@CONFERENCE{MTMT:34395722,
	title = {A fel nem ismert hypoglykaemia gyakoriságának vizsgálata a sport szerepének tükrében},
	url = {https://m2.mtmt.hu/api/publication/34395722},
	author = {Várkonyi, Ákos and Kupai, Krisztina and Várkonyi, Tamás and Tokodi, Margaréta},
	booktitle = {IV. Leisure Tudományos Konferencia},
	unique-id = {34395722},
	year = {2024},
	pages = {18-19},
	orcid-numbers = {Kupai, Krisztina/0000-0002-0644-1718; Várkonyi, Tamás/0000-0001-6833-3563; Tokodi, Margaréta/0000-0002-0685-2904}
}

@misc{MTMT:34132116,
	title = {Dezmopresszin szerepe sinus petrosus inferiorok szelektív katéterezése Cushing kórban: endokrinológiai és idegsebészeti kooperáció},
	url = {https://m2.mtmt.hu/api/publication/34132116},
	author = {Kupai, Krisztina and Németh, T and Hausinger, Péter and Pósa, Anikó and Barzó, P and Valkusz, Zsuzsanna},
	unique-id = {34132116},
	year = {2023},
	orcid-numbers = {Kupai, Krisztina/0000-0002-0644-1718; Pósa, Anikó/0000-0003-2167-2888; Valkusz, Zsuzsanna/0000-0003-1928-6160}
}

@article{MTMT:33856409,
	title = {Paclitaxel Protects against Isoproterenol-Induced Damage in Rat Myocardium: Its Heme-Oxygenase Mediated Role in Cardiovascular Research},
	url = {https://m2.mtmt.hu/api/publication/33856409},
	author = {Matusovits, Danica and Murlasits, Zsolt and Kupai, Krisztina and Baráth, Zoltán Lajos and Hsu, Linkang and Osváth, Péter and Szűcs, Miklós and Priksz, Dániel and Juhász, Béla and Radák, Zsolt and Várkonyi, Tamás and Pávó, Imre and Pósa, Anikó},
	doi = {10.3390/antiox12051129},
	journal-iso = {ANTIOXIDANTS-BASEL},
	journal = {ANTIOXIDANTS},
	volume = {12},
	unique-id = {33856409},
	abstract = {(1) Background: In cardiovascular applications, paclitaxel inhibits smooth muscle cell proliferation and migration and significantly reduces the occurrence of restenosis and target lesion revascularization. However, the cellular effects of paclitaxel in the myocardium are not well understood; (2) Methods: Wistar rats were divided into four groups: control (CTRL), isoproterenol (ISO) treated (1 mg/kg) and two groups treated with paclitaxel (PAC), which was administrated (10 mg/kg/day) for 5 days by gavage/per os alone or in combination (ISO + PAC) 3 weeks after ISO treatment. Ventricular tissue was harvested 24 h later for measurements of heme oxygenase (HO-1), reduced glutathione (GSH), oxidized glutathione (GSSG), superoxide dismutase (SOD), NF-κB, TNF-α and myeloperoxidase (MPO); (3) Results: HO-1 protein concentration, HO-1 activity, SOD protein concentration and total glutathione significantly decreased in response to ISO treatment. When PAC was administered in conjunction with ISO, HO-1, SOD concentration and total glutathione were not different from control levels. MPO activity, NF-κB concentration and TNF-α protein concentration were significantly increased in the ISO-only group, while the levels of these molecules were restored when PAC was co-administered; (4) Conclusions: Oral administration of PAC can maintain the expression of important antioxidants, anti-inflammatory molecules, HO-1, SOD and GSH, and suppress the production of TNF-α, MPO and NF-κB, which are involved in myocardial damage. The principal component of this cellular defense seems to be the expression of HO-1.},
	year = {2023},
	eissn = {2076-3921},
	orcid-numbers = {Murlasits, Zsolt/0000-0003-4101-3417; Kupai, Krisztina/0000-0002-0644-1718; Baráth, Zoltán Lajos/0000-0003-0636-6313; Hsu, Linkang/0009-0001-2220-1562; Szűcs, Miklós/0000-0002-8606-996X; Radák, Zsolt/0000-0003-1297-6804; Várkonyi, Tamás/0000-0001-6833-3563; Pósa, Anikó/0000-0003-2167-2888}
}

@article{MTMT:33805049,
	title = {A komplex metabolikus állapot lehetséges szerepének vizsgálata az autonóm idegrendszeri működészavar kialakulásában 1-es típusú diabéteszben [Assessment of the role of the complex metabolic control in the development of autonomic dysfunction in type 1 diabetic patients]},
	url = {https://m2.mtmt.hu/api/publication/33805049},
	author = {Bordács, Barbara Anikó and Kupai, Krisztina and Valkusz, Zsuzsanna and Jost, K and Várkonyi, Ákos and Nyiraty, Szabolcs and Lengyel, Csaba Attila and Kempler, Péter and Várkonyi, Tamás},
	journal-iso = {DIABETOLOGIA HUNGARICA},
	journal = {DIABETOLOGIA HUNGARICA},
	volume = {31},
	unique-id = {33805049},
	issn = {1217-372X},
	year = {2023},
	eissn = {2560-0168},
	pages = {6-7},
	orcid-numbers = {Kupai, Krisztina/0000-0002-0644-1718; Valkusz, Zsuzsanna/0000-0003-1928-6160; Lengyel, Csaba Attila/0000-0002-0434-0067; Kempler, Péter/0000-0002-6072-8832; Várkonyi, Tamás/0000-0001-6833-3563}
}

@article{MTMT:33316600,
	title = {Role of physical activity and cardiorespiratory fitness in metabolically healthy obesity: a narrative review},
	url = {https://m2.mtmt.hu/api/publication/33316600},
	author = {Murlasits, Zsolt and Kupai, Krisztina and Kneffel, Zsuzsanna},
	doi = {10.1136/bmjsem-2022-001458},
	journal-iso = {BMJ OPEN SPORT EXCERC MED},
	journal = {BMJ OPEN SPORT & EXCERCISE MEDICINE},
	volume = {8},
	unique-id = {33316600},
	abstract = {Obesity has been associated with a multitude of metabolic disorders, often clustering with risk factors of cardiovascular disease and type 2 diabetes mellitus, hypertension, dyslipidaemia. Overall, obesity is a worldwide, growing health concern. However, a subgroup of obese individuals with a low burden of metabolic abnormalities have been identified and described as metabolically healthy obese (MHO). Whether the MHO phenotype is protective against obesity-related metabolic disorders in the long-term is presently unclear, and current research examining the potential transition has yielded inconsistent results. In this current narrative review, we aim to provide insights on the role of physical activity (PA) and cardiorespiratory fitness (CRF) in MHO. Lifestyle factors such as PA and CRF may influence the MHO phenotype. Limited studies have characterised energy expenditure and CRF in MHO and metabolically unhealthy obese. However, higher levels of PA, less sedentary behaviour and higher CRF have been observed in MHO individuals. Considering the multiple benefits of PA, it is high time to advocate this lifestyle change beyond its influence on energy balance in a weight loss programme to improve cardiovascular and metabolic risk factors irrespective of body weight and fat mass changes. Improved CRF via increased PA, especially exercise participation, while avoiding weight gain is not only a realistic goal, but should be the primary intervention for MHO populations to prevent the transition to an abnormal metabolic state.},
	year = {2022},
	eissn = {2055-7647},
	orcid-numbers = {Murlasits, Zsolt/0000-0003-4101-3417; Kupai, Krisztina/0000-0002-0644-1718}
}

@misc{MTMT:33116012,
	title = {Anti-inflammatory effect of hydrogen sulfide is mediated via the activation of Prdx6 in TNBS-induced rat colitis},
	url = {https://m2.mtmt.hu/api/publication/33116012},
	author = {Török, Szilvia and Almási, Nikoletta and Baráth, D and Pósa, Anikó and Kupai, Krisztina and Varga, Csaba},
	unique-id = {33116012},
	year = {2022},
	orcid-numbers = {Almási, Nikoletta/0000-0002-7371-5272; Pósa, Anikó/0000-0003-2167-2888; Kupai, Krisztina/0000-0002-0644-1718; Varga, Csaba/0000-0002-2678-665X}
}

@misc{MTMT:33116005,
	title = {The protective effect of voluntary exercise is mediated by the inhibition of NETosis and upregulation of Prdx6 in TNBS-induced rat colitis},
	url = {https://m2.mtmt.hu/api/publication/33116005},
	author = {Almási, Nikoletta and Török, Szilvia and Al-Awar, Amin and Veszelka, Médea and Baráth, D and Pósa, Anikó and Kupai, Krisztina and Varga, Csaba},
	unique-id = {33116005},
	year = {2022},
	orcid-numbers = {Almási, Nikoletta/0000-0002-7371-5272; Pósa, Anikó/0000-0003-2167-2888; Kupai, Krisztina/0000-0002-0644-1718; Varga, Csaba/0000-0002-2678-665X}
}

@article{MTMT:33089323,
	title = {Fehérjék poszttranszlációs módosításának szerepe 1-es típusú diabetes mellitusban [ Role of post-translational modifications of proteins in experimental type 1 diabetes]},
	url = {https://m2.mtmt.hu/api/publication/33089323},
	author = {Kupai, Krisztina and Török, Szilvia and Várkonyi, Ákos and Csonka, Á and Almási, Nikoletta and Várkonyi, Tamás and Lengyel, Csaba Attila and Valkusz, Zsuzsanna and Pósa, Anikó and Varga, Csaba},
	journal-iso = {DIABETOLOGIA HUNGARICA},
	journal = {DIABETOLOGIA HUNGARICA},
	volume = {30},
	unique-id = {33089323},
	issn = {1217-372X},
	year = {2022},
	eissn = {2560-0168},
	pages = {62-63},
	orcid-numbers = {Kupai, Krisztina/0000-0002-0644-1718; Almási, Nikoletta/0000-0002-7371-5272; Várkonyi, Tamás/0000-0001-6833-3563; Lengyel, Csaba Attila/0000-0002-0434-0067; Valkusz, Zsuzsanna/0000-0003-1928-6160; Pósa, Anikó/0000-0003-2167-2888; Varga, Csaba/0000-0002-2678-665X}
}

@article{MTMT:33075619,
	title = {Autonomic and sensory neuropathy in typee 1 diabetic patients with different disease durations},
	url = {https://m2.mtmt.hu/api/publication/33075619},
	author = {Várkonyi, Tamás and Nyiraty, Szabolcs and Tóth, Bettina and Pesei, F and Kupai, Krisztina and Vágvölgyi, Anna and Orosz, Andrea and Lengyel, Csaba Attila and Kempler, Péter},
	journal-iso = {DIABETES STOFFWECH H},
	journal = {DIABETES STOFFWECHSEL UND HERZ},
	volume = {31},
	unique-id = {33075619},
	issn = {1861-7603},
	year = {2022},
	eissn = {1861-7603},
	pages = {245-245},
	orcid-numbers = {Várkonyi, Tamás/0000-0001-6833-3563; Kupai, Krisztina/0000-0002-0644-1718; Vágvölgyi, Anna/0000-0002-8810-700X; Lengyel, Csaba Attila/0000-0002-0434-0067; Kempler, Péter/0000-0002-6072-8832}
}

@article{MTMT:33056290,
	title = {Recent Progress in the Diagnosis and Management of Type 2 Diabetes Mellitus in the Era of COVID-19 and Single Cell Multi-Omics Technologies},
	url = {https://m2.mtmt.hu/api/publication/33056290},
	author = {Kupai, Krisztina and Várkonyi, Tamás and Török, Szilvia and Gáti, Viktória and Czimmerer, Zsolt and Puskás, László and Szebeni, Gábor},
	doi = {10.3390/life12081205},
	journal-iso = {LIFE-BASEL},
	journal = {LIFE-BASEL},
	volume = {12},
	unique-id = {33056290},
	abstract = {Type 2 diabetes mellitus (T2DM) is one of the world’s leading causes of death and life-threatening conditions. Therefore, we review the complex vicious circle of causes responsible for T2DM and risk factors such as the western diet, obesity, genetic predisposition, environmental factors, and SARS-CoV-2 infection. The prevalence and economic burden of T2DM on societal and healthcare systems are dissected. Recent progress on the diagnosis and clinical management of T2DM, including both non-pharmacological and latest pharmacological treatment regimens, are summarized. The treatment of T2DM is becoming more complex as new medications are approved. This review is focused on the non-insulin treatments of T2DM to reach optimal therapy beyond glycemic management. We review experimental and clinical findings of SARS-CoV-2 risks that are attributable to T2DM patients. Finally, we shed light on the recent single-cell-based technologies and multi-omics approaches that have reached breakthroughs in the understanding of the pathomechanism of T2DM.},
	keywords = {Inflammation; OBESITY; Insulin Resistance; type 2 diabetes mellitus; CVD risk; COVID-19},
	year = {2022},
	eissn = {2075-1729},
	orcid-numbers = {Kupai, Krisztina/0000-0002-0644-1718; Várkonyi, Tamás/0000-0001-6833-3563; Szebeni, Gábor/0000-0002-6998-5632}
}