@article{MTMT:34796471, title = {Favipiravir does not improve viral clearance in mild to moderate COVID-19 – a systematic review and meta-analysis of randomized controlled trials}, url = {https://m2.mtmt.hu/api/publication/34796471}, author = {Bahar, Muhammad Akbar and Kusuma, Ikhwan Yuda and Visnyovszki, Ádám and Matuz, Mária and Benkő, Ria and Ferenci, Tamás and Szabó, Bálint Gergely and Hajdú, Edit and Pető, Zoltán and Csupor, Dezső}, doi = {10.1016/j.heliyon.2024.e29808}, journal-iso = {HELIYON}, journal = {HELIYON}, volume = {10}, unique-id = {34796471}, keywords = {[Meta-analysis]}, year = {2024}, eissn = {2405-8440}, orcid-numbers = {Matuz, Mária/0000-0002-7877-2399; Benkő, Ria/0000-0002-8009-8962; Ferenci, Tamás/0000-0001-6791-3080; Szabó, Bálint Gergely/0000-0003-1775-1356; Csupor, Dezső/0000-0002-4088-3333} } @article{MTMT:34721808, title = {Correlation between Stenotrophomonas maltophilia incidence and systemic antibiotic use: A 10-year retrospective, observational study in Hungary}, url = {https://m2.mtmt.hu/api/publication/34721808}, author = {Gajdács, Márió and Matuz, Mária and Benkő, Ria and Pető, Zoltán and Hajdú, Edit}, doi = {10.1556/1886.2024.00022}, journal-iso = {EUR J MICROBIOL IMMU}, journal = {EUROPEAN JOURNAL OF MICROBIOLOGY AND IMMUNOLOGY}, unique-id = {34721808}, issn = {2062-509X}, abstract = {Extensive use of carbapenems may lead to selection pressure for Stenotrophomonas maltophilia (SM) in hospital environments. The aim of our study was to assess the possible association between systemic antibiotic use and the incidence of SM. A retrospective, observational study was carried out in a tertiary-care hospital in Hungary, between January 1st 2010 and December 31st 2019. Incidence-density for SM and SM resistant to trimethoprim-sulfamethoxazole (SXT) was standardized for 1000 patient-days, while systemic antibiotic use was expressed as defined daily doses (DDDs) per 100 patient-days. Mean incidence density for SM infections was 0.42/1000 patient-days; 11.08% were were resistant to SXT, the mean incidence density for SXT-resistant SM was 0.047/1000 patient-days. Consumption rate for colistin, glycopeptides and carbapenems increased by 258.82, 278.94 and 372.72% from 2010 to 2019, respectively. Strong and significant positive correlations were observed with the consumption of carbapenems (r: 0.8759; P < 0.001 and r: 0.8968; P < 0.001), SXT (r: 0.7552; P = 0.011 and r: 0.7004; P = 0.024), and glycopeptides (r: 0.7542; P = 0.012 and r: 0.8138; P < 0.001) with SM and SXT-resistant SM incidence-density/1000 patient-days, respectively. Implementation of institutional carbapenem-sparing strategies are critical in preserving these life-saving drugs, and may affect the microbial spectrum of infections in clinical settings.}, year = {2024}, eissn = {2062-8633}, orcid-numbers = {Gajdács, Márió/0000-0003-1270-0365; Matuz, Mária/0000-0002-7877-2399; Benkő, Ria/0000-0002-8009-8962} } @article{MTMT:34657209, title = {Tixagevimab-cilgavimab (AZD7442) for the treatment of patients hospitalized with COVID-19 (DisCoVeRy). a phase 3, randomized, double-blind, placebo-controlled trial.}, url = {https://m2.mtmt.hu/api/publication/34657209}, author = {Hites, Maya and Massonnaud, Clément R and Jamard, Simon and Goehringer, François and Danion, François and Reignier, Jean and de Castro, Nathalie and Garot, Denis and Lapique, Eva Larranaga and Lacombe, Karine and Tolsma, Violaine and Faure, Emmanuel and Malvy, Denis and Staub, Thérèse and Courjon, Johan and Cazenave-Roblot, France and Riise, Anne Ma Dyrhol and Leturnier, Paul and Martin-Blondel, Guillaume and Roger, Claire and Akinosoglou, Karolina and Moing, Vincent Le and Piroth, Lionel and Sellier, Pierre and Lescure, Xavier and Trøseid, Marius and Clevenbergh, Philippe and Dalgard, Olav and Gallien, Sébastien and Gousseff, Marie and Loubet, Paul and Vardon-Bounes, Fanny and Visée, Clotilde and Belkhir, Leila and Botelho-Nevers, Élisabeth and Cabié, André and Kotanidou, Anastasia and Lanternier, Fanny and Rouveix-Nordon, Elisabeth and Silva, Susana and Thiery, Guillaume and Poignard, Pascal and Carcelain, Guislaine and Diallo, Alpha and Mercier, Noémie and Terzic, Vida and Bouscambert-Duchamp, Maude and Gaymard, Alexandre and Trabaud, Mary-Anne and Destras, Grégory and Josset, Laurence and Belhadi, Drifa and Billard, Nicolas and Guedj, Jérémie and Han, Thi-Hong-Lien and Couffin-Cadiergues, Sandrine and Dechanet, Aline and Delmas, Christelle and Esperou, Hélène and Fougerou-Leurent, Claire and Mestre, Soizic Le and Métois, Anabelle and Noret, Marion and Bally, Isabelle and Dergan-Dylon, Sebastián and Tubiana, Sarah and Kalif, Ouifiya and Bergaud, Nathalie and Leveau, Benjamin and Eustace, Joe and Greil, Richard and Hajdú, Edit and Halanova, Monika and Paiva, Jose-Artur and Piekarska, Anna and Baño, Jesus Rodriguez and Tonby, Kristian and Trojánek, Milan and Tsiodras, Sotirios and Unal, Serhat and Burdet, Charles and Costagliola, Dominique and Yazdanpanah, Yazdan and Peiffer-Smadja, Nathan and Mentré, France and Ader, Florence}, doi = {10.1016/j.jinf.2024.106120}, journal-iso = {J INFECTION}, journal = {JOURNAL OF INFECTION}, volume = {88}, unique-id = {34657209}, issn = {0163-4453}, year = {2024}, eissn = {1532-2742} } @article{MTMT:34532941, title = {Hospital Antibiotic Consumption before and during the COVID-19 Pandemic in Hungary}, url = {https://m2.mtmt.hu/api/publication/34532941}, author = {Ruzsa, Roxána and Benkő, Ria and Hambalek, Helga and Papfalvi, Erika Piroska and Csupor, Dezső and Nacsa, Róbert and Csatordai, Márta and Soós, Gyöngyvér and Hajdú, Edit and Matuz, Mária}, doi = {10.3390/antibiotics13010102}, journal-iso = {ANTIBIOTICS-BASEL}, journal = {ANTIBIOTICS}, volume = {13}, unique-id = {34532941}, abstract = {The aim of this study was to assess antibiotic use in the Hungarian hospital care sector during and before the pandemic. Aggregated systemic antibiotic (ATC: J01) utilisation data were obtained for the 2010–2021 period. Classifications and calculations were performed according to the WHO ATC/DDD index and expressed as DDD per 1000 inhabitants and per day (DID), DDD per 100 patient-days (DHPD) and DDD/discharge. A linear regression (trend analysis) was performed for the pre-COVID years (2010–2019) and a prediction interval was set up to assess whether the pandemic years’ observed utilisation fit in. Antibiotic utilisation was constant in DID before and during the pandemic (2019: 1.16; 2020: 1.21), while we observed a substantial increase in antibiotic use when expressed in DDD per 100 patient-days (2019: 23.3, 2020: 32.2) or DDD/discharge (2019: 1.83, 2020: 2.45). The observed utilisation level of penicillin combinations; first-, third- and fourth-generation cephalosporins; carbapenems; glycopeptides; nitroimidazoles and macrolides exceeded the predicted utilisation values in both pandemic years. Before the pandemic, co-amoxiclav headed the top list of antibiotic use, while during the pandemic, ceftriaxone became the most widely used antibiotic. Azithromycin moved up substantially on the top list of antibiotic use, with a 397% increase (2019: 0.45; 2020: 2.24 DHPD) in use. In summary, the pandemic had a major impact on the scale and pattern of hospital antibiotic use in Hungary.}, year = {2024}, eissn = {2079-6382}, orcid-numbers = {Benkő, Ria/0000-0002-8009-8962; Csupor, Dezső/0000-0002-4088-3333; Matuz, Mária/0000-0002-7877-2399} } @CONFERENCE{MTMT:34500723, title = {Stenotrophomonas maltophilia epidemiológiája és az antibiotikum-fogyasztás közötti összefüggések: 10-éves korrelációs vizsgálat}, url = {https://m2.mtmt.hu/api/publication/34500723}, author = {Gajdács, Márió and Benkő, Ria and Matuz, Mária and Bodó, Gabriella and Pető, Zoltán and Hajdú, Edit}, booktitle = {XV. Fiatal Higiénikusok Fóruma: Program és összefoglalók}, unique-id = {34500723}, year = {2023}, pages = {12-12}, orcid-numbers = {Gajdács, Márió/0000-0003-1270-0365; Benkő, Ria/0000-0002-8009-8962; Matuz, Mária/0000-0002-7877-2399} } @article{MTMT:34398415, title = {Kórházi antibiotikum alkalmazás kórházakban: volt COVID hatás hazánkban? [Hospital care antibiotic use in hungary: was there a COVID effect?]}, url = {https://m2.mtmt.hu/api/publication/34398415}, author = {Ruzsa, Roxána and Benkő, Ria and Hambalek, Helga and Csupor, Dezső and Csatordai, Márta and Soós, Gyöngyvér and Papfalvi, Erika Piroska and Kusuma, Ikhwan Yuda and Hajdú, Edit and Matuz, Mária}, journal-iso = {ACTA PHARM HUNG}, journal = {ACTA PHARMACEUTICA HUNGARICA}, volume = {93}, unique-id = {34398415}, issn = {0001-6659}, year = {2023}, eissn = {1587-1495}, pages = {S69-S70}, orcid-numbers = {Benkő, Ria/0000-0002-8009-8962; Csupor, Dezső/0000-0002-4088-3333; Matuz, Mária/0000-0002-7877-2399} } @article{MTMT:34398369, title = {Súlyos disszeminált acanthamoeba fertőzés: esettanulmány a klinikai gyógyszerész szemével [Severe disseminated acanthamoeba infection: case study from a clinical pharmacist viewpoint]}, url = {https://m2.mtmt.hu/api/publication/34398369}, author = {Hambalek, Helga and Varga, Erika and Csoma, Zsanett and Szolnoky, Győző and Szadai, Leticia and Honfi, Vivien and Soós, Gyöngyvér and Hajdú, Edit and Matuz, Mária and Benkő, Ria}, journal-iso = {ACTA PHARM HUNG}, journal = {ACTA PHARMACEUTICA HUNGARICA}, volume = {93}, unique-id = {34398369}, issn = {0001-6659}, year = {2023}, eissn = {1587-1495}, pages = {S48-S49}, orcid-numbers = {Csoma, Zsanett/0000-0003-0376-9061; Szolnoky, Győző/0000-0002-5391-4426; Matuz, Mária/0000-0002-7877-2399; Benkő, Ria/0000-0002-8009-8962} } @article{MTMT:34398357, title = {Ambuláns antibiotikum alkalmazás: volt – e a pandémiának hatása? [Ambulatory care antibiotic use in Hungary: was there a pandemic effect?]}, url = {https://m2.mtmt.hu/api/publication/34398357}, author = {Hambalek, Helga and Matuz, Mária and Ruzsa, Roxána and Engi, Zsófia and Csupor, Dezső and Doró, Péter and Soós, Gyöngyvér and Visnyovszki, Ádám and Hajdú, Edit and Benkő, Ria}, journal-iso = {ACTA PHARM HUNG}, journal = {ACTA PHARMACEUTICA HUNGARICA}, volume = {93}, unique-id = {34398357}, issn = {0001-6659}, year = {2023}, eissn = {1587-1495}, pages = {S47-S48}, orcid-numbers = {Matuz, Mária/0000-0002-7877-2399; Csupor, Dezső/0000-0002-4088-3333; Doró, Péter/0000-0001-7784-6010; Benkő, Ria/0000-0002-8009-8962} } @article{MTMT:34392952, title = {Antibiotikum stewardship a sürgősségi osztályon [Antibiotic stewardship in the emergency department]}, url = {https://m2.mtmt.hu/api/publication/34392952}, author = {Benkő, Ria and Papfalvi, Erika Piroska and Nacsa, Róbert and Matuz, Mária and Ruzsa, Roxána and Hambalek, Helga and Hajdú, Edit and Pető, Zoltán and Erdélyi, Péter and Soós, Gyöngyvér}, journal-iso = {ACTA PHARM HUNG}, journal = {ACTA PHARMACEUTICA HUNGARICA}, volume = {93}, unique-id = {34392952}, issn = {0001-6659}, year = {2023}, eissn = {1587-1495}, pages = {S34-S35}, orcid-numbers = {Benkő, Ria/0000-0002-8009-8962; Matuz, Mária/0000-0002-7877-2399} } @CONFERENCE{MTMT:34194554, title = {Retrospektív 5 éves vizsgálat: a húgyúti szepszist okozó multirezisztens baktériumok előfordulása és trendje}, url = {https://m2.mtmt.hu/api/publication/34194554}, author = {Dudás, Gábor and Orosz, László and Matuz, Mária and Benkő, Ria and Hajdú, Edit and Visnyovszki, Ádám}, booktitle = {A Magyar Infektológiai és Klinikai Mikrobiológiai Társaság 50. kongresszusa}, unique-id = {34194554}, year = {2023}, pages = {53-53}, orcid-numbers = {Matuz, Mária/0000-0002-7877-2399; Benkő, Ria/0000-0002-8009-8962} }