TY - JOUR AU - Szikora, István AU - Magyar, Bence AU - Téglás, Sándor AU - Szudi, Gábor AU - Szalmás, Orsolya AU - Czencz, Máté AU - Kondor, Máté AU - Pozsár, Kinga AU - Nardai, Sándor AU - Erőss, Loránd AU - Óváry, Csaba AU - Horváth, Krisztina AU - Molnár, Ferenc József AU - Pápai, György AU - Jancsó, Ádám AU - Szabó, Zoltán AU - Benes, Edvárd AU - Chadaide, Zoltán TI - Mesterséges intelligencia alapú országos döntéstámogató rendszer bevezetése a hazai stroke-ellátás javítására JF - LEGE ARTIS MEDICINAE J2 - LEGE ART MED VL - 34 PY - 2024 IS - 3 SP - 145 EP - 152 PG - 8 SN - 0866-4811 DO - 10.33616/lam.34.0145 UR - https://m2.mtmt.hu/api/publication/34784264 ID - 34784264 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Schijns, Olaf E M G AU - Delev, Daniel AU - von Lehe, Marec AU - van Roost, Dirk AU - Rössler, Karl AU - Theys, Tom AU - Auer, Christian AU - Blauwblomme, Thomas AU - Budke, Marcelo AU - Campos, Alexandre Rainha AU - Canto, Santiago Candela AU - Clusmann, Hans AU - Dorfer, Christian AU - Dorfmüller, Georg AU - Egge, Arild AU - Erőss, Loránd AU - Ferrand-Sorbets, Sarah AU - Giordano, Flavio AU - Honegger, Jürgen AU - Isler, Cihan AU - Ivanovic, Jugoslav AU - Kalbhenn, Thilo AU - Karppinen, Atte AU - Krayenbühl, Niklaus AU - van Lanen, Rick H G J AU - Marras, Carlo E AU - Mavridis, Ioannis AU - Nilsson, Daniel AU - Onken, Julia AU - Raftopoulos, Christian AU - Roth, Jonathan AU - Rumia, Jordi AU - Sauvigny, Thomas AU - Scavarda, Didier AU - Schaller, Karl AU - Scheiwe, Christian AU - Schuind, Sophie AU - Seromenho-Santos, Alexandra AU - Fountas, Kostas TI - Functional hemispheric disconnection procedures for chronic epilepsy. history, indications, techniques, complications and current practice in Europe. A consensus statement on behalf of the EANS functional neurosurgery section. TS - history, indications, techniques, complications and current practice in Europe. A consensus statement on behalf of the EANS functional neurosurgery section. JF - BRAIN AND SPINE J2 - BRAIN SPINE VL - 4 PY - 2024 SN - 2772-5294 DO - 10.1016/j.bas.2024.102754 UR - https://m2.mtmt.hu/api/publication/34750108 ID - 34750108 AB - The surgical procedure for severe, drug-resistant, unilateral hemispheric epilepsy is challenging. Over the last decades the surgical landscape for hemispheric disconnection procedures changed from anatomical hemispherectomy to functional hemispherotomy with a reduction of complications and stable good seizure outcome. Here, a task force of European epilepsy surgeons prepared, on behalf of the EANS Section for Functional Neurosurgery, a consensus statement on different aspects of the hemispheric disconnection procedure.To determine history, indication, timing, techniques, complications and current practice in Europe for hemispheric disconnection procedures in drug-resistant epilepsy.Relevant literature on the topic was collected by a literature search based on the PRISMA 2020 guidelines.A comprehensive overview on the historical development of hemispheric disconnection procedures for epilepsy is presented, while discussing indications, timing, surgical techniques and complications. Current practice for this procedure in European epilepsy surgery centers is provided. At present, our knowledge of long-term seizure outcomes primarily stems from open surgical disconnection procedures. Although minimal invasive surgical techniques in epilepsy are rapidly developing and reported in case reports or small case series, long-term seizure outcome remain uncertain and needs to be reported.This is the first paper presenting a European consensus statement regarding history, indications, techniques and complications of hemispheric disconnection procedures for different causes of chronic, drug-resistant epilepsy. Furthermore, it serves as the pioneering document to report a comprehensive overview of the current surgical practices regarding this type of surgery employed in renowned epilepsy surgery centers across Europe. LA - English DB - MTMT ER - TY - JOUR AU - Erőss, Loránd AU - Halász, László AU - Miklós, Gabriella TI - Az intra- és perioperatív képalkotás lehetőségei az idegsebészetben JF - MAGYAR ONKOLÓGIA J2 - MAGYAR ONKOLÓGIA VL - 68 PY - 2024 IS - 1 SP - 5 EP - 12 PG - 8 SN - 0025-0244 UR - https://m2.mtmt.hu/api/publication/34727535 ID - 34727535 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Szalárdy, Orsolya AU - Simor, Péter Dániel AU - Ujma, Przemyslaw Péter AU - Jordán, Zsófia AU - Halász, László AU - Erőss, Loránd AU - Fabó, Dániel AU - Bódizs, Róbert TI - Temporal association between sleep spindles and ripples in the human anterior and mediodorsal thalamus JF - EUROPEAN JOURNAL OF NEUROSCIENCE J2 - EUR J NEUROSCI VL - 59 PY - 2024 IS - 4 SP - 641 EP - 661 PG - 21 SN - 0953-816X DO - 10.1111/ejn.16240 UR - https://m2.mtmt.hu/api/publication/34505166 ID - 34505166 AB - Sleep spindles are major oscillatory components of Non-Rapid Eye Movement (NREM) sleep, reflecting hyperpolarization-rebound sequences of thalamocortical neurons. Reports suggest a link between sleep spindles and several forms of high-frequency oscillations which are considered as expressions of pathological off-line neural plasticity in the central nervous system. Here we investigated the relationship between thalamic sleep spindles and ripples in the anterior and mediodorsal nuclei (ANT and MD) of epilepsy patients. Whole-night LFP from the ANT and MD were co-registered with scalp EEG/polysomnography by using externalized leads in 15 epilepsy patients undergoing a Deep Brain Stimulation protocol. Slow (~12 Hz) and fast (~14 Hz) sleep spindles were present in the human ANT and MD and roughly, 20% of them were associated with ripples. Ripple-associated thalamic sleep spindles were characterized by longer duration and exceeded pure spindles in terms of spindle power as indicated by time-frequency analysis. Furthermore, ripple amplitude was modulated by the phase of sleep spindles within both thalamic nuclei. No signs of pathological processes were correlated with measures of ripple and spindle association, furthermore, the density of ripple-associated sleep spindles in the ANT showed a positive correlation with verbal comprehension. Our findings indicate the involvement of the human thalamus in coalescent spindle-ripple oscillations of NREM sleep. LA - English DB - MTMT ER - TY - JOUR AU - Várkuti, Bálint AU - Halász, László AU - Hagh Gooie, Saman AU - Miklós, Gabriella AU - Smits Serena, Ricardo AU - van Elswijk, Gijs AU - McIntyre, Cameron C AU - Lempka, Scott F AU - Lozano, Andres M AU - Erőss, Loránd TI - Conversion of a medical implant into a versatile computer-brain interface. JF - BRAIN STIMULATION J2 - BRAIN STIMUL VL - 17 PY - 2024 IS - 1 SP - 39 EP - 48 PG - 10 SN - 1935-861X DO - 10.1016/j.brs.2023.12.011 UR - https://m2.mtmt.hu/api/publication/34473853 ID - 34473853 AB - Information transmission into the human nervous system is the basis for a variety of prosthetic applications. Spinal cord stimulation (SCS) systems are widely available, have a well documented safety record, can be implanted minimally invasively, and are known to stimulate afferent pathways. Nonetheless, SCS devices are not yet used for computer-brain-interfacing applications.Here we aimed to establish computer-to-brain communication via medical SCS implants in a group of 20 individuals who had been operated for the treatment of chronic neuropathic pain.In the initial phase, we conducted interface calibration with the aim of determining personalized stimulation settings that yielded distinct and reproducible sensations. These settings were subsequently utilized to generate inputs for a range of behavioral tasks. We evaluated the required calibration time, task training duration, and the subsequent performance in each task.We could establish a stable spinal computer-brain interface in 18 of the 20 participants. Each of the 18 then performed one or more of the following tasks: A rhythm-discrimination task (n = 13), a Morse-decoding task (n = 3), and/or two different balance/body-posture tasks (n = 18; n = 5). The median calibration time was 79 min. The median training time for learning to use the interface in a subsequent task was 1:40 min. In each task, every participant demonstrated successful performance, surpassing chance levels.The results constitute the first proof-of-concept of a general purpose computer-brain interface paradigm that could be deployed on present-day medical SCS platforms. LA - English DB - MTMT ER - TY - JOUR AU - Sákovics, Anna AU - Csukly, Gábor AU - Virág, Márta AU - Borbély, Csaba AU - Kelemen, Anna AU - Erőss, Loránd AU - Fabó, Dániel TI - Prolongation of cortical sleep spindles during hippocampal interictal epileptiform discharges in epilepsy patients JF - EUROPEAN JOURNAL OF NEUROLOGY J2 - EUR J NEUROL VL - 30 PY - 2023 SP - 624 EP - 625 PG - 2 SN - 1351-5101 UR - https://m2.mtmt.hu/api/publication/34428820 ID - 34428820 LA - English DB - MTMT ER - TY - GEN AU - Nagy, Gábor AU - Horváth, Barnabás AU - Szalóki, Tibor AU - Varga, Zsuzsa AU - Forgács, Gábor AU - Entz, László AU - Benkő, Zsolt AU - Orbay, Péter AU - Markia, Balázs AU - Sipos, László AU - Erőss, Loránd AU - Reisch, Róbert TI - A hipofízis daganatok sebészi kezelési lehetőségei : Endoszkópos transznazális műtét PY - 2023 UR - https://m2.mtmt.hu/api/publication/34428107 ID - 34428107 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Mező, A. AU - Bokor, Magdolna AU - Balogh, Eszter AU - Halász, László AU - Erőss, Loránd TI - The duration of Intrathecal Baclofen Therapy in MS patients – more than 20 years follow up JF - EUROPEAN JOURNAL OF NEUROLOGY J2 - EUR J NEUROL VL - 30 PY - 2023 IS - Suppl. 1 SP - 830 SN - 1351-5101 UR - https://m2.mtmt.hu/api/publication/34425267 ID - 34425267 LA - English DB - MTMT ER - TY - GEN AU - Szikora, István AU - Pápai, György AU - Radnai, Mónika AU - Kondor, Máté AU - Czencz, Máté AU - Nardai, Sándor AU - Óváry, Csaba AU - Erőss, Loránd TI - Mesterséges intelligencia alapú döntéstámogató rendszer hatása az akut stroke betegek beszállítási idejére PY - 2023 UR - https://m2.mtmt.hu/api/publication/34192725 ID - 34192725 LA - Hungarian DB - MTMT ER - TY - GEN AU - Szikora, István AU - Magyar, Bence AU - Szudi, Gábor AU - Kondor, Máté AU - Czencz, Máté AU - Pozsár, Kinga AU - Nardai, Sándor AU - Chadaide, Zoltán AU - Benes, Edvárd AU - Jancsó, Ádám AU - Szabó, Zoltán AU - Óváry, Csaba AU - Erőss, Loránd TI - Mesterséges intelligencia alapú országos döntéstámogató rendszer a hazai stroke ellátás javítására PY - 2023 UR - https://m2.mtmt.hu/api/publication/34192608 ID - 34192608 LA - Hungarian DB - MTMT ER -