, Éva and Torday, László and Pepó, Judit and Dobi, Ágnes and Priskin, Katalin and Pintér, Lajos and Pólya, Sára Erzsébet and Haracska, Lajos and Sükösd, Farkas and Kahán, Zsuzsanna},
	booktitle = {VIII. Szegedi Emlőrák Szimpózium},
	unique-id = {30801735},
	year = {2019},
	pages = {47-48},
	orcid-numbers = {Kószó, Renáta Lilla/0000-0002-1958-7839; Torday, László/0000-0002-2911-5499; Kahán, Zsuzsanna/0000-0002-5021-8775}
}

@article{MTMT:3166555,
	title = {DNA-dependent protease activity of human Spartan facilitates replication of DNA-protein crosslink-containing DNA.},
	url = {https://m2.mtmt.hu/api/publication/3166555},
	author = {Mórocz, Mónika and Zsigmond, Eszter and Tóth, Róbert and Enyedi, Márton Zsolt and Pintér, Lajos and Haracska, Lajos},
	doi = {10.1093/nar/gkw1315},
	journal-iso = {NUCLEIC ACIDS RES},
	journal = {NUCLEIC ACIDS RESEARCH},
	volume = {45},
	unique-id = {3166555},
	issn = {0305-1048},
	abstract = {Mutations in SPARTAN are associated with early onset hepatocellular carcinoma and progeroid features. A regulatory function of Spartan has been implicated in DNA damage tolerance pathways such as translesion synthesis, but the exact function of the protein remained unclear. Here, we reveal the role of human Spartan in facilitating replication of DNA-protein crosslink-containing DNA. We found that purified Spartan has a DNA-dependent protease activity degrading certain proteins bound to DNA. In concert, Spartan is required for direct DPC removal in vivo; we also show that the protease Spartan facilitates repair of formaldehyde-induced DNA-protein crosslinks in later phases of replication using the bromodeoxyuridin (BrdU) comet assay. Moreover, DNA fibre assay indicates that formaldehyde-induced replication stress dramatically decreases the speed of replication fork movement in Spartan-deficient cells, which accumulate in the G2/M cell cycle phase. Finally, epistasis analysis mapped these Spartan functions to the RAD6-RAD18 DNA damage tolerance pathway. Our results reveal that Spartan facilitates replication of DNA-protein crosslink-containing DNA enzymatically, as a protease, which may explain its role in preventing carcinogenesis and aging.},
	year = {2017},
	eissn = {1362-4962},
	pages = {3172-3188}
}