TY - JOUR AU - Nochta-Kazsoki, Adrienn Katalin AU - Németh, Krisztina AU - Visnovitz, Tamás AU - Lenzinger, Dorina AU - Buzás, Edit Irén AU - Zelkó, Romána TI - Formulation and characterization of nanofibrous scaffolds incorporating extracellular vesicles loaded with curcumin JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 14 PY - 2024 PG - 11 SN - 2045-2322 DO - 10.1038/s41598-024-79277-3 UR - https://m2.mtmt.hu/api/publication/35526600 ID - 35526600 N1 - Adrienn Kazsoki and Krisztina Németh authors contributed equally LA - English DB - MTMT ER - TY - CONF AU - Zelenyánszki, Helga AU - Klencsár, Zoltán AU - Visnovitz, Tamás AU - Kolbert, Zsuzsanna AU - Solti, Ádám TI - Nitric oxide accumulates under iron deficiency in chloroplasts T2 - 9th Plant Nitric Oxide International Meeting (PNO9) C1 - New Delhi PY - 2024 SP - 7 EP - 7 PG - 1 UR - https://m2.mtmt.hu/api/publication/35172786 ID - 35172786 AB - Iron (Fe) is an essential cofactor of multiple enzymes, but to avoid its hazardous effects on oxidative stress, signalling of the Fe status, especially in plant cells organelles is essential, although hardly known. Since 80–90% of Fe in the mesophyll cells is targeted to the chloroplasts to operate the photosynthetic apparatus, the control over plastidial Fe status has prime importance. Sensing the cytoplasmic Fe is based on hemerythrin motif-containing E3 ubiquitin ligases that are negative regulators of Fe deficiency responses. Indeed, no mechanisms are described that monitor the Fe status of the organelles. In vitro chloroplast Fe uptake (Solti et al., 2012; Müller et al. 2019) and ferric chelate reductase enzyme studies (Solti et al. 2014; Sági-Kazár et al. 2021) suggests that Fe in the chloroplasts has a feedback regulatory effect on the affinity of the plastidial Fe acquisition machinery. Nitric oxide (NO) is long known to regulate Fe uptake of roots, but also generated in chloroplasts under increasing Fe availability. It is involved in post translation modification of proteins that directly affect the function of those. Since the synthesis and accumulation of NO in chloroplasts has not been confirmed so far, we aimed here to detect and quantify NO in response to altered Fe nutrition chloroplasts. Sugar beet (Beta vulgaris cv. Orbis) model was grown on Fe(III)-EDTA source. Fe deficiency (Fe-def) was achieved with a complete depletion of Fe in the four-leaf stage. Mesophyll cell protoplasts and chloroplasts were isolated. Abundance of the NO signal in the protoplast population and the subcellular NO locations in the protoplasts were analysed applying DAF-FM diacetate in fluorescence activated cell sorting and confocal microscopy, respectively. The proportion of DAF-FM positive protoplasts significantly increased under iron deficiency, together with a higher apparent DAF-FM signal intensity in the protoplasts. Applying BioXol membrane staining of the chloroplast envelopes, chloroplast stroma origin of the DAF-FM signal was approved. DAF-FM signal of isolated chloroplasts was analysed by epifluorescent microscope, also indicating an increased ratio and pixel density of DAF-FM positive chloroplasts under Fe-def compared to the control. Electron paramagnetic resonance (EPR) spectroscopy based semiquantitative NO determination, applying N-methyl-D-glucamine dithiocarbamate spin trap and 150 K environment indicated a concentration of NO in the Fe-def chloroplasts around the lower detection limit, that of attomol NO chloroplast-1 dimension. NO in the control chloroplasts remained below the detection limit. Tyr nitration pattern detected by anti-nitro-Tyr immunoblotting of total chloroplast protein showed no significant changes in the Tyr nitration status indicating that nitrosative stress level has not increased significantly. This work was supported by the grant financed by the National Research, Development and Innovation Office, Hungary (NKFIH K-135607). Á.S. was also supported by the Bolyai János Research Scholarship of the Hungarian Academy of Sciences (BO/00113/23/8). References Müller et al. (2019) Planta 249:751. Sági-Kazár et al. (2021) Front Plant Sci 12:748. Solti et al. (2014) New Phytol 202:920. Solti et al. (2012) Plant Physiol Biochem 52:91 LA - English DB - MTMT ER - TY - JOUR AU - Balassa, Kinga AU - Balassa, György AU - Almási, Asztéria AU - Visnovitz, Tamás AU - Rudnóy, Szabolcs TI - Detection of exogenous siRNA inside sweet corn bundle sheath cells and the RNAi dynamics in the early stage of Maize dwarf mosaic virus infection. JF - PHYSIOLOGY AND MOLECULAR BIOLOGY OF PLANTS J2 - PHYSIOL MOL BIOL PLANTS VL - 30 PY - 2024 IS - 8 SP - 1265 EP - 1276 PG - 12 SN - 0971-5894 DO - 10.1007/s12298-024-01500-2 UR - https://m2.mtmt.hu/api/publication/35164265 ID - 35164265 LA - English DB - MTMT ER - TY - JOUR AU - György, Bernadett AU - Pálóczi, Krisztina AU - Balbisi, Mirjam AU - Turiák, Lilla AU - Drahos, László AU - Visnovitz, Tamás AU - Koltai, Erika AU - Radák, Zsolt TI - Effect of the 35 nm and 70 nm Size Exclusion Chromatography (SEC) Column and Plasma Storage Time on Separated Extracellular Vesicles JF - CURRENT ISSUES IN MOLECULAR BIOLOGY J2 - CURR ISSUES MOL BIOL VL - 46 PY - 2024 IS - 5 SP - 4337 EP - 4357 PG - 21 SN - 1467-3037 DO - 10.3390/cimb46050264 UR - https://m2.mtmt.hu/api/publication/34850199 ID - 34850199 N1 - Research Centre for Molecular Exercise Science, Hungarian University of Sport Science, Alkotás u. 42-48, Budapest, 1123, Hungary Department of Genetics, Cell and Immunobiology, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary Research Centre for Natural Sciences, Institute of Organic Chemistry, Magyar Tudósok Körútja 2, Budapest, 1117, Hungary Department of Plant Physiology and Molecular Plant Biology, ELTE Eötvös Loránd University, Pázmány Péter sétány 1/c, Budapest, 1117, Hungary Faculty of Sport Sciences, Waseda University, Tokorozawa 2-579-15, Japan Export Date: 17 June 2024 CODEN: CMBIF Correspondence Address: Radák, Z.; Research Centre for Molecular Exercise Science, Alkotás u. 42-48, Hungary; email: radak.zsolt@tf.hu AB - The technical difficulty of separating extracellular vesicles (EVs) from plasma proteins in human blood presents a significant hurdle in EV research, particularly during nano ultra-high-performance liquid chromatography–tandem mass spectrometric (UHPLC-MS/MS) analysis, where detecting “vesicular” proteins among abundant plasma proteins is challenging. Standardisation is a pressing issue in EV research, prompting collaborative global efforts to address it. While the MISEV guidelines offer valuable recommendations, unanswered questions remain, particularly regarding sample storage. We compared size exclusion chromatography (SEC) columns with pore sizes of 35 nm and 70 nm to identify fractions with minimal contaminating proteins and the highest concentration of small EVs (sEVs). Following column selection, we explored potential differences in the quality and quantity of sEVs isolated from platelet-free plasma (PFP) after long-term storage at −80 °C (>2.5 years) compared to freshly drawn blood. Our methodologically rigorous study indicates that prolonged storage, under correct storage and processing conditions, does not compromise sEV quality. Both columns effectively isolated vesicles, with the 70 nm column exhibiting a higher abundance of “vesicular” proteins. We propose a relatively rapid and moderately efficient protocol for obtaining a comparatively pure sEV fraction from plasma, facilitating sEV processing in clinical trials. LA - English DB - MTMT ER - TY - JOUR AU - Visnovitz, Tamás AU - Lenzinger, Dorina AU - Koncz, Anna AU - Vizi, Péter M AU - Bárkai, Tünde AU - Visnovitzné Dr Vukman, Krisztina AU - Galinsoga, Alicia AU - Németh, Krisztina AU - Fletcher, Kelsey AU - Komlósi, Zsolt AU - Lőrincz, Péter AU - Valcz, Gábor AU - Buzás, Edit Irén TI - A “torn bag mechanism” of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes) JF - ELIFE J2 - ELIFE VL - 13 PY - 2024 PG - 35 SN - 2050-084X DO - 10.7554/eLife.95828.1 UR - https://m2.mtmt.hu/api/publication/34720930 ID - 34720930 LA - English DB - MTMT ER - TY - GEN AU - Visnovitz, Tamás AU - Lenzinger, Dorina AU - Koncz, Anna AU - Vizi, Péter M AU - Bárkai, Tünde AU - Vukman, Krisztina V AU - Galinsoga, Alicia AU - Németh, Krisztina AU - Fletcher, Kelsey AU - Komlósi, Zsolt I TI - A “torn bag mechanism” of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes) PY - 2024 SP - 2024 UR - https://m2.mtmt.hu/api/publication/34692287 ID - 34692287 LA - English DB - MTMT ER - TY - JOUR AU - Welsh, Joshua A. AU - Goberdhan, Deborah C. I. AU - O'Driscoll, Lorraine AU - Buzás, Edit Irén AU - Blenkiron, Cherie AU - Bussolati, Benedetta AU - Cai, Houjian AU - Di Vizio, Dolores AU - Driedonks, Tom A. P. AU - Erdbrügger, Uta AU - Falcon‐Perez, Juan M. AU - Fu, Qing‐Ling AU - Hill, Andrew F. AU - Lenassi, Metka AU - Lim, Sai Kiang AU - Mahoney, Mỹ G. AU - Mohanty, Sujata AU - Möller, Andreas AU - Nieuwland, Rienk AU - Ochiya, Takahiro AU - Sahoo, Susmita AU - Torrecilhas, Ana C. AU - Zheng, Lei AU - Zijlstra, Andries AU - Abuelreich, Sarah AU - Bagabas, Reem AU - Bergese, Paolo AU - Bridges, Esther M. AU - Brucale, Marco AU - Burger, Dylan AU - Carney, Randy P. AU - Cocucci, Emanuele AU - Colombo, Federico AU - Crescitelli, Rossella AU - Hanser, Edveena AU - Harris, Adrian L. AU - Haughey, Norman J. AU - Hendrix, An AU - Ivanov, Alexander R. AU - Jovanovic‐Talisman, Tijana AU - Kruh‐Garcia, Nicole A. AU - Ku'ulei‐Lyn Faustino, Vroniqa AU - Kyburz, Diego AU - Lässer, Cecilia AU - Lennon, Kathleen M. AU - Lötvall, Jan AU - Maddox, Adam L. AU - Martens‐Uzunova, Elena S. AU - Mizenko, Rachel R. AU - Newman, Lauren A. AU - Ridolfi, Andrea AU - Rohde, Eva AU - Rojalin, Tatu AU - Rowland, Andrew AU - Saftics, Andras AU - Sandau, Ursula S. AU - Saugstad, Julie A. AU - Shekari, Faezeh AU - Swift, Simon AU - Ter‐Ovanesyan, Dmitry AU - Tosar, Juan P. AU - Useckaite, Zivile AU - Valle, Francesco AU - Varga, Zoltán AU - van der Pol, Edwin AU - van Herwijnen, Martijn J. C. AU - Wauben, Marca H. M. AU - Wehman, Ann M. AU - Williams, Sarah AU - Zendrini, Andrea AU - Zimmerman, Alan J. AU - Théry, Clotilde AU - Witwer, Kenneth W. ED - Sarah, Abuelreich / Collaborator ED - Samar, Ahmad / Collaborator ED - Dina, AK Ahmed / Collaborator ED - Sarah, H Ahmed / Collaborator ED - Elena, Aikawa / Collaborator ED - Naveed, Akbar / Collaborator ED - Kazunari, Akiyoshi / Collaborator ED - David, P Al-Adra / Collaborator ED - Maimonah, E Al-Masawa / Collaborator ED - Manuel, Albanese / Collaborator ED - Ainhoa, Alberro / Collaborator ED - María, José Alcaraz / Collaborator ED - Jen, Alexander-Brett / Collaborator ED - Kimberley, L Alexander / Collaborator ED - Nilufar, Ali / Collaborator ED - Faisal, J Alibhai / Collaborator ED - Susann, Allelein / Collaborator ED - Mark, C Allenby / Collaborator ED - Fausto, Almeida / Collaborator ED - Luis, Pereira de Almeida / Collaborator ED - Sameh, W Almousa / Collaborator ED - Nihal, Altan-Bonnet / Collaborator ED - Wanessa, F Altei / Collaborator ED - Gloria, Alvarez-Llamas / Collaborator ED - Cora, L Alvarez / Collaborator ED - Hyo, Jung An / Collaborator ED - Krishnan, Anand / Collaborator ED - Samir, EL Andaloussi / Collaborator ED - Johnathon, D Anderson / Collaborator ED - Ramaroson, Andriantsitohaina / Collaborator ED - Khairul, I Ansari / Collaborator ED - Achille, Anselmo / Collaborator ED - Anna, Antoniou / Collaborator ED - Farrukh, Aqil / Collaborator ED - Tanina, Arab / Collaborator ED - Fabienne, Archer / Collaborator ED - Syrine, Arif / Collaborator ED - David, A Armstrong / Collaborator ED - Onno, J Arntz / Collaborator ED - Pierre, Arsène / Collaborator ED - Luis, Arteaga-Blanco / Collaborator ED - Nandini, Asokan / Collaborator ED - Trude, Aspelin / Collaborator ED - Georgia, K Atkin-Smith / Collaborator ED - Dimitri, Aubert / Collaborator ED - Kanchana, K Ayyar / Collaborator ED - Maryam, Azlan / Collaborator ED - Ioannis, Azoidis / Collaborator ED - Anaïs, Bécot / Collaborator ED - Jean-Marie, Bach / Collaborator ED - Daniel, Bachurski / Collaborator ED - Seoyoon, Bae / Collaborator ED - Reem, Bagabas / Collaborator ED - Roger, Olofsson Bagge / Collaborator ED - Monika, Baj-Krzyworzeka / Collaborator ED - Leonora, Balaj / Collaborator ED - Carolina, Balbi / Collaborator ED - Bas, WM van Balkom / Collaborator ED - Abhijna, R Ballal / Collaborator ED - Afsareen, Bano / Collaborator ED - Sébastien, Banzet / Collaborator ED - Yonis, Bare / Collaborator ED - Lucio, Barile / Collaborator ED - Bahnisikha, Barman / Collaborator ED - Isabel, Barranco / Collaborator ED - Valeria, Barreca / Collaborator ED - Geneviève, Bart / Collaborator ED - Natasha, S Barteneva / Collaborator ED - Manuela, Basso / Collaborator ED - Mona, Batish / Collaborator ED - Natalie, R Bauer / Collaborator ED - Amy, A Baxter / Collaborator ED - Wilfried, W Bazié / Collaborator ED - Erica, Bazzan / Collaborator ED - Joel, EJ Beaumont / Collaborator ED - Mary, Bebawy / Collaborator ED - Maarten, P Bebelman / Collaborator ED - Apolonija, Bedina-Zavec / Collaborator ED - Danielle, J Beetler / Collaborator AU - Beke-Somfai, Tamás ED - Clémence, Belleannée / Collaborator ED - Birke, J Benedikter / Collaborator ED - Berglind, E Benediktsdóttir / Collaborator ED - Anna, C Berardi / Collaborator ED - Mathilde, Bergamelli / Collaborator ED - Paolo, Bergese / Collaborator ED - Irene, Bertolini / Collaborator ED - Asima, Bhattacharyya / Collaborator ED - Suvendra, N Bhattacharyya / Collaborator ED - Steven, J Biller / Collaborator ED - Clotilde, Billottet / Collaborator ED - John, J Bissler / Collaborator ED - Olivier, Blanc-Brude / Collaborator ED - Cherie, Blenkiron / Collaborator ED - Charles, J Blijdorp / Collaborator ED - Sylwia, Bobis-Wozowicz / Collaborator ED - Victor, Bodart-Santos / Collaborator ED - Bodnár, Bernadett Réka / Collaborator ED - Eric, Boilard / Collaborator ED - Wilfrid, Boireau / Collaborator ED - Vladimir, Bokun / Collaborator ED - Stephanie, M Bollard / Collaborator ED - Sveva, Bollini / Collaborator ED - Antonella, Bongiovanni / Collaborator ED - Laura, Bongiovanni / Collaborator ED - Amandine, Bonifay / Collaborator ED - Marni, D Boppart / Collaborator ED - Francesc, E Borràs / Collaborator ED - Steffi, Bosch / Collaborator ED - Daniela, Boselli / Collaborator ED - Massimo, Bottini / Collaborator ED - Jeff, Bouffard / Collaborator ED - Chantal, M Boulanger / Collaborator ED - Paul, C Boutros / Collaborator ED - Oscar, Boyadjian / Collaborator ED - Anders, T Boysen / Collaborator ED - Batuhan, T Bozkurt / Collaborator ED - Kyle, P Bramich / Collaborator ED - Fabian, Braun / Collaborator ED - Rocío, del Carmen Bravo-Miana / Collaborator ED - Xandra, O Breakefield / Collaborator ED - Santra, Brenna / Collaborator ED - Kieran, Brennan / Collaborator ED - Meadhbh, Á Brennan / Collaborator ED - Koen, Breyne / Collaborator ED - Esther, M Bridges / Collaborator ED - David, R Brigstock / Collaborator ED - Alain, R Brisson / Collaborator ED - Chaya, Brodie / Collaborator ED - Marco, Brucale / Collaborator ED - Katelyn, A Bruno / Collaborator ED - Cecilia, Bucci / Collaborator ED - Shilpa, Buch / Collaborator ED - Amy, H Buck / Collaborator ED - Bukva, Mátyás / Collaborator ED - Jeff, WM Bulte / Collaborator ED - Sandra, Buratta / Collaborator ED - Dylan, Burger / Collaborator ED - Olivier, Burgy / Collaborator ED - Julia, V Burnier / Collaborator ED - Kaiping, Burrows / Collaborator ED - Sara, Busatto / Collaborator ED - Benedetta, Bussolati / Collaborator ED - Buzás, Edit Irén / Collaborator ED - Buzás, Krisztina / Collaborator ED - J, Brian Byrd / Collaborator ED - Albano, Cáceres-Verschae / Collaborator ED - Houjian, Cai / Collaborator ED - Hugo, R Caires / Collaborator ED - Carmen, Campos-Silva / Collaborator ED - Giovanni, Camussi / Collaborator ED - Paola, de Candia / Collaborator ED - Carmen, Carceller / Collaborator ED - Carmen, Fernandez-Becerra / Collaborator ED - Randy, P Carney / Collaborator ED - Alexis, G Murillo Carrasco / Collaborator ED - David, RF Carter / Collaborator ED - Serena, Cavallaro / Collaborator ED - Paola, de Candia / Collaborator ED - Carmen, Fernandez-Becerra / Collaborator ED - Randy, P Carney / Collaborator ED - Alexis, G Murillo Carrasco / Collaborator ED - David, RF Carter / Collaborator ED - Serena, Cavallaro / Collaborator ED - Sophie, Cavallero / Collaborator ED - Cristóbal, Cerda-Troncoso / Collaborator ED - Richard, Chahwan / Collaborator ED - Renata, Chalupská / Collaborator ED - Lawrence, W Chamley / Collaborator ED - Partha, K Chandra / Collaborator ED - Wen-Wei, Chang / Collaborator ED - Al, Charest / Collaborator ED - Chihchen, Chen / Collaborator ED - Hao, Chen / Collaborator ED - Qiang, Chen / Collaborator ED - Shuai, Chen / Collaborator ED - Siyu, Chen / Collaborator ED - Yunxi, Chen / Collaborator ED - Lesley, Cheng / Collaborator ED - Vasiliy, S Chernyshev / Collaborator ED - Venkatesh, Kumar Chetty / Collaborator ED - Sai, V Chitti / Collaborator ED - Ssang-Goo, Cho / Collaborator ED - Yoon-Kyoung, Cho / Collaborator ED - Byeong, Hyeon Choi / Collaborator ED - Somchai, Chutipongtanate / Collaborator ED - Maria, Elena Cicardi / Collaborator ED - Anna, Cifuentes-Rius / Collaborator ED - Alessandra, Ciullo / Collaborator ED - Aled, Clayton / Collaborator ED - Jacob, A Cleary / Collaborator ED - Federico, Cocozza / Collaborator ED - Emanuele, Cocucci / Collaborator ED - Robert, J Coffey / Collaborator ED - Federica, Collino / Collaborator ED - Federico, Colombo / Collaborator ED - Pascal, Colosetti / Collaborator ED - Alvaro, Compañ-Bertomeu / Collaborator ED - Julie, Constanzo / Collaborator ED - Denis, Corbeil / Collaborator ED - Anabela, Cordeiro-da-Silva / Collaborator ED - Júlia, Costa / Collaborator ED - Yvonne, Couch / Collaborator ED - Yvan, Courageux / Collaborator ED - Kelly, Coutant / Collaborator ED - Beth, Coyle / Collaborator ED - Rossella, Crescitelli / Collaborator ED - Marina, Cretich / Collaborator ED - André, Cronemberger-Andrade / Collaborator ED - Rachel, E Crossland / Collaborator ED - Marcela, A Cucher / Collaborator ED - Malgorzata, Czystowska-Kuzmicz / Collaborator ED - Pasquale, D'Acunzo / Collaborator ED - Igea, D'Agnano / Collaborator ED - Vito, G D'Agostino / Collaborator ED - Daniele, D'Arrigo / Collaborator ED - Crislyn, D'Souza-Schorey / Collaborator ED - Raghubendra, S Dagur / Collaborator ED - Kirsty, M Danielson / Collaborator ED - Saumya, Das / Collaborator ED - Thibaud, Dauphin / Collaborator ED - Sean, M Davidson / Collaborator ED - Owen, G Davies / Collaborator ED - Rebecca, L Davies / Collaborator ED - Chelsea, N Davis / Collaborator ED - Gagan, Deep / Collaborator ED - Jonathan, Degosserie / Collaborator ED - Mats, Van Delen / Collaborator ED - Vatsal, Deliwala / Collaborator ED - Elizabeth, R Dellar / Collaborator ED - Jan, Van Deun / Collaborator ED - Apurba, Dev / Collaborator ED - Sarah, Deville / Collaborator ED - Andrew, Devitt / Collaborator ED - Bert, Dhondt / Collaborator ED - Lothar, C Dieterich / Collaborator ED - Dirk, P Dittmer / Collaborator ED - Brian, Dobosh / Collaborator ED - Dobra, Gabriella / Collaborator ED - Navneet, Dogra / Collaborator ED - Eisuke, Dohi / Collaborator ED - Vincenza, Dolo / Collaborator ED - Timothy, V Domashevich / Collaborator ED - Massimo, Dominici / Collaborator ED - Liang, Dong / Collaborator ED - Etienne, Doré / Collaborator ED - Rebecca, A Dragovic / Collaborator ED - Tom, AP Driedonks / Collaborator ED - Lila, Drittanti / Collaborator ED - Marvin, Droste / Collaborator ED - Wei, Duan / Collaborator ED - Esmahan, Durmaz / Collaborator ED - Suman, Dutta / Collaborator ED - Takanori, Eguchi / Collaborator ED - Ramon, M Eichenberger / Collaborator ED - Erez, Eitan / Collaborator ED - Karin, Ekström / Collaborator ED - Maria, Eldh / Collaborator ED - Celine, Elie-Caille / Collaborator ED - Agustin, Enciso-Martinez / Collaborator ED - Uta, Erdbrügger / Collaborator ED - Rezvan, Esmaeili / Collaborator ED - Camille, Ettelaie / Collaborator ED - Försönits, András / Collaborator ED - Muller, Fabbri / Collaborator ED - Marco, Falasca / Collaborator ED - Juan, M Falcon-Perez / Collaborator ED - Hongkuan, Fan / Collaborator ED - Farah, Fatima / Collaborator ED - Vroniqa, Ku'ulei-Lyn Faustino / Collaborator ED - Alireza, Fazeli / Collaborator ED - María, Fernández-Rhodes / Collaborator ED - Christopher, Fernandez-Prada / Collaborator ED - Mariola, J Ferraro / Collaborator ED - Joao, N Ferreira / Collaborator ED - Rafaela, F Ferreira / Collaborator ED - Leandra, K Figueroa-Hall / Collaborator ED - Aliosha, I Figueroa-Valdés / Collaborator ED - Paolo, V Fioretti / Collaborator ED - Sabine, Flenady / Collaborator ED - Miguel, Flores-Bellver / Collaborator ED - Ellis, K Fok / Collaborator ED - Pamali, Fonseka / Collaborator ED - Karen, Forbes / Collaborator ED - Verity, J Ford / Collaborator ED - Cristina, Fornaguera / Collaborator ED - Dorian, Forte / Collaborator ED - Stefano, Forte / Collaborator ED - Orazio, Fortunato / Collaborator ED - Jeffrey, L Franklin / Collaborator ED - Daniela, Freitas / Collaborator ED - Annie, Frelet-Barrand / Collaborator ED - Qing-Ling, Fu / Collaborator ED - Yu, Fujita / Collaborator ED - Kathrin, Gärtner / Collaborator ED - André, Görgens / Collaborator ED - Áurea, M Gabriel / Collaborator ED - Martina, Gabrielli / Collaborator ED - Susanne, Gabrielsson / Collaborator ED - Galinsoga, Alicia / Collaborator ED - Andrea, Galisova / Collaborator ED - Teena, KJB Gamage / Collaborator ED - Yingtang, Gao / Collaborator ED - Marta, Garcia-Contreras / Collaborator ED - M, Madhy Garcia Garcia / Collaborator ED - Maria, Noé Garcia / Collaborator ED - Ernesto, Gargiulo / Collaborator ED - Hernán, González-King Garibotti / Collaborator ED - Margaret, M Mc Gee / Collaborator ED - Géraldine, C Genard / Collaborator ED - Fabiana, Geraci / Collaborator ED - Jamal, Ghanam / Collaborator ED - Subhadip, Ghatak / Collaborator ED - Mahlegha, Ghavami / Collaborator ED - Raluca, E Ghebosu / Collaborator ED - Yong, Song Gho / Collaborator ED - Ghosal, Sayam / Collaborator ED - Georgios, Giamas / Collaborator ED - Bernd, Giebel / Collaborator ED - Caroline, Gilbert / Collaborator ED - Mario, Gimona / Collaborator ED - Henrique, Girão / Collaborator ED - Ilaria, Giusti / Collaborator ED - Evan, A Gizzie / Collaborator ED - Sofija, Glamočlija / Collaborator ED - Sarah, E Glass / Collaborator ED - Jessica, Gobbo / Collaborator ED - Deborah, CI Goberdhan / Collaborator ED - Nihar, Godbole / Collaborator ED - Jacky, G Goetz / Collaborator ED - Olesia, Gololobova / Collaborator ED - Manuel, Gomez-Florit / Collaborator ED - Jenifer, Pendiuk Goncalves / Collaborator ED - Cansu, Gorgun / Collaborator ED - Alessandro, Gori / Collaborator ED - Sabina, Gorska / Collaborator ED - Michael, W Graner / Collaborator ED - Georges, E Grau / Collaborator ED - Laura, Grech / Collaborator ED - David, W Greening / Collaborator ED - Rüdiger, M Groß / Collaborator ED - Julia, C Gross / Collaborator ED - Jens, Gruber / Collaborator ED - Alice, Gualerzi / Collaborator ED - Dominic, Guanzon / Collaborator ED - Johann, M Gudbergsson / Collaborator ED - Coralie, L Guerin / Collaborator ED - Flora, Guerra / Collaborator ED - Maria, I Guillén / Collaborator ED - Vikramsingh, Gujar / Collaborator ED - Wei, Guo / Collaborator ED - Veer, Bala Gupta / Collaborator ED - Vivek, Kumar Gupta / Collaborator ED - Dakota, Gustafson / Collaborator ED - Gyukity-Sebestyén, Edina / Collaborator ED - Patrick, Hölker / Collaborator ED - Mangesh, D Hade / Collaborator ED - Daniel, W Hagey / Collaborator ED - Colin, L Hisey / Collaborator ED - Fred, H Hochberg / Collaborator ED - Esther, NM Nolte-'t Hoen / Collaborator ED - Marija, Holcar / Collaborator ED - Beth, Holder / Collaborator ED - Wolfgang, Holnthoner / Collaborator ED - Harry, Holthofer / Collaborator ED - D, Craig Hooper / Collaborator ED - Nicole, Noren Hooten / Collaborator ED - Elham, Hosseini-Beheshti / Collaborator ED - Baharak, Hosseinkhani / Collaborator ED - Kathryn, L Howe / Collaborator ED - Nicholas, R Hoyle / Collaborator ED - Jiri, Hrdy / Collaborator ED - Guoku, Hu / Collaborator ED - Yiyao, Huang / Collaborator ED - Veronica, Huber / Collaborator ED - Samo, Hudoklin / Collaborator ED - Antonia, Hufnagel / Collaborator ED - Mark, D Hulett / Collaborator ED - Stuart, Hunt / Collaborator ED - Vincent, Hyenne / Collaborator ED - Emilio, Di Ianni / Collaborator ED - Dalila, Iannotta / Collaborator ED - Ahmed, GE Ibrahim / Collaborator ED - Sherif, A Ibrahim / Collaborator ED - Seiko, Ikezu / Collaborator ED - Tsuneya, Ikezu / Collaborator ED - Hyungsoon, Im / Collaborator ED - Jameel, M Inal / Collaborator ED - Aleksandra, Inic-Kanada / Collaborator ED - Marit, Inngjerdingen / Collaborator ED - Yasuo, Inoshima / Collaborator ED - Alexander, R Ivanov / Collaborator ED - Alena, Ivanova / Collaborator ED - Elena, Izquierdo / Collaborator ED - Malene, Møller Jørgensen / Collaborator ED - Hannah, K Jackson / Collaborator ED - Soren, Jacobsen / Collaborator ED - Fernanda, Jadue / Collaborator ED - Naureen, Javeed / Collaborator ED - Steven, M Jay / Collaborator ED - Muthuvel, Jayachandran / Collaborator ED - Migara, K Jayasinghe / Collaborator ED - Guido, Jenster / Collaborator ED - Dennis, K Jeppesen / Collaborator ED - Carmen, Jerónimo / Collaborator ED - Linglei, Jiang / Collaborator ED - Jing, Jin / Collaborator ED - Kentaro, Jingushi / Collaborator ED - Dong-Gyu, Jo / Collaborator ED - Marianne, S Joerger-Messerli / Collaborator ED - Jennifer, C Jones / Collaborator ED - Melissa, K Jones / Collaborator ED - Olivier, G de Jong / Collaborator ED - Tijana, Jovanovic-Talisman / Collaborator ED - Anthony, W Ferrante / Collaborator ED - Leon, G Coleman Jr / Collaborator ED - David, Juncker / Collaborator ED - Stephanie, Jung / Collaborator ED - Benjamin, Jurek / Collaborator ED - Marcin, Jurga / Collaborator ED - Verline, Justilien / Collaborator ED - Mehdi, Kabani / Collaborator ED - Raghu, Kalluri / Collaborator ED - Masood, Kamali-Moghaddam / Collaborator ED - Masamitsu, Kanada / Collaborator ED - Taeyoung, Kang / Collaborator ED - Shin-ichi, Kano / Collaborator ED - Maria, Kaparakis-Liaskos / Collaborator ED - Elżbieta, Karnas / Collaborator ED - Antoine, Karoichan / Collaborator ED - Fatah, Kashanchi / Collaborator ED - Sara, Assar Kashani / Collaborator ED - Namita, N Kashyap / Collaborator ED - Miroslava, Katsur / Collaborator ED - Silvio, Kau-Strebinger / Collaborator ED - Amy, C Kauffman / Collaborator ED - Sukhbir, Kaur / Collaborator ED - Oksana, Kehoe / Collaborator ED - Richard, JR Kelwick / Collaborator ED - Amirmohammad, Nasiri Kenari / Collaborator ED - Kestecher, Brachyahu Meir / Collaborator ED - Tom, G Keulers / Collaborator ED - Kendall, R Van Keuren-Jensen / Collaborator ED - Kasra, Khalaj / Collaborator ED - Khamari, Delaram / Collaborator ED - Ramin, Khanabdali / Collaborator ED - Elena, Khomyakova / Collaborator ED - Amanda, Khoo / Collaborator ED - Daniel, H Kim / Collaborator ED - Dongin, Kim / Collaborator ED - Han, Sang Kim / Collaborator ED - In-San, Kim / Collaborator ED - Soo, Kim / Collaborator ED - Yohan, Kim / Collaborator ED - Peter, E Kima / Collaborator ED - Thomas, Kislinger / Collaborator ED - Mikael, Klingeborn / Collaborator ED - Rob, Knight / Collaborator ED - Hiroaki, Komuro / Collaborator ED - Koncz, Anna / Collaborator ED - Timothea, Konstantinou / Collaborator ED - Luke, van der Koog / Collaborator ED - Sander, AA Kooijmans / Collaborator ED - Miroslaw, T Kornek / Collaborator ED - Maja, Kosanović / Collaborator ED - Enis, Kostallari / Collaborator ED - Tiana, F Koukoulis / Collaborator ED - Stella, Kourembanas / Collaborator ED - Eva-Maria, Krämer-Albers / Collaborator ED - Veronika, Kralj-Iglic / Collaborator ED - Susanne, Krasemann / Collaborator ED - Anna, D Krasnodembskaya / Collaborator ED - Natalia, J Krawczynska / Collaborator ED - Nicole, A Kruh-Garcia / Collaborator ED - Meta, J Kuehn / Collaborator ED - Marije, E Kuipers / Collaborator ED - Konxhe, Kulaj / Collaborator ED - Julia, Kuligowski / Collaborator ED - Yumi, Kumagai / Collaborator ED - Ashish, Kumar / Collaborator ED - Saroj, Kumar / Collaborator ED - Sharad, Kumar / Collaborator ED - Meena, Kumari / Collaborator ED - Gabrielis, Kundrotas / Collaborator ED - Igor, V Kurochkin / Collaborator ED - Masahiko, Kuroda / Collaborator ED - Marzena, Kurzawa-Akanbi / Collaborator ED - Sasha, J Kweskin / Collaborator ED - Diego, Kyburz / Collaborator ED - Elisa, Lázaro-Ibáñez / Collaborator ED - Cecilia, Lässer / Collaborator ED - Jan, Lötvall / Collaborator ED - Lőrincz, Márton Ákos / Collaborator ED - Andrew, Lai / Collaborator ED - Charles, P Lai / Collaborator ED - Saara, Laitinen / Collaborator ED - Solange, Landreville / Collaborator ED - Sigrun, Lange / Collaborator ED - Scott, M Langevin / Collaborator ED - Marc-André, Langlois / Collaborator ED - Lucia, R Languino / Collaborator ED - Joanne, Lannigan / Collaborator ED - Daniel, S Lark / Collaborator ED - Adriana, T Larregina / Collaborator ED - Louise, C Laurent / Collaborator ED - David, Laurin / Collaborator ED - Gregory, Lavieu / Collaborator ED - Charlotte, Lawson / Collaborator ED - Soazig, Le Lay / Collaborator ED - Kevin, Leandro / Collaborator ED - Aurélie, Ledreux / Collaborator ED - Changjin, Lee / Collaborator ED - Dong-Sup, Lee / Collaborator ED - Hakho, Lee / Collaborator ED - Heon-Jin, Lee / Collaborator ED - Sun, Young Lee / Collaborator ED - Tae, Ryong Lee / Collaborator ED - Wai-Leng, Lee / Collaborator ED - Iliya, Lefterov / Collaborator ED - Xinhua, Lei / Collaborator ED - Janne, Leivo / Collaborator ED - Quentin, Lemaire / Collaborator ED - Adriana, F Paes Leme / Collaborator ED - Stanley, M Lemon / Collaborator ED - Metka, Lenassi / Collaborator ED - Kathleen, M. Lennon / Collaborator ED - Stephen, Lenzini / Collaborator ED - Jonathan, Leor / Collaborator ED - Efrat, levy / Collaborator ED - Bo, Li / Collaborator ED - Guoping, Li / Collaborator ED - Jiao, Jiao Li / Collaborator ED - Qiubai, Li / Collaborator ED - Xinlei, Li / Collaborator ED - Xiuming, Liang / Collaborator ED - Rebecca, Lim / Collaborator ED - Sai, Kiang Lim / Collaborator ED - Tania, Limongi / Collaborator ED - Aija, Linē / Collaborator ED - Paula, Pincela Lins / Collaborator ED - Lien, Lippens / Collaborator ED - Guanshu, Liu / Collaborator ED - Alicia, Llorente / Collaborator ED - Modeline, N Longjohn / Collaborator ED - Fons, AJ van de Loo / Collaborator ED - Magdalena, J Lorenowicz / Collaborator ED - Aurelio, Lorico / Collaborator ED - Olivier, Loudig / Collaborator ED - Xavier, Loyer / Collaborator ED - Estefanía, Lozano-Andrés / Collaborator ED - Biao, Lu / Collaborator ED - Quan, Lu / Collaborator ED - Quentin, Lubart / Collaborator ED - Fabrice, Lucien / Collaborator ED - Taral, R Lunavat / Collaborator ED - Ludwig, Ermann Lundberg / Collaborator ED - David, J Lundy / Collaborator ED - Jens, C Luoto / Collaborator ED - David, C Lyden / Collaborator ED - Andreas, Möller / Collaborator ED - Janis, A Müller / Collaborator ED - Daniel, J MacPhee / Collaborator ED - Adam, L. Maddox / Collaborator ED - Elise, Madec / Collaborator ED - Setty, M Magaña / Collaborator ED - Vasiliki, Mahairaki / Collaborator ED - Mỹ, G Mahoney / Collaborator ED - Harmeet, Malhi / Collaborator ED - Cécile, E Malnou / Collaborator ED - Doste, R Mamand / Collaborator ED - Kenny, Man / Collaborator ED - Mauro, Manno / Collaborator ED - Pierre-Yves, Mantel / Collaborator ED - Tecla, Marangon / Collaborator ED - Eduardo, Marbán / Collaborator ED - Antonio, Marcilla / Collaborator ED - Krishna, P Maremanda / Collaborator ED - Leonid, Margolis / Collaborator ED - Luis, Mariñas-Pardo / Collaborator ED - Ivica, Marić / Collaborator ED - Silvia, Sánchez Martín / Collaborator ED - Eduardo, Martínez-Martínez / Collaborator ED - Catherine, Martel / Collaborator ED - Elena, S Martens-Uzunova / Collaborator ED - Pilar, Martin-Duque / Collaborator ED - Lorena, Martin-Jaular / Collaborator ED - Paola, A Martinez-Murillo / Collaborator ED - Sarai, Martinez-Pacheco / Collaborator ED - Tania, Martins-Marques / Collaborator ED - Benjamin, Mary / Collaborator ED - Akbar, L Marzan / Collaborator ED - Andreu, Matamoros-Angles / Collaborator ED - Suresh, Mathivanan / Collaborator ED - Juntaro, Matsuzaki / Collaborator ED - Maria, D Mayan / Collaborator ED - Carla, Mazzeo / Collaborator ED - Mariama, Mbengue / Collaborator ED - Mark, J McCann / Collaborator ED - Luke, C McIlvenna / Collaborator ED - Mark, J McVey / Collaborator ED - Nicole, Meisner-Kober / Collaborator ED - Maiken, Mellergaard / Collaborator ED - Giorgia, Melli / Collaborator ED - Kerstin, Menck / Collaborator ED - Nico, G Menjivar / Collaborator ED - Ramkumar, Menon / Collaborator ED - Kyle, I Mentkowski / Collaborator ED - John, J Miklavcic / Collaborator ED - Andras, G Miklosi / Collaborator ED - Bojana, Milutinovic / Collaborator ED - Valentina, R Minciacchi / Collaborator ED - Mehdi, Mirzaei / Collaborator ED - Shalini, Mishra / Collaborator ED - Megan, I Mitchell / Collaborator ED - Rachel, R Mizenko / Collaborator ED - Danilo, Mladenović / Collaborator ED - Eqbal, Mohamadi / Collaborator ED - Sujata, Mohanty / Collaborator ED - Fatemeh, Momen-Heravi / Collaborator ED - Sujan, K Mondal / Collaborator ED - Marta, Monguió-Tortajada / Collaborator ED - Jisook, Moon / Collaborator ED - Mattia, I Morandi / Collaborator ED - Violaine, Moreau / Collaborator ED - Lissette, Retana Moreira / Collaborator ED - Adrian, E Morelli. / Collaborator ED - Marcelo, A Mori / Collaborator ED - Masahiro, Morimoto / Collaborator ED - Mathilde, Mosser / Collaborator ED - Thabiso, E Motaung / Collaborator ED - Etienne, Moussay / Collaborator ED - Vera, Mugoni / Collaborator ED - Francois, Mullier / Collaborator ED - Maurizio, Muraca / Collaborator ED - Saravanakumar, Murugesan / Collaborator ED - Luca, Musante / Collaborator ED - Angelo, Musicò / Collaborator ED - Németh, Afrodité / Collaborator ED - Németh, Krisztina / Collaborator ED - Amélie, Nadeau / Collaborator ED - Gi-Hoon, Nam / Collaborator ED - Honami, Naora / Collaborator ED - Riccardo, Natoli / Collaborator ED - Muhammad, Nawaz / Collaborator ED - Irina, Nazarenko / Collaborator ED - Justus, C Ndukaife / Collaborator ED - Christina, Nedeva / Collaborator ED - Peter, Nejsum / Collaborator ED - Inge, Nelissen / Collaborator ED - Christian, Neri / Collaborator ED - Tommaso, Neri / Collaborator ED - Paolo, Neviani / Collaborator ED - Lauren, A Newman / Collaborator ED - Chiew, Yong Ng / Collaborator ED - Guillaume, van Niel / Collaborator ED - Rienk, Nieuwland / Collaborator ED - Nadezhda, Nikiforova / Collaborator ED - Leonardo, Nimrichter / Collaborator ED - Chitranshi, Nitin / Collaborator ED - Makon-Sébastien, Njock / Collaborator ED - Daniele, Noël / Collaborator ED - Alessio, Noghero / Collaborator ED - John, P Nolan / Collaborator ED - Sam, Noppen / Collaborator ED - Antonio, da Silva Novaes / Collaborator ED - Lorraine, O'Driscoll / Collaborator ED - Ana, O'Loghlen / Collaborator ED - Takahiro, Ochiya / Collaborator ED - Johannes, Oesterreicher / Collaborator ED - Seung, W Oh / Collaborator ED - Oláh, Attila / Collaborator ED - Martin, Olivier / Collaborator ED - Siew, Ling Ong / Collaborator ED - Angelica, Ortiz / Collaborator ED - Luis, A Ortiz / Collaborator ED - Ole, Østergaard / Collaborator ED - Omar, A Osorio / Collaborator ED - Osteikoetxea, Xabier / Collaborator ED - Matias, Ostrowski / Collaborator ED - David, Otaegui / Collaborator ED - Alexander, Otahal / Collaborator ED - Patricia, M M Ozawa / Collaborator ED - Dilara, C Ozkocak / Collaborator ED - Pálóczi, Krisztina / Collaborator ED - Rocío, Pérez-González / Collaborator ED - Bianca, C Pachane / Collaborator ED - Hafiza, Padinharayil / Collaborator ED - Daan, Paget / Collaborator ED - Jerome, Paggetti / Collaborator ED - Paola, C Loreto Palacio / Collaborator ED - Christian, P Pallasch / Collaborator ED - Roberta, Palmulli / Collaborator ED - Bairen, Pang / Collaborator ED - Liliia, Paniushkina / Collaborator ED - Paschalia, Pantazi / Collaborator ED - Lucia, Paolini / Collaborator ED - Daniela, L Papademetrio / Collaborator ED - Pietro, Parisse / Collaborator ED - Dong, Jun Park / Collaborator ED - Juhee, Park / Collaborator ED - Young-Gyun, Park / Collaborator ED - James, G Patton / Collaborator ED - Nicholas, J Peake / Collaborator ED - D, Michiel Pegtel / Collaborator ED - Héctor, Peinado / Collaborator ED - Francesca, Perut / Collaborator ED - Michael, W Pfaffl / Collaborator ED - Annika, Pfeiffer / Collaborator ED - Thanh, Kha Phan / Collaborator ED - Donald, G Phinney / Collaborator ED - Leonidas, A Phylactou / Collaborator ED - Silvia, Picciolini / Collaborator ED - Monika, Pietrowska / Collaborator ED - Max, Piffoux / Collaborator ED - Cláudio, Pinheiro / Collaborator ED - Ryan, C Pink / Collaborator ED - Michelle, L Pleet / Collaborator ED - Gabriella, Pocsfalvi / Collaborator ED - Qi, Hui Poh / Collaborator ED - Edwin, van der Pol / Collaborator ED - Ganesha, Poojary / Collaborator ED - Ivan, KH Poon / Collaborator ED - Giuseppina, Poppa / Collaborator ED - Hernando, A del Portillo / Collaborator ED - Vendula, Pospichalova / Collaborator ED - Shirley, Potter / Collaborator ED - Bonita, H Powell / Collaborator ED - Simon, J Powis / Collaborator ED - Ilaria, Prada / Collaborator ED - Indira, Prasadam / Collaborator ED - Christian, Preußer / Collaborator ED - Heather, H Pua / Collaborator ED - Ferdinando, Pucci / Collaborator ED - Florian, Puhm / Collaborator ED - Berta, Puig / Collaborator ED - Lynn, Pulliam / Collaborator ED - Adityas, Purnianto / Collaborator ED - Johanna, MM Puutio / Collaborator ED - Rachel, C Quilang / Collaborator ED - Piul, S Rabbani / Collaborator ED - Gorjana, Rackov / Collaborator ED - Annalisa, Radeghieri / Collaborator ED - Claudia, M Radu / Collaborator ED - Robert, L Raffai / Collaborator ED - Alok, Raghav / Collaborator ED - Mohammad, Rahbari / Collaborator ED - MD, Matiur Rahman / Collaborator ED - Md, Mostafizur Rahman / Collaborator ED - Alex, J Rai / Collaborator ED - Stefania, Raimondo / Collaborator ED - Sneha, Raju / Collaborator ED - Janusz, Rak / Collaborator ED - Lausonia, Ramaswamy / Collaborator ED - Javier, Ramirez-Ricardo / Collaborator ED - Marcel, I Ramirez / Collaborator ED - Shikha, Rani / Collaborator ED - Graca, Raposo / Collaborator ED - Hilal, A Rather / Collaborator ED - Agnieszka, Razim / Collaborator ED - Antonia, Reale / Collaborator ED - Eduardo, Reategui / Collaborator ED - Caroline, J Reddel / Collaborator ED - Shivakumar, K Reddy / Collaborator ED - Stephen, Redenti / Collaborator ED - Samantha, L Reed / Collaborator ED - Neta, Regev-Rudzki / Collaborator ED - Katrin, S Reiners / Collaborator ED - Nataša, Resnik / Collaborator ED - Gregory, E Rice / Collaborator ED - Franz, L Ricklefs / Collaborator ED - Andrea, Ridolfi / Collaborator ED - Kirsi, Rilla / Collaborator ED - Michael, P Rimmer / Collaborator ED - Kelly, CS Roballo / Collaborator ED - Paul, D Robbins / Collaborator ED - David, D Roberts / Collaborator ED - Jordi, Roca / Collaborator ED - Avital, A Rodal / Collaborator ED - Dorival, M Rodrigues-Junior / Collaborator ED - Marcio, L Rodrigues / Collaborator ED - Marieke, T Roefs / Collaborator ED - Russell, G Rogers / Collaborator ED - Eva, Rohde / Collaborator ED - Tatu, Rojalin / Collaborator ED - Rita, Romani / Collaborator ED - Miriam, Romano / Collaborator ED - Sophie, Rome / Collaborator ED - Rok, Romih / Collaborator ED - Anna, Romolo / Collaborator ED - Tatiane, De Rossi / Collaborator ED - Kasper, M Rouschop / Collaborator ED - David, A Routenberg / Collaborator ED - Quentin, Roux / Collaborator ED - Andrew, Rowland / Collaborator ED - Martin, E van Royen / Collaborator ED - Annaïg, J Rozo / Collaborator ED - David, Rufino-Ramos / Collaborator ED - Aurelia, Rughetti / Collaborator ED - Ashley, E Russell / Collaborator ED - Stephanie, F Rutter / Collaborator ED - Myltykbay, S Rysmakhanov / Collaborator ED - Catherine, A Sánchez / Collaborator ED - Yoel, Sadovsky / Collaborator ED - Reihaneh, Safavi-Sohi / Collaborator ED - Andras, Saftics / Collaborator ED - Ram, Sagar / Collaborator ED - Susmita, Sahoo / Collaborator ED - Nathaniel, EB Saidu / Collaborator ED - Julien, Saint-Pol / Collaborator ED - Edison, Salas-Huenuleo / Collaborator ED - Ana, I Salazar-Puerta / Collaborator ED - Ayesha, Saleem / Collaborator ED - Ghasem, Hosseini Salekdeh / Collaborator ED - Carlos, Salomon / Collaborator ED - Amanda, Salviano-Silva / Collaborator ED - Amankeldi, A Salybekov / Collaborator ED - Mark, Samuels / Collaborator ED - Ursula, S Sandau / Collaborator ED - Jascinta, P Santavanond / Collaborator ED - Jessie, Santoro / Collaborator ED - Mark, Santos / Collaborator ED - Rahul, Sanwlani / Collaborator ED - Julie, A Saugstad / Collaborator ED - Meike, J Saul / Collaborator ED - Tine, Hiorth Schøyen / Collaborator ED - Irma, Schabussova / Collaborator ED - Emilia, Scharrig / Collaborator ED - Randy, Schekman / Collaborator ED - Jessica, Schiavi-Tritz / Collaborator ED - Raymond, M Schiffelers / Collaborator ED - Anna, M Schmid / Collaborator ED - Raphael, Schneider / Collaborator ED - Stefan, Schneider / Collaborator ED - Andreina, Schoeberlein / Collaborator ED - Jeffrey, S Schorey / Collaborator ED - Naohiro, Seo / Collaborator ED - Joaquin, Seras-Franzoso / Collaborator ED - Sanjay, Shahi / Collaborator ED - Olga, Shatnyeva / Collaborator ED - Deanna, F Shea / Collaborator ED - Faezeh, Shekari / Collaborator ED - Ganesh, V Shelke / Collaborator ED - Ashok, K Shetty / Collaborator ED - Kiyotaka, Shiba / Collaborator ED - Thomas, Michael Shiju / Collaborator ED - Surya, Shrivastava / Collaborator ED - Sachin, Shukla / Collaborator ED - Pia, R-M Siljander / Collaborator ED - Andreia, M Silva / Collaborator ED - Ajay, P Singh / Collaborator ED - Sangeeta, Singh / Collaborator ED - Mikhail, Skliar / Collaborator ED - Johan, Skog / Collaborator ED - Joost, PG Sluijter / Collaborator ED - Orman, L Snyder / Collaborator ED - Carolina, Soekmadji / Collaborator ED - Ahmed, Somaida / Collaborator ED - Masaharu, Somiya / Collaborator ED - Karolina, Soroczyńska / Collaborator ED - Javier, Sotillo / Collaborator ED - Fernando, Souza-Fonseca-Guimaraes / Collaborator ED - Sheila, Spada / Collaborator ED - Harry, VM Spiers / Collaborator ED - Joshua, D Spitzberg / Collaborator ED - Akhil, Srivastava / Collaborator ED - Amit, K Srivastava / Collaborator ED - Ewa, Ł Stępień / Collaborator ED - Frederic, St-Denis-Bissonnette / Collaborator ED - Philip, D Stahl / Collaborator ED - Janine, Stam / Collaborator ED - Oumaima, Stambouli / Collaborator ED - Bruce, A Stanton / Collaborator ED - Frank, RM Stassen / Collaborator ED - Oskar, Staufer / Collaborator ED - Loïc, Steiner / Collaborator ED - Stepanova, Ganna / Collaborator ED - Veronika, Stoka / Collaborator ED - Willem, Stoorvogel / Collaborator ED - Elke, Pogge von Strandmann / Collaborator ED - Dirk, Strunk / Collaborator ED - Stanley, S Stylli / Collaborator ED - Huaqi, Su / Collaborator ED - Subbaya, Subramanian / Collaborator ED - Bingdong, Sui / Collaborator ED - Sonal, Sukreet / Collaborator ED - Elias, Sulaiman / Collaborator ED - Bong, Hwan Sung / Collaborator ED - Vijaya, Sunkara / Collaborator ED - Zucai, Suo / Collaborator ED - Per, Svenningsen / Collaborator ED - Julian, Swatler / Collaborator ED - Simon, Swift / Collaborator ED - Emma, KC Symonds / Collaborator ED - Szeifert, Viktória / Collaborator AU - Szigyártó, Imola Csilla ED - Tóth, Eszter Ágnes / Collaborator ED - Neslihan, P Taşlı / Collaborator ED - Hidetoshi, Tahara / Collaborator ED - Ryou-u, Takahashi / Collaborator ED - Yoshinobu, Takakura / Collaborator ED - Osamu, Takikawa / Collaborator ED - Kaloyan, Takov / Collaborator ED - Vera, A Tang / Collaborator ED - Simona, Taverna / Collaborator ED - Nadim, Tawil / Collaborator ED - Loes, Teeuwen / Collaborator ED - Sandra, Tejedor / Collaborator ED - Dmitry, Ter-Ovanesyan / Collaborator ED - Tobias, Tertel / Collaborator ED - Clotilde, Théry / Collaborator ED - Abhimanyu, Thakur / Collaborator ED - Tara, Thompson-Felix / Collaborator ED - Changhai, Tian / Collaborator ED - Aleksei, Tikhonov / Collaborator ED - Swasti, Tiwari / Collaborator ED - Wei, Seong Toh / Collaborator ED - John, J Tomes / Collaborator ED - Elisa, Tonoli / Collaborator ED - Ana, C Torrecilhas / Collaborator ED - Juan, P Tosar / Collaborator ED - Camille, V Trinidad / Collaborator ED - Lucienne, Tritten / Collaborator ED - Rucha, Trivedi / Collaborator ED - Zach, Troyer / Collaborator ED - Migmar, Tsamchoe / Collaborator ED - Vera, Tscherrig / Collaborator ED - Thupten, Tsering / Collaborator ED - Kristyna, Turkova / Collaborator ED - Oleg, S Tutanov / Collaborator ED - Koji, Ueda / Collaborator ED - Dinesh, Upadhya / Collaborator ED - Fumihiko, Urabe / Collaborator ED - Lorena, Urbanelli / Collaborator ED - Ornella, Urzì / Collaborator ED - Zivile, Useckaite / Collaborator ED - Elena, Vacchi / Collaborator ED - Pieter, Vader / Collaborator ED - Riccardo, Vago / Collaborator ED - Hadi, Valadi / Collaborator ED - Sami, Valkonen / Collaborator ED - Francesco, Valle / Collaborator ED - Manuel, Varas-Godoy / Collaborator ED - Zoltán, Varga / Collaborator ED - Zoltan, Varga / Collaborator ED - M, Helena Vasconcelos / Collaborator ED - Ivan, J Vechetti / Collaborator ED - Sara, I Veiga / Collaborator ED - Laura, J Vella / Collaborator ED - Émilie, Velot / Collaborator ED - Frederik, J Verweij / Collaborator ED - Beate, Vestad / Collaborator ED - Ludovic, Vinay / Collaborator ED - Margarida, Viola / Collaborator ED - Visnovitz, Tamás / Collaborator ED - Dolores, Di Vizio / Collaborator ED - Wyatt, N Vreeland / Collaborator ED - Visnovitzné Dr Vukman, Krisztina / Collaborator ED - Philippa, K Wade / Collaborator ED - Simonides, I van de Wakker / Collaborator ED - Lucas, Walther / Collaborator ED - Tong, Wang / Collaborator ED - Xiaoqin, Wang / Collaborator ED - Dionysios, C Watson / Collaborator ED - Marca, HM Wauben / Collaborator ED - Alissa, M Weaver / Collaborator ED - Jason, P Webber / Collaborator ED - Viktoria, Weber / Collaborator ED - Ann, M Wehman / Collaborator ED - Luisa, Weiss / Collaborator ED - Mark, L Weiss / Collaborator ED - René, Weiss / Collaborator ED - Ralph, Weissleder / Collaborator ED - Joshua, A Welsh / Collaborator ED - Yi, Wen / Collaborator ED - Olivier, de Wever / Collaborator ED - Asa, M Wheelock / Collaborator ED - Katherine, E White / Collaborator ED - Bradley, Whitehead / Collaborator ED - Theresa, L Whiteside / Collaborator ED - Joseph, Whitley / Collaborator ED - Wiener, Zoltán / Collaborator ED - Andre, J van Wijnen / Collaborator ED - Oscar, PB Wiklander / Collaborator ED - Sarah, Williams / Collaborator ED - Charisse, N Winston / Collaborator ED - Kenneth, W Witwer / Collaborator ED - Martin, Wolf / Collaborator ED - Joy, Wolfram / Collaborator ED - Liang, Wu / Collaborator ED - Yunjie, Wu / Collaborator ED - Magdalena, E Wysmołek / Collaborator ED - Patricia, Xander / Collaborator ED - Cristina, PR Xavier / Collaborator ED - Yu, Xiao / Collaborator ED - Rong, Xu / Collaborator ED - María, Yáñez-Mó / Collaborator ED - Tomofumi, Yamamoto / Collaborator ED - Yuki, Yamamoto / Collaborator ED - Yusuke, Yamamoto / Collaborator ED - Xiaomei, Yan / Collaborator ED - Lifang, Yang / Collaborator ED - Yongkang, Yang / Collaborator ED - Reza, Yarani / Collaborator ED - Kyungmoo, Yea / Collaborator ED - Laura, Yedigaryan / Collaborator ED - Vengala, Rao Yenuganti / Collaborator ED - Saigopalakrishna, S Yerneni / Collaborator ED - Vincent, Yeung / Collaborator ED - Yagmur, Yildizhan / Collaborator ED - Hang, Yin / Collaborator ED - Akira, Yokoi / Collaborator ED - Yusuke, Yoshioka / Collaborator ED - Yang, You / Collaborator ED - Ling-Qing, Yuan / Collaborator ED - Samuel, Tassi Yunga / Collaborator ED - Amin, Zakeri / Collaborator ED - Augusto, Zani / Collaborator ED - Michele, Zanoni / Collaborator ED - Valentina, Zappulli / Collaborator ED - Natasa, Zarovni / Collaborator ED - Jana, Zarubova / Collaborator ED - Janos, Zempleni / Collaborator ED - Vytautas, Žėkas / Collaborator ED - Andrea, Zendrini / Collaborator ED - Hao, Zhang / Collaborator ED - Qin, Zhang / Collaborator ED - Zheng, Zhao / Collaborator ED - Lei, Zheng / Collaborator ED - Yinghong, Zhou / Collaborator ED - Antje, M Zickler / Collaborator ED - Andries, Zijlstra / Collaborator ED - Alan, J Zimmerman / Collaborator ED - Pascale, Zimmermann / Collaborator ED - Angela, M Zivkovic / Collaborator ED - Davide, Zocco / Collaborator ED - Ewa, K Zuba-Surma / Collaborator AU - Haseeb, Zubair ED - Harmati, Mária / Collaborator ED - Hegyesi, Hargita / Collaborator TI - Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches JF - JOURNAL OF EXTRACELLULAR VESICLES J2 - J EXTRACELLULAR VESICL VL - 13 PY - 2024 IS - 2 PG - 84 SN - 2001-3078 DO - 10.1002/jev2.12404 UR - https://m2.mtmt.hu/api/publication/34567532 ID - 34567532 N1 - Translational Nanobiology Section, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, BethesdaMD, United States Nuffield Department of Women’s and Reproductive Health, University of Oxford, Women’s Centre, John Radcliffe Hospital, Oxford, United Kingdom School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland Trinity St. James’s Cancer Institute, Trinity College Dublin, Dublin, Ireland Department of Genetics, Celland Immunobiology, Semmelweis University, Budapest, Hungary HCEMM-SU Extracellular Vesicle Research Group, Semmelweis University, Budapest, Hungary HUN-REN-SU Translational Extracellular Vesicle Research Group, Semmelweis University, Budapest, Hungary Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy University of Georgia, Athens, GA, United States Department of Surgery, Division of Cancer Biology and Therapeutics, Cedars-Sinai Medical Center, Los Angeles, CA, United States Department CDL Research, University Medical Center Utrecht, Utrecht, Netherlands University of Virginia Health System, Charlottesville, VA, United States Exosomes Laboratory, Center for Cooperative Research in Biosciences, Basque Research and Technology Alliance, Derio, Spain Metabolomics Platform, Center for Cooperative Research in Biosciences, Basque Research and Technology Alliance, Derio, Spain IKERBASQUE, Basque Foundation for Science, Bilbao, Spain Otorhinolaryngology Hospital, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China Extracellular Vesicle Research and Clinical Translational Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China Institute for Health and Sport, Victoria University, Melbourne, Australia Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore Paracrine Therapeutics Pte. Ltd, Singapore, Singapore Department of Surgery, YLL School of Medicine, National University Singapore, Singapore, Singapore Thomas Jefferson University, Philadelphia, PA, United States Stem Cell Facility, All India Institute of Medical Sciences, New Delhi, India Chinese University of Hong Kong, Hong Kong QIMR Berghofer Medical Research Institute, Brisbane, Australia Laboratory of Experimental Clinical Chemistry, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, Netherlands Amsterdam Vesicle Center, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, Netherlands Tokyo Medical University, Tokyo, Japan Icahn School of Medicine at Mount Sinai, New York, NY, United States Laboratório de Imunologia Celular e Bioquímica de Fungos e Protozoários, Departamento de Ciências Farmacêuticas, Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo (UNIFESP) Campus Diadema, Diadema, Brazil Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, United States Genentech, South San Francisco, CA, United States Department of Molecular Medicine, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, CA, United States Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy Center for Colloid and Surface Science (CSGI), Florence, Italy National Center for Gene Therapy and Drugs based on RNA Technology, Padua, Italy Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom Consiglio Nazionale delle RicercheIstituto per lo Studio dei Materiali Nanostrutturati, Bologna, Italy Consorzio Interuniversitario per lo Sviluppo dei Sistemi a Grande Interfase, Florence, Italy Kidney Research Centre, Ottawa Hopsital Research Institute, Ottawa, Canada Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Canada School of Pharmaceutical Sciences, University of Ottawa, Ottawa, Canada Department of Biomedical Engineering, University of California, Davis, CA, United States Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH, United States Comprehensive Cancer Center, The Ohio State University, Columbus, OH, United States Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden Wallenberg Centre for Molecular and Translational Medicine, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden Department of Biomedicine, University Hospital Basel, Basel, Switzerland Department of Biomedicine, University of Basel, Basel, Switzerland Department of Oncology, University of Oxford, Oxford, United Kingdom Departments of Neurology and Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, United States Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, Ghent, Belgium Cancer Research Institute Ghent, Ghent, Belgium Barnett Institute of Chemical and Biological Analysis, Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States Department of Cancer Biology and Molecular Medicine, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, CA, United States Bio-pharmaceutical Manufacturing and Academic Resource Center (BioMARC), Infectious Disease Research Center, Colorado State University, Fort Collins, CO, United States Department of Rheumatology, University Hospital Basel, Basel, Switzerland Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden Krefting Research Centre, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden Erasmus MC Cancer Institute, University Medical Center Rotterdam, Department of Urology, Rotterdam, Netherlands College of Medicine and Public Health, Flinders University, Adelaide, Australia Department of Physics and Astronomy and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, Netherlands Department of Transfusion Medicine, University Hospital, Salzburger Landeskliniken GmbH of Paracelsus Medical University, Salzburg, Austria GMP Unit, Paracelsus Medical University, Salzburg, Austria Transfer Centre for Extracellular Vesicle Theralytic Technologies, EV-TT, Salzburg, Austria Expansion Therapeutics, Structural Biology and Biophysics, Jupiter, FL, United States Department of Anesthesiology & Perioperative Medicine, Oregon Health & Science University, Portland, OR, United States Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran Celer Diagnostics, Toronto, Canada Waipapa Taumata Rau University of Auckland, Auckland, New Zealand Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States Universidad de la República, Montevideo, Uruguay Institut Pasteur de Montevideo, Montevideo, Uruguay Biological Nanochemistry Research Group, Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Budapest, Hungary Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary Biomedical Engineering and Physics, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, Netherlands Laboratory of Experimental Clinical Chemistry, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, Netherlands Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands University of Denver, Denver, United States International Society for Extracellular Vesicles, Sweden Institut Curie, INSERM U932, PSL University, Paris, France CurieCoreTech Extracellular Vesicles, Institut Curie, Paris, France Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD, United States EV Core Facility “EXCEL”, Institute for Basic Biomedical Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States The Richman Family Precision Medicine Center of Excellence in Alzheimer’s Disease, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Molecular Medicine, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, CA, United States Department of Biochemistry, University of Toronto, Toronto, Canada University of Westminster, London, United Kingdom Egypt Center for Research and Regenerative Medicine, Cairo, Egypt Biotechnology Department, Faculty of Science, Cairo University, Cairo, Egypt Center of Excellence for Stem Cells and Regenerative Medicine, Zewail City for Science and Technology, Cairo, Egypt Brigham and Women’s Hospital, Boston, MA, United States Harvard Medical School, Boston, MA, United States Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom Kyoto University, Kyoto, Japan Division of Transplantation, Department of Surgery, University of Wisconsin, Madison, WI, United States Centre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Kuala Lumpur, Malaysia Department for Clinical Sciences and Community Health (DISCCO), University of Milan, Milan, Italy National Institute of Molecular Genetics (INGM), Milan, Italy Multiple Sclerosis Group, Biogipuzkoa Health Research Institute, San Sebastian, Spain Department of Pharmacology, University of Valencia, Spain Washington University School of Medicine, St. Louis, MO, United States Neurosurgery Department, Chris O’Brien Lifehouse, Camperdown, Australia Neuropathology Department, Royal Prince Alfred Hospital, Camperdown, Australia School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Australia Boise State University, Boise, ID, United States Azymus Therapeutics Inc., Boise, ID, United States University Health Network, Toronto, Canada Fraunhofer Institut for Cell Therapy and Immunology IZI, Leipzig, Germany BioMimetic Systems Engineering Laboratory, School of Chemical Engineering, Faculty of Engineering, Architecture and Information Technology, The University of Queensland, St Lucia, Australia Centre for Biomedical Technologies, School of Mechanical, Medical, and Process Engineering, Faculty of Engineering, Queensland University of Technology, Brisbane, Australia University of Sao Paulo, Ribeirao Preto Medical School, Sao Paulo, Brazil Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal Wake Forest School of Medicine, Winston-Salem, NC, United States National Institutes of Health, BethesdaMD, United States Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil Radiation Oncology Department, Barretos Cancer Hospital, Barretos, Brazil Immunology Department, IIS-Fundacion Jimenez Diaz, Fundacion Jimenez Diaz University Hospital-UAM, Madrid, Spain Department of Biochemistry and Molecular Biology, Complutense University, Madrid, Spain Instituto de Química y Fisicoquímica Biológicas “Prof. Alejandro C. Paladini”, Buenos Aires, Argentina Consejo Nacional de Investigaciones Científicas y Tecnicas, Argentina Facultad de Ciencias Exactas y Naturales, University of Buenos Aires, Buenos Aires, Argentina Department of Pathology, Gyeongsang National University Changwon Hospital, Changwon, South Korea lnstitute of Medical Sciences, Gyeongsang National University, Jinju, South Korea Department of Pathology, Gyeongsang National University School of Medicine, Jinju, South Korea Department of Chemical Pathology, School of Pathology, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden ME Cell Therapy and Allogenic Stem Cell Transplantation CAST, Karolinska University Hospital, Stockholm, Sweden University of California, Davis School of Medicine, Sacramento, CA, United States INSERM U1046, UMR CNRS 9214, University of Montpellier, Montpellier, France Inoviq Limited, Notting Hill, Australia FRACTAL—Flow Cytometry Resource, Advanced Cytometry Technical Applications Laboratory, IRCCS Ospedale San Raffaele Scientific Institute, Milan, Italy Università Vita-Salute San Raffaele, Milan, Italy Department for Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Center, Bonn, Germany German Center for Neurodegenerative Diseases, Bonn, Germany Department of Medicine, University of Louisville, Louisville, KY, United States Brown Cancer Center, University of Louisville, Louisville, KY, United States Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD, United States IVPC UMR754, INRAE, EPHE, Universite Claude Bernard Lyon 1, Lyon, France Faculté de Médecine, Université Laval, Quebec, Canada Centre de Recherche du Centre Hospitalier Universitaire de Québec, Université Laval, Quebec, Canada Centre de Recherche en Organogénèse Expérimentale de l’Université Laval/LOEX, Quebec, Canada Dartmouth Health, Lebanon, NH, United States Veterans Affairs Medical Center, White River JunctionVT, United States Experimental Rheumatology, Radboud University Medical Center, Nijmegen, Netherlands Mursla Ltd, Cambridge, United Kingdom Exosla Ltd, Cambridge, United Kingdom Laboratory on Thymus Research, Oswaldo Cruz Institute/Fiocruz, Rio de Janeiro, Brazil INSERM U1109, Strasbourg, France Center Research Biomedicine De Strasbourg, France Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Australia Vesiculab Ltd, Nottingham, United Kingdom Boston Medical Center, Boston, MA, United States School of Health Sciences, Universiti Sains Malaysia, George Town, Malaysia Johns Hopkins University School of Medicine, Baltimore, MD, United States University of Birmingham, Birmingham, United Kingdom INSERM U1266, Institute of Psychiatry and Neurosciences of Paris, Paris, France Oniris, INRAE, IECM, Nantes, France Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Department I of Internal Medicine, Faculty of Medicine, University of Cologne, University Hospital Cologne, Cologne, Germany CECAD Center of Excellence on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany Department of Life Sciences, Pohang University of Science and Technology, Pohang, South Korea Department of Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden Department of Clinical Immunology, Medical College, Jagiellonian University, Krakow, Poland Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States Center for Molecular Cardiology, University of Zurich, Zurich, Switzerland Laboratory of Cellular and Molecular Cardiology, Istituto Cardiocentro Ticino-EOC, Lugano, Switzerland Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, Netherlands Centre for Molecular Neurosciences, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, India Maharshi Dayanand University, Haryana, Rohtak, India Institut de Recherche Biomédicale des Armées, Brétigny sur Orge, France INSERM UMR-MD-1197, Clamart, France Centre de Transfusion des Armées, Clamart, France Institut de Recherche en Infectiologie de Montpellier (IRIM), UMR9004 CNRS, Montpellier, France University of Montpellier, Montpellier, France Cardiovascular Theranostics, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, Bellinzona, Switzerland Euler Institute, Faculty of Biomedical Sciences, Università Svizzera Italiana, Lugano, Switzerland Vanderbilt University School of Medicine, Nashville, TN, United States Department of Medicine and Animal Surgery, Veterinary Science, University of Murcia, Murcia, Spain Istituto Superiore di Sanità, Rome, Italy Developmental Biology Laboratory, Disease Networks RU, Faculty of Biochemistry and Molecular Medicine, University Oulu, Oulu, Finland Nazarbayev University, Astana, Kazakhstan Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy Department of Medical and Molecular Sciences, University of Delaware, Newark, DE, United States Frederick P. Whiddon College of Medicine, University of South Alabama, Mobile, AL, United States La Trobe University, Melbourne, Australia Axe de Recherche Maladies Infectieuses et Immunitaires, Centre de Recherche du CHU de Québec, Université Laval, Quebec, Canada Programme de Recherche sur les Maladies Infectieuses, Centre Muraz, Institut National de Santé Publique, Bobo-Dioulasso, Burkina Faso Department of Cardiac, Thoracic, Vascular Sciences and Public Health, Vascular Sciences and Public Health, University of Padua, Padua, Italy Department of Radiotherapy, GROW-School for Oncology and Reproduction, Maastricht University Medical Centre+, Maastricht, Netherlands Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany Amsterdam UMC, Amsterdam, Netherlands National Institute of Chemistry, Ljubljana, Slovenia Mayo Clinic Center for Clinical and Translational Science, Rochester, MN, United States Mayo Clinic Department of Cardiovascular Medicine, Jacksonville, FL, United States Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, United States Institute of Materials and Environmental Chemistry, Biomolecular Self-assembly Research Group, Reserach Centre for Natural Sciences, Budapest, Hungary Faculty of Medicine, Université Laval, Quebec, Canada CHU de Quebec Research Center, Quebec, Canada University Eye Clinic Maastricht, MHeNs School for Mental Health and Neuroscience, Maastricht University Medical Center+, Maastricht, Netherlands Faculty of Pharmaceutical Sciences, School of Health Sciences, University of Iceland, Reykjavik, Iceland Ospedale Santo Spirito, Pescara, Italy Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA, United States School of Biological Sciences, National Institute of Science Education and Research (NISER) Bhubaneswar, An OCC of Homi Bhabha National Institute, Odisha, India CSIR-Indian Institute of Chemical Biology, Kolkata, India Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, United States Wellesley College, Wellesley, MA, United States BRICBordeaux Institute of Oncology-Inserm U1312, University of Bordeaux, Bordeaux, France St. Jude Children’s Reseach Hospital, Memphis, TN, United States Le Bonheur Children’s Hospital, Memphis, TN, United States University of Tennessee Health Sciences Center, Memphis, TN, United States INSERM, Paris Center for Cardiovascular Research-ParCC, Université Paris Cité, Paris, France Erasmus MC, Rotterdam, Netherlands Department of Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, United States Centre de Recherche ARThrite (Arthrite Recherche Traitements) de l’Université Laval, Quebec, Canada Institut Femto-ST, CNRS, Université de Franche-Comté, Besançon, France Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom School of Medicine, University College Dublin, Dublin, Ireland Department of Experimental Medicine (DIMES), University of Genova, Genova, Italy IRCCS Ospedale Policlinico San Martino, Genova, Italy Cell-Tech HUB at Institute for Research and Biomedical Innovation, National Research Council of Italy (CNR), Palermo, Italy Department of Veterinary Medicine, University of Teramo, Teramo, Italy C2VN, INSERM 1263, INRAE 1260, Aix-Marseille University, Marseille, France University of Illinois at Urbana-Champaign, Urbana-Champaign, IL, United States Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana-Champaign, IL, United States REMAR-IVECAT Group, Germans Trias i Pujol Research Institute (IGTP) & Nephrology Department, University Hospital Germans Trias i Pujol (HUGTiP), Can Ruti Campus, Badalona, Spain Department of Cell Biology, Physiology and Immunology, Universitat de Barcelona (UB), Barcelona, Spain Oniris IECM Laboratory, INRAE, USC1383, Nantes, France Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy Sanford Burnham Prebys, La JollaCA, United States Concordia University, Montreal, Canada Paris-Cardiovascular Research Center, INSERM, Université Paris Cité, Paris, France Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, United States Department of Urology, University of California, Los Angeles, Los Angeles, CA, United States Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angelev, CA, United States McGill University, Montreal, Canada Department of Clinical Medicine, Aarhus University, Aarhus, Denmark Department of Biomedical Engineering, University of California, Davis, Davis, CA, United States III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany Martin Zeitz Centre for Rare Diseases, University Medical Center Hamburg-Eppendorf, Hamburg, Germany Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States Neurology Department, Experimental Research in Stroke and Inflammation (ERSI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany School of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland University of Galway, Galway, Ireland Molecular Neurogenetics Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States Center for Clinical and Translational Research, The Research Institute at Nationwide Children’s Hospital, Columbus, OH, United States Department of Surgery, Wexner Medical Center, The Ohio State University, Columbus, OH, United States University of Bordeaux, Pessac, France Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel Institute of Nanotechnology and Advanced Materials (BINA), Bar-Ilan University, Ramat-Gan, Israel Hermelin Brain Tumor Center, Henry Ford Health, Detroit, MI 48202, United States Consiglio Nazionale delle Ricerche—Istituto per lo Studio dei Materiali Nanostrutturati, Bologna, Italy University of Florida, Gainesville, FL, United States Mayo Clinic, Jacksonville, FL, United States Department of Experimental Medicine, University of Salento, Lecce, Italy University of Nebraska Medical Center, Omaha, NE, United States Institute of Immunology & Infection Research, University of Edinburgh, Edinburgh, United Kingdom Laboratory of Microscopic Image Analysis and Machine Learning, Hungarian Research Network (HUN-REN), Biological Research Centre, Szeged, Hungary Department of Immunology, University of Szeged, Szeged, Hungary School of Interdisciplinary Medicine, University of Szeged, Szeged, Hungary Russell H. Morgan Dept. of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University School of Medicine, Baltimore, MD, United States Cellular Imaging Section and Vascular Biology Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy INSERM U1231, Faculty of Medicine and Pharmacy, University of Bourgogne-Franche Comté, Dijon, France Cancer Research Program, Research Institute of the McGill University Health Centre, Montreal, Canada Gerald Bronfman Department of Oncology, McGill University, Montreal, Canada Department of Pathology, McGill University, Montreal, Canada Laureate Institute for Brain Research, Tulsa, OK, United States Vascular Biology Program, Boston Children’s Hospital, Boston, MA, United States Department of Surgery, Boston Children’s Hospital and Harvard Medical School, Boston, MA, United States HUN-REN Biological Research Centre, Szeged, Hungary Department of Medicine, University of Michigan, Ann Arbor, MI, United States Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden Centro de Innovación e Investigación Biomédica, Universidad de Los Andes, Santiago, Chile Centro de Biología Celular y Biomedicina, Universidad San Sebastián, Santiago, Chile University of Georgia, Athens, GA, United States i3SInstitute for Research and Innovation in Health, University of Porto, Porto, Portugal Universidad Loyola, Sevilla, Spain Department of Medical Sciences, University of Turin, Turin, Italy Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Napoli, Italy Department of Dentistry, Faculty of Health Sciences, Universidad Europea de Valencia, Valencia, Spain ISGlobal, Barcelona Institute for Global Health, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain IGTP, Germans Trias i Pujol Health Research Institute, Badalona, Spain CIBERINFEC, ISCIII-CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain Centro de Investigação Translacional em Oncologia, Instituto do Câncer do Estado de São Paulo, São Paulo, Brazil Comprehensive Center for Precision Oncology, Universidade de São Paulo, São Paulo, Brazil Evox Therapeutics Limited, Oxford, United Kingdom Department of Biological and Medical Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Oxford, United Kingdom Krantz Family Center for Cancer Research, Massachusetts General Hospital, Boston, MA, United States Department of Medicine, Harvard Medical School, Boston, MA, United States Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy Pasteur Institute Italy Fondazione Cenci Bolognetti, Rome, Italy Département des Effets Biologiques des Rayonnements, Institut de Recherche Biomédicale des Armées (IRBA), Bretigny sur orge, France Centro de Biología Celular y Biomedicina, Facultad de Medicina y Ciencia, Universidad San Sebastián, Santiago, Chile Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, Chile Department of Human Genetics, KU Leuven, Leuven, Belgium Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland Faculty of Medicine, University of Zurich, Zurich, Switzerland Faculty of Science, University of Zurich, Zurich, Switzerland AstraZeneca, Mölndal, Sweden Department of Obstetrics and Gynaecology, University of Auckland, New Zealand Hub for Extracellular Investigations, University of Auckland, New Zealand Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA, United States Department of Biomedical Sciences, Chung Shan Medical University, Taichung City, Taiwan Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States Institute of Nanoengineering and Microsystems, Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan Medical School of Nantong University, Nantong, China Guangzhou Medical University, Guangzhou, China Cancer Center, Faculty of Health Sciences, University of Macau, Taipa, Macau MOE Frontier Science Centre for Precision Oncology, University of Macau, Taipa, Macau Department of Reproduction Biology, Leibniz-Institute for Zoo and Wildlife Research (IZW), Berlin, Germany The University of Queensland, Brisbane, Australia The University of California, Los Angeles, Los Angeles, CA, United States Research Institute of McGill University Health Centre, Montreal, Canada Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Australia National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov, Moscow, Russian Federation University Hospital Essen, Essen, Germany Department of Biochemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Australia Department of Stem Cell and Regenerative Biotechnology, Molecular & Cellular Reprogramming Center, Institute of Advanced Regenerative Science, Konkuk University, Seoul, South Korea StemExOne Co., Ltd., Seoul, South Korea Department of Biomedical Engineering, Ulsan National Institute of Science and Technology, Ulsan, South Korea Center for Soft and Living Matter, Institute for Basic Science, Ulsan, South Korea Department of Thoracic and Cardiovascular Surgery, Korea University Guro Hospital, College of Medicine, Korea University, Seoul, South Korea Image Guided Precision Cancer Surgery Institute, Korea University, Seoul, South Korea MILCH and Novel Therapeutics Lab, Division of Epidemiology, Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, Cincinnati, OH, United States Jefferson Weinberg Center for ALS, Department of Neuroscience, Thomas Jefferson University, Philadelphia, PA, United States Exopharm Ltd, Melbourne, Australia Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, United Kingdom INSERM U932, Institut Curie Centre de Recherche, PSL Research University, Paris, France Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH, United States Comprehensive Cancer Center, The Ohio State University, Columbus, OH, United States Epithelial Biology Center, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States Department of Clinical Sciences and Community Health, University of Milano, Milan, Italy Pediatric Nephrology, Dialysis and Transplant Unit, Fondazione IRCCS Ca’ Granda-Ospedale Maggiore Policlinico, Milano, Italy CarMeN Laboratory, UMR INRAE 1397/INSERM 1060, University of Lyon, Lyon, France Universitat de Valencia, Valencia, Spain Farmacia María Luisa Bertomeu Navajas, Valencia, Spain Universidad Internacional de Valencia, Valencia, Spain Institut de Recherche en Cancérologie de Montpellier (IRCM), INSERM U1194, Nuclear Medicine Department, Institut régional du Cancer de Mo AB - Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year‐on‐year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non‐vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its ‘Minimal Information for Studies of Extracellular Vesicles’, which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly. LA - English DB - MTMT ER - TY - GEN AU - Kovács, Kinga Dóra AU - Visnovitz, Tamás AU - Kanyó, Nicolett AU - Gerecsei, Tamás AU - Péter, Beatrix AU - Lagzi, István AU - Kurunczi, Sándor AU - Koncz, Anna AU - Németh, Krisztina AU - Lenzinger, Dorina AU - V. Vukman, Krisztina AU - Molnár, Kinga AU - Truszka, Mónika AU - Nakanishi, Hideyuki AU - Lőrincz, Péter AU - Székács, Inna AU - Buzás, Edit I. AU - Horváth, Róbert TI - Nanoinjection of fluorescent and gold nanoparticles to single live cells by robotic fluidic force microscopy PY - 2023 UR - https://m2.mtmt.hu/api/publication/34486423 ID - 34486423 LA - English DB - MTMT ER - TY - CHAP AU - Kovács, Kinga Dóra AU - Visnovitz, Tamás AU - Gerecsei, Tamás AU - Péter, Beatrix AU - Kurunczi, Sándor AU - Koncz, Anna AU - Németh, Krisztina AU - Lenzinger, Dorina AU - V. Vukman, Krisztina AU - Lőrincz, Péter AU - Székács, Inna AU - Buzás, Edit I. AU - Horváth, Róbert ED - Derényi, Imre ED - László, Grama ED - Solymosi, Katalin TI - Nanoinjection of fluorescent nanoparticles to single live cells by robotic fluidic force microscopy T2 - Magyar Biofizikai Társaság XXIX. Kongresszusa PB - Magyar Biofizikai Társaság CY - Budapest SN - 9786150186887 PY - 2023 SP - 35 EP - 35 PG - 1 UR - https://m2.mtmt.hu/api/publication/34486404 ID - 34486404 LA - English DB - MTMT ER - TY - JOUR AU - Kovács, Kinga Dóra AU - Visnovitz, Tamás AU - Gerecsei, Tamás AU - Péter, Beatrix AU - Kurunczi, Sándor AU - Koncz, Anna AU - Németh, Krisztina AU - Lenzinger, Dorina AU - Visnovitzné Dr Vukman, Krisztina AU - Balogh, Anna AU - Rajmon, Imola AU - Lőrincz, Péter AU - Székács, Inna AU - Buzás, Edit Irén AU - Horváth, Róbert TI - Nanoinjection of extracellular vesicles to single live cells by robotic fluidic force microscopy JF - JOURNAL OF EXTRACELLULAR VESICLES J2 - J EXTRACELLULAR VESICL VL - 12 PY - 2023 IS - 12 PG - 16 SN - 2001-3078 DO - 10.1002/jev2.12388 UR - https://m2.mtmt.hu/api/publication/34425078 ID - 34425078 AB - In the past decade, extracellular vesicles (EVs) have attracted substantial interest in biomedicine. With progress in the field, we have an increasing understanding of cellular responses to EVs. In this Technical Report, we describe the direct nanoinjection of EVs into the cytoplasm of single cells of different cell lines. By using robotic fluidic force microscopy (robotic FluidFM), nanoinjection of GFP positive EVs and EV‐like particles into single live HeLa, H9c2, MDA‐MB‐231 and LCLC‐103H cells proved to be feasible. This injection platform offered the advantage of high cell selectivity and efficiency. The nanoinjected EVs were initially localized in concentrated spot‐like regions within the cytoplasm. Later, they were transported towards the periphery of the cells. Based on our proof‐of‐principle data, robotic FluidFM is suitable for targeting single living cells by EVs and may lead to information about intracellular EV cargo delivery at a single‐cell level. LA - English DB - MTMT ER -