@article{MTMT:31256609,
	title = {The neural tissue around SU-8 implants: A quantitative in vivo biocompatibility study},
	url = {https://m2.mtmt.hu/api/publication/31256609},
	author = {Márton, Gergely and Tóth, Estilla Zsófia and Wittner, Lucia and Fiáth, Richárd and Pinke, Domonkos Péter and Orbán, Gábor and Meszéna, Domokos and Pál, Ildikó and Győri, Edit Lelle and Bereczki, Zsófia and Kandrács, Ágnes and Hofer, Katharina and Pongrácz, Anita and Ulbert, István and Tóth, Kinga},
	doi = {10.1016/j.msec.2020.110870},
	journal-iso = {MAT SCI ENG C-MATER},
	journal = {MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS},
	volume = {112},
	unique-id = {31256609},
	issn = {0928-4931},
	year = {2020},
	eissn = {1873-0191},
	orcid-numbers = {Wittner, Lucia/0000-0001-6800-0953; Fiáth, Richárd/0000-0001-8732-2691; Meszéna, Domokos/0000-0003-4042-2542; Pál, Ildikó/0000-0003-2124-9967; Kandrács, Ágnes/0000-0002-6408-2397; Pongrácz, Anita/0000-0001-6793-8739; Ulbert, István/0000-0001-9941-9159; Tóth, Kinga/0000-0002-8751-8499}
}

@article{MTMT:30733372,
	title = {A silicon-based spiky probe providing improved cell accessibility during in vitro slice recordings},
	url = {https://m2.mtmt.hu/api/publication/30733372},
	author = {Meszéna, Domokos and Kerekes, Bálint Péter and Pál, Ildikó and Orbán, Gábor and Fiáth, Richárd and Holzhammer, Tobias and Ruther, Patrick and Ulbert, István and Márton, Gergely},
	doi = {10.1016/j.snb.2019.126649},
	journal-iso = {SENSOR ACTUAT B CHEM},
	journal = {SENSORS AND ACTUATORS B-CHEMICAL},
	volume = {297},
	unique-id = {30733372},
	issn = {0925-4005},
	year = {2019},
	eissn = {0925-4005},
	orcid-numbers = {Meszéna, Domokos/0000-0003-4042-2542; Kerekes, Bálint Péter/0000-0001-9542-8082; Pál, Ildikó/0000-0003-2124-9967; Fiáth, Richárd/0000-0001-8732-2691; Ruther, Patrick/0000-0002-7358-003X; Ulbert, István/0000-0001-9941-9159}
}

@article{MTMT:3130167,
	title = {Neurobiochemical changes in the vicinity of a nanostructured neural implant},
	url = {https://m2.mtmt.hu/api/publication/3130167},
	author = {Bérces, Zsófia and Tóth, Kinga and Márton, Gergely and Pál, Ildikó and Kováts-Megyesi, B and Fekete, Zoltán and Ulbert, István and Pongrácz, Anita},
	doi = {10.1038/srep35944},
	journal-iso = {SCI REP},
	journal = {SCIENTIFIC REPORTS},
	volume = {6},
	unique-id = {3130167},
	issn = {2045-2322},
	year = {2016},
	eissn = {2045-2322},
	orcid-numbers = {Tóth, Kinga/0000-0002-8751-8499; Pál, Ildikó/0000-0003-2124-9967; Fekete, Zoltán/0000-0002-6718-4022; Ulbert, István/0000-0001-9941-9159; Pongrácz, Anita/0000-0001-6793-8739}
}

@mastersthesis{MTMT:2984591,
	title = {Idegi aktivitás térbeli követésére alkalmazott optikai jelek molekuláris komponenseinek azonosítása},
	url = {https://m2.mtmt.hu/api/publication/2984591},
	author = {Pál, Ildikó},
	doi = {10.15476/ELTE.2015.023},
	publisher = {Eötvös Loránd University},
	unique-id = {2984591},
	keywords = {Doktori disszertáció; KÖZPONTI IDEGRENDSZER; képalkotó eljárások; ingerületátvitel mérés; hippokampusz},
	year = {2015},
	orcid-numbers = {Pál, Ildikó/0000-0003-2124-9967}
}

@article{MTMT:2972587,
	title = {Appearance of fast astrocytic component in voltage-sensitive dye imaging of neural activity},
	url = {https://m2.mtmt.hu/api/publication/2972587},
	author = {Pál, Ildikó and Kardos, Julianna and Dobolyi, Árpád and Héja, László},
	doi = {10.1186/s13041-015-0127-9},
	journal-iso = {MOL BRAIN},
	journal = {MOLECULAR BRAIN},
	volume = {8},
	unique-id = {2972587},
	issn = {1756-6606},
	abstract = {BACKGROUND: Voltage-sensitive dye (VSD) imaging and intrinsic optical signals (IOS) are widely used methods for monitoring spatiotemporal neural activity in extensive networks. In spite of that, identification of their major cellular and molecular components has not been concluded so far. RESULTS: We addressed these issues by imaging spatiotemporal spreading of IOS and VSD transients initiated by Schaffer collateral stimulation in rat hippocampal slices with temporal resolution comparable to standard field potential recordings using a 464-element photodiode array. By exploring the potential neuronal and astroglial molecular players in VSD and IOS generation, we identified multiple astrocytic mechanisms that significantly contribute to the VSD signal, in addition to the expected neuronal targets. Glutamate clearance through the astroglial glutamate transporter EAAT2 has been shown to be a significant player in VSD generation within a very short (<5 ms) time-scale, indicating that astrocytes do contribute to the development of spatiotemporal VSD transients previously thought to be essentially neuronal. In addition, non-specific anion channels, astroglial K(+) clearance through Kir4.1 channel and astroglial Na(+)/K(+) ATPase also contribute to IOS and VSD transients. CONCLUSION: VSD imaging cannot be considered as a spatially extended field potential measurement with predominantly neuronal origin, instead it also reflects a fast communication between neurons and astrocytes.},
	year = {2015},
	eissn = {1756-6606},
	orcid-numbers = {Pál, Ildikó/0000-0003-2124-9967; Dobolyi, Árpád/0000-0003-0397-2991}
}

@article{MTMT:2743439,
	title = {The hippocampal CA3 region can generate two distinct types of sharp wave-ripple complexes, in vitro.},
	url = {https://m2.mtmt.hu/api/publication/2743439},
	author = {Hofer, Katharina and Kandrács, Ágnes and Ulbert, István and Pál, Ildikó and Szabó, Csilla and Héja, László and Wittner, Lucia},
	doi = {10.1002/hipo.22361},
	journal-iso = {HIPPOCAMPUS},
	journal = {HIPPOCAMPUS},
	volume = {25},
	unique-id = {2743439},
	issn = {1050-9631},
	abstract = {Hippocampal sharp wave-ripples (SPW-Rs) occur during slow wave sleep and behavioral immobility and are thought to play an important role in memory formation. We investigated the cellular and network properties of SPW-Rs with simultaneous laminar multielectrode and intracellular recordings in a rat hippocampal slice model, using physiological bathing medium. Spontaneous SPW-Rs were generated in the dentate gyrus (DG), CA3 and CA1 regions. These events were characterized by a local field potential gradient (LFPg) transient, increased fast oscillatory activity and increased multiple unit activity (MUA). Two types of SPW-Rs were distinguished in the CA3 region based on their different LFPg and current source density (CSD) pattern. Type 1 (T1) displayed negative LFPg transient in the pyramidal cell layer, and the associated CSD sink was confined to the proximal dendrites. Type 2 (T2) SPW-Rs were characterized by positive LFPg transient in the cell layer, and showed CSD sinks involving both the apical and basal dendrites. In both types, consistent with the somatic CSD source, only a small subset of CA3 pyramidal cells fired, most pyramidal cells were hyperpolarized, while most interneurons increased firing rate before the LFPg peak. Different neuronal populations, with different proportions of pyramidal cells and distinct subsets of interneurons were activated during T1 and T2 SPW-Rs. Activation of specific inhibitory cell subsets - with the possible leading role of perisomatic interneurons - seems to be crucial to synchronize distinct ensembles of CA3 pyramidal cells finally resulting in the expression of different SPW-R activities. This suggests that the hippocampus can generate dynamic changes in its activity stemming from the same excitatory and inhibitory circuits, and so, might provide the cellular and network basis for an input-specific and activity-dependent information transmission. (c) 2014 Wiley Periodicals, Inc.},
	year = {2015},
	eissn = {1098-1063},
	pages = {169-186},
	orcid-numbers = {Kandrács, Ágnes/0000-0002-6408-2397; Ulbert, István/0000-0001-9941-9159; Pál, Ildikó/0000-0003-2124-9967; Wittner, Lucia/0000-0001-6800-0953}
}

@article{MTMT:2305528,
	title = {Sodium selective ion channel formation in living cell membranes by polyamidoamine dendrimer},
	url = {https://m2.mtmt.hu/api/publication/2305528},
	author = {Nyitrai, Gabriella and Keszthelyi, Tamás and Bóta, Attila and Simon, Ágnes and Tőke, Orsolya and Horváth, Gergő and Pál, Ildikó and Kardos, Julianna and Héja, László},
	doi = {10.1016/j.bbamem.2013.04.004},
	journal-iso = {BBA-BIOMEMBRANES},
	journal = {BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES},
	volume = {1828},
	unique-id = {2305528},
	issn = {0005-2736},
	year = {2013},
	eissn = {1879-2642},
	pages = {1873-1880},
	orcid-numbers = {Pál, Ildikó/0000-0003-2124-9967}
}

@article{MTMT:2305501,
	title = {Polyamidoamine dendrimer impairs mitochondrial oxidation in brain tissue},
	url = {https://m2.mtmt.hu/api/publication/2305501},
	author = {Nyitrai, Gabriella and Héja, László and Jablonkai, István and Pál, Ildikó and Benéné Visy, Júlia and Kardos, Julianna},
	doi = {10.1186/1477-3155-11-9},
	journal-iso = {J NANOBIOTECHNOL},
	journal = {JOURNAL OF NANOBIOTECHNOLOGY},
	volume = {11},
	unique-id = {2305501},
	abstract = {Background: The potential nanocarrier polyamidoamine (PAMAM) generation 5 (G5-NH2) dendrimer has been shown to evoke lasting neuronal depolarization and cell death in a concentration-dependent manner. In this study we explored the early progression of G5-NH2 action in brain tissue on neuronal and astroglial cells.Results: In order to describe early mechanisms of G5-NH2 dendrimer action in brain tissue we assessed G5-NH2 trafficking, free intracellular Ca2+ and mitochondrial membrane potential (ΨMITO) changes in the rat hippocampal slice by microfluorimetry. With the help of fluorescent dye conjugated G5-NH2, we observed predominant appearance of the dendrimer in the plasma membrane of pyramidal neurons and glial cells within 30 min. Under this condition, G5-NH2 evoked robust intracellular Ca2+ enhancements and ΨMITO depolarization both in pyramidal neurons and astroglial cells. Intracellular Ca2+ enhancements clearly preceded ΨMITO depolarization in astroglial cells. Comparing activation dynamics, neurons and glia showed prevalence of lasting and transient ΨMITO depolarization, respectively. Transient as opposed to lasting ΨMITO changes to short-term G5-NH2 application suggested better survival of astroglia, as observed in the CA3 stratum radiatum area. We also showed that direct effect of G5-NH2 on astroglial ΨMITO was significantly enhanced by neuron-astroglia interaction, subsequent to G5-NH2 evoked neuronal activation.Conclusion: These findings indicate that the interaction of the PAMAM dendrimer with the plasma membrane leads to robust activation of neurons and astroglial cells, leading to mitochondrial depolarization. Distinguishable dynamics of mitochondrial depolarization in neurons and astroglia suggest that the enhanced mitochondrial depolarization followed by impaired oxidative metabolism of neurons may be the primary basis of neurotoxicity. © 2013 Nyitrai et al.; licensee BioMed Central Ltd.},
	keywords = {brain tissue; Nanotoxicity; PAMAM dendrimer; Mitochondrial depolarization; Calcium enhancement},
	year = {2013},
	eissn = {1477-3155},
	orcid-numbers = {Pál, Ildikó/0000-0003-2124-9967}
}

@article{MTMT:2222611,
	title = {Neuronal and Astroglial Correlates Underlying Spatiotemporal Intrinsic Optical Signal in the Rat Hippocampal Slice},
	url = {https://m2.mtmt.hu/api/publication/2222611},
	author = {Pál, Ildikó and Nyitrai, Gabriella and Kardos, Julianna and Héja, László},
	doi = {10.1371/journal.pone.0057694},
	journal-iso = {PLOS ONE},
	journal = {PLOS ONE},
	volume = {8},
	unique-id = {2222611},
	issn = {1932-6203},
	year = {2013},
	eissn = {1932-6203},
	orcid-numbers = {Pál, Ildikó/0000-0003-2124-9967}
}

@article{MTMT:2060849,
	title = {Assessing toxicity of polyamidoamine dendrimers by neuronal signaling functions},
	url = {https://m2.mtmt.hu/api/publication/2060849},
	author = {Nyitrai, Gabriella and Kékesi, Orsolya Sára and Pál, Ildikó and Keglevich, Péter and Csíki, Zsuzsanna and Fügedi, Péter and Simon, Ágnes and Fitos, Ilona and Németh, Krisztina and Benéné Visy, Júlia and Tárkányi, Gábor and Kardos, Julianna},
	doi = {10.3109/17435390.2011.591511},
	journal-iso = {NANOTOXICOLOGY},
	journal = {NANOTOXICOLOGY},
	volume = {6},
	unique-id = {2060849},
	issn = {1743-5390},
	keywords = {Brain; CELLS; DELIVERY; GROWTH; CYTOTOXICITY; NANOPARTICLES; Phosphate; internalization; MOLECULAR SIMULATION; CARRIERS; PAMAM dendrimers; imaging cell death; beta-D-glucopyranose-conjugation; polycationic and polyanionic PAMAM dendrimers; Functional neurotoxicity indicators},
	year = {2012},
	eissn = {1743-5404},
	pages = {576-586},
	orcid-numbers = {Pál, Ildikó/0000-0003-2124-9967}
}