@misc{MTMT:34794821, title = {Neural correlates of valence and arousal ratings responding to socio-emotional stimuli.}, url = {https://m2.mtmt.hu/api/publication/34794821}, author = {Rendes, Réka and Orsi, Gergely and Perlaki, Gábor and Bereczkei, Tamás and Deák, Anita}, unique-id = {34794821}, year = {2024}, orcid-numbers = {Bereczkei, Tamás/0000-0002-4665-3475; Deák, Anita/0000-0001-6862-4993} } @article{MTMT:34477406, title = {Volumetric alteration of brainstem in female migraineurs with and without aura}, url = {https://m2.mtmt.hu/api/publication/34477406}, author = {He, Mingchen and Kis-Jakab, Gréta and Komáromy, Hedvig and Perlaki, Gábor and Orsi, Gergely and Bosnyák, Edit and Rozgonyi, Renáta and John, Flóra and Trauninger, Anita and Eklicsné Lepenye, Katalin and Pfund, Zoltán}, doi = {10.1016/j.clineuro.2023.108089}, journal-iso = {CLIN NEUROL NEUROSUR}, journal = {CLINICAL NEUROLOGY AND NEUROSURGERY}, volume = {236}, unique-id = {34477406}, issn = {0303-8467}, abstract = {Brainstem descending modulatory circuits have been postulated to be involved in migraine. Differences in brainstem volume between migraineurs and healthy controls have been demonstrated in previous research, nevertheless, the effect of migraine aura on brainstem volume is still uncertain. The aim of this study was to investigate the brainstem volume in migraineurs and examine the effect of migraine aura on brainstem volume.Our study included 90 female migraine patients without white matter lesions. (29 migraine patients with aura (MwA) and 61 migraine patients without aura (MwoA) and 32 age-matched female healthy controls (HC). Using the FreeSurfer image analysis suite, the volumes of the entire brainstem and its subfields (medulla, pons, and midbrain) were measured and compared between migraine subgroups (MwA vs. MwoA) and the healthy control group. The possible effects of migraine characteristics (i.e., disease duration and migraine attack frequency) on brainstem volume were also investigated.Migraineurs had greater medulla volume (MwoA 3552 ± 459 mm3, MwA 3424 ± 448 mm3) than healthy controls (3236 ± 411 mm3). Statistically, MwA vs. HC p = 0.040, MwoA vs. HC p = 0.002, MwA vs. MwoA p = 0.555. A significant positive correlation was found between disease duration and the volume of medulla in the whole migraine group (r = 0.334, p = 0.001). Neither the whole brainstem nor its subfields were significantly different in volume between migraine subgroups.Brainstem volume changes in migraine are mainly localized to the medulla and not specific to the presence of aura.}, keywords = {morphometry; Magnetic Resonance Imaging; AURA; EPISODIC MIGRAINE; Brainstem volume}, year = {2024}, eissn = {1872-6968} } @article{MTMT:34420912, title = {Altered functional brain networks in problematic smartphone and social media use: resting-state fMRI study}, url = {https://m2.mtmt.hu/api/publication/34420912}, author = {Áfra, Eszter and Janszky, József Vladimír and Perlaki, Gábor and Orsi, Gergely and Nagy, Szilvia Anett and Arató, Ákos and Szente, Anna Tímea and Alhour, Husamalddin Ali Mohammad and Kis-Jakab, Gréta and Darnai, Gergely}, doi = {10.1007/s11682-023-00825-y}, journal-iso = {BRAIN IMAGING BEHAV}, journal = {BRAIN IMAGING AND BEHAVIOR}, unique-id = {34420912}, issn = {1931-7557}, abstract = {Nowadays, the limitless availability to the World Wide Web can lead to general Internet misuse and dependence. Currently, smartphone and social media use belong to the most prevalent Internet-related behavioral addiction forms. However, the neurobiological background of these Internet-related behavioral addictions is not sufficiently explored. In this study, these addiction forms were assessed with self-reported questionnaires. Resting-state functional magnetic resonance imaging was acquired for all participants ( n = 59, 29 males) to examine functional brain networks. The resting-state networks that were discovered using independent component analysis were analyzed to estimate within network differences. Significant negative associations with social media addiction and smartphone addiction were found in the language network, the lateral visual networks, the auditory network, the sensorimotor network, the executive network and the frontoparietal network. These results suggest that problematic smartphone and social media use are associated with sensory processing and higher cognitive functioning .}, year = {2024}, eissn = {1931-7565}, orcid-numbers = {Janszky, József Vladimír/0000-0001-6100-832X; Nagy, Szilvia Anett/0000-0001-6483-9209; Alhour, Husamalddin Ali Mohammad/0000-0001-5841-1652} } @article{MTMT:34113102, title = {Gray Matter Changes Following Mild COVID-19 : An MR Morphometric Study in Healthy Young People}, url = {https://m2.mtmt.hu/api/publication/34113102}, author = {Perlaki, Gábor and Darnai, Gergely and Arató, Ákos and Alhour, Husamalddin Ali Mohammad and Szente, Anna Tímea and Áfra, Eszter and Nagy, Szilvia Anett and Horváth, Réka and Kovács, Norbert and Dóczi, Tamás Péter and Orsi, Gergely and Janszky, József Vladimír}, doi = {10.1002/jmri.28970}, journal-iso = {JMRI - J MAGN RESON IM}, journal = {JOURNAL OF MAGNETIC RESONANCE IMAGING}, unique-id = {34113102}, issn = {1053-1807}, abstract = {Although COVID-19 is primarily an acute respiratory infection, 5%-40% of patients develop late and prolonged symptoms with frequent neurological complaints, known as long COVID syndrome. The presentation of the disease suggests that COVID infection may cause functional and/or morphological central nervous system alterations, but studies published in the literature report contradictory findings.To investigate the chronic effects of COVID-19 on cerebral grey matter in a group of young patients without comorbidities, with mild course of COVID infection and no medical complaints at the time of examination.Prospective.Thirty-eight young (age = 26.6 ± 5.0 years; male/female = 14/24), adult participants who recovered from mild COVID infection without a history of clinical long COVID and 37 healthy control subjects (age = 25.9 ± 2.8 years; male/female = 14/23).Three Tesla, 3D T1-weighted magnetization-prepared rapid gradient-echo, 2D T2-weighted turbo spin-echo.MRI-based morphometry and volumetry along with neuropsychological testing and self-assessed questionnaire.Fisher's exact test, Mann-Whitney U-test, and multiple linear regression analyses were used to assess differences between COVID and healthy control groups. P < 0.05 was used as cutoff for significance.In the COVID group, significantly lower bilateral mean cortical thickness (left/right-hemisphere: 2.51 ± 0.06 mm vs. 2.56 ± 0.07 mm, η2 p = 0.102/2.50 ± 0.06 mm vs. 2.54 ± 0.07 mm, η2 p = 0.101), lower subcortical gray matter (57881 ± 3998 mm3 vs. 60470 ± 5211 mm3 , η2 p = 0.100) and lower right olfactory bulb volume (52.28 ± 13.55 mm3 vs. 60.98 ± 15.8 mm3 , η2 p = 0.078) were found. In patients with moderate to severe anosmia, cortical thickness was significantly lower bilaterally, as compared to patients without olfactory function loss (left/right-hemisphere: 2.50 ± 0.06 mm vs. 2.56 ± 0.05 mm, η2 = 0.173/2.49 ± 0.06 mm vs. 2.55 ± 0.05 mm, η2 = 0.189). Using further exploratory analysis, significantly reduced cortical thickness was detected locally in the right lateral orbitofrontal cortex in the COVID group (2.53 ± 0.10 mm vs. 2.60 ± 0.09 mm, η2 p = 0.112).Even without any subjective or objective neurological complaints at the time of the MR scan, subjects in the COVID group showed gray matter alterations in cortical thickness and subcortical gray matter volume.2 TECHNICAL EFFICACY: Stage 3.}, keywords = {Brain; morphometry; cortical thickness; SARS-CoV-2}, year = {2024}, eissn = {1522-2586}, orcid-numbers = {Alhour, Husamalddin Ali Mohammad/0000-0001-5841-1652; Nagy, Szilvia Anett/0000-0001-6483-9209; Kovács, Norbert/0000-0002-7332-9240; Janszky, József Vladimír/0000-0001-6100-832X} } @misc{MTMT:34772738, title = {Ironsleep}, url = {https://m2.mtmt.hu/api/publication/34772738}, author = {Perlaki, Gábor and Hernádi, Gabriella and Pintér, Dávid and Rohonczi, Mirtill and Harmat, Márk and Aschermann, Zsuzsanna and Orsi, Gergely and Komoly, Sámuel and Janszky, József and Kovács, Norbert}, unique-id = {34772738}, year = {2023} } @misc{MTMT:34314191, title = {High neuroticism scorers show increased brain activation in response to negative social stimuli}, url = {https://m2.mtmt.hu/api/publication/34314191}, author = {Deák, Anita and Rendes, Réka and Várkonyi, Gergely and Orsi, Gergely and Perlaki, Gábor and Bereczkei, Tamás}, unique-id = {34314191}, year = {2023}, orcid-numbers = {Deák, Anita/0000-0001-6862-4993; Bereczkei, Tamás/0000-0002-4665-3475} } @article{MTMT:34207248, title = {The volume of the thalamus and hippocampus in a right-handed female episodic migraine group}, url = {https://m2.mtmt.hu/api/publication/34207248}, author = {He, Mingchen and Kis-Jakab, Gréta and Komáromy, Hedvig and Perlaki, Gábor and Orsi, Gergely and Bosnyák, Edit and Rozgonyi, Renáta and John, Flóra and Trauninger, Anita and Eklicsné Lepenye, Katalin and Pfund, Zoltán}, doi = {10.3389/fneur.2023.1254628}, journal-iso = {FRONT NEUR}, journal = {FRONTIERS IN NEUROLOGY}, volume = {14}, unique-id = {34207248}, issn = {1664-2295}, year = {2023}, eissn = {1664-2295} } @article{MTMT:34050785, title = {White matter hyperintensities associated with impulse control disorders in Parkinson's Disease}, url = {https://m2.mtmt.hu/api/publication/34050785}, author = {Hernádi, Gabriella and Perlaki, Gábor and Kovács, Márton and Pintér, Dávid and Orsi, Gergely and Janszky, József Vladimír and Kovács, Norbert}, doi = {10.1038/s41598-023-37054-8}, journal-iso = {SCI REP}, journal = {SCIENTIFIC REPORTS}, volume = {13}, unique-id = {34050785}, issn = {2045-2322}, abstract = {Impulse control disorders (ICDs) in Parkinson's disease (PD) are increasingly recognized as clinically significant non-motor features that potentially impair the quality of life. White matter hyperintensities (WMHs), detected by magnetic resonance imaging, are frequently observed in PD and can be associated with both motor- and certain non-motor symptoms. Given the limited number of non-motor features studied in this context, our aim was to reveal the potential association between the severity of WMHs and ICDs in PD. Fluid-attenuated inversion recovery magnetic resonance images were retrospectively evaluated in 70 patients with PD (48 males; 59.3 ± 10.1 years). The severity of WMHs was assessed by Fazekas scores and by the volume and number of supratentorial WMHs. ICDs were evaluated using the modified Minnesota Impulsive Disorders Interview. Significant interaction between age and the severity of WMHs was present for ICDs. In our younger patients (< 60.5 years), severity of WMHs was positively associated with ICDs (p = 0.004, p = 0.021, p < 0.001 and p < 0.001, respectively for periventricular white matter and total Fazekas scores and the volume and number of WMHs). Our study supports the hypothesis that WMHs of presumed vascular origin may contribute to ICDs in PD. Future prospective studies are needed to assess the prognostic relevance of this finding.}, year = {2023}, eissn = {2045-2322}, orcid-numbers = {Janszky, József Vladimír/0000-0001-6100-832X; Kovács, Norbert/0000-0002-7332-9240} } @misc{MTMT:34012058, title = {Fehérállományi hiperintenzitások és impulzus kontroll zavarok kapcsolata Parkinson-kórban}, url = {https://m2.mtmt.hu/api/publication/34012058}, author = {Kovács, Márton and Hernádi, Gabriella and Perlaki, Gábor and Pintér, Dávid and Orsi, Gergely and Janszky, József Vladimír and Kovács, Norbert}, unique-id = {34012058}, year = {2023}, orcid-numbers = {Janszky, József Vladimír/0000-0001-6100-832X; Kovács, Norbert/0000-0002-7332-9240} } @misc{MTMT:34012040, title = {A fecskefarok jel aszimmetria és a klinikai lateralitás kapcsolata Parkinson-kórban}, url = {https://m2.mtmt.hu/api/publication/34012040}, author = {Rohonczi, Mirtill and Perlaki, Gábor and Hernádi, Gabriella and Kovács, Norbert and Janszky, József Vladimír and Dóczi, Tamás Péter and Harmat, Márk and Pintér, Dávid and Aschermann, Zsuzsanna}, unique-id = {34012040}, year = {2023}, orcid-numbers = {Kovács, Norbert/0000-0002-7332-9240; Janszky, József Vladimír/0000-0001-6100-832X} }