@article{MTMT:33555087,
	title = {A Novel Method for Primary Blood Cell Culturing and Selection in Drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/33555087},
	author = {Kúthy-Sutus, Enikő and Kharrat, Bayan and Gábor, Erika and Csordás, Gábor and Sinka, Rita and Honti, Viktor},
	doi = {10.3390/cells12010024},
	journal-iso = {CELLS-BASEL},
	journal = {CELLS},
	volume = {12},
	unique-id = {33555087},
	abstract = {The blood cells of the fruit fly Drosophila melanogaster show many similarities to their vertebrate counterparts, both in their functions and their differentiation. In the past decades, a wide palette of immunological and transgenic tools and methods have been developed to study hematopoiesis in the Drosophila larva. However, the in vivo observation of blood cells is technically restricted by the limited transparency of the body and the difficulty in keeping the organism alive during imaging. Here we describe an improved ex vivo culturing method that allows effective visualization and selection of live blood cells in primary cultures derived from Drosophila larvae. Our results show that cultured hemocytes accurately represent morphological and functional changes following immune challenges and in case of genetic alterations. Since cell culturing has hugely contributed to the understanding of the physiological properties of vertebrate blood cells, this method provides a versatile tool for studying Drosophila hemocyte differentiation and functions ex vivo.},
	year = {2023},
	eissn = {2073-4409},
	orcid-numbers = {Kúthy-Sutus, Enikő/0000-0002-1398-4120; Csordás, Gábor/0000-0001-6871-6839; Sinka, Rita/0000-0003-4040-4184}
}

@CONFERENCE{MTMT:34689202,
	title = {Studying Drosophila blood cell plasticity using primary blood cell cultures},
	url = {https://m2.mtmt.hu/api/publication/34689202},
	author = {Kúthy-Sutus, Enikő and Gábor, Erika and Kharrat, Bayan and Jankovics, Ferenc and Sinka, Rita and Honti, Viktor},
	booktitle = {Straub-Napok 2022},
	unique-id = {34689202},
	year = {2022},
	pages = {1},
	orcid-numbers = {Kúthy-Sutus, Enikő/0000-0002-1398-4120; Sinka, Rita/0000-0003-4040-4184}
}

@article{MTMT:33050458,
	title = {Peeling Back the Layers of Lymph Gland Structure and Regulation},
	url = {https://m2.mtmt.hu/api/publication/33050458},
	author = {Kharrat, Bayan and Csordás, Gábor and Honti, Viktor},
	doi = {10.3390/ijms23147767},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {23},
	unique-id = {33050458},
	issn = {1661-6596},
	abstract = {During the past 60 years, the fruit fly, Drosophila melanogaster, has proven to be an excellent model to study the regulation of hematopoiesis. This is not only due to the evolutionarily conserved signalling pathways and transcription factors contributing to blood cell fate, but also to convergent evolution that led to functional similarities in distinct species. An example of convergence is the compartmentalization of blood cells, which ensures the quiescence of hematopoietic stem cells and allows for the rapid reaction of the immune system upon challenges. The lymph gland, a widely studied hematopoietic organ of the Drosophila larva, represents a microenvironment with similar features and functions to classical hematopoietic stem cell niches of vertebrates. Lymph gland studies were effectively supported by the unparalleled toolkit developed in Drosophila, which enabled the high-resolution investigation of the cellular composition and regulatory interaction networks of the lymph gland. In this review, we summarize how our understanding of lymph gland structure and hematopoietic cell-to-cell communication evolved during the past decades and compare their analogous features to those of the vertebrate hematopoietic stem cell niche.},
	keywords = {IMMUNE-RESPONSE; DROSOPHILA; matrix protein; Hematopoiesis; SELF-RENEWAL; HEMATOPOIETIC STEM-CELL; Biochemistry & Molecular Biology; HSC; N-cadherin; lymph gland; EMBRYONIC ORIGIN; Drosophila larvae; PROGENITOR MAINTENANCE; HEMOCYTE LINEAGES},
	year = {2022},
	eissn = {1422-0067},
	orcid-numbers = {Csordás, Gábor/0000-0001-6871-6839}
}

@article{MTMT:32023128,
	title = {Regression plane concept for analysing continuous cellular processes with machine learning},
	url = {https://m2.mtmt.hu/api/publication/32023128},
	author = {Szkalisity, Ábel and Piccinini, Filippo and Beleon, Attila and Balassa, Tamás and Varga, Gergely István and Migh, Ede and Molnár, Csaba and Paavolainen, Lassi and Timonen, Sanna and Banerjee, Indranil and Ikonen, Elina and Yamauchi, Yohei and Andó, István and Peltonen, Jaakko and Pietiäinen, Vilja and Honti, Viktor and Horváth, Péter},
	doi = {10.1038/s41467-021-22866-x},
	journal-iso = {NAT COMMUN},
	journal = {NATURE COMMUNICATIONS},
	volume = {12},
	unique-id = {32023128},
	issn = {2041-1723},
	year = {2021},
	eissn = {2041-1723},
	orcid-numbers = {Piccinini, Filippo/0000-0002-0371-7782; Varga, Gergely István/0000-0001-9073-5788; Molnár, Csaba/0000-0002-6124-1209; Ikonen, Elina/0000-0001-8382-1135; Yamauchi, Yohei/0000-0002-8233-9133; Andó, István/0000-0002-4648-9396; Pietiäinen, Vilja/0000-0003-3125-2406}
}

@article{MTMT:31940120,
	title = {Immunoprofiling of Drosophila Hemocytes by Single-cell Mass Cytometry},
	url = {https://m2.mtmt.hu/api/publication/31940120},
	author = {Balog, József Ágoston and Honti, Viktor and Kurucz, Judit Éva and Kari, Beáta and Puskás, László and Andó, István and Szebeni, Gábor},
	doi = {10.1016/j.gpb.2020.06.022},
	journal-iso = {GENOM PROTEOM BIOINF},
	journal = {GENOMICS PROTEOMICS & BIOINFORMATICS},
	volume = {19},
	unique-id = {31940120},
	issn = {1672-0229},
	year = {2021},
	eissn = {2210-3244},
	pages = {243-252},
	orcid-numbers = {Andó, István/0000-0002-4648-9396; Szebeni, Gábor/0000-0002-6998-5632}
}

@article{MTMT:31743832,
	title = {There and back again: The mechanisms of differentiation and transdifferentiation in Drosophila blood cells},
	url = {https://m2.mtmt.hu/api/publication/31743832},
	author = {Csordás, Gábor and Gábor, Erika and Honti, Viktor},
	doi = {10.1016/j.ydbio.2020.10.006},
	journal-iso = {DEV BIOL},
	journal = {DEVELOPMENTAL BIOLOGY},
	volume = {469},
	unique-id = {31743832},
	issn = {0012-1606},
	year = {2021},
	eissn = {1095-564X},
	pages = {135-143},
	orcid-numbers = {Csordás, Gábor/0000-0001-6871-6839}
}

@article{MTMT:31891672,
	title = {Function and Interacting Partners of Headcase in Drosophila Melanogaster},
	url = {https://m2.mtmt.hu/api/publication/31891672},
	author = {Kharrat, B and Gábor, Erika and Sinka, Rita and Honti, Viktor},
	journal-iso = {IMMUNOLÓGIAI SZEMLE},
	journal = {IMMUNOLÓGIAI SZEMLE},
	volume = {12},
	unique-id = {31891672},
	issn = {2061-0203},
	year = {2020},
	pages = {25-25},
	orcid-numbers = {Sinka, Rita/0000-0003-4040-4184}
}

@article{MTMT:31891648,
	title = {Vérsejtek transzdifferenciálódásának vizsgálata a mélytanulás módszerével Drosophila melanogasterben},
	url = {https://m2.mtmt.hu/api/publication/31891648},
	author = {Gábor, Erika and Varga, GI and Géczi, Aliz and Bayan, K and Migh, E and Beleon, A and Horvath, P and Szeplaki, B and Enyedi, M and Pinter, L and Haracska, L and Honti, Viktor},
	journal-iso = {IMMUNOLÓGIAI SZEMLE},
	journal = {IMMUNOLÓGIAI SZEMLE},
	volume = {12},
	unique-id = {31891648},
	issn = {2061-0203},
	year = {2020},
	pages = {8-9}
}

@article{MTMT:31302837,
	title = {Identification of reference markers for characterizing honey bee (Apis mellifera) hemocyte classes},
	url = {https://m2.mtmt.hu/api/publication/31302837},
	author = {Gábor, Erika and Cinege, Gyöngyi Ilona and Csordás, Gábor and Rusvai, Miklós and Honti, Viktor and Kolics, Balázs and Török, Tibor and Williams, Michael J and Kurucz, Judit Éva and Andó, István},
	doi = {10.1016/j.dci.2020.103701},
	journal-iso = {DEV COMP IMMUNOL},
	journal = {DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY},
	volume = {109},
	unique-id = {31302837},
	issn = {0145-305X},
	abstract = {Cell mediated immunity of the honey bee (Apis mellifera) involves the activity of several hemocyte populations, currently defined by morphological features and lectin binding characteristics. The objective of the present study was to identify molecular markers capable of characterizing subsets of honey bee hemocytes. We developed and employed monoclonal antibodies with restricted reactions to functionally distinct hemocyte subpopulations. Melanizing cells, known as oenocytoids, were defined by an antibody to prophenoloxidase, aggregating cells were identified by the expression of Hemolectin, and phagocytic cells were identified by a marker expressed on granulocytes. We anticipate that this combination of antibodies not only allows for the detection of functionally distinct hemocyte subtypes, but will help to further the exploration of hematopoietic compartments, as well as reveal details of the honey bee cellular immune defense against parasites and microbes.},
	keywords = {Immunity; monoclonal antibody; Hemocyte; Apis mellifera; Honey bee; insect immunity},
	year = {2020},
	eissn = {1879-0089},
	pages = {103701-103706},
	orcid-numbers = {Csordás, Gábor/0000-0001-6871-6839; Török, Tibor/0000-0002-2128-1126; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:30864553,
	title = {Headcase Regulates Hemocyte Differentiation in Drosophila Melanogaster},
	url = {https://m2.mtmt.hu/api/publication/30864553},
	author = {Varga, GI and Csordas, G and Jankovics, F and Cinege, Gyöngyi Ilona and Sinka, Rita and Kurucz, E and Andó, István and Honti, Viktor},
	journal-iso = {IMMUNOLÓGIAI SZEMLE},
	journal = {IMMUNOLÓGIAI SZEMLE},
	volume = {11},
	unique-id = {30864553},
	issn = {2061-0203},
	year = {2019},
	pages = {20-21},
	orcid-numbers = {Sinka, Rita/0000-0003-4040-4184; Andó, István/0000-0002-4648-9396}
}