@article{MTMT:34792056, title = {Burden of Childhood Cancer and the Social and Economic Challenges in Adulthood}, url = {https://m2.mtmt.hu/api/publication/34792056}, author = {Hernádfői , Márk Viktor and Koch, Dóra Kornélia and Kói, Tamás and Imrei, Marcell and Nagy, Rita and Máté, Vanda and Garai, Réka and Donnet, Jessica and Balogh, József and Kovács, Gábor and Párniczky, Andrea and Hegyi, Péter and Garami, Miklós}, doi = {10.1001/jamapediatrics.2024.0642}, journal-iso = {JAMA PEDIATR}, journal = {JAMA PEDIATRICS}, volume = {in}, unique-id = {34792056}, issn = {2168-6203}, year = {2024}, eissn = {2168-6211}, orcid-numbers = {Imrei, Marcell/0000-0003-0175-7462; Nagy, Rita/0000-0002-2663-4912; Máté, Vanda/0000-0003-1105-9692; Garai, Réka/0000-0001-6201-764X; Kovács, Gábor/0000-0001-9924-1645; Hegyi, Péter/0000-0003-0399-7259; Garami, Miklós/0000-0003-4298-2746} } @article{MTMT:34729555, title = {Early onset of abnormal glucose tolerance in patients with cystic fibrosis : A systematic review and meta-analysis}, url = {https://m2.mtmt.hu/api/publication/34729555}, author = {Ferencsikné Kéri, Adrienn Krisztina and Bajzát, Dorina Rita and Andrásdi, Zita and Juhász, Márk Félix and Nagy, Rita and Kói, Tamás and Kovács, Gábor and Hegyi, Péter and Párniczky, Andrea}, doi = {10.1016/j.jcf.2024.02.010}, journal-iso = {J CYST FIBROS}, journal = {JOURNAL OF CYSTIC FIBROSIS}, unique-id = {34729555}, issn = {1569-1993}, abstract = {Despite translational evidences suggesting that cystic fibrosis-related abnormal glucose tolerance (CF-related AGT) may begin early in life and is known to be associated with increased morbidity and mortality, current guidelines recommend screening for AGT only from 10 years of age, thus missing the opportunity for early detection and intervention.A systematic review and meta-analysis (PROSPERO number: CRD42021282516) was conducted on studies that reported data on the prevalence of AGT or its subtypes in CF populations. Pooled proportions, risk, and odds ratios with 95 % confidence intervals (CI) were calculated. One-stage dose-response random-effect meta-analysis was used to assess the effect of age on CF-related diabetes (CFRD).The quantitative analysis included 457 studies and data from 520,544 patients. Every third child with CF (chwCF) (0.31 [95 % CI 0.25-0.37]) and every second adult with CF (awCF) (0.51 [95 % CI 0.45-0.57]) were affected by AGT. Even in the 5-10 years of age subgroup, the proportion of AGT was 0.42 [95 % CI 0.34-0.51]. The prevalence of prediabetes remained unchanged (impaired glucose tolerance in chwCF:0.14 [95 % CI 0.10-0.18]) vs. awCF:0.19 [95 % CI 0.14-0.25]), whereas the proportion of CFRD increased with age (0-5: 0.005 [95 % CI 0.0001-0.15]; 5-10: 0.05 [95 % CI 0.01-0.27]; 10-18: 0.11 [95 % CI 0.08-0.14]; >18 years of age: 0.27 [95 % CI 0.24-0.30]).CF-related AGT is common under 10 years of age. Our study suggests considering earlier AGT screening, starting from 5 years of age. This highlights the imperative for additional research for guideline adjustments and provides the opportunity for early intervention.}, keywords = {PREVALENCE; EPIDEMIOLOGY; Meta-analysis; cystic fibrosis (CF); Glucose abnormalities; OGTT (Oral Glucose Tolerance Test)}, year = {2024}, eissn = {1873-5010}, orcid-numbers = {Nagy, Rita/0000-0002-2663-4912; Kovács, Gábor/0000-0001-9924-1645; Hegyi, Péter/0000-0003-0399-7259} } @{MTMT:34688862, title = {Krónikus pancreatitis}, url = {https://m2.mtmt.hu/api/publication/34688862}, author = {Párniczky, Andrea}, booktitle = {Klinikai gyermekgyógyászat}, unique-id = {34688862}, year = {2024}, pages = {631-632} } @article{MTMT:34498800, title = {Beyond the Gut: A Systematic Review and Meta-analysis of Advanced Therapies for Inflammatory Bowel Disease-associated Extraintestinal Manifestations}, url = {https://m2.mtmt.hu/api/publication/34498800}, author = {Tímár, Ágnes Eszter and Párniczky, Andrea and Budai, Kinga Anna and Hernádfői , Márk Viktor and Kasznár, Emese and Varga, Péter and Hegyi, Péter and Váncsa, Szilárd and Tóth, Réka and Veres, Dániel and Garami, Miklós and Müller, Katalin Eszter}, doi = {10.1093/ecco-jcc/jjae002}, journal-iso = {J CROHNS COLITIS}, journal = {JOURNAL OF CROHNS & COLITIS}, unique-id = {34498800}, issn = {1873-9946}, year = {2024}, eissn = {1876-4479}, orcid-numbers = {Hegyi, Péter/0000-0003-0399-7259; Váncsa, Szilárd/0000-0002-9347-8163; Veres, Dániel/0000-0002-9687-3556; Garami, Miklós/0000-0003-4298-2746; Müller, Katalin Eszter/0000-0001-5355-4224} } @article{MTMT:34434496, title = {Discharge protocol in acute pancreatitis: an international survey and cohort analysis}, url = {https://m2.mtmt.hu/api/publication/34434496}, author = {Nagy, Rita and Ocskay, Klementina and Sipos, Zoltán and Szentesi, Andrea Ildikó and Vincze, Áron and Czakó, László and Izbéki, Ferenc and Shirinskaya, Natalia V and Poluektov, Vladimir L and Zolotov, Alexandr N and Zhu, Yin and Xia, Liang and He, Wenhua and Sutton, Robert and Szatmary, Peter and Mukherjee, Rajarshi and Burridge, Isobel Saffron and Wauchope, Emma and Francisco, Elsa and Aparicio, David and Pinto, Bruno and Gomes, António and Nunes, Vitor and Tantau, Vasile Marcel and Sagau, Emanuela Denisa and Tantau, Alina Ioana and Suceveanu, Andra Iulia and Tocia, Cristina and Dumitru, Andrei and Pando, Elizabeth and Alberti, Piero and Cirera, Arturo and Molero, Xavier and Lee, Hong Sik and Jung, Min Kyu and Kim, Eui Joo and Lee, Sanghyub and Rebollo, María Lourdes Ruiz and Nistal, Reyes Busta and Santervas, Sandra Izquierdo and Lesko, Dusan and Soltes, Marek and Radonak, Jozef and Zatorski, Hubert and Małecka-Panas, Ewa and Fabisiak, Adam and Yaroslav, M Susak and Mykhailo, V Maksymenko and Olekcandr, A Tkachenko and Barauskas, Giedrius and Simanaitis, Vytautas and Ignatavicius, Povilas and Jinga, Mariana and Balaban, Vasile-Daniel and Patoni, Cristina and Gong, Liang and Song, Kai and Li, Yunlong and Gonçalves, T Cúrdia and Freitas, Marta and Macedo, Vítor and Vornhuelz, Marlies and Klauss, Sarah and Beyer, Georg and Koksal, Aydin Seref and Tozlu, Mukaddes and Eminler, Ahmet Tarik and Monclús, Nuria Torres and Comas, Eva Pijoan and Oballe, Juan Armando Rodriguez and Nawacki, Łukasz and Głuszek, Stanisław and Rama-Fernández, Alberto and Galego, Marco and de la Iglesia, Daniel and Aykut, Umut Emre and Duman, Deniz Güney and Aslan, Rahmi and Gherbon, Adriana and Deng, Lihui and Huang, Wei and Xia, Qing and Poropat, Goran and Radovan, Anja and Vranić, Luka and Ricci, Claudio and Ingaldi, Carlo and Casadei, Riccardo and Negoi, Ionut and Ciubotaru, Cezar and Iordache, Florin Mihail and Constantinescu, Gabriel and Sandru, Vasile and Altintas, Engin and Balci, Hatice Rizaoglu and Constantino, Júlio and Aveiro, Débora and Pereira, Jorge and Gunay, Suleyman and Misirlioglu Sucan, Seda and Dronov, Oleksiy and Kovalska, Inna and Bush, Nikhil and Rana, Surinder Singh and Chooklin, Serge and Chuklin, Serhii and Saizu, Ionut Adrian and Gheorghe, Cristian and Göltl, Philipp and Hirth, Michael and Mateescu, Radu Bogdan and Papuc, Geanina and Minkov, Georgi Angelov and Enchev, Emil Tihomirov and Mastrangelo, Laura and Jovine, Elio and Chen, Weiwei and Zhu, Quping and Gąsiorowska, Anita and Fabisiak, Natalia and Bezmarevic, Mihailo and Litvin, Andrey and Mottes, Martina Cattani and Choi, Eun Kwang and Bánovčin, Peter and Nosáková, Lenka and Kovacheva-Slavova, Mila Dimitrova and Kchaou, Ali and Tlili, Ahmed and Marino, Marco V and Kusnierz, Katarzyna and Mickevicius, Artautas and Hollenbach, Marcus and Molcan, Pavol and Ioannidis, Orestis and Tokarev, Mark Valerievich and Ince, Ali Tüzün and Semenenko, Ivan Albertovich and Galeev, Shamil and Ramírez-Maldonado, Elena and Sallinen, Ville and Pencik, Petr and Bajor, Judit and Sarlós, Patrícia and Hágendorn, Roland and Gódi, Szilárd and Szabó, Imre and Czimmer, József and Pár, Gabriella and Illés, Anita and Faluhelyi, Nándor and Kanizsai, Péter László and Nagy, Tamás and Mikó, Alexandra and Németh, Balázs and Hamvas, József and Bod, Barnabás and Varga, Márta and Török, Imola and Novák, János and Patai, Árpád and Sümegi, János and Góg, Csaba and Papp, Mária and Erőss, Bálint Mihály and Váncsa, Szilárd and Teutsch, Brigitta and Márta, Katalin and Hegyi, Péter Jenő and Tornai, Tamás and Lázár, Balázs and Hussein, Tamás and Tarján, Dorottya and Lipp, Mónika Bernadett and Kovács, Beáta and Urbán, Orsolya and Fürst, Emese Rita and Tari, Edina and Kocsis, Ibolya and Maurovich-Horvat, Pál and Tihanyi, Balázs and Eperjesi, Orsolya and Kormos, Zita and Deák, Pál Ákos and Párniczky, Andrea and Hegyi, Péter}, doi = {10.1038/s41598-023-48480-z}, journal-iso = {SCI REP}, journal = {SCIENTIFIC REPORTS}, volume = {13}, unique-id = {34434496}, issn = {2045-2322}, abstract = {There are several overlapping clinical practice guidelines in acute pancreatitis (AP), however, none of them contains suggestions on patient discharge. The Hungarian Pancreatic Study Group (HPSG) has recently developed a laboratory data and symptom-based discharge protocol which needs to be validated. (1) A survey was conducted involving all members of the International Association of Pancreatology (IAP) to understand the characteristics of international discharge protocols. (2) We investigated the safety and effectiveness of the HPSG-discharge protocol. According to our international survey, 87.5% (49/56) of the centres had no discharge protocol. Patients discharged based on protocols have a significantly shorter median length of hospitalization (LOH) (7 (5;10) days vs. 8 (5;12) days) p < 0.001), and a lower rate of readmission due to recurrent AP episodes (p = 0.005). There was no difference in median discharge CRP level among the international cohorts (p = 0.586). HPSG-protocol resulted in the shortest LOH (6 (5;9) days) and highest median CRP (35.40 (13.78; 68.40) mg/l). Safety was confirmed by the low rate of readmittance (n = 35; 5%). Discharge protocol is necessary in AP. The discharge protocol used in this study is the first clinically proven protocol. Developing and testifying further protocols are needed to better standardize patients' care.}, year = {2023}, eissn = {2045-2322}, orcid-numbers = {Nagy, Rita/0000-0002-2663-4912; Ocskay, Klementina/0000-0001-5848-2506; Sipos, Zoltán/0000-0001-7845-8116; Szentesi, Andrea Ildikó/0000-0003-2097-6927; Vincze, Áron/0000-0003-2217-7686; Czakó, László/0000-0002-6331-0802; Izbéki, Ferenc/0000-0001-7767-4319; Sarlós, Patrícia/0000-0002-5086-9455; Czimmer, József/0000-0001-7831-3523; Kanizsai, Péter László/0000-0001-7896-2857; Nagy, Tamás/0000-0001-5437-1411; Németh, Balázs/0000-0001-5338-7577; Papp, Mária/0000-0003-3662-4010; Erőss, Bálint Mihály/0000-0003-3658-8427; Váncsa, Szilárd/0000-0002-9347-8163; Teutsch, Brigitta/0000-0002-9530-7886; Márta, Katalin/0000-0002-2213-4865; Tari, Edina/0000-0002-8540-0614; Kocsis, Ibolya/0000-0003-3128-2832; Maurovich-Horvat, Pál/0000-0003-0885-736X; Hegyi, Péter/0000-0003-0399-7259} } @article{MTMT:34225351, title = {Association of tumor location with anxiety and depression in childhood brain cancer survivors: a systematic review and meta-analysis}, url = {https://m2.mtmt.hu/api/publication/34225351}, author = {Szabados, Márton and Kolumbán , Erika and Agócs, Gergely and Kiss-Dala, Szilvia and Engh, Marie Anne and Hernádfői , Márk Viktor and Takács, Kata and Tuboly, Eszter and Párniczky, Andrea and Hegyi, Péter and Garami, Miklós}, doi = {10.1186/s13034-023-00665-0}, journal-iso = {CHILD ADOL PSYCH MEN}, journal = {CHILD AND ADOLESCENT PSYCHIATRY AND MENTAL HEALTH}, volume = {17}, unique-id = {34225351}, year = {2023}, eissn = {1753-2000}, orcid-numbers = {Agócs, Gergely/0000-0003-2489-3790; Engh, Marie Anne/0000-0003-4269-5130; Hegyi, Péter/0000-0003-0399-7259; Garami, Miklós/0000-0003-4298-2746} } @article{MTMT:34196830, title = {CFTR p.F508del Mutation Carrier Status Is Not Associated With Biliary Acute Pancreatitis}, url = {https://m2.mtmt.hu/api/publication/34196830}, author = {Martonosi, Ágnes Rita and Németh, Balázs Csaba and Párniczky, Andrea and Vincze, Áron and Szentesi, Andrea Ildikó and Erőss, Bálint Mihály and Sahin-Tóth, Miklós and Hegyi, Péter and Hegyi, Eszter}, doi = {10.1097/MPA.0000000000002241}, journal-iso = {PANCREAS}, journal = {PANCREAS}, volume = {52}, unique-id = {34196830}, issn = {0885-3177}, year = {2023}, eissn = {1536-4828}, pages = {e256-e257}, orcid-numbers = {Martonosi, Ágnes Rita/0000-0001-6528-4671; Vincze, Áron/0000-0003-2217-7686; Szentesi, Andrea Ildikó/0000-0003-2097-6927; Erőss, Bálint Mihály/0000-0003-3658-8427; Hegyi, Péter/0000-0003-0399-7259} } @misc{MTMT:34189050, title = {A CFTR modulátor terápia hatásai a tüdőn kívül}, url = {https://m2.mtmt.hu/api/publication/34189050}, author = {Párniczky, Andrea}, unique-id = {34189050}, year = {2023} } @article{MTMT:34072590, title = {Invalidity of Tokyo guidelines in acute biliary pancreatitis : A multicenter cohort analysis of 944 pancreatitis cases}, url = {https://m2.mtmt.hu/api/publication/34072590}, author = {Juhász, Márk Félix and Tóháti, Rebeka and Jászai, Viktória Adrienn and Molnár, Regina and Borbásné Farkas, Kornélia and Czakó, László and Vincze, Áron and Erőss, Bálint Mihály and Szentesi, Andrea Ildikó and Izbéki, Ferenc and Papp, Mária and Hegyi, Péter and Párniczky, Andrea}, doi = {10.1002/ueg2.12402}, journal-iso = {UEG JOURNAL}, journal = {UNITED EUROPEAN GASTROENTEROLOGY JOURNAL}, volume = {11}, unique-id = {34072590}, issn = {2050-6406}, abstract = {There is a noteworthy overlap between the clinical picture of biliary acute pancreatitis (AP) and the 2018 Tokyo guidelines currently used for the diagnosis of cholangitis (AC) and cholecystitis (CC). This can lead to significant antibiotic and endoscopic retrograde cholangiopancreatography (ERCP) overuse.We aimed to assess the on-admission prevalence of AC/CC according to the 2018 Tokyo guidelines (TG18) in a cohort of biliary AP patients, and its association with antibiotic use, ERCP and clinically relevant endpoints.We conducted a secondary analysis of the Hungarian Pancreatic Study Group's prospective multicenter registry of 2195 AP cases. We grouped and compared biliary cases (n = 944) based on the on-admission fulfillment of definite AC/CC according to TG18. Aside from antibiotic use, we evaluated mortality, AC/CC/AP severity, ERCP performance and length of hospitalization. We also conducted a literature review discussing each criteria of the TG18 in the context of AP.27.8% of biliary AP cases fulfilled TG18 for both AC and CC, 22.5% for CC only and 20.8% for AC only. Antibiotic use was high (77.4%). About 2/3 of the AC/CC cases were mild, around 10% severe. Mortality was below 1% in mild and moderate AC/CC patients, but considerably higher in severe cases (12.8% and 21.2% in AC and CC). ERCP was performed in 89.3% of AC cases, common bile duct stones were found in 41.1%.Around 70% of biliary AP patients fulfilled the TG18 for AC/CC, associated with a high rate of antibiotic use. Mortality in presumed mild or moderate AC/CC is low. Each of the laboratory and clinical criteria are commonly fulfilled in biliary AP, single imaging findings are also unspecific-AP specific diagnostic criteria are needed, as the prevalence of AC/CC are likely greatly overestimated. Randomized trials testing antibiotic use are also warranted.}, keywords = {MORTALITY; Antibiotic use; cholangitis; endoscopic retrograde cholangiopancreatography; cholecystitis; ERCP; STONES; Biliary acute pancreatitis; 2018 Tokyo guidelines}, year = {2023}, eissn = {2050-6414}, pages = {767-774}, orcid-numbers = {Molnár, Regina/0009-0009-7067-1647; Borbásné Farkas, Kornélia/0000-0002-5349-6527; Czakó, László/0000-0002-6331-0802; Vincze, Áron/0000-0003-2217-7686; Erőss, Bálint Mihály/0000-0003-3658-8427; Szentesi, Andrea Ildikó/0000-0003-2097-6927; Izbéki, Ferenc/0000-0001-7767-4319; Papp, Mária/0000-0003-3662-4010; Hegyi, Péter/0000-0003-0399-7259; Váncsa, Szilárd/0000-0002-9347-8163; Márta, Katalin/0000-0002-2213-4865; Nagy, Rita/0000-0002-2663-4912; Imrei, Marcell/0000-0003-0175-7462; Maurovich-Horvat, Pál/0000-0003-0885-736X; Doros, Attila/0000-0002-6496-9895; Zubek, László/0000-0003-0583-3290; Gál, János/0000-0001-9160-6478} } @CONFERENCE{MTMT:33871767, title = {A stitch in time saves nine – abnormal glucose tolerance in patients with cystic fibrosis: Systematic review and meta-analysis}, url = {https://m2.mtmt.hu/api/publication/33871767}, author = {Adrienn, F. Kéri and Dorina, Bajzát and Zita, Andrásdi and Márk, Félix Juhász and Rita, Nagy and Tamás, Kói and Nelli, Farkas and Kovács, Gábor and Péter, Hegyi and Párniczky, Andrea}, booktitle = {31st Meeting of the European Society of Paediatric Clinical Research (ESPCR 2023)}, unique-id = {33871767}, year = {2023}, pages = {20-20}, orcid-numbers = {Kovács, Gábor/0000-0001-9924-1645} }