@article{MTMT:34227657,
	title = {One third of cases of new-onset diabetic ketosis in adults are associated with ketosis-prone type 2 diabetes-A systematic review and meta-analysis},
	url = {https://m2.mtmt.hu/api/publication/34227657},
	author = {Kovács, Adrienn Nikolett and Bunduc, Stefania and Veres, Dániel and Pálinkás, Dániel and Gagyi , Endre and Hegyi, Péter Jenő and Erőss, Bálint Mihály and Mihály, Emese and Hegyi, Péter and Hosszúfalusi, Nóra},
	doi = {10.1002/dmrr.3743},
	journal-iso = {DIABETES-METAB RES},
	journal = {DIABETES-METABOLISM RESEARCH AND REVIEWS},
	volume = {40},
	unique-id = {34227657},
	issn = {1520-7552},
	abstract = {Ketosis-prone type 2 diabetes was defined by the World Health Organization in 2019. According to the literature, the diagnosis is based on the presence of ketosis, islet autoantibody negativity and preserved insulin secretion. Our meta-analysis assessed the prevalence and clinical characteristics of ketosis-prone type 2 diabetes among patients hospitalised with diabetic ketoacidosis (DKA) or ketosis.The systematic search was performed in five main databases as of 15 October 2021 without restrictions. We calculated the pooled prevalence of ketosis-prone type 2 diabetes (exposed group) within the diabetic population under examination, patients with ketoacidosis or ketosis, to identify the clinical characteristics, and we compared it to type 1 diabetes (the comparator group). The random effects model provided pooled estimates as prevalence, odds ratio and mean difference (MD) with 95% confidence intervals.Eleven articles were eligible for meta-analysis, thus incorporating 2010 patients of various ethnic backgrounds. Among patients presenting with DKA or ketosis at the onset of diabetes, 35% (95% CI: 24%-49%) had ketosis-prone type 2 diabetes. These patients were older (MD = 11.55 years; 95% CI: 5.5-17.6) and had a significantly higher body mass index (BMI) (MD = 5.48 kg/m2 ; 95% CI: 3.25-7.72) than those with type 1 diabetes.Ketosis-prone type 2 diabetes accounts for one third of DKA or ketosis at the onset of diabetes in adults. These patients are characterised by islet autoantibody negativity and preserved insulin secretion. They are older and have a higher BMI compared with type 1 diabetes. C-peptide and diabetes-related autoantibody measurement is essential to identify this subgroup among patients with ketosis at the onset of diabetes.},
	keywords = {Meta-analysis; diabetic ketoacidosis; diabetes classification; ketosis-prone type 2; [Meta-analysis]},
	year = {2024},
	eissn = {1520-7560},
	orcid-numbers = {Veres, Dániel/0000-0002-9687-3556; Erőss, Bálint Mihály/0000-0003-3658-8427; Mihály, Emese/0000-0003-3046-7341; Hegyi, Péter/0000-0003-0399-7259; Hosszúfalusi, Nóra/0000-0002-9469-372X}
}

@article{MTMT:34565192,
	title = {A DIABETESHEZ KAPCSOLT AUTOANTITEST ÉS A C-PEPTID MEGHATÁROZÁS JELENTŐSÉGE FELNŐTTKORBAN, KETÓZISSAL INDULÓ CUKORBETEGSÉGBEN: PROSPEKTÍV VIZSGÁLAT},
	url = {https://m2.mtmt.hu/api/publication/34565192},
	author = {Kovács, A and Hosszúfalusi, Nóra and Lukács, Krisztina and Sipter, Emese and Teutsch, Brigitta and Veres, Dániel and Hegyi, Péter and Pánczél, Pál},
	journal-iso = {MBA},
	journal = {MAGYAR BELORVOSI ARCHIVUM},
	volume = {76},
	unique-id = {34565192},
	issn = {0133-5464},
	year = {2023},
	pages = {318-319},
	orcid-numbers = {Hosszúfalusi, Nóra/0000-0002-9469-372X; Lukács, Krisztina/0000-0002-4004-066X; Sipter, Emese/0000-0002-3730-3270; Teutsch, Brigitta/0000-0002-9530-7886; Hegyi, Péter/0000-0003-0399-7259; Pánczél, Pál/0000-0001-5337-9489}
}

@article{MTMT:34536097,
	title = {Risk factors for diabetes mellitus after acute pancreatitis : a systematic review and meta-analysis},
	url = {https://m2.mtmt.hu/api/publication/34536097},
	author = {Zahariev, Julia Olga and Bunduc, Stefania and Kovács, Adrienn Nikolett and Demeter, Dóra and Havelda, Luca and Budai, Bettina Csilla and Veres, Dániel and Hosszúfalusi, Nóra and Erőss, Bálint Mihály and Teutsch, Brigitta and Juhász, Márk Félix and Hegyi, Péter},
	doi = {10.3389/fmed.2023.1257222},
	journal-iso = {FRONT MED},
	journal = {FRONTIERS IN MEDICINE},
	volume = {10},
	unique-id = {34536097},
	abstract = {Within 5 years of having acute pancreatitis (AP), approximately 20% of patients develop diabetes mellitus (DM), which later increases to approximately 40%. Some studies suggest that the prevalence of prediabetes (PD) and/or DM can grow as high as 59% over time. However, information on risk factors is limited. We aimed to identify risk factors for developing PD or DM following AP.We systematically searched three databases up to 4 September 2023 extracting direct, within-study comparisons of risk factors on the rate of new-onset PD and DM in AP patients. When PD and DM event rates could not be separated, we reported results for this composite outcome as PD/DM. Meta-analysis was performed using the random-effects model to calculate pooled odds ratios (OR) with 95% confidence intervals (CI).Of the 61 studies identified, 50 were included in the meta-analysis, covering 76,797 participants. The studies reported on 79 risk factors, and meta-analysis was feasible for 34 risk factor and outcome pairs. The odds of developing PD/DM was significantly higher after severe and moderately severe AP (OR: 4.32; CI: 1.76-10.60) than mild AP. Hypertriglyceridemic AP etiology (OR: 3.27; CI: 0.17-63.91) and pancreatic necrosis (OR: 5.53; CI: 1.59-19.21) were associated with a higher risk of developing PD/DM. Alcoholic AP etiology (OR: 1.82; CI: 1.09-3.04), organ failure (OR: 3.19; CI: 0.55-18.64), recurrent AP (OR: 1.89; CI: 0.95-3.77), obesity (OR: 1.85; CI: 1.43-2.38), chronic kidney disease (OR: 2.10; CI: 1.85-2.38), liver cirrhosis (OR: 2.48; CI: 0.18-34.25), and dyslipidemia (OR: 1.82; CI: 0.68-4.84) were associated with a higher risk of developing DM.Severe and moderately severe AP, alcoholic and hypertriglyceridemic etiologies, pancreatic necrosis, organ failure, recurrent acute pancreatitis and comorbidities of obesity, chronic kidney disease liver disease, and dyslipidemia are associated with a higher risk of developing PD or DM.https://www.crd.york.ac.uk/prospero/, identifier CRD42021281983.},
	keywords = {diabetes mellitus; prediabetes; gastrointestinal disorders; acute pancreatitis (AP); risk factor (RF); pancreatitis—complications; [Meta-analysis]},
	year = {2023},
	eissn = {2296-858X},
	orcid-numbers = {Veres, Dániel/0000-0002-9687-3556; Hosszúfalusi, Nóra/0000-0002-9469-372X; Erőss, Bálint Mihály/0000-0003-3658-8427; Teutsch, Brigitta/0000-0002-9530-7886; Hegyi, Péter/0000-0003-0399-7259}
}

@article{MTMT:34103678,
	title = {One in four patients with gastrointestinal bleeding develops shock or hemodynamic instability : A systematic review and meta-analysis},
	url = {https://m2.mtmt.hu/api/publication/34103678},
	author = {Obeidat, Mahmoud Mohammadnour Suleiman and Teutsch, Brigitta and Rancz, Anett and Tari, Edina and Márta, Katalin and Veres, Dániel and Hosszúfalusi, Nóra and Mihály, Emese and Hegyi, Péter and Erőss, Bálint Mihály},
	doi = {10.3748/wjg.v29.i28.4466},
	journal-iso = {WORLD J LGASTROENTEROL},
	journal = {WORLD JOURNAL OF GASTROENTEROLOGY},
	volume = {29},
	unique-id = {34103678},
	issn = {1007-9327},
	abstract = {Hemodynamic instability and shock are associated with untoward outcomes in gastrointestinal bleeding. However, there are no studies in the existing literature on the proportion of patients who developed these outcomes after gastrointestinal bleeding.To determine the pooled event rates in the available literature and specify them based on the bleeding source.The protocol was registered on PROSPERO in advance (CRD42021283258). A systematic search was performed in three databases (PubMed, EMBASE, and CENTRAL) on 14th October 2021. Pooled proportions with 95%CI were calculated with a random-effects model. A subgroup analysis was carried out based on the time of assessment (on admission or during hospital stay). Heterogeneity was assessed by Higgins and Thompson's I2 statistics. The Joanna Briggs Institute Prevalence Critical Appraisal Tool was used for the risk of bias assessment. The Reference Citation Analysis (https://www.referencecitationanalysis.com/) tool was applied to obtain the latest highlight articles.We identified 11589 records, of which 220 studies were eligible for data extraction. The overall proportion of shock and hemodynamic instability in general gastrointestinal bleeding patients was 0.25 (95%CI: 0.17-0.36, I2 = 100%). In non-variceal bleeding, the proportion was 0.22 (95%CI: 0.14-0.31, I2 = 100%), whereas it was 0.25 (95%CI: 0.19-0.32, I2 = 100%) in variceal bleeding. The proportion of patients with colonic diverticular bleeding who developed shock or hemodynamic instability was 0.12 (95%CI: 0.06-0.22, I2 = 90%). The risk of bias was low, and heterogeneity was high in all analyses.One in five, one in four, and one in eight patients develops shock or hemodynamic instability on admission or during hospitalization in the case of non-variceal, variceal, and colonic diverticular bleeding, respectively.},
	keywords = {review; statistics; Meta-analysis; shock; Gastrointestinal bleeding; Hemodynamic instability; [Meta-analysis]},
	year = {2023},
	eissn = {2219-2840},
	pages = {4466-4480},
	orcid-numbers = {Teutsch, Brigitta/0000-0002-9530-7886; Tari, Edina/0000-0002-8540-0614; Márta, Katalin/0000-0002-2213-4865; Veres, Dániel/0000-0002-9687-3556; Hosszúfalusi, Nóra/0000-0002-9469-372X; Mihály, Emese/0000-0003-3046-7341; Hegyi, Péter/0000-0003-0399-7259; Erőss, Bálint Mihály/0000-0003-3658-8427}
}

@article{MTMT:34039131,
	title = {Microscopic colitis is a risk factor for low bone density: a systematic review and meta-analysis},
	url = {https://m2.mtmt.hu/api/publication/34039131},
	author = {Rancz, Anett and Teutsch, Brigitta and Engh, Marie Anne and Veres, Dániel and Földvári-Nagy, László and Erőss, Bálint Mihály and Hosszúfalusi, Nóra and Juhász, Márk Félix and Hegyi, Péter and Mihály, Emese},
	doi = {10.1177/17562848231177151},
	journal-iso = {THER ADV GASTROENTER},
	journal = {THERAPEUTIC ADVANCES IN GASTROENTEROLOGY},
	volume = {16},
	unique-id = {34039131},
	issn = {1756-283X},
	abstract = {Background:Microscopic colitis (MC) is a chronic inflammatory disease of the large bowel characterized by watery diarrhea, substantially decreasing the patient's quality of life. Scarce data suggest that MC is associated with low bone density (LBD). Objectives:We aimed to assess whether MC is a risk factor for LBD and the proportion of patients with MC having LBD. Design:A systematic review and meta-analysis of studies reporting bone density measurements in MC patients. Data Sources and Methods:We systematically searched five databases from inception to October 16, 2021 (Pubmed, Embase, Cochrane, Scopus, and Web of Science). We used the random-effect model to calculate pooled odds ratios (ORs) and pooled event rates with 95% confidence intervals (CIs). To ascertain the quality of evidence of our outcomes, we followed the recommendations of the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) Working Group. Results:The systematic search yielded a total of 3046 articles. Four articles were eligible for quantitative synthesis. All of them used age- and sex-matched controls to evaluate LBD occurrence among patients with MC. The odds of having LBD were twofold increased (OR = 2.13, CI: 1.42-3.20) in the presence of MC, the odds of osteopenia occurrence were 2.4 (OR = 2.45, CI: 1.11-5.41), and of osteoporosis 1.4 (OR = 1.42, CI: 0.65-3.12). The proportion of LBD was 0.68 (CI: 0.56-0.78), osteopenia was 0.51 (CI: 0.43-0.58), and osteoporosis was 0.11 (CI: 0.07-0.16) among the MC population. Our findings' certainty of the evidence was very low following the GRADEPro guideline. Conclusion:Our data demonstrate that MC is associated with a twofold risk for LBD. Based on our findings, we suggest screening patients for bone mineral density upon diagnosis of MC. Further prospective studies with higher patient numbers and longer follow-up periods on this topic are needed. Registration:Our protocol was prospectively registered with PROSPERO (CRD42021283392). Plain language summaryInvestigating microscopic colitis as a risk factor for having low bone density in a literature overview and statistical approachMicroscopic colitis (MC) is an underdiagnosed chronic inflammatory large bowel disease, characterized by watery diarrhea, which substantially impacts the patient's quality of life. The etiology of MC is still unclear but is suspected to be multifactorial. Moreover, low bone density (LBD) has been associated with the disease. Scarce data investigate the relationship of MC with LBD, although they share common risk factors, like advanced age and female sex. LBD has two forms; the mild is osteopenia and the severe form is osteoporosis. The most severe complications of osteoporosis are osteoporotic fractures, which can culminate in a life-threatening state and amplify the hospital expenses burden.Our primary aim was to assess if MC increases the risk of LBD. Furthermore, we estimated the proportions of bone mineral changes in the MC population.Following a rigorous methodology, our data suggest that MC doubles the odds of LBD. Furthermore, we have shown that two-thirds of the MC population suffers from bone density decrease, half of them have osteopenia, and one in 10 MC patients has osteoporosis.In conclusion, we highly suggest screening patients with MC for bone mineral density at the moment of diagnosis.},
	keywords = {CHILDREN; PATHOPHYSIOLOGY; Adolescents; osteoporosis; chronic inflammation; osteopenia; collagenous colitis; MINERAL DENSITY; Meta-regression; microscopic colitis; Low bone density; large bowel disease; [Meta-analysis]},
	year = {2023},
	eissn = {1756-2848},
	orcid-numbers = {Teutsch, Brigitta/0000-0002-9530-7886; Engh, Marie Anne/0000-0003-4269-5130; Veres, Dániel/0000-0002-9687-3556; Földvári-Nagy, László/0000-0002-3954-721X; Erőss, Bálint Mihály/0000-0003-3658-8427; Hosszúfalusi, Nóra/0000-0002-9469-372X; Hegyi, Péter/0000-0003-0399-7259; Mihály, Emese/0000-0003-3046-7341}
}

@article{MTMT:33667130,
	title = {No Association between Gastrointestinal Rebleeding and DOAC Therapy Resumption : A Systematic Review and Meta-Analysis},
	url = {https://m2.mtmt.hu/api/publication/33667130},
	author = {Pálinkás, Dániel and Teutsch, Brigitta and Gagyi , Endre and Engh, Marie Anne and Kalló, Patrícia and Veres, Dániel and Földvári-Nagy, László and Hosszúfalusi, Nóra and Hegyi, Péter and Erőss, Bálint Mihály},
	doi = {10.3390/biomedicines11020554},
	journal-iso = {BIOMEDICINES},
	journal = {BIOMEDICINES},
	volume = {11},
	unique-id = {33667130},
	abstract = {There are recommendations for anticoagulation resumption after gastrointestinal bleeding (GIB), although data addressing this topic by direct oral anticoagulants (DOACs)-treated patients is lacking. We aim to determine the safety and efficacy of restarting DOACs after GIB.Studies that reported rebleeding, thromboembolic events, and mortality after restarting or withholding DOACs were selected. The systematic research was conducted in five databases (MEDLINE, EMBASE, CENTRAL, Web of Science, and Scopus). The random effect model was implemented to calculate the pooled odds ratio (OR). The ROBINS-I tool was used for risk of bias assessment, and the certainty of the evidence was evaluated with the GRADE approach.Four retrospective cohort studies (1722 patients) were included in the meta-analysis. We did not find a significant increase in the risk of rebleeding in patients restarting DOACs after index GIB (OR = 1.12; 95% CI: 0.74-1.68). The outcomes of thromboembolic events and mortality data were not suitable for meta-analytic calculations. Single studies did not show statistically significant differences. Data quality assessment showed a serious overall risk of bias and very low quality of evidence (GRADE D).DOAC resumption after a GIB episode may not elevate the risk of rebleeding. However, the need for high-quality randomized clinical trials is crucial.},
	keywords = {SAFETY; EFFICACY; gastrointestinal hemorrhage; Non-vitamin K antagonist oral anticoagulant (NOAC); therapy resumption; [Meta-analysis]},
	year = {2023},
	eissn = {2227-9059},
	orcid-numbers = {Teutsch, Brigitta/0000-0002-9530-7886; Engh, Marie Anne/0000-0003-4269-5130; Veres, Dániel/0000-0002-9687-3556; Földvári-Nagy, László/0000-0002-3954-721X; Hosszúfalusi, Nóra/0000-0002-9469-372X; Hegyi, Péter/0000-0003-0399-7259; Erőss, Bálint Mihály/0000-0003-3658-8427}
}

@article{MTMT:34802732,
	title = {About one-in-three new onset diabetic ketosis cases is caused by ketosis-prone type 2 diabetes in adults: a systematic review and meta-analysis},
	url = {https://m2.mtmt.hu/api/publication/34802732},
	author = {Kovacs, A. and Bunduc, S. and Veres, D. S. and Palinkas, D. and Gagyi, E. B. and Marta, K. and Hegyi, J. P. and Eross, B. and Mihály, Emese and Sipter, Emese and Pánczél, Pál and Hegyi, P. and Hosszúfalusi, Nóra},
	journal-iso = {DIABETOLOGIA},
	journal = {DIABETOLOGIA},
	volume = {65},
	unique-id = {34802732},
	issn = {0012-186X},
	year = {2022},
	eissn = {1432-0428},
	pages = {S176-S177},
	orcid-numbers = {Mihály, Emese/0000-0003-3046-7341; Sipter, Emese/0000-0002-3730-3270; Pánczél, Pál/0000-0001-5337-9489; Hosszúfalusi, Nóra/0000-0002-9469-372X}
}

@article{MTMT:34138718,
	title = {KARDIOVASZKULÁRIS KOCKÁZAT KORAI KEZDETŰ ÉS HOSSZÚ BETEGSÉGTARTAMÚ 1-ES TÍPUSÚ CUKORBETEGSÉGBEN: NAGY RIZIKÓ – KEVÉS FIGYELEM},
	url = {https://m2.mtmt.hu/api/publication/34138718},
	author = {Ambrus, Viktória and Vida, Ádám and Somogyi, Anikó and Sármán, Beatrix and Nagy, Géza and Herold, Magdolna and Hosszúfalusi, Nóra and Sipter, Emese},
	journal-iso = {DIABETOLOGIA HUNGARICA},
	journal = {DIABETOLOGIA HUNGARICA},
	volume = {XXX.},
	unique-id = {34138718},
	issn = {1217-372X},
	year = {2022},
	eissn = {2560-0168},
	pages = {6-6},
	orcid-numbers = {Somogyi, Anikó/0000-0003-0807-260X; Hosszúfalusi, Nóra/0000-0002-9469-372X; Sipter, Emese/0000-0002-3730-3270}
}

@article{MTMT:34080912,
	title = {The safety and efficacy of direct oral anticagulant resumption following a gastrointestinal bleeding episode: a systematic review and meta-analysis},
	url = {https://m2.mtmt.hu/api/publication/34080912},
	author = {Palinkas, D and Teutsch, B and Gagyi , Endre and Engh, MA and Veres, DS and Hosszúfalusi, Nóra and Herszényi, L and Hegyi, P and Erőss, B},
	journal-iso = {UEG JOURNAL},
	journal = {UNITED EUROPEAN GASTROENTEROLOGY JOURNAL},
	volume = {10},
	unique-id = {34080912},
	issn = {2050-6406},
	year = {2022},
	eissn = {2050-6414},
	pages = {481-482},
	orcid-numbers = {Hosszúfalusi, Nóra/0000-0002-9469-372X}
}

@article{MTMT:34022784,
	title = {Az 1,5-anhidroglucitol és az anyagcserekontroll többi mutatója közötti összefüggés vizsgálata diabetes mellitusban},
	url = {https://m2.mtmt.hu/api/publication/34022784},
	author = {Rácz, Olivér and Barkai, László József and Salamonová, Blichová Lenka and Sipter, Emese and Hosszúfalusi, Nóra},
	journal-iso = {DIABETOLOGIA HUNGARICA},
	journal = {DIABETOLOGIA HUNGARICA},
	volume = {30},
	unique-id = {34022784},
	issn = {1217-372X},
	year = {2022},
	eissn = {2560-0168},
	pages = {86-87},
	orcid-numbers = {Sipter, Emese/0000-0002-3730-3270; Hosszúfalusi, Nóra/0000-0002-9469-372X}
}