TY - JOUR AU - Major, Dávid AU - Fazekas-Pongor, Vince AU - Hung, Wei Yi AU - Sinhg-Manoux, Archana AU - Brunner, Eric J. AU - Kivimaki, Mika AU - Tabák, Ádám TI - Testösszetétel trajektóriák alakulása a cukorbetegség diagnózisát megelőző években JF - NÉPEGÉSZSÉGÜGY J2 - NÉPEGÉSZSÉGÜGY VL - 101 PY - 2024 IS - 2 SP - 135 EP - 135 PG - 1 SN - 0369-3805 UR - https://m2.mtmt.hu/api/publication/35180031 ID - 35180031 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Fazekas-Pongor, Vince AU - Domján, Beatrix Annamária AU - Major, Dávid AU - Péterfi, Anna AU - Horváth, Viktor József AU - Mészáros, Szilvia AU - Vokó, Zoltán AU - Vásárhelyi, Barna AU - Szabó, Attila AU - Burián, Katalin AU - Merkely, Béla Péter AU - Tabák, Ádám TI - Prevalence and determinants of diagnosed and undiagnosed diabetes in Hungary based on the nationally representative cross-sectional H-UNCOVER study JF - DIABETES RESEARCH AND CLINICAL PRACTICE J2 - DIABETES RES CLIN PR VL - 216 PY - 2024 PG - 9 SN - 0168-8227 DO - 10.1016/j.diabres.2024.111834 UR - https://m2.mtmt.hu/api/publication/35177632 ID - 35177632 LA - English DB - MTMT ER - TY - JOUR AU - Molnár, Adél AU - Juha, Márk AU - Bulajcsík, Klaudia AU - Tabák, Ádám AU - Tislér, András AU - Ledó, Nóra TI - Proposal of a novel cardiovascular risk prediction score in lupus nephritis JF - FRONTIERS IN IMMUNOLOGY J2 - FRONT IMMUNOL VL - 15 PY - 2024 PG - 12 SN - 1664-3224 DO - 10.3389/fimmu.2024.1405463 UR - https://m2.mtmt.hu/api/publication/35150116 ID - 35150116 LA - English DB - MTMT ER - TY - JOUR AU - Mészáros, Szilvia AU - Piroska, Márton AU - Leel-Őssy, Tamás AU - Tárnoki, Ádám Domonkos AU - Tárnoki, Dávid László AU - Jokkel, Zsófia AU - Szabó, Helga AU - Hosszú, Éva AU - Csupor, Emőke AU - Kollár, Réka AU - Kézdi, Árpád AU - Tabák, Ádám AU - Horváth, Csaba TI - Genetic and environmental determinants of bone quality: a cross-sectional analysis of the Hungarian Twin Registry JF - GEROSCIENCE: OFFICIAL JOURNAL OF THE AMERICAN AGING ASSOCIATION (AGE) J2 - GEROSCIENCE VL - In press PY - 2024 SP - In press SN - 2509-2715 DO - 10.1007/s11357-024-01265-2 UR - https://m2.mtmt.hu/api/publication/35082580 ID - 35082580 N1 - Department of Internal Medicine and Oncology, Faculty of Medicine, Semmelweis University, Budapest, Hungary Medical Imaging Centre, Faculty of Medicine, Semmelweis University, Budapest, Hungary Hungarian Twin Registry, Budapest, Hungary 2nd Department of Pediatrics, Faculty of Medicine, Semmelweis University, Budapest, Hungary Health Service, Buda Castle Local Authorities, Budapest, Hungary Department of Public Health, Faculty of Medicine, Semmelweis University, Budapest, Hungary Károly Rácz Conservative Medicine Division, Doctoral College, Semmelweis University, Budapest, Hungary UCL Brain Sciences, University College London, London, United Kingdom Export Date: 30 July 2024 Correspondence Address: Mészáros, S.; Department of Internal Medicine and Oncology, Hungary; email: meszaros.szilvia@semmelweis.hu AB - There is abundant evidence that bone mineral content is highly heritable, while the heritability of bone quality (i.e. trabecular bone score [TBS] and quantitative ultrasound index [QUI]) is rarely investigated. We aimed to disentangle the role of genetic, shared and unique environmental factors on TBS and QUI among Hungarian twins. Our study includes 82 twin (48 monozygotic, 33 same-sex dizygotic) pairs from the Hungarian Twin Registry. TBS was determined by DXA, QUI by calcaneal bone ultrasound. To estimate the genetic and environmental effects, we utilized ACE-variance decomposition. For the unadjusted model of TBS, an AE model provided the best fit with > 80% additive genetic heritability. Adjustment for age, sex, BMI and smoking status improved model fit with 48.0% of total variance explained by independent variables. Furthermore, there was a strong dominant genetic effect (73.7%). In contrast, unadjusted and adjusted models for QUI showed an AE structure. Adjustments improved model fit and 25.7% of the total variance was explained by independent variables. Altogether 70–90% of the variance in QUI was related to additive genetic influences. We found a strong genetic heritability of bone quality in unadjusted models. Half of the variance of TBS was explained by age, sex and BMI. Furthermore, the adjusted model suggested that the genetic component of TBS could be dominant or an epistasis could be present. In contrast, independent variables explained only a quarter of the variance of QUI and the additive heritability explained more than half of all the variance. LA - English DB - MTMT ER - TY - JOUR AU - Réti, Zsuzsanna AU - Tabák, Ádám AU - Garami, Miklós AU - Kalina, Ildikó AU - Kiss, Gergely AU - Sápi, Zoltán AU - Tóth, Miklós AU - Tőke, Judit TI - Spontaneous and Treatment-Related Changes of Serum Calcitonin in Medullary Thyroid Cancer: Long-Term Experience in a Patient With Multiple Endocrine Neoplasia Type 2B JF - JCO PRECISION ONCOLOGY J2 - JCO PRECIS ONCOL VL - 8 PY - 2024 PG - 7 SN - 2473-4284 DO - 10.1200/PO.23.00675 UR - https://m2.mtmt.hu/api/publication/34844873 ID - 34844873 N1 - Z.R. and A.G.T. contributed equally to this work. LA - English DB - MTMT ER - TY - JOUR AU - Pártos, Katalin AU - Major, Dávid AU - Dósa, Norbert Sándor AU - Fazekas-Pongor, Vince AU - Tabák, Ádám AU - Ungvári, Zoltán István AU - Horváth, Ildikó AU - Barta, Ildikó AU - Pozsgai, Éva AU - Bodnár, Tamás AU - Fehér, Gergely AU - Lenkey, Zsófia AU - Fekete, Mónika AU - Springó, Zsolt TI - Diagnosis rates, therapeutic characteristics, lifestyle, and cancer screening habits of patients with diabetes mellitus in a highly deprived region in Hungary: a cross-sectional analysis JF - FRONTIERS IN ENDOCRINOLOGY J2 - FRONT ENDOCRINOL VL - 15 PY - 2024 PG - 8 SN - 1664-2392 DO - 10.3389/fendo.2024.1299148 UR - https://m2.mtmt.hu/api/publication/34830215 ID - 34830215 N1 - * Megosztott szerzőség LA - English DB - MTMT ER - TY - JOUR AU - Gadó, Klára AU - Tabák, Ádám AU - Vingender, István AU - Domján, Gyula AU - Bednárikné Dörnyei, Gabriella TI - Treatment of type 2 diabetes mellitus in the elderly – Special considerations JF - PHYSIOLOGY INTERNATIONAL J2 - PHYSIOL INT VL - 111 PY - 2024 IS - 2 SP - 143 EP - 164 PG - 22 SN - 2498-602X DO - 10.1556/2060.2024.00317 UR - https://m2.mtmt.hu/api/publication/34826851 ID - 34826851 AB - Type 2 diabetes is a frequent chronic disease. Given its strong positive association with older age, it is a significant public health issue in elderly populations. Furthermore, the aging of the population, driven by increasing life expectancy in high and middle-income countries leads to an increasing prevalence of diabetes. LA - English DB - MTMT ER - TY - CHAP AU - Tabák, Ádám ED - Takács, István TI - Hypoglykaemiák T2 - Belgyógyászat 1 tantárgyi jegyzet PB - Semmelweis Kiadó CY - Budapest SN - 9789633316122 PY - 2024 SP - 145 EP - 147 PG - 3 UR - https://m2.mtmt.hu/api/publication/34804963 ID - 34804963 LA - Hungarian DB - MTMT ER - TY - CHAP AU - Tabák, Ádám ED - Takács, István TI - Ketoacidosis, hyperosmolaris coma T2 - Belgyógyászat 1 tantárgyi jegyzet PB - Semmelweis Kiadó CY - Budapest SN - 9789633316122 PY - 2024 SP - 142 EP - 145 PG - 4 UR - https://m2.mtmt.hu/api/publication/34804957 ID - 34804957 LA - Hungarian DB - MTMT ER - TY - CHAP AU - Ferencz, Viktória AU - Tabák, Ádám ED - Takács, István TI - Nephropathia diabetica T2 - Belgyógyászat 1 tantárgyi jegyzet PB - Semmelweis Kiadó CY - Budapest SN - 9789633316122 PY - 2024 SP - 139 EP - 139 PG - 1 UR - https://m2.mtmt.hu/api/publication/34804467 ID - 34804467 LA - Hungarian DB - MTMT ER -