@article{MTMT:34824725,
	title = {Trends and regional differences in antidiabetic medication use: a nationwide retrospective observational study},
	url = {https://m2.mtmt.hu/api/publication/34824725},
	author = {Csatordai, Márta and Benkő, Ria and Matuz, Mária and Engi, Zsófia and Csupor, Dezső and Lengyel, Csaba Attila and Doró, Péter},
	doi = {10.1186/s13098-024-01334-8},
	journal-iso = {DIABETOL METAB SYNDR},
	journal = {DIABETOLOGY AND METABOLIC SYNDROME},
	volume = {16},
	unique-id = {34824725},
	issn = {1758-5996},
	year = {2024},
	eissn = {1758-5996},
	orcid-numbers = {Benkő, Ria/0000-0002-8009-8962; Matuz, Mária/0000-0002-7877-2399; Csupor, Dezső/0000-0002-4088-3333; Lengyel, Csaba Attila/0000-0002-0434-0067; Doró, Péter/0000-0001-7784-6010}
}

@article{MTMT:34796471,
	title = {Favipiravir does not improve viral clearance in mild to moderate COVID-19 – a systematic review and meta-analysis of randomized controlled trials},
	url = {https://m2.mtmt.hu/api/publication/34796471},
	author = {Bahar, Muhammad Akbar and Kusuma, Ikhwan Yuda and Visnyovszki, Ádám and Matuz, Mária and Benkő, Ria and Ferenci, Tamás and Szabó, Bálint Gergely and Hajdú, Edit and Pető, Zoltán and Csupor, Dezső},
	doi = {10.1016/j.heliyon.2024.e29808},
	journal-iso = {HELIYON},
	journal = {HELIYON},
	volume = {10},
	unique-id = {34796471},
	year = {2024},
	eissn = {2405-8440},
	orcid-numbers = {Matuz, Mária/0000-0002-7877-2399; Benkő, Ria/0000-0002-8009-8962; Ferenci, Tamás/0000-0001-6791-3080; Szabó, Bálint Gergely/0000-0003-1775-1356; Csupor, Dezső/0000-0002-4088-3333}
}

@article{MTMT:34791311,
	title = {Pain management: opioid use in hospitals},
	url = {https://m2.mtmt.hu/api/publication/34791311},
	author = {Dewi, Ni Made Amelia Ratnata and Benkő, Ria and Engi, Zsófia and Csupor, Dezső and Viola, Réka and Csatordai, Márta and Matuz, Mária},
	doi = {10.1136/ejhpharm-2024-eahp.501},
	journal-iso = {EUR J HOSP PHARM SCI PRACT},
	journal = {EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE},
	volume = {31},
	unique-id = {34791311},
	issn = {2047-9956},
	year = {2024},
	eissn = {2047-9964},
	pages = {A242-A243},
	orcid-numbers = {Benkő, Ria/0000-0002-8009-8962; Csupor, Dezső/0000-0002-4088-3333; Matuz, Mária/0000-0002-7877-2399}
}

@article{MTMT:34728728,
	title = {Storage Conditions Influence the Quality of Ginger – A Stability Study Inspired by Clinical Trials},
	url = {https://m2.mtmt.hu/api/publication/34728728},
	author = {Tóth, Barbara and Horváth, Attila and Jójártné Laczkovich, Orsolya and Biró, Dalma and Matuz, Mária and Csupor, Dezső},
	doi = {10.1055/a-2283-8147},
	journal-iso = {PLANTA MED},
	journal = {PLANTA MEDICA: NATURAL PRODUCTS AND MEDICINAL PLANT RESEARCH},
	unique-id = {34728728},
	issn = {0032-0943},
	abstract = {Ginger has traditionally been used to treat and prevent nausea and vomiting; however, the results of clinical trials are ambiguous. The efficacy of ginger is attributed to gingerols and their metabolites, shogaols. Since these compounds have different pharmacological profiles, the clinical efficacy of ginger products is largely dependent on their chemical composition. The goal of our study was to examine the stability of ginger determining the 6-gingerol contents in order to assess the effects of different storage conditions. We have performed a 6-month stability test with dry ginger rhizome samples stored in a constant climate chamber in three different storage containers (uncovered glass container, glass container sealed with rubber stopper, plastic container). 6-gingerol contents were measured by HPLC method. The concentration of 6-gingerol decreased in all samples. In the sealed glass container, the decrease of 6-gingerol content was significantly lower than in the unsealed glass container and in the plastic container. These results demonstrate that storage conditions have a significant impact on the quality of ginger, which may also affect efficacy.},
	year = {2024},
	eissn = {1439-0221},
	orcid-numbers = {Tóth, Barbara/0000-0002-6086-8819; Matuz, Mária/0000-0002-7877-2399; Csupor, Dezső/0000-0002-4088-3333}
}

@article{MTMT:34721808,
	title = {Correlation between Stenotrophomonas maltophilia incidence and systemic antibiotic use: A 10-year retrospective, observational study in Hungary},
	url = {https://m2.mtmt.hu/api/publication/34721808},
	author = {Gajdács, Márió and Matuz, Mária and Benkő, Ria and Pető, Zoltán and Hajdú, Edit},
	doi = {10.1556/1886.2024.00022},
	journal-iso = {EUR J MICROBIOL IMMU},
	journal = {EUROPEAN JOURNAL OF MICROBIOLOGY AND IMMUNOLOGY},
	unique-id = {34721808},
	issn = {2062-509X},
	abstract = {Extensive use of carbapenems may lead to selection pressure for Stenotrophomonas maltophilia (SM) in hospital environments. The aim of our study was to assess the possible association between systemic antibiotic use and the incidence of SM. A retrospective, observational study was carried out in a tertiary-care hospital in Hungary, between January 1st 2010 and December 31st 2019. Incidence-density for SM and SM resistant to trimethoprim-sulfamethoxazole (SXT) was standardized for 1000 patient-days, while systemic antibiotic use was expressed as defined daily doses (DDDs) per 100 patient-days. Mean incidence density for SM infections was 0.42/1000 patient-days; 11.08% were were resistant to SXT, the mean incidence density for SXT-resistant SM was 0.047/1000 patient-days. Consumption rate for colistin, glycopeptides and carbapenems increased by 258.82, 278.94 and 372.72% from 2010 to 2019, respectively. Strong and significant positive correlations were observed with the consumption of carbapenems (r: 0.8759; P < 0.001 and r: 0.8968; P < 0.001), SXT (r: 0.7552; P = 0.011 and r: 0.7004; P  = 0.024), and glycopeptides (r: 0.7542; P = 0.012 and r: 0.8138; P < 0.001) with SM and SXT-resistant SM incidence-density/1000 patient-days, respectively. Implementation of institutional carbapenem-sparing strategies are critical in preserving these life-saving drugs, and may affect the microbial spectrum of infections in clinical settings.},
	year = {2024},
	eissn = {2062-8633},
	orcid-numbers = {Gajdács, Márió/0000-0003-1270-0365; Matuz, Mária/0000-0002-7877-2399; Benkő, Ria/0000-0002-8009-8962}
}

@article{MTMT:34577678,
	title = {Antibiotic knowledge assessment questionnaire in undergraduate pharmacy students: A Rasch analysis of validity evidence},
	url = {https://m2.mtmt.hu/api/publication/34577678},
	author = {Kusuma, Ikhwan Yuda and Bahar, Muhammad Akbar and Nuari, Doni Anshar and Prabandari, Rani and Soeharto, Soeharto and Csupor, Dezső and Benkő, Ria and Matuz, Mária},
	doi = {10.46542/pe.2024.241.5478},
	journal-iso = {PHARM EDUC},
	journal = {PHARMACY EDUCATION},
	volume = {24},
	unique-id = {34577678},
	issn = {1560-2214},
	abstract = {Background: Antibiotic knowledge is crucial for undergraduate pharmacy students who are future healthcare professionals. However, a valid and reliable instrument to assess their knowledge is scarce. This study aimed to develop and validate an Antibiotic Knowledge Assessment Questionnaire (AKAQ).Methods: The AKAQ had three domains and 29 items, encompassing general antibiotic knowledge, antibiotic resistance, and antibiotic stewardship. Rasch analysis was used to assess psychometric properties, including validity parameters (item and person fit and structural validity), reliability (person and item reliability, Cronbach’s Alpha value), item-person interaction, and item bias, using differential item functioning (DIF) based on tems.Results: This study included 500 undergraduate pharmacy students from 90 Indonesian universities. The validity of the questionnaire was demonstrated, except for one item. Person means infit and outfit for MNSQ were 1.02 and 0.95, whereas ZSTD were 0.11 and 0.08, respectively. Items means infit and outfit for MNSQ were 1.01 and 0.96, while ZSTD were 0.11 and -0.23. Item and person reliabilities were acceptable at 0.99 and 0.68. Cronbach’s alpha reliability was acceptable at 0.71. Two items were biased by term.Conclusion: The AKAQ is a valid, reliable, and standard instrument for assessing the antibiotic knowledge levels of undergraduate pharmacy students.},
	year = {2024},
	eissn = {1477-2701},
	pages = {54-78},
	orcid-numbers = {Csupor, Dezső/0000-0002-4088-3333; Benkő, Ria/0000-0002-8009-8962; Matuz, Mária/0000-0002-7877-2399}
}

@article{MTMT:34532941,
	title = {Hospital Antibiotic Consumption before and during the COVID-19 Pandemic in Hungary},
	url = {https://m2.mtmt.hu/api/publication/34532941},
	author = {Ruzsa, Roxána and Benkő, Ria and Hambalek, Helga and Papfalvi, Erika Piroska and Csupor, Dezső and Nacsa, Róbert and Csatordai, Márta and Soós, Gyöngyvér and Hajdú, Edit and Matuz, Mária},
	doi = {10.3390/antibiotics13010102},
	journal-iso = {ANTIBIOTICS-BASEL},
	journal = {ANTIBIOTICS},
	volume = {13},
	unique-id = {34532941},
	abstract = {The aim of this study was to assess antibiotic use in the Hungarian hospital care sector during and before the pandemic. Aggregated systemic antibiotic (ATC: J01) utilisation data were obtained for the 2010–2021 period. Classifications and calculations were performed according to the WHO ATC/DDD index and expressed as DDD per 1000 inhabitants and per day (DID), DDD per 100 patient-days (DHPD) and DDD/discharge. A linear regression (trend analysis) was performed for the pre-COVID years (2010–2019) and a prediction interval was set up to assess whether the pandemic years’ observed utilisation fit in. Antibiotic utilisation was constant in DID before and during the pandemic (2019: 1.16; 2020: 1.21), while we observed a substantial increase in antibiotic use when expressed in DDD per 100 patient-days (2019: 23.3, 2020: 32.2) or DDD/discharge (2019: 1.83, 2020: 2.45). The observed utilisation level of penicillin combinations; first-, third- and fourth-generation cephalosporins; carbapenems; glycopeptides; nitroimidazoles and macrolides exceeded the predicted utilisation values in both pandemic years. Before the pandemic, co-amoxiclav headed the top list of antibiotic use, while during the pandemic, ceftriaxone became the most widely used antibiotic. Azithromycin moved up substantially on the top list of antibiotic use, with a 397% increase (2019: 0.45; 2020: 2.24 DHPD) in use. In summary, the pandemic had a major impact on the scale and pattern of hospital antibiotic use in Hungary.},
	year = {2024},
	eissn = {2079-6382},
	orcid-numbers = {Benkő, Ria/0000-0002-8009-8962; Csupor, Dezső/0000-0002-4088-3333; Matuz, Mária/0000-0002-7877-2399}
}

@CONFERENCE{MTMT:34500723,
	title = {Stenotrophomonas maltophilia epidemiológiája és az antibiotikum-fogyasztás közötti összefüggések: 10-éves korrelációs vizsgálat},
	url = {https://m2.mtmt.hu/api/publication/34500723},
	author = {Gajdács, Márió and Benkő, Ria and Matuz, Mária and Bodó, Gabriella and Pető, Zoltán and Hajdú, Edit},
	booktitle = {XV. Fiatal Higiénikusok Fóruma: Program és összefoglalók},
	unique-id = {34500723},
	year = {2023},
	pages = {12-12},
	orcid-numbers = {Gajdács, Márió/0000-0003-1270-0365; Benkő, Ria/0000-0002-8009-8962; Matuz, Mária/0000-0002-7877-2399}
}

@article{MTMT:34413320,
	title = {Evaluation of the Diagnosis and Antibiotic Prescription Pattern in Patients Hospitalized with Urinary Tract Infections: Single-Center Study from a University-Affiliated Hospital},
	url = {https://m2.mtmt.hu/api/publication/34413320},
	author = {Fésüs, Adina and Matuz, Mária and Papfalvi, Erika Piroska and Hambalek, Helga and Ruzsa, Roxána and Tánczos, Bence and Bácskay, Ildikó and Lekli, István and Illés, Árpád and Benkő, Ria},
	doi = {10.3390/antibiotics12121689},
	journal-iso = {ANTIBIOTICS-BASEL},
	journal = {ANTIBIOTICS},
	volume = {12},
	unique-id = {34413320},
	abstract = {UTIs (urinary tract infections) are common bacterial infections with a non-negligible hospitalization rate. The diagnosis of UTIs remains a challenge for prescribers and a common source of misdiagnosis. This retrospective observational study aimed to evaluate whether recorded diagnosis by clinicians and empirical antibiotic therapy met the EAU (European Association of Urology) guideline in patients hospitalized with UTI. The study was conducted at an internal medicine unit of a tertiary care medical center in Hungary. The diagnosis was assessed based on clinical presentation, physical examination, and laboratory (including microbiological) results, considering all the potential risk factors. Diagnosis was considered misdiagnosis when not confirmed by clinical presentation or clinical signs and symptoms. Evaluation of empirical antibiotic therapy was performed only for confirmed UTIs. Empirical treatment was considered guideline-adherent when complying with the relevant recommendations. Out of 185 patients, 41.6% failed to meet EAU-based UTI diagnosis criteria, of which 27.6% were misdiagnosed and 14.1% were ABU (asymptomatic bacteriuria). The diagnosis of urosepsis recorded at admission (9.7%, 18/185) was not confirmed either by clinical or microbiological tests in five (5/18) cases. The initial empirical therapies for UTI showed a relatively low rate (45.4%) of guideline adherence regarding agent selection. The most common guideline-non-adherent therapies were combinations with metronidazole (16.7%). Dosage appropriateness assessments showed a guideline adherence rate of 36.1%, and underdosing due to high body weight was common (9.3%). Overall (agent, route of administration, dose, duration) guideline adherence was found to be substantially low (10.2%). We found a relatively high rate of misdiagnosed UTIs. Written protocols on the ward may be crucial in reducing misdiagnosis and in optimizing antibiotic use.},
	year = {2023},
	eissn = {2079-6382},
	orcid-numbers = {Fésüs, Adina/0000-0002-6351-7715; Matuz, Mária/0000-0002-7877-2399; Lekli, István/0000-0002-0992-4176; Benkő, Ria/0000-0002-8009-8962}
}

@article{MTMT:34398418,
	title = {Gyógyszeres szülésindukció, gyógyszeres tocolysis: helyi gyakorlat vs. Nemzetközi protokollok [Labor induction and tocolysis: local practice versus international guidelines]},
	url = {https://m2.mtmt.hu/api/publication/34398418},
	author = {Szemán, Ágnes and Matuz, Mária and Benkő, Ria},
	journal-iso = {ACTA PHARM HUNG},
	journal = {ACTA PHARMACEUTICA HUNGARICA},
	volume = {93},
	unique-id = {34398418},
	issn = {0001-6659},
	year = {2023},
	eissn = {1587-1495},
	pages = {S72-S72},
	orcid-numbers = {Matuz, Mária/0000-0002-7877-2399; Benkő, Ria/0000-0002-8009-8962}
}