TY - JOUR AU - Hernádfői , Márk Viktor AU - Koch, Dóra Kornélia AU - Kói, Tamás AU - Imrei, Marcell AU - Nagy, Rita AU - Máté, Vanda AU - Garai, Réka AU - Donnet, Jessica AU - Balogh, József AU - Kovács, Gábor AU - Párniczky, Andrea AU - Hegyi, Péter AU - Garami, Miklós TI - Burden of Childhood Cancer and the Social and Economic Challenges in Adulthood JF - JAMA PEDIATRICS J2 - JAMA PEDIATR VL - in PY - 2024 IS - press SN - 2168-6203 DO - 10.1001/jamapediatrics.2024.0642 UR - https://m2.mtmt.hu/api/publication/34792056 ID - 34792056 N1 - Funding Agency and Grant Number: Ministry for Innovation and Technology funded by the National Research, Development, and Innovation Fund Funding text: No Statement Available LA - English DB - MTMT ER - TY - JOUR AU - Ferencsikné Kéri, Adrienn Krisztina AU - Bajzát, Dorina Rita AU - Andrásdi, Zita AU - Juhász, Márk Félix AU - Nagy, Rita AU - Kói, Tamás AU - Kovács, Gábor AU - Hegyi, Péter AU - Párniczky, Andrea TI - Early onset of abnormal glucose tolerance in patients with cystic fibrosis : A systematic review and meta-analysis JF - JOURNAL OF CYSTIC FIBROSIS J2 - J CYST FIBROS PY - 2024 SN - 1569-1993 DO - 10.1016/j.jcf.2024.02.010 UR - https://m2.mtmt.hu/api/publication/34729555 ID - 34729555 AB - Despite translational evidences suggesting that cystic fibrosis-related abnormal glucose tolerance (CF-related AGT) may begin early in life and is known to be associated with increased morbidity and mortality, current guidelines recommend screening for AGT only from 10 years of age, thus missing the opportunity for early detection and intervention.A systematic review and meta-analysis (PROSPERO number: CRD42021282516) was conducted on studies that reported data on the prevalence of AGT or its subtypes in CF populations. Pooled proportions, risk, and odds ratios with 95 % confidence intervals (CI) were calculated. One-stage dose-response random-effect meta-analysis was used to assess the effect of age on CF-related diabetes (CFRD).The quantitative analysis included 457 studies and data from 520,544 patients. Every third child with CF (chwCF) (0.31 [95 % CI 0.25-0.37]) and every second adult with CF (awCF) (0.51 [95 % CI 0.45-0.57]) were affected by AGT. Even in the 5-10 years of age subgroup, the proportion of AGT was 0.42 [95 % CI 0.34-0.51]. The prevalence of prediabetes remained unchanged (impaired glucose tolerance in chwCF:0.14 [95 % CI 0.10-0.18]) vs. awCF:0.19 [95 % CI 0.14-0.25]), whereas the proportion of CFRD increased with age (0-5: 0.005 [95 % CI 0.0001-0.15]; 5-10: 0.05 [95 % CI 0.01-0.27]; 10-18: 0.11 [95 % CI 0.08-0.14]; >18 years of age: 0.27 [95 % CI 0.24-0.30]).CF-related AGT is common under 10 years of age. Our study suggests considering earlier AGT screening, starting from 5 years of age. This highlights the imperative for additional research for guideline adjustments and provides the opportunity for early intervention. LA - English DB - MTMT ER - TY - CHAP AU - Párniczky, Andrea ED - Tulassay, Tivadar TI - Krónikus pancreatitis T2 - Klinikai gyermekgyógyászat PB - Medicina Könyvkiadó CY - Budapest SN - 9789632286673 PY - 2024 SP - 631 EP - 632 PG - 2 UR - https://m2.mtmt.hu/api/publication/34688862 ID - 34688862 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Tímár, Ágnes Eszter AU - Párniczky, Andrea AU - Budai, Kinga Anna AU - Hernádfői , Márk Viktor AU - Kasznár, Emese AU - Varga, Péter AU - Hegyi, Péter AU - Váncsa, Szilárd AU - Tóth, Réka AU - Veres, Dániel AU - Garami, Miklós AU - Müller, Katalin Eszter TI - Beyond the Gut: A Systematic Review and Meta-analysis of Advanced Therapies for Inflammatory Bowel Disease-associated Extraintestinal Manifestations JF - JOURNAL OF CROHNS & COLITIS J2 - J CROHNS COLITIS PY - 2024 SN - 1873-9946 DO - 10.1093/ecco-jcc/jjae002 UR - https://m2.mtmt.hu/api/publication/34498800 ID - 34498800 LA - English DB - MTMT ER - TY - JOUR AU - Nagy, Rita AU - Ocskay, Klementina AU - Sipos, Zoltán AU - Szentesi, Andrea Ildikó AU - Vincze, Áron AU - Czakó, László AU - Izbéki, Ferenc AU - Shirinskaya, Natalia V AU - Poluektov, Vladimir L AU - Zolotov, Alexandr N AU - Zhu, Yin AU - Xia, Liang AU - He, Wenhua AU - Sutton, Robert AU - Szatmary, Peter AU - Mukherjee, Rajarshi AU - Burridge, Isobel Saffron AU - Wauchope, Emma AU - Francisco, Elsa AU - Aparicio, David AU - Pinto, Bruno AU - Gomes, António AU - Nunes, Vitor AU - Tantau, Vasile Marcel AU - Sagau, Emanuela Denisa AU - Tantau, Alina Ioana AU - Suceveanu, Andra Iulia AU - Tocia, Cristina AU - Dumitru, Andrei AU - Pando, Elizabeth AU - Alberti, Piero AU - Cirera, Arturo AU - Molero, Xavier AU - Lee, Hong Sik AU - Jung, Min Kyu AU - Kim, Eui Joo AU - Lee, Sanghyub AU - Rebollo, María Lourdes Ruiz AU - Nistal, Reyes Busta AU - Santervas, Sandra Izquierdo AU - Lesko, Dusan AU - Soltes, Marek AU - Radonak, Jozef AU - Zatorski, Hubert AU - Małecka-Panas, Ewa AU - Fabisiak, Adam AU - Yaroslav, M Susak AU - Mykhailo, V Maksymenko AU - Olekcandr, A Tkachenko AU - Barauskas, Giedrius AU - Simanaitis, Vytautas AU - Ignatavicius, Povilas AU - Jinga, Mariana AU - Balaban, Vasile-Daniel AU - Patoni, Cristina AU - Gong, Liang AU - Song, Kai AU - Li, Yunlong AU - Gonçalves, T Cúrdia AU - Freitas, Marta AU - Macedo, Vítor AU - Vornhuelz, Marlies AU - Klauss, Sarah AU - Beyer, Georg AU - Koksal, Aydin Seref AU - Tozlu, Mukaddes AU - Eminler, Ahmet Tarik AU - Monclús, Nuria Torres AU - Comas, Eva Pijoan AU - Oballe, Juan Armando Rodriguez AU - Nawacki, Łukasz AU - Głuszek, Stanisław AU - Rama-Fernández, Alberto AU - Galego, Marco AU - de la Iglesia, Daniel AU - Aykut, Umut Emre AU - Duman, Deniz Güney AU - Aslan, Rahmi AU - Gherbon, Adriana AU - Deng, Lihui AU - Huang, Wei AU - Xia, Qing AU - Poropat, Goran AU - Radovan, Anja AU - Vranić, Luka AU - Ricci, Claudio AU - Ingaldi, Carlo AU - Casadei, Riccardo AU - Negoi, Ionut AU - Ciubotaru, Cezar AU - Iordache, Florin Mihail AU - Constantinescu, Gabriel AU - Sandru, Vasile AU - Altintas, Engin AU - Balci, Hatice Rizaoglu AU - Constantino, Júlio AU - Aveiro, Débora AU - Pereira, Jorge AU - Gunay, Suleyman AU - Misirlioglu Sucan, Seda AU - Dronov, Oleksiy AU - Kovalska, Inna AU - Bush, Nikhil AU - Rana, Surinder Singh AU - Chooklin, Serge AU - Chuklin, Serhii AU - Saizu, Ionut Adrian AU - Gheorghe, Cristian AU - Göltl, Philipp AU - Hirth, Michael AU - Mateescu, Radu Bogdan AU - Papuc, Geanina AU - Minkov, Georgi Angelov AU - Enchev, Emil Tihomirov AU - Mastrangelo, Laura AU - Jovine, Elio AU - Chen, Weiwei AU - Zhu, Quping AU - Gąsiorowska, Anita AU - Fabisiak, Natalia AU - Bezmarevic, Mihailo AU - Litvin, Andrey AU - Mottes, Martina Cattani AU - Choi, Eun Kwang AU - Bánovčin, Peter AU - Nosáková, Lenka AU - Kovacheva-Slavova, Mila Dimitrova AU - Kchaou, Ali AU - Tlili, Ahmed AU - Marino, Marco V AU - Kusnierz, Katarzyna AU - Mickevicius, Artautas AU - Hollenbach, Marcus AU - Molcan, Pavol AU - Ioannidis, Orestis AU - Tokarev, Mark Valerievich AU - Ince, Ali Tüzün AU - Semenenko, Ivan Albertovich AU - Galeev, Shamil AU - Ramírez-Maldonado, Elena AU - Sallinen, Ville AU - Pencik, Petr AU - Bajor, Judit AU - Sarlós, Patrícia AU - Hágendorn, Roland AU - Gódi, Szilárd AU - Szabó, Imre AU - Czimmer, József AU - Pár, Gabriella AU - Illés, Anita AU - Faluhelyi, Nándor AU - Kanizsai, Péter László AU - Nagy, Tamás AU - Mikó, Alexandra AU - Németh, Balázs AU - Hamvas, József AU - Bod, Barnabás AU - Varga, Márta AU - Török, Imola AU - Novák, János AU - Patai, Árpád AU - Sümegi, János AU - Góg, Csaba AU - Papp, Mária AU - Erőss, Bálint Mihály AU - Váncsa, Szilárd AU - Teutsch, Brigitta AU - Márta, Katalin AU - Hegyi, Péter Jenő AU - Tornai, Tamás AU - Lázár, Balázs AU - Hussein, Tamás AU - Tarján, Dorottya AU - Lipp, Mónika Bernadett AU - Kovács, Beáta AU - Urbán, Orsolya AU - Fürst, Emese Rita AU - Tari, Edina AU - Kocsis, Ibolya AU - Maurovich-Horvat, Pál AU - Tihanyi, Balázs AU - Eperjesi, Orsolya AU - Kormos, Zita AU - Deák, Pál Ákos AU - Párniczky, Andrea AU - Hegyi, Péter TI - Discharge protocol in acute pancreatitis: an international survey and cohort analysis JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 13 PY - 2023 IS - 1 PG - 10 SN - 2045-2322 DO - 10.1038/s41598-023-48480-z UR - https://m2.mtmt.hu/api/publication/34434496 ID - 34434496 AB - There are several overlapping clinical practice guidelines in acute pancreatitis (AP), however, none of them contains suggestions on patient discharge. The Hungarian Pancreatic Study Group (HPSG) has recently developed a laboratory data and symptom-based discharge protocol which needs to be validated. (1) A survey was conducted involving all members of the International Association of Pancreatology (IAP) to understand the characteristics of international discharge protocols. (2) We investigated the safety and effectiveness of the HPSG-discharge protocol. According to our international survey, 87.5% (49/56) of the centres had no discharge protocol. Patients discharged based on protocols have a significantly shorter median length of hospitalization (LOH) (7 (5;10) days vs. 8 (5;12) days) p < 0.001), and a lower rate of readmission due to recurrent AP episodes (p = 0.005). There was no difference in median discharge CRP level among the international cohorts (p = 0.586). HPSG-protocol resulted in the shortest LOH (6 (5;9) days) and highest median CRP (35.40 (13.78; 68.40) mg/l). Safety was confirmed by the low rate of readmittance (n = 35; 5%). Discharge protocol is necessary in AP. The discharge protocol used in this study is the first clinically proven protocol. Developing and testifying further protocols are needed to better standardize patients' care. LA - English DB - MTMT ER - TY - JOUR AU - Szabados, Márton AU - Kolumbán , Erika AU - Agócs, Gergely AU - Kiss-Dala, Szilvia AU - Engh, Marie Anne AU - Hernádfői , Márk Viktor AU - Takács, Kata AU - Tuboly, Eszter AU - Párniczky, Andrea AU - Hegyi, Péter AU - Garami, Miklós TI - Association of tumor location with anxiety and depression in childhood brain cancer survivors: a systematic review and meta-analysis JF - CHILD AND ADOLESCENT PSYCHIATRY AND MENTAL HEALTH J2 - CHILD ADOL PSYCH MEN VL - 17 PY - 2023 IS - 1 PG - 11 SN - 1753-2000 DO - 10.1186/s13034-023-00665-0 UR - https://m2.mtmt.hu/api/publication/34225351 ID - 34225351 N1 - Funding Agency and Grant Number: Semmelweis University Funding text: Open access funding provided by Semmelweis University. LA - English DB - MTMT ER - TY - JOUR AU - Martonosi, Ágnes Rita AU - Németh, Balázs Csaba AU - Párniczky, Andrea AU - Vincze, Áron AU - Szentesi, Andrea Ildikó AU - Erőss, Bálint Mihály AU - Sahin-Tóth, Miklós AU - Hegyi, Péter AU - Hegyi, Eszter TI - CFTR p.F508del Mutation Carrier Status Is Not Associated With Biliary Acute Pancreatitis JF - PANCREAS J2 - PANCREAS VL - 52 PY - 2023 IS - 4 SP - e256 EP - e257 SN - 0885-3177 DO - 10.1097/MPA.0000000000002241 UR - https://m2.mtmt.hu/api/publication/34196830 ID - 34196830 LA - English DB - MTMT ER - TY - GEN AU - Párniczky, Andrea TI - A CFTR modulátor terápia hatásai a tüdőn kívül PY - 2023 UR - https://m2.mtmt.hu/api/publication/34189050 ID - 34189050 N1 - {előadás} LA - Hungarian DB - MTMT ER - TY - JOUR AU - Juhász, Márk Félix AU - Tóháti, Rebeka AU - Jászai, Viktória Adrienn AU - Molnár, Regina AU - Borbásné Farkas, Kornélia AU - Czakó, László AU - Vincze, Áron AU - Erőss, Bálint Mihály AU - Szentesi, Andrea Ildikó AU - Izbéki, Ferenc AU - Papp, Mária AU - Hegyi, Péter AU - Párniczky, Andrea ED - Váncsa, Szilárd / Collaborator ED - Márta, Katalin / Collaborator ED - Földi, Mária / Collaborator ED - Nagy, Rita / Collaborator ED - Hegyi, Péter Jenő / Collaborator ED - Ocskay, Klementina / Collaborator ED - Imrei, Marcell / Collaborator ED - Mikó, Alexandra / Collaborator ED - Gódi, Szilárd / Collaborator ED - Bajor, Judit / Collaborator ED - Hágendorn, Roland / Collaborator ED - Sarlós, Patrícia / Collaborator ED - Szabó, Imre / Collaborator ED - Czimmer, József / Collaborator ED - Faluhelyi, Nándor / Collaborator ED - Kanizsai, Péter / Collaborator ED - Nagy, Tamás / Collaborator ED - Gajdán, László / Collaborator ED - Kui, Balázs / Collaborator ED - Illés, Dóra / Collaborator ED - Takács, Tamás / Collaborator ED - Vitális, Zsuzsanna / Collaborator ED - Hamvas, József / Collaborator ED - Varga, Márta / Collaborator ED - Bod, Barnabás / Collaborator ED - Novák, János / Collaborator ED - Maurovich-Horvat, Pál / Collaborator ED - Doros, Attila / Collaborator ED - Deák, Pál Ákos / Collaborator ED - Varga, Csaba / Collaborator ED - Gaál, Szabolcs / Collaborator ED - Zubek, László / Collaborator ED - Gál, János / Collaborator ED - Lázár, Balázs / Collaborator ED - Hussein, Tamás / Collaborator ED - Kovács, Bea / Collaborator ED - Tarján, Dorottya / Collaborator ED - Lipp, Mónika Bernadett / Collaborator ED - Urbán, Orsolya / Collaborator ED - Tornai, Tamás / Collaborator TI - Invalidity of Tokyo guidelines in acute biliary pancreatitis : A multicenter cohort analysis of 944 pancreatitis cases JF - UNITED EUROPEAN GASTROENTEROLOGY JOURNAL J2 - UEG JOURNAL VL - 11 PY - 2023 IS - 8 SP - 767 EP - 774 PG - 8 SN - 2050-6406 DO - 10.1002/ueg2.12402 UR - https://m2.mtmt.hu/api/publication/34072590 ID - 34072590 N1 - * Megosztott szerzőség AB - There is a noteworthy overlap between the clinical picture of biliary acute pancreatitis (AP) and the 2018 Tokyo guidelines currently used for the diagnosis of cholangitis (AC) and cholecystitis (CC). This can lead to significant antibiotic and endoscopic retrograde cholangiopancreatography (ERCP) overuse.We aimed to assess the on-admission prevalence of AC/CC according to the 2018 Tokyo guidelines (TG18) in a cohort of biliary AP patients, and its association with antibiotic use, ERCP and clinically relevant endpoints.We conducted a secondary analysis of the Hungarian Pancreatic Study Group's prospective multicenter registry of 2195 AP cases. We grouped and compared biliary cases (n = 944) based on the on-admission fulfillment of definite AC/CC according to TG18. Aside from antibiotic use, we evaluated mortality, AC/CC/AP severity, ERCP performance and length of hospitalization. We also conducted a literature review discussing each criteria of the TG18 in the context of AP.27.8% of biliary AP cases fulfilled TG18 for both AC and CC, 22.5% for CC only and 20.8% for AC only. Antibiotic use was high (77.4%). About 2/3 of the AC/CC cases were mild, around 10% severe. Mortality was below 1% in mild and moderate AC/CC patients, but considerably higher in severe cases (12.8% and 21.2% in AC and CC). ERCP was performed in 89.3% of AC cases, common bile duct stones were found in 41.1%.Around 70% of biliary AP patients fulfilled the TG18 for AC/CC, associated with a high rate of antibiotic use. Mortality in presumed mild or moderate AC/CC is low. Each of the laboratory and clinical criteria are commonly fulfilled in biliary AP, single imaging findings are also unspecific-AP specific diagnostic criteria are needed, as the prevalence of AC/CC are likely greatly overestimated. Randomized trials testing antibiotic use are also warranted. LA - English DB - MTMT ER - TY - CONF AU - Adrienn, F. Kéri AU - Dorina, Bajzát AU - Zita, Andrásdi AU - Márk, Félix Juhász AU - Rita, Nagy AU - Tamás, Kói AU - Nelli, Farkas AU - Kovács, Gábor AU - Péter, Hegyi AU - Párniczky, Andrea TI - A stitch in time saves nine – abnormal glucose tolerance in patients with cystic fibrosis: Systematic review and meta-analysis T2 - 31st Meeting of the European Society of Paediatric Clinical Research (ESPCR 2023) PY - 2023 SP - 20 EP - 20 PG - 1 UR - https://m2.mtmt.hu/api/publication/33871767 ID - 33871767 LA - English DB - MTMT ER -