@article{MTMT:31788019,
	title = {Protective effects of the novel amine-oxidase inhibitor multi-target drug SZV 1287 on streptozotocin-induced beta cell damage and diabetic complications in rats},
	url = {https://m2.mtmt.hu/api/publication/31788019},
	author = {Tékus, Valéria and Horváth, Ádám István and Csekő, Kata and Szabadfi, Krisztina and Kovács-Valasek, Andrea and Dányádi, Bese and Deres, László and Halmosi, Róbert and Sághy, Éva and Varga, Zoltán and Adeghate, Ernest Akingunola and Kőszegi, Tamás and Mátyus, Péter and Gábriel, Róbert and Ferdinandy, Péter and Pintér, Erika and Helyes, Zsuzsanna},
	doi = {10.1016/j.biopha.2020.111105},
	journal-iso = {BIOMED PHARMACOTHER},
	journal = {BIOMEDICINE & PHARMACOTHERAPY},
	volume = {134},
	unique-id = {31788019},
	issn = {0753-3322},
	year = {2021},
	eissn = {1950-6007},
	orcid-numbers = {Sághy, Éva/0000-0002-4031-3461; Varga, Zoltán/0000-0002-2758-0784; Mátyus, Péter/0000-0003-3963-9445; Gábriel, Róbert/0000-0001-9323-8795; Ferdinandy, Péter/0000-0002-6424-6806; Pintér, Erika/0000-0001-9898-632X}
}

@mastersthesis{MTMT:30549982,
	title = {ANESZTETIKUS PREKONDÍCIONÁLÁS ÉS A VIP/PACAP PEPTIDCSALÁD VÉDŐ SZEREPÉNEK VIZSGÁLATA ISZKÉMIÁS RETINOPÁTIÁBAN},
	url = {https://m2.mtmt.hu/api/publication/30549982},
	author = {Dányádi, Bese},
	unique-id = {30549982},
	year = {2018}
}

@inbook{MTMT:3134694,
	title = {Protective Effects of PACAP in the Retina},
	url = {https://m2.mtmt.hu/api/publication/3134694},
	author = {Atlasz, Tamás and Váczy, Alexandra and Werling, Dóra and Kiss, Péter and Tamás, Andrea and Kovács, Krisztina and Fábián, Eszter and Kvárik, Tímea and Mammel, Barbara and Dányádi, Bese and Lőkös, Emese and Reglődi, Dóra},
	booktitle = {Pituitary Adenylate Cyclase Activating Polypeptide — PACAP},
	doi = {10.1007/978-3-319-35135-3_30},
	unique-id = {3134694},
	year = {2016},
	pages = {501-527},
	orcid-numbers = {Atlasz, Tamás/0000-0002-8112-8633}
}

@article{MTMT:3127952,
	title = {Ocular delivery of PACAP1-27 protects the retina from ischemic damage in rodents},
	url = {https://m2.mtmt.hu/api/publication/3127952},
	author = {Werling, Dóra and Reglődi, Dóra and Banks, William A and Salameh, Theresa S and Kovács, Krisztina and Kvárik, Tímea and Váczy, Alexandra and Kovács, László Ákos and Mayer, Flora and Dányádi, Bese and Lőkös, Emese and Tamás, Andrea and Tóth, Gábor and Biró, Zsolt and Atlasz, Tamás},
	doi = {10.1167/iovs.16-20630},
	journal-iso = {INVEST OPHTH VIS SCI},
	journal = {INVESTIGATIVE OPHTHALMOLOGY AND VISUAL SCIENCE},
	volume = {57},
	unique-id = {3127952},
	issn = {0146-0404},
	abstract = {Purpose: Pituitary adenylate cyclase activating polypeptide (PACAP) is neuroprotective in neuronal injuries. Bilateral common carotid artery occlusion (BCCAO) causes chronic hypoperfusion-induced degeneration in the rat retina, where we proved the retinoprotective effect of intravitreal PACAP. Although this route of administration is a common clinical practice in several diseases, easier routes are clinically important. Our aim was to investigate the potential retinoprotective effects of PACAP eye drops in BCCAO-induced ischemic retinopathy.
		
		Methods: After performing BCCAO in rats, the right eyes were treated with PACAP1-27 eye drops (1 μg/drop, 2 × 1 drops/day for 5 days), containing different vehicles: saline, water for injections, thiomersal or benzalkonium solution for ophthalmic use (SOCB). Histology and immunohistochemistry were performed 2 weeks after surgery, while molecular analysis was performed 24 hours after BCCAO. Passage of PACAP1-27 through the ocular layers was tested with radioactive PACAP-SOCB in mice.
		
		Results: Bilateral common carotid artery occlusion led to a severe degeneration of all retinal layers. Solution for ophthalmic use was the most effective vehicle for delivering PACAP (PACAP-SOCB), significantly ameliorating BCCAO-induced damage. The massive upregulation of GFAP was not observed in retinas treated with PACAP-SOCB eye drops. PACAP-SOCB treatment also increased activation of the protective Akt and ERK1/2 in hypoperfused retinas. The cytokine profile showing upregulation in different cytokines was attenuated by PACAP-SOCB. Radioactive PACAP reached the retina when delivered in SOCB-containing eye drops.
		
		Conclusions: PACAP1-27, delivered in the SOCB vehicle as eye drops, was retinoprotective in ischemic retinopathy, providing the basis for future therapeutic administration.},
	year = {2016},
	eissn = {1552-5783},
	pages = {6683-6691},
	orcid-numbers = {Tóth, Gábor/0000-0002-3604-4385; Atlasz, Tamás/0000-0002-8112-8633}
}

@article{MTMT:2580369,
	title = {PACAP Application Improves Functional Outcome of Chronic Retinal Ischemic Injury in Rats-Evidence From Electroretinographic Measurements},
	url = {https://m2.mtmt.hu/api/publication/2580369},
	author = {Dányádi, Bese and Szabadfi, Krisztina and Reglődi, Dóra and Mihalik, A and Danyadi, T and Kovács, Zsolt and Bátai, István and Tamás, Andrea and Kiss, Péter and Tóth, Gábor and Gábriel, Róbert},
	doi = {10.1007/s12031-014-0296-5},
	journal-iso = {J MOL NEUROSCI},
	journal = {JOURNAL OF MOLECULAR NEUROSCIENCE},
	volume = {54},
	unique-id = {2580369},
	issn = {0895-8696},
	abstract = {Retinoprotective effects of pituitary adenylate cyclase activating polypeptide (PACAP) are well-known and have been demonstrated in various pathological conditions, such as diabetic retinopathy, excitotoxic retinal injury, UV light-induced degeneration, and ischemic retinal lesion. The neuronal degeneration observed in the different retinal layers under the above pathological conditions can be successfully decreased by PACAP; however, whether this morphological improvement is also reflected in functional amelioration remains unknown. Therefore, our purpose was to investigate the protective effect of PACAP on the rat retina after bilateral common carotid artery occlusion (BCCAO) with electroretinography (ERG) to parallel the functional data with the previous morphological and neurochemical observations. Control eyes received saline treatment while PACAP was injected into the vitreous space of the other eye immediately after the induction of ischemia. Retinal damage and protective effects of PACAP were quantified by the changes in the wave forms and amplitudes. On postoperative days 2 and 14, several parameters were assessed with special attention to the changes of b wave. The results confirm that the previously described morphological protection induced by PACAP treatment is reflected in functional improvement in ischemic retinal lesions.},
	year = {2014},
	eissn = {1559-1166},
	pages = {293-299},
	orcid-numbers = {Kovács, Zsolt/0000-0001-8571-5686; Tóth, Gábor/0000-0002-3604-4385; Gábriel, Róbert/0000-0001-9323-8795}
}

@article{MTMT:2324166,
	title = {Urocortin 2 treatment is protective in excitotoxic retinal degeneration},
	url = {https://m2.mtmt.hu/api/publication/2324166},
	author = {Szabadfi, Krisztina and Kiss, Péter and Reglődi, Dóra and Fekete, EM and Tamás, Andrea and Dányádi, Bese and Atlasz, Tamás and Gábriel, Róbert},
	doi = {10.1556/APhysiol.100.2013.020},
	journal-iso = {ACTA PHYSIOL HUNG},
	journal = {ACTA PHYSIOLOGICA HUNGARICA},
	volume = {101},
	unique-id = {2324166},
	issn = {0231-424X},
	year = {2014},
	eissn = {1588-2683},
	pages = {67-76},
	orcid-numbers = {Atlasz, Tamás/0000-0002-8112-8633; Gábriel, Róbert/0000-0001-9323-8795}
}

@article{MTMT:2594513,
	title = {Functional protective effect of PACAP on chronic retinal ischemic injury in rats – electroretinographic measurements},
	url = {https://m2.mtmt.hu/api/publication/2594513},
	author = {Dányádi, Bese and Szabadfi, Krisztina and Mihalik, Á and Dányádi, T and Kovács, Zsolt and Gábriel, Róbert and Tamás, Andrea and Bátai, István and Tóth, G and Reglődi, Dóra},
	journal-iso = {J MOL NEUROSCI},
	journal = {JOURNAL OF MOLECULAR NEUROSCIENCE},
	volume = {51},
	unique-id = {2594513},
	issn = {0895-8696},
	year = {2013},
	eissn = {1559-1166},
	pages = {S229-S230},
	orcid-numbers = {Kovács, Zsolt/0000-0001-8571-5686; Gábriel, Róbert/0000-0001-9323-8795}
}

@CONFERENCE{MTMT:2562608,
	title = {Preconditioning with volatile anesthetics in ischemic retinal lesion in rats},
	url = {https://m2.mtmt.hu/api/publication/2562608},
	author = {Dányádi, Bese and Szabadfi, Krisztina and Reglődi, D and Gábriel, Róbert and Manavalan, S and Trásy, D and Bátai, István},
	booktitle = {IBRO International Workshop 2012},
	unique-id = {2562608},
	year = {2012},
	orcid-numbers = {Gábriel, Róbert/0000-0001-9323-8795}
}

@misc{MTMT:2562603,
	title = {Ischemia-induced retinal degeneration and neuroprotection mediated by various strategies},
	url = {https://m2.mtmt.hu/api/publication/2562603},
	author = {Szabadfi, Krisztina and Kiss, P and Reglődi, D and Dányádi, Bese and Kovács, K and Szabó, A and Sümegi, B and Vécsei, L and Bátai, István and Fekete, ÉM and Bari, F and Tamás, A and Atlasz, Tamás and Babai, N and Gábriel, Róbert},
	unique-id = {2562603},
	year = {2012},
	orcid-numbers = {Atlasz, Tamás/0000-0002-8112-8633; Gábriel, Róbert/0000-0001-9323-8795}
}

@CONFERENCE{MTMT:2562587,
	title = {Effects of PACAP on signaling pathways in the retina exposed to oxidative stress or ischemia},
	url = {https://m2.mtmt.hu/api/publication/2562587},
	author = {Reglodi, D and Fabian, E and Szabo, A and Szabadfi, Krisztina and Gábriel, Róbert and Kiss, P and Dányádi, Bese and Tamas, A and Toth, G and Mester, L and Kovacs, K},
	booktitle = {BPS Focused Meeting on Neuropeptides},
	unique-id = {2562587},
	year = {2012},
	orcid-numbers = {Gábriel, Róbert/0000-0001-9323-8795}
}