TY  - JOUR
AU  - Bozzai, Barbara
AU  - Hasselblatt, M
AU  - Turányi, Eszter
AU  - Fruhwald, MC
AU  - Siebert, R
AU  - Bens, S
AU  - Schneppenheim, R
AU  - Kool, M
AU  - Stelczer, Gábor
AU  - Hortobágyi, Tibor
AU  - Hauser, Péter
TI  - Atypical teratoid/rhabdoid tumor arising in a malignant glioma
JF  - PEDIATRIC BLOOD & CANCER
J2  - PEDIATR BLOOD CANCER
VL  - 64
PY  - 2017
IS  - 1
SP  - 96
EP  - 99
PG  - 4
SN  - 1545-5009
DO  - 10.1002/pbc.26173
UR  - https://m2.mtmt.hu/api/publication/3104826
ID  - 3104826
N1  - Peter Hauser and Tibor Hortobágyi are joint last/senior authors.
AB  - Atypical teratoid/rhabdoid tumor (AT/RT), a highly malignant brain tumor in young children, usually arises de novo and has only rarely been described as a secondary malignancy. Here, we present a case of a child with glioblastoma, who was treated postoperatively by a combination of temozolomide, irradiation, and bevacizumab. AT/RT was diagnosed as a secondary tumor, 2.5 years following primary diagnosis. The child died 13 months after the diagnosis of AT/RT. This case demonstrates that malignant gliomas may give rise to AT/RT. It also emphasizes the diagnostic value of a repeated tumor biopsy in the recurrence setting.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Pócza, Tímea
AU  - Krenács, Tibor
AU  - Turányi, Eszter
AU  - Csáthy, J
AU  - Jakab, Zsuzsanna
AU  - Hauser, Péter
TI  - High expression of DNA methyltransferases in primary human medulloblastoma
JF  - FOLIA NEUROPATHOLOGICA
J2  - FOLIA NEUROPATHOL
VL  - 54
PY  - 2016
IS  - 2
SP  - 105
EP  - 113
PG  - 9
SN  - 1641-4640
DO  - 10.5114/fn.2016.60365
UR  - https://m2.mtmt.hu/api/publication/3094750
ID  - 3094750
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Bihari, J
AU  - Hornyák, Csilla
AU  - Szőke, Kristóf
AU  - Vajda, János
AU  - Bagó, Attila György
AU  - Varallyay, G
AU  - Turányi, Eszter
AU  - Rozsa, I
AU  - Debreczeni, Róbert
AU  - Bereczki, Dániel
AU  - Kovács, Tibor
TI  - Corticobasal Syndrome Due to Superficial Siderosis Caused by Thalamic Cavernoma
JF  - JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES
J2  - J NEUROPSYCH CLIN N
VL  - 28
PY  - 2016
IS  - 1
SP  - e15
EP  - e16
PG  - 2
SN  - 0895-0172
DO  - 10.1176/appi.neuropsych.15080196
UR  - https://m2.mtmt.hu/api/publication/3023608
ID  - 3023608
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Mózes, Petra
AU  - Hauser, Péter
AU  - Hortobágyi, Tibor
AU  - Benyó, Gábor
AU  - Peták, István
AU  - Garami, Miklós
AU  - Cserháti, Adrienn
AU  - Bartyik, Katalin
AU  - Bognár, László
AU  - Nagy, Zoltán
AU  - Turányi, Eszter
AU  - Hideghéty, Katalin
TI  - Evaluation of the good tumor response of embryonal tumor with abundant neuropil and true rosettes (ETANTR).
JF  - JOURNAL OF NEURO-ONCOLOGY
J2  - J NEURO-ONCOL
VL  - 126
PY  - 2016
IS  - 1
SP  - 99
EP  - 105
PG  - 7
SN  - 0167-594X
DO  - 10.1007/s11060-015-1938-3
UR  - https://m2.mtmt.hu/api/publication/2946462
ID  - 2946462
N1  - Funding Agency and Grant Number: EU-CELLEUROPE [EU315963]
            Funding text: This work was supported by EU-CELLEUROPE (EU315963) project.
AB  - The embryonal tumor with abundant neuropil and true rosettes is a rare and highly malignant variant of embryonal brain tumors. It usually affects infants and young children under the age of 4 years and exhibits a very aggressive course with a dismal prognosis. For the 68 cases reported to date the mean age at diagnosis was 25.42 months (range 3-57 months). Survival data are available for 48 children (including our case): the median overall survival is 13.0 months, though 6 (9 %) of the children have had a relative long survival (>30 months). The aggressive combined treatment, involving primary surgical tumor removal, adjuvant polychemotherapy, including high-dose chemotherapy with stem cell transplantation, radiotherapy and radiochemotherapy, might play an important role in the longer survival. We have performed a literature review and we present here a multimodal-treated case of a 2- year-old girl with a long survival, who was reoperated when recurrence occurred. The residual tumor demonstrated a good response to temozolomide radiochemotherapy (craniospinal axis + boost) and followed by maintenance temozolomide. The described complex aggressive treatment option might be considered for future cases of this tumor entity.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Szikora, István
AU  - Turányi, Eszter
AU  - Marosfői, Miklós
TI  - Evolution of Flow-Diverter Endothelialization and Thrombus Organization in Giant Fusiform Aneurysms after Flow Diversion: A Histopathologic Study.
JF  - AMERICAN JOURNAL OF NEURORADIOLOGY
J2  - AM J NEURORADIOL
VL  - 36
PY  - 2015
IS  - 9
SP  - 1716
EP  - 1720
PG  - 5
SN  - 0195-6108
DO  - 10.3174/ajnr.A4336
UR  - https://m2.mtmt.hu/api/publication/2937994
ID  - 2937994
AB  - BACKGROUND AND PURPOSE: Treatment of giant fusiform aneurysms with flow diverters has been associated with a relatively high rate of complications. Our goal was to study the evolution of flow-diverter endothelialization and thrombus organization at different time points after flow-diverter treatment in giant fusiform aneurysms to better understand reasons for flow-diverter thrombosis and delayed aneurysm ruptures. MATERIALS AND METHODS: Two giant anterior and 2 posterior circulation aneurysms, all of which had partially thrombosed before treatment, were studied. An unruptured, untreated posterior circulation aneurysm was used as a control. Each specimen was removed at 7 days or at 6, 9, or 13 months after flow-diverter treatment. The 3 patients who survived longer than 7 days were followed up by angiography and MR imaging. Formaldehyde-fixed paraffin-embedded sections were stained by using H&E, Van Gieson elastic, CD34, h-Caldesmon, and Picrosirius stains and studied by light microscopy. RESULTS: According to angiography, aneurysms were found to be obliterated partially at 6 and 9 months and completely at 13 months. MR imaging revealed that mass effect remained unchanged in each case. Sections of the flow diverter within the normal parent artery were covered by an endothelialized fibrous layer as early as 6 months, but there was no tissue coverage or endothelialization seen even at 13 months inside the aneurysm itself. Each treated aneurysm had a thin wall with complete lack of smooth muscle cells. No signs of thrombus organization were found at any of the time points studied. CONCLUSIONS: Endothelialization of the flow diverter in giant fusiform aneurysms may not occur and thrombus organization may not be initiated inside these aneurysms for as long as 1 year, which explains delayed flow-diverter thrombosis and the possibility of delayed ruptures.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Pump, Ágnes
AU  - Robert, B
AU  - Turányi, Eszter
TI  - Search for comorbidities before the surgery of aortic stenosis.
JF  - EUROPEAN HEART JOURNAL
J2  - EUR HEART J
VL  - 36
PY  - 2015
IS  - 36
SP  - 2471
EP  - 2471
PG  - 1
SN  - 0195-668X
DO  - 10.1093/eurheartj/ehu399
UR  - https://m2.mtmt.hu/api/publication/2932578
ID  - 2932578
N1  - CARDIOVASCULAR FLASHLIGHT

Ajánlás az MTMT számára a tudományos folyóiratokban sajátos megjelenésű rovatokban megjelenő közlemények... (2012.12.21.) 2.3 pontja alapján átsorolva Ismertetéssé.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Reiniger, Lilla
AU  - Hanzély, Z
AU  - Bálint, Katalin
AU  - Turányi, Eszter
TI  - Az agydaganatok molekuláris diagnosztikája
JF  - KLINIKAI ONKOLÓGIA
J2  - KLINIKAI ONKOLÓGIA
VL  - 2
PY  - 2015
IS  - 1
SP  - 51
EP  - 55
PG  - 6
SN  - 2064-5058
UR  - https://m2.mtmt.hu/api/publication/2859803
ID  - 2859803
LA  - Hungarian
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Tőkés, Anna-Mária
AU  - Szász, Attila Marcell
AU  - Geszti, F
AU  - Lukacs, LV
AU  - Kenessey, István
AU  - Turányi, Eszter
AU  - Meggyesházi, Nóra
AU  - Molnár, István Artúr
AU  - Fillinger, János
AU  - Soltesz, I
AU  - Bálint, Katalin
AU  - Hanzely, Z
AU  - Arató, Gabriella
AU  - Szendrői, Miklós
AU  - Kulka, Janina
TI  - Expression of proliferation markers Ki67, cyclin A, geminin and aurora-kinase A in primary breast carcinomas and corresponding distant metastases.
JF  - JOURNAL OF CLINICAL PATHOLOGY
J2  - J CLIN PATHOL
VL  - 68
PY  - 2015
IS  - 4
SP  - 274
EP  - 282
PG  - 9
SN  - 0021-9746
DO  - 10.1136/jclinpath-2014-202607
UR  - https://m2.mtmt.hu/api/publication/2821045
ID  - 2821045
N1  - Tőkés Anna-Mária & Szász Attila Marcell are equal first authors
AB  - AIMS: To assess the expression of the following cell cycle regulatory proteins in primary metastatic breast carcinomas (MBCs) and on availability in matched distant metastases (DMs): Ki67, cyclin A, geminin and aurora-kinase A (aurkA); and to compare the expression of these markers in early MBC (EMBC) and late MBC separated into groups according to median time point on metastatic event occurred (28 months). METHODS: The expression of the above mentioned markers was analysed in a total of 47 primary MBCs and 59 DMs (out of which 37 were pairs) by immunohistochemistry. Fourteen breast carcinomas with no relapse over a 10-year follow-up period were utilised as control cases (CBC). RESULTS: Among the MBCs, 22 metastasised to the bone, 4 to the lung and 21 to the central nervous system (CNS). Geminin (p<0.001) and Ki67 (p=0.001) were increased in the MBCs while aurkA and cyclin A showed no difference when compared with CBCs. There were no differences between aurkA, cyclin A and geminin expression in MBCs and DMs in general. Expression of Ki67 was, however, elevated (p=0.027) in DMs. In CNS metastases all markers showed elevated expression as compared to MBCs. In bone metastases, geminin was lower (p<0.001) compared with primary MBCs. In the metastases of the lung, the evaluated markers did not show different expression. According to the median follow-up until the metastatic event, Ki67 was found to be significantly elevated in EMBC (p=0.018). CONCLUSIONS: Ki67 index and geminin distinguish a fraction of MBC with worse prognosis, showing increased levels in the latter in comparison to CBC being tumour-free over a 10-year follow-up period. Ki67 could possibly identify a group of MBCs that develop early DMs.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Vitanovics, Dusan
AU  - Áfra, Dénes
AU  - Nagy, Gábor
AU  - Hanzely, Z
AU  - Turányi, Eszter
AU  - Banczerowski, Péter
TI  - SYMPTOMATIC SUBEPENDYMOMAS OF THE VENTRICLES. REVIEW OF TWENTY CONSECUTIVE CASES
JF  - IDEGGYOGYASZATI SZEMLE / CLINICAL NEUROSCIENCE
J2  - IDEGGYOGY SZEMLE
VL  - 67
PY  - 2014
IS  - 11-12
SP  - 415
EP  - 419
PG  - 5
SN  - 0019-1442
UR  - https://m2.mtmt.hu/api/publication/2836367
ID  - 2836367
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Tokes, A
AU  - Szász, Attila Marcell
AU  - Kenessey, István
AU  - Lukacs, L V
AU  - Turányi, Eszter
AU  - Meggyesházi, Nóra
AU  - Harsanyi, L
AU  - Arató, Gabriella
AU  - Szendrői, Miklós
AU  - Kulka, J
TI  - Expression of proliferation markers Aurora kinase A, geminin, Cyclin A and Ki67 in primary breast carcinomas and corresponding distant metastases
JF  - EUROPEAN JOURNAL OF CANCER
J2  - EUR J CANCER
VL  - 50
PY  - 2014
IS  - 2
SP  - S193
EP  - S193
SN  - 0959-8049
UR  - https://m2.mtmt.hu/api/publication/2748825
ID  - 2748825
LA  - English
DB  - MTMT
ER  -