@article{MTMT:34523817,
	title = {Tumour regression predicts better response to interferon therapy in melanoma patients. a retrospective single centre study.},
	url = {https://m2.mtmt.hu/api/publication/34523817},
	author = {Mezőlaki, Noémi and Baltás, Eszter and Ócsai, Henriette and Varga, Anita and Korom, Irma and Varga, Erika and Németh, István Balázs and Kis, Erika and Varga, János and Kocsis, Ádám László and Gyulai, Rolland Péter and Bukva, Mátyás and Kemény, Lajos and Oláh, Judit Magdolna},
	doi = {10.1097/CMR.0000000000000935},
	journal-iso = {MELANOMA RES},
	journal = {MELANOMA RESEARCH},
	volume = {34},
	unique-id = {34523817},
	issn = {0960-8931},
	abstract = {We hypothesise that regression may have an impact on the effectiveness of adjuvant IFN therapy, based on its role in the host immune response. Our purpose is to investigate regression and ulceration as prognostic factors in case of interferon-alpha (IFN)-treated melanoma patients. We followed 357 IFN-treated melanoma patients retrospectively, investigating progression-free survival (PFS) and overall survival (OS) depending on the presence of ulceration and regression. A Kaplan-Meier analysis was performed, and we used a Cox regression analysis to relate risk factors. The survival function of the Cox regression was used to measure the effect of regression and ulceration on PFS and OS depending on the Breslow thickness (T1-T4) of the primary tumour. Regression was significantly positively related to PFS ( P  = 0.0018, HR = 0.352) and OS ( P  = 0.0112, HR = 0.380), while ulceration showed a negative effect (PFS: P  = 0.0001, HR = 2.629; OS: P  = 0.0003, HR = 2.388). They influence survival independently. The most favourable outcome was measured in the regressed/non-ulcerated group, whereas the worse was in the non-regressed/ulcerated one. Of risk factors, Breslow thickness is the most significant predictor. The efficacy of regression is regardless of Breslow thickness, though the more favourable the impact of regression was in the thicker primary lesions. Our results indicate that regression is associated with a more favourable outcome for IFN-treated melanoma patients, whereas ulceration shows an inverse relation. Further studies are needed to analyse the survival benefit of regression in relation to innovative immune checkpoint inhibitors.},
	year = {2024},
	eissn = {1473-5636},
	pages = {54-62},
	orcid-numbers = {Baltás, Eszter/0000-0003-0357-7393; Gyulai, Rolland Péter/0000-0002-3286-8846; Bukva, Mátyás/0000-0002-5225-0285; Kemény, Lajos/0000-0002-2119-9501}
}

@article{MTMT:34513890,
	title = {Sarcoid-like reakciók előfordulása metasztatikus melanoma miatt immunterápiával kezelt betegnél},
	url = {https://m2.mtmt.hu/api/publication/34513890},
	author = {Hánis, Csilla and Csányi, Ildikó and Ócsai, Henriette and Németh, István Balázs and Bende, Balázs and Besenyi, Zsuzsanna and Hideghéty, Katalin and Kemény, Lajos and Gyulai, Rolland Péter and Oláh, Judit Magdolna and Baltás, Eszter},
	journal-iso = {BVSZ},
	journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE},
	volume = {99},
	unique-id = {34513890},
	issn = {0006-7768},
	year = {2023},
	eissn = {2064-261X},
	pages = {438-438},
	orcid-numbers = {Csányi, Ildikó/0000-0002-0766-5289; Besenyi, Zsuzsanna/0000-0001-9115-9620; Hideghéty, Katalin/0000-0001-7080-2365; Kemény, Lajos/0000-0002-2119-9501; Gyulai, Rolland Péter/0000-0002-3286-8846; Baltás, Eszter/0000-0003-0357-7393}
}

@article{MTMT:34443653,
	title = {Elevated serum gastrin is associated with melanoma progression: putative role in increased migration and invasion of melanoma cells},
	url = {https://m2.mtmt.hu/api/publication/34443653},
	author = {Varga, Ákos and Németh, István Balázs and Kemény, Lajos and Varga, János and Tiszlavicz, László and Kumar, D. and Dodd, S. and Simpson, A.W.M. and Buknicz, Tünde and Beynon, R. and Simpson, D. and Krenács, Tibor and Dockray, G.J. and Varro, A.},
	doi = {10.3390/ijms242316851},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {24},
	unique-id = {34443653},
	issn = {1661-6596},
	year = {2023},
	eissn = {1422-0067},
	orcid-numbers = {Kemény, Lajos/0000-0002-2119-9501; Tiszlavicz, László/0000-0003-1134-6587; Krenács, Tibor/0000-0001-9164-065X}
}

@misc{MTMT:34437156,
	title = {Six potential proteins predicting immune checkpoint therapy response in three independent metastatic melanoma cohorts},
	url = {https://m2.mtmt.hu/api/publication/34437156},
	author = {Szadai, Leticia and Bartha, Áron and Parada, Pla Indira and Lakatos, Alexandra and Pál, Dorottya and Lengyel, Sára Anna and Almeida, Natália and Jánosi, Ágnes Judit and Nogueira, Fábio and Szeitz, Beáta and Doma, Viktória and Woldmar, Nicole and Guedes, Jéssica and Újfaludi, Zsuzsanna and Kim, Yonghyo and Páhi, Gábor Zoltán and Pankotai, Tibor and Győrffy, Balázs and Ingvar, C and Ekedahl, H and Jundgren, L and Baldetorp, B and Welinder, C and Szász, Marcell and Betancourt, Lazaro and Gil, Jeovanis and Appelqvist, Roger and Kwon, Jeong and Kárpáti, Sarolta and Németh, István Balázs and Malm, Johan and Fenyő, Dávid and Pawlowski, Krzysztof and Horvatovich, Péter and Wieslander, Elisabet and Marko-Varga, György and Kemény, Lajos Vince and Domont, Gilberto and Sanchez, Aniel},
	unique-id = {34437156},
	year = {2023},
	orcid-numbers = {Újfaludi, Zsuzsanna/0000-0003-4738-0963; Pankotai, Tibor/0000-0001-9810-5465}
}

@article{MTMT:34437117,
	title = {Quantitative proteomics on laser microdissected early-stage melanomas reveals a mitochondrial involvement in the disease progression},
	url = {https://m2.mtmt.hu/api/publication/34437117},
	author = {Szadai, Leticia and Guedes, Jessica and Gil, Jeovanis and Marko-Varga, György and Németh, István Balázs},
	journal-iso = {ARCH HUNG MED ASSOC AM},
	journal = {ARCHIVES OF THE HUNGARIAN MEDICAL ASSOCIATION OF AMERICA},
	volume = {29},
	unique-id = {34437117},
	issn = {1070-0773},
	year = {2023},
	pages = {36-36}
}

@article{MTMT:34436978,
	title = {Mitochondrial and immune response dysregulation in melanoma recurrence},
	url = {https://m2.mtmt.hu/api/publication/34436978},
	author = {Szadai, Leticia and Guedes, Jéssica de Siqueira and Woldmar, Nicole and de Almeida, Natália Pinto and Jánosi, Ágnes Judit and Rajeh, Ahmad and Kovács, Ferenc and Kriston, András and Migh, Ede and Wan, Guihong and Nguyen, Nga and Oskolás, Henriett and Appelqvist, Roger and Nogueira, Fábio Cn and Domont, Gilberto B and Yu, Kun-Hsing and Semenov, Eugene R and Malm, Johan and Rezeli, Melinda and Wieslander, Elisabet and Fenyö, David and Kemény, Lajos and Horváth, Péter and Németh, István Balázs and Marko-Varga, György and Gil, Jeovanis},
	doi = {10.1002/ctm2.1495},
	journal-iso = {CLIN TRANSL MED},
	journal = {CLINICAL AND TRANSLATIONAL MEDICINE},
	volume = {13},
	unique-id = {34436978},
	issn = {2001-1326},
	year = {2023},
	eissn = {2001-1326},
	orcid-numbers = {Kemény, Lajos/0000-0002-2119-9501}
}

@article{MTMT:34068499,
	title = {Does Diffusely Infiltrating Lobular Carcinoma of the Breast Arise from Epithelial-Mesenchymal Hybrid Cells?},
	url = {https://m2.mtmt.hu/api/publication/34068499},
	author = {Tabár, László and Bozó, Renáta and Dean, Peter B and Ormándi, Katalin and Puchkova, Olga and Oláh, Orsolya and Németh, István Balázs and Veréb, Zoltán and Yen, Ming-Fang and Chen, Li-Sheng and Chen, Hsiu-Hsi and Vörös, András},
	doi = {10.3390/ijms241310752},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {24},
	unique-id = {34068499},
	issn = {1661-6596},
	abstract = {Classic diffusely infiltrating lobular carcinoma has imaging features divergent from the breast cancers originating from the terminal ductal lobular units and from the major lactiferous ducts. Although the term "invasive lobular carcinoma" implies a site of origin within the breast lobular epithelium, we were unable to find evidence supporting this assumption. Exceptional excess of fibrous connective tissue and the unique cell architecture combined with the aberrant features at breast imaging suggest that this breast malignancy has not originated from cells lining the breast ducts and lobules. The only remaining relevant component of the fibroglandular tissue is the mesenchyme. The cells freshly isolated and cultured from diffusely infiltrating lobular carcinoma cases contained epithelial-mesenchymal hybrid cells with both epithelial and mesenchymal properties. The radiologic and histopathologic features of the tumours and expression of the mesenchymal stem cell positive markers CD73, CD90, and CD105 all suggest development in the direction of mesenchymal transition. These hybrid cells have tumour-initiating potential and have been shown to have poor prognosis and resistance to therapy targeted for malignancies of breast epithelial origin. Our work emphasizes the need for new approaches to the diagnosis and therapy of this highly fatal breast cancer subtype.},
	keywords = {Biomarkers; Breast Neoplasms; interdisciplinary communication; patient care; Mammography; Early Detection of Cancer; PATHOLOGISTS; precision oncology; neoplastic stem cell; Histopathology technology},
	year = {2023},
	eissn = {1422-0067},
	orcid-numbers = {Bozó, Renáta/0000-0003-4242-2474; Oláh, Orsolya/0000-0002-5731-4030; Veréb, Zoltán/0000-0002-9518-2155; Vörös, András/0000-0001-6837-0567}
}

@article{MTMT:33928967,
	title = {Biológiai és célzott terápiák bőrpathologiai vonatkozásai a mindennapi gyakorlatban},
	url = {https://m2.mtmt.hu/api/publication/33928967},
	author = {Varga, Erika and Horváth, Zsófia and Németh, István Balázs and Korom, Irma},
	doi = {10.7188/bvsz.2023.99.2.7},
	journal-iso = {BVSZ},
	journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE},
	volume = {99},
	unique-id = {33928967},
	issn = {0006-7768},
	year = {2023},
	eissn = {2064-261X},
	pages = {125-131}
}

@article{MTMT:33928935,
	title = {Az SZTE Bőrgyógyászati és Allergológiai Klinikán a melanoma malignum sebészi kezelésében történt változások az elmúlt évtizedben [Changes in the surgical treatment of melanoma malignum at the Department of Dermatology and Allergology University of Szeged over the last decade]},
	url = {https://m2.mtmt.hu/api/publication/33928935},
	author = {Varga, Ákos and Bende, Balázs and Baltás, Eszter and Németh, István Balázs and Varga, Erika and Vass, Gábor and Kis, Erika and Oláh, Judit Magdolna and Varga, János and Kocsis, Ádám László},
	doi = {10.7188/bvsz.2023.99.2.6},
	journal-iso = {BVSZ},
	journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE},
	volume = {99},
	unique-id = {33928935},
	issn = {0006-7768},
	year = {2023},
	eissn = {2064-261X},
	pages = {122-124},
	orcid-numbers = {Baltás, Eszter/0000-0003-0357-7393; Vass, Gábor/0000-0003-0787-8679}
}

@article{MTMT:33927401,
	title = {Morphologic variants of cell cannibalism in the spontaneous human melanoma-fibroblast hybrids using high-content fluorescent microscope imaging},
	url = {https://m2.mtmt.hu/api/publication/33927401},
	author = {Germán, P. and Veréb, Zoltán and Bozó, Renáta and Flink, Lili Borbála and Erdei, Lilla and Groma, Gergely and Szebeni, Gábor and Csörgő Sándorné Bata, Zsuzsanna and Kemény, Lajos and Németh, István Balázs},
	doi = {10.1016/j.jid.2023.03.1290},
	journal-iso = {J INVEST DERMATOL},
	journal = {JOURNAL OF INVESTIGATIVE DERMATOLOGY},
	volume = {143},
	unique-id = {33927401},
	issn = {0022-202X},
	year = {2023},
	eissn = {1523-1747},
	pages = {S219-S219},
	orcid-numbers = {Veréb, Zoltán/0000-0002-9518-2155; Bozó, Renáta/0000-0003-4242-2474; Erdei, Lilla/0000-0001-8129-2364; Groma, Gergely/0000-0001-8487-0465; Szebeni, Gábor/0000-0002-6998-5632; Csörgő Sándorné Bata, Zsuzsanna/0000-0002-3732-1743; Kemény, Lajos/0000-0002-2119-9501}
}