TY - THES AU - Pataki, Andrea Csilla TI - The isolation of new tissue polarity genes in Drosophila and the genetic analysis of Rab23 involved in the regulation of the number and planar organization of the adult cuticular hairs PB - Szegedi Tudományegyetem (SZTE) PY - 2010 SP - 107 UR - https://m2.mtmt.hu/api/publication/30773719 ID - 30773719 LA - English DB - MTMT ER - TY - JOUR AU - Pataki, Andrea Csilla AU - Matusek, Tamás AU - Kurucz, Judit Éva AU - Andó, István AU - Jenny, A AU - Mihály, József TI - Drosophila Rab23 Is Involved in the Regulation of the Number and Planar Polarization of the Adult Cuticular Hairs JF - GENETICS J2 - GENETICS VL - 184 PY - 2010 IS - 4 SP - 1051 EP - 1065 PG - 15 SN - 0016-6731 DO - 10.1534/genetics.109.112060 UR - https://m2.mtmt.hu/api/publication/1921070 ID - 1921070 N1 - Megjegyzés-22194237 DI: 10.1534/genetics.109.112060 LA - English DB - MTMT ER - TY - JOUR AU - Weber, U AU - Pataki, Andrea Csilla AU - Mihály, József AU - Mlodzik, M TI - Combinatorial signaling by the Frizzled/PCP and Egfr pathways during planar cell polarity establishment in the Drosophila eye JF - DEVELOPMENTAL BIOLOGY J2 - DEV BIOL VL - 316 PY - 2008 IS - 1 SP - 110 EP - 123 PG - 14 SN - 0012-1606 DO - 10.1016/j.ydbio.2008.01.016 UR - https://m2.mtmt.hu/api/publication/1916859 ID - 1916859 AB - Frizzled (Fz)/PCP signaling regulates planar, vectorial orientation of cells or groups of cells within whole tissues. Although Fz/PCP signaling has been analyzed in several contexts, little is known about nuclear events acting downstream of Fz/PCP signaling in the R3/R4 cell fate decision in the Drosophila eye or in other contexts. Here we demonstrate a specific requirement for Egfir-signaling and the transcription factors Fos (AP-1), Yan and Put in PCP dependent R3/R4 specification. Loss and gain-of-function assays suggest that the transcription factors integrate input from Fz/ PCP and Egfr-signaling and that the ETS factors Pnt and Yan cooperate with Fos (and Jun) in the PCP-specific R3/R4 determination. Our data indicate that Fos (either downstream of Fz/PCP signaling or parallel to it) and Yan are required in R3 to specify its fate (Fos) or inhibit R4 fate (Yan) and that Egfr-signaling is required in R4 via Pnt for its fate specification. Taken together with previous work establishing a Notch-dependent Su(H) function in R4. we conclude that Fos, Yan, Put, and Su(H) integrate Egfr, Fz, and Notch signaling input in R3 or R4 to establish cell fate and ommatidial polarity. (C) 2008 Elsevier Inc. All rights reserved. LA - English DB - MTMT ER - TY - JOUR AU - Matusek, Tamás AU - Gombos, Rita I AU - Szécsényi, Anita AU - Sanchez-Soriano, N AU - Czibula, Ágnes AU - Pataki, Andrea Csilla AU - Gedai, Anita AU - Prokop, A AU - Raskó, István AU - Mihály, József TI - Formin Proteins of the DAAM Subfamily Play a Role during Axon Growth JF - JOURNAL OF NEUROSCIENCE J2 - J NEUROSCI VL - 28 PY - 2008 IS - 49 SP - 13310 EP - 13319 PG - 10 SN - 0270-6474 DO - 10.1523/JNEUROSCI.2727-08.2008 UR - https://m2.mtmt.hu/api/publication/1343161 ID - 1343161 N1 - Megjegyzés-22113753 DI: 10.1523/JNEUROSCI.2727-08.2008 Megjegyzés-22202239 DI: 10.1523/JNEUROSCI.2727-08.2008 AB - The regulation of growth cone actin dynamics is a critical aspect of axonal growth control. Among the proteins that are directly involved in the regulation of actin dynamics, actin nucleation factors play a pivotal role by promoting the formation of novel actin filaments. However, the essential nucleation factors in developing neurons have so far not been clearly identified. Here, we show expression data, and use true loss-of-function analysis and targeted expression of activated constructs to demonstrate that the Drosophila formin DAAM plays a critical role in axonal morphogenesis. In agreement with this finding, we show that dDAAM is required for filopodia formation at axonal growth cones. Our genetic interaction, immunoprecipitation and protein localization studies argue that dDAAM acts in concert with Rac GTPases, Profilin and Enabled during axonal growth regulation. We also show that mouse Daam1 rescues the CNS defects observed in dDAAM mutant flies to a high degree, and vice versa, that Drosophila DAAM induces the formation of neurite-like protrusions when expressed in mouse P19 cells, strongly suggesting that the function of DAAM in developing neurons has been conserved during evolution. LA - English DB - MTMT ER - TY - JOUR AU - Rus, Florentina AU - Kurucz, Judit Éva AU - Márkus, Róbert AU - Sinenko, SA AU - Laurinyecz, Barbara AU - Pataki, Andrea Csilla AU - Gausz, János AU - Hegedűs, Zoltán AU - Udvardy, Andor AU - Hultmark, D AU - Andó, István TI - Expression pattern of Filamin-240 in Drosophila blood cells JF - GENE EXPRESSION PATTERNS J2 - GENE EXPR PATTERNS VL - 6 PY - 2006 IS - 8 SP - 928 EP - 934 PG - 7 SN - 1567-133X DO - 10.1016/j.modgep.2006.03.005 UR - https://m2.mtmt.hu/api/publication/1786592 ID - 1786592 N1 - Export Date: 27 January 2024; CODEN: GEPEA LA - English DB - MTMT ER - TY - JOUR AU - Mihály, József AU - Matusek, Tamás AU - Pataki, Andrea Csilla TI - Diego and friends play again - Old planar cell polarity players in new positions JF - FEBS JOURNAL J2 - FEBS J VL - 272 PY - 2005 SP - 3241 EP - 3252 PG - 12 SN - 1742-464X DO - 10.1111/j.1742-4658.2005.04758.x UR - https://m2.mtmt.hu/api/publication/1913929 ID - 1913929 LA - English DB - MTMT ER -