@article{MTMT:34729907,
	title = {Short-term outcomes of treatment switch to faricimab in patients with aflibercept-resistant neovascular age-related macular degeneration},
	url = {https://m2.mtmt.hu/api/publication/34729907},
	author = {Schneider, Miklós and Bjerager, J. and Hodzic-Hadzibegovic, D. and Klefter, O.N. and Subhi, Y. and Hajari, J.},
	doi = {10.1007/s00417-024-06421-0},
	journal-iso = {GRAEF ARCH CLIN EXP},
	journal = {GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY},
	unique-id = {34729907},
	issn = {0721-832X},
	year = {2024},
	eissn = {1435-702X},
	orcid-numbers = {Schneider, Miklós/0000-0003-1488-4743}
}

@article{MTMT:34631721,
	title = {Endophthalmitis following same-day bilateral anti-VEGF injections. a systematic review.},
	url = {https://m2.mtmt.hu/api/publication/34631721},
	author = {Bjerager, Jakob and Hajari, Javad and Klefter, Oliver Niels and Subhi, Yousif and Schneider, Miklós},
	doi = {10.1007/s10792-024-02983-4},
	journal-iso = {INT OPHTHALMOL},
	journal = {INTERNATIONAL OPHTHALMOLOGY},
	volume = {44},
	unique-id = {34631721},
	issn = {0165-5701},
	abstract = {To review the risk of endophthalmitis in same-day bilateral anti-VEGF injections.We searched 12 literature databases for studies on the risk of endophthalmitis after same-day bilateral intravitreal anti-VEGF injections. Data extraction was made independently by two authors and discussed afterward until reaching consensus.Seventeen studies were included with a total of 138,478 intravitreal anti-VEGF injections (69,239 bilateral injections sessions) given in at least 7579 patients. In total, 33 cases of endophthalmitis had occurred, and no cases were bilateral. The incidence of endophthalmitis ranged from 0 to 0.53% per intravitreal injection across studies.We suggest that clinicians can consider same-day treatment of both eyes of patients in need of bilateral intravitreal anti-VEGF injection therapy, but larger studies are needed to quantify the exact risk of endophthalmitis.},
	keywords = {RISK; injection; systematic review; Bilateral; ENDOPHTHALMITIS; intravitreal; adverse event; Anti-VEGF; SAME-DAY; Same-session},
	year = {2024},
	eissn = {1573-2630},
	orcid-numbers = {Schneider, Miklós/0000-0003-1488-4743}
}

@article{MTMT:34571247,
	title = {Effect of Needle Gauge Size on Pain During Intravitreal Anti-VEGF Injection: A Systematic Review and Network Meta-Analysis},
	url = {https://m2.mtmt.hu/api/publication/34571247},
	author = {Butler, Emilie T. S. and Bjerager, Jakob and Eriksen, Nathalie S. and Hajari, Javad N. and Schneider, Miklós and Faber, Carsten and Subhi, Yousif},
	doi = {10.1007/s40123-023-00879-7},
	journal-iso = {OPHTHALMOL THERAP},
	journal = {OPHTHALMOLOGY AND THERAPY},
	volume = {13},
	unique-id = {34571247},
	issn = {2193-8245},
	abstract = {IntroductionConcerns related to pain from intravitreal injections are one of the key factors mentioned by patients when asked about therapy. In this systematic review and network meta-analysis, we evaluate the literature of comparative clinical trials on the relationship between needle gauge size and pain experience during intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy.MethodsWe searched 12 literature databases on 14 October 2023 for comparative studies of gauge sizes for intravitreal anti-VEGF injections. The primary outcome of interest was the reported pain experience immediately after the injection. All outcomes of pain were transformed into standardized effect sizes using Cohen's d. Using a network meta-analysis approach, we were able to compare all gauge sizes and rank them according to the reported pain experience.ResultsWe identified nine eligible studies with data on a total of 998 patients and 1004 eyes. Needle sizes studied were 26-gauge, 27-gauge, 29-gauge, 30-gauge, 32-gauge, 33-gauge, and 34-gauge. A complete network was present, which allowed for a network meta-analysis. We used the thickest (26-gauge) needle as the reference group and observed a clear trend of lower pain experience with thinner gauge sizes (d: -0.4, d: -2.7, d: -3.8, d: -4.8, d: -4.5, and d: -5.3; respectively, for 27-gauge, 29-gauge, 30-gauge, 32-gauge, 33-gauge, and 34-gauge).ConclusionA gauge size of 30 or thinner may minimize patient discomfort related to intravitreal anti-VEGF therapy.},
	keywords = {PAIN; DEPRESSION; EXPERIENCE; systematic review; MACULAR DEGENERATION; Intravitreal injection; patient comfort; Anti-VEGF},
	year = {2024},
	eissn = {2193-6258},
	pages = {801-817},
	orcid-numbers = {Schneider, Miklós/0000-0003-1488-4743; Subhi, Yousif/0000-0001-6620-5365}
}

@article{MTMT:34517346,
	title = {Systemic adverse events and all-cause mortality following same-session bilateral intravitreal anti-VEGF injections: a systematic review},
	url = {https://m2.mtmt.hu/api/publication/34517346},
	author = {Bjerager, Jakob and Hajari, Javad and Klefter, Oliver Niels and Subhi, Yousif and Schneider, Miklós},
	doi = {10.1007/s00417-023-06368-8},
	journal-iso = {GRAEF ARCH CLIN EXP},
	journal = {GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY},
	unique-id = {34517346},
	issn = {0721-832X},
	abstract = {PurposeTo review the risk of systemic adverse events and all-cause mortality following same-day bilateral anti-VEGF injections.MethodsTwelve literature databases were searched for studies on same-session bilateral intravitreal anti-VEGF injections. Studies reporting on systemic adverse events and mortality were included. Data extraction was made independently by two authors and discussed afterwards until consensus was reached.ResultsSeven studies were included with a total of 13,406 intravitreal anti-VEGF injections (6703 bilateral injections sessions) given to 689 patients. Across all studies, mean age of patients ranged from 55.7 to 82.5 years, and mean follow-up times ranged from 1.3 to 41 months. Six studies reported on systemic adverse events: Two cases of non-fatal cardiac adverse events were reported after 12,964 injections (6482 bilateral injection sessions) in 626 patients. Four studies reported on death: 12 deaths were recorded after 6233 bilateral injection sessions in a total population of 554 subjects.ConclusionsWe suggest that the risk of non-fatal systemic adverse events and death after same-session bilateral anti-VEGF injection is reasonably low, but larger studies with follow-ups of several years are needed to quantify the exact risk.Study registration.Prospectively registered in PROSPERO, registration ID: CRD42023428254, registration date: 20/05/2023.},
	keywords = {RISK; DEATH; MORTALITY; injection; ENDOTHELIAL GROWTH-FACTOR; MACULAR DEGENERATION; Bilateral; intravitreal; adverse event; Anti-VEGF; SAME-DAY; Same-session},
	year = {2024},
	eissn = {1435-702X},
	orcid-numbers = {Klefter, Oliver Niels/0000-0003-2313-5648; Schneider, Miklós/0000-0003-1488-4743}
}

@article{MTMT:34505335,
	title = {Long-term follow-up of a bilateral acute posterior multifocal placoid pigment epitheliopathy following COVID-19 infection: a case report},
	url = {https://m2.mtmt.hu/api/publication/34505335},
	author = {Lund-Andersen, C. and Klefter, O.N. and Schneider, Miklós},
	doi = {10.1186/s12348-023-00382-x},
	journal-iso = {JOURNAL OF OPHTHALMIC INFLAMMATION AND INFECTION},
	journal = {JOURNAL OF OPHTHALMIC INFLAMMATION AND INFECTION},
	volume = {14},
	unique-id = {34505335},
	issn = {1869-5760},
	year = {2024},
	orcid-numbers = {Schneider, Miklós/0000-0003-1488-4743}
}

@article{MTMT:34231337,
	title = {Exudative Progression of Treatment-Naïve Nonexudative Macular Neovascularization in Age-Related Macular Degeneration: A Systematic Review With Meta-Analyses},
	url = {https://m2.mtmt.hu/api/publication/34231337},
	author = {Nissen, A.H.K. and Kiilgaard, H.C. and van, Dijk E.H.C. and Hajari, J.N. and Huemer, J. and Iovino, C. and Schneider, Miklós and Sørensen, T.L. and Grauslund, J. and Subhi, Y.},
	doi = {10.1016/j.ajo.2023.08.020},
	journal-iso = {AM J OPHTHALMOL},
	journal = {AMERICAN JOURNAL OF OPHTHALMOLOGY},
	volume = {257},
	unique-id = {34231337},
	issn = {0002-9394},
	year = {2024},
	eissn = {1879-1891},
	pages = {46-56},
	orcid-numbers = {Schneider, Miklós/0000-0003-1488-4743}
}

@article{MTMT:34106052,
	title = {Topical non-steroidal anti-inflammatory drugs for central serous chorioretinopathy: A systematic review and meta-analysis},
	url = {https://m2.mtmt.hu/api/publication/34106052},
	author = {Larsson, J.M.E. and Boberg-Ans, L.C. and Vangsted, A. and van, Dijk E.H.C. and Grauslund, J. and Hajari, J.N. and Klefter, O.N. and Schneider, Miklós and Subhi, Y.},
	doi = {10.1111/aos.15743},
	journal-iso = {ACTA OPHTHALMOL},
	journal = {ACTA OPHTHALMOLOGICA},
	volume = {102},
	unique-id = {34106052},
	issn = {1755-375X},
	abstract = {Central serous chorioretinopathy (CSC) is a prevalent exudative maculopathy and the ongoing verteporfin shortage restricts current treatment possibilities. Topical non-steroidal anti-inflammatory drugs (NSAID) have previously been proposed as a treatment for CSC, although its exact efficacy remains unclear. In this systematic review and meta-analysis, we outlined the efficacy of topical NSAIDs for the treatment of CSC. We searched 11 literature databases on 13 December 2022, for any study describing topical NSAID treatment for CSC. Thirteen eligible studies were included with a total of 1001 eyes of 994 patients with CSC. Six studies were case reports, two were cohort studies and five were non-randomized comparative studies. Where specified, topical NSAIDs used were bromfenac 0.09%, diclofenac 0.1%, ketorolac 0.4% and 0.5%, pranoprofen 0.1%, and nepafenac 0.1% and 0.3%. Studies were predominantly of cases with acute CSC and several case studies reported treatment outcomes simultaneously with discontinuation of corticosteroid use, which complicated treatment evaluation. Meta-analyses of comparative studies revealed a statistically significant but clinically irrelevant best-corrected visual acuity improvement of −0.04 logMAR (95% CI: −0.07 to −0.01 logMAR; p = 0.01) at 1-month follow-up, which became statistically insignificant at 3-month follow-up (−0.03 logMAR; 95% CI: −0.06 to 0.003 logMAR; p = 0.08). Further, we found no benefit in complete subretinal fluid resolution at 1-month follow-up (OR: 1.20; 95% CI: 0.81–1.76; p = 0.37) or 3-month follow-up (OR: 1.17; 95% CI: 0.86 to 1.59; p = 0.33). Taken together, available evidence does not support the use of topical NSAIDs for the treatment of CSC. © 2023 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.},
	keywords = {non-steroidal anti-inflammatory drugs; Meta-analysis; systematic review; subretinal fluid; Central serous chorioretinopathy},
	year = {2024},
	eissn = {1755-3768},
	pages = {274-284},
	orcid-numbers = {Schneider, Miklós/0000-0003-1488-4743}
}

@article{MTMT:34392020,
	title = {Felnőttkori B-típusú Niemann–Pick-betegség szemészeti manifesztációja},
	url = {https://m2.mtmt.hu/api/publication/34392020},
	author = {Angeli, Orsolya and Nagy, Zoltán Zsolt and Schneider, Miklós},
	doi = {10.1556/650.2023.32927},
	journal-iso = {ORV HETIL},
	journal = {ORVOSI HETILAP},
	volume = {164},
	unique-id = {34392020},
	issn = {0030-6002},
	abstract = {A Niemann–Pick-betegség a lizoszomális tárolási betegségek csoportjába tartozó ritka, autoszomális recesszíven öröklődő betegség. Hátterében a szfingomielináz enzim hiánya vagy csökkent működése, illetve az intracelluláris koleszterintranszporter fehérje deficientiája áll, és a lebontási zavar miatt a sejtek lizoszómáiban szfingomielin és koleszterin szaporodik fel. A betegség 5 altípusát (A, A/B, B, C, D) különböztetjük meg. A szerzők egy 24 éves, gyermekkorában B-típusú Niemann–Pick-betegséggel diagnosztizált fiatal férfi esetét mutatják be, különös tekintettel a betegség szemészeti manifesztációjára. A beteg vizsgálata során fundusfotók és fundusautofluoreszcencia-felvételek készültek, továbbá optikaikoherencia-tomográfiás (OCT-), OCT-angiográfiás (OCTA-) és látótér (perimetria)-vizsgálatok történtek. A szemfenék vizsgálatakor, illetve a fundusfotókon jól látszott a betegségre jellegzetes macularis gyűrű alakú udvar (továbbiakban halo) és a cseresznyepiros folt a foveában. Az OCT-felvételeken a macularis halo megfelelően nagy reflektivitású, fokális megvastagodás ábrázolódott a ganglionsejtrétegben, a foveola területe megkímélt volt. A látótérvizsgálattal mindkét szem látótere ép volt. A bemutatott páciens esetéhez hasonlóan a B-altípusba tartozó betegeknél a tünetek enyhébbek, a visceralis tünetek mellett idegrendszeri tünetek nincsenek, és a specifikus szemészeti eltérések nem okoznak látásromlást. Jelenleg a Niemann–Pick-betegség ritka betegségnek számít, sok esetben a betegek diagnózisa késik vagy akár el is maradhat az aspecifikus vagy enyhe tünetek miatt. A szakterületek közötti konzultáció révén belgyógyászati szempontból tünetszegény esetekben a szemészeti vizsgálat is hozzájárulhat a jó diagnózishoz. Az időben történő diagnózissal a tünetek az egyre bővülő terápiás lehetőségeknek köszönhetően mérsékelhetők, a betegség progressziója stabilizálható, a betegek élettartama így növekedhet. Orv Hetil. 2023; 164(46): 1838–1844.},
	year = {2023},
	eissn = {1788-6120},
	pages = {1838-1844},
	orcid-numbers = {Nagy, Zoltán Zsolt/0000-0002-7330-0464; Schneider, Miklós/0000-0003-1488-4743}
}

@article{MTMT:34237412,
	title = {Anterior segment optical coherence tomography-assisted surgical planning of an organic intralamellar corneal foreign body removal: a case report},
	url = {https://m2.mtmt.hu/api/publication/34237412},
	author = {Volek, Eva and Sándor, Gábor László and Nagy, Zoltán Zsolt and Schneider, Miklós},
	doi = {10.1007/s00717-023-00551-2},
	journal-iso = {SPEKTRUM AUGENHEILKD},
	journal = {SPEKTRUM DER AUGENHEILKUNDE},
	unique-id = {34237412},
	issn = {0930-4282},
	abstract = {BackgroundCorneal foreign bodies have been reported to be the second most common type of ocular injury. We report a case of an organic intralamellar foreign body in which noninvasive anterior segment optical coherence tomography (AS-OCT) was used to assist the diagnosis, plan the surgery, and monitor the progress of treatment.Case presentationA 37-year-old male patient presented with an intracorneal reed foreign body in his right eye. It was challenging to assess whether the foreign body perforated the cornea. Slit-lamp examination and AS-OCT were performed. The latter showed that the foreign body had not completely perforated the cornea. Removal of the foreign body via the entry wound was not possible due to the structure of the reed. Extraction was performed via an incision along the foreign body. During the postoperative period, the patient's visual acuity was 20/20 on the right eye with minimal astigmatism, despite a scar tissue formation.ConclusionsIn our case, AS-OCT facilitated the localization of the corneal foreign body and was useful in planning the surgery. HintergrundEs ist bekannt, dass Verletzungen mit Hornhautfremdkorper die zweithaufigste Art von Augenverletzungen sind. Es wird uber den Fall eines organischen intralamellaren Fremdkorpers berichtet, bei dem eine nichtinvasive optische Koharenztomographie des vorderen Augenabschnitts (AS-OCT) zur Feststellung der Diagnose, Planung der Operation und uberwachung des Behandlungsfortschritts durchgefuhrt wurde.FalldarstellungEin 37-jahriger Patient mit einem intrakornealen Schilfrohr-Fremdkorper im rechten Auge wurde untersucht. Es war schwierig zu beurteilen, ob der Fremdkorper die Hornhaut perforierte oder nicht. Spaltlampenuntersuchung und AS-OCT wurden durchgefuhrt. Letztere zeigte, dass der Fremdkorper die Hornhaut nicht vollstandig perforiert hatte. Die Entfernung des Fremdkorpers uber die Eintrittswunde war aber aufgrund der Schilfstruktur nicht moglich. Die Extraktion erfolgte uber einen Schnitt entlang des Fremdkorpers. Wahrend der postoperativen Phase betrug die Sehscharfe des Patienten trotz Narbenbildung 20/20 auf dem rechten Auge bei minimalem Astigmatismus.SchlussfolgerungIm vorliegenden Fall erleichterte die AS-OCT die Lokalisierung des Hornhautfremdkorpers und war hilfreich bei der Planung der Operation.},
	keywords = {INJURY; REED; foreign body; Imaging; Eye; Cornea; anterior segment; Spectral-domain optical coherence tomography; ocular trauma; Hornhaut; Non-perforating; Intralamellar; Augentrauma; Nicht perforierend; Verletzung; Bildgebung; Schilfrohr; Fremdkorper; Vorderer Augenabschnitt},
	year = {2023},
	eissn = {1613-7523},
	orcid-numbers = {Sándor, Gábor László/0000-0002-2484-9848; Nagy, Zoltán Zsolt/0000-0002-7330-0464; Schneider, Miklós/0000-0003-1488-4743}
}

@article{MTMT:34190266,
	title = {Qualitative and quantitative comparison of two semi-manual retinal vascular density analyzing methods on optical coherence tomography angiography images of healthy individuals},
	url = {https://m2.mtmt.hu/api/publication/34190266},
	author = {Angeli, Orsolya and Hajdu, Dorottya and Jeney, Aniko and Czifra, Balint and Nagy, Balázs Vince and Balazs, Tamas and Jakaboczkine Nemoda, Dora and Somfai, Gábor Márk and Nagy, Zoltán Zsolt and Peto, Tunde and Schneider, Miklós},
	doi = {10.1038/s41598-023-44234-z},
	journal-iso = {SCI REP},
	journal = {SCIENTIFIC REPORTS},
	volume = {13},
	unique-id = {34190266},
	issn = {2045-2322},
	abstract = {The aim of this study was to evaluate qualitative and quantitative differences in vascular density analysis of an established and a novel alternative for post-processing on optical coherence tomography angiography (OCTA) images in healthy individuals. OCTA examinations of 38 subjects were performed. After extracting the images, two semi-manual post-processing techniques, the already established Mexican hat filtering (MHF) and an alternative, the Shanbhag thresholding (ST) were applied. We assessed Vessel Density (VD), Skeleton Density (SkD) and Vessel Diameter Index (VDI). We analyzed the results in order to establish similarities or potentially relevant differences. Regarding SkD and VD, MHF generally gave higher values than ST. Simultaneously, mean values were also predominantly higher by MHF; however, standard deviations (SD) were higher by ST (range [mean ± SD]: 0.054 ± 0.038 to 0.134 ± 0.01 and 0.134 ± 0.095 to 0.362 ± 0.028 vs 0.012 ± 0.014 to 0.087 ± 0.03 and 0.039 ± 0.047 to 0.4 ± 0.095 for SkD and VD with MHF vs SkD and VD with ST, respectively). Values of VDI were considerably higher with ST than with MHF, while standard deviation was still significantly higher with ST (range [mean ± SD]: 2.459 ± 0.144 to 2.71 ± 0.084 and 2.983 ± 0.929 to 5.19 ± 1.064 for VDI with MHF and ST, respectively). The noise level reduction of the two methods were almost identical (noise levels: 65.8% with MHT and 65.24% with ST). Using MHF, the vascular network gets more fragmented by an average of 40% compared to ST. Both methods allow the segmentation of the vascular network and the examination of vascular density parameters, but they produce largely inconsistent results. To determine if these inconsistent results are clinically meaningful, and which method is more suitable for clinical use, our results provide further evidence that detailed understanding of the image analysis method is essential for reliable decision making for patients with retinal pathology. For longitudinal monitoring, use of the same image processing method is recommended.},
	year = {2023},
	eissn = {2045-2322},
	orcid-numbers = {Nagy, Balázs Vince/0000-0002-8489-7200; Somfai, Gábor Márk/0000-0001-6329-442X; Nagy, Zoltán Zsolt/0000-0002-7330-0464; Schneider, Miklós/0000-0003-1488-4743}
}