TY - JOUR AU - Kovács, Anita AU - Falusi, Fanni AU - Gácsi, Attila AU - Budai-Szűcs, Mária AU - Csányi, Erzsébet AU - Veréb, Zoltán AU - Monostori, Tamás AU - Pannonhalminé Csóka, Ildikó AU - Berkó, Szilvia TI - Formulation and investigation of hydrogels containing an increased level of diclofenac sodium using risk assessment tools JF - EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES J2 - EUR J PHARM SCI VL - 193 PY - 2024 PG - 15 SN - 0928-0987 DO - 10.1016/j.ejps.2023.106666 UR - https://m2.mtmt.hu/api/publication/34428028 ID - 34428028 N1 - HCEMM-USZ Skin Research Group, Szeged, Hungary LA - English DB - MTMT ER - TY - JOUR AU - Szilágyi, Barnabás Áron AU - Gyarmati, Benjámin Sándor AU - L. Kiss, Eszter AU - Budai-Szűcs, Mária AU - Misra, Anil AU - Csányi, Erzsébet AU - Nagyné László, Krisztina AU - Szilágyi, András Ferenc TI - In situ gelation of thiolated poly(aspartic acid) derivatives through oxidant-free disulfide formation for ophthalmic drug delivery JF - COLLOIDS AND SURFACES B: BIOINTERFACES J2 - COLLOID SURFACE B VL - 225 PY - 2023 PG - 10 SN - 0927-7765 DO - 10.1016/j.colsurfb.2023.113254 UR - https://m2.mtmt.hu/api/publication/33734502 ID - 33734502 N1 - Department of Physical Chemistry and Materials Science, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3, Budapest, H-1111, Hungary Institute of Pharmaceutical Technology and Regulatory Affairs, Faculty of Pharmacy, University of Szeged, Eötvös u. 6, Szeged, H-6720, Hungary Pharmidex Pharmaceutical Services, Office 3.05, 1 King Street, London, EC2V 8AU, United Kingdom CODEN: CSBBE Correspondence Address: Szilágyi, A.; Department of Physical Chemistry and Materials Science, Műegyetem rkp. 3, Hungary; email: szilagyi.andras@vbk.bme.hu LA - English DB - MTMT ER - TY - JOUR AU - Budai-Szűcs, Mária AU - L. Kiss, Eszter AU - Soós, Judit AU - Csányi, Erzsébet TI - Innovatív szemészeti készítmények formulálása JF - GYÓGYSZERÉSZET J2 - GYÓGYSZERÉSZET VL - 66 PY - 2022 IS - 10 SP - 511 EP - 517 PG - 7 SN - 0017-6036 UR - https://m2.mtmt.hu/api/publication/33547874 ID - 33547874 LA - Hungarian DB - MTMT ER - TY - JOUR AU - László, Szabolcs AU - Bátai, István Zoárd AU - Berkó, Szilvia AU - Csányi, Erzsébet AU - Dombi, Ágnes AU - Pozsgai, Gábor AU - Bölcskei, Kata AU - Botz, Lajos AU - Wagner, Ödön AU - Pintér, Erika TI - Development of Capsaicin-Containing Analgesic Silicone-Based Transdermal Patches JF - PHARMACEUTICALS J2 - PHARMACEUTICALS-BASE VL - 15 PY - 2022 IS - 10 PG - 17 SN - 1424-8247 DO - 10.3390/ph15101279 UR - https://m2.mtmt.hu/api/publication/33202693 ID - 33202693 N1 - Department of Inorganic and Analytical Chemistry, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3, Budapest, H-1111, Hungary Department of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti u. 12, Pécs, H-7624, Hungary Molecular Pharmacology Research Group, Szentágothai Research Centre, University of Pécs, Ifjúság ú. 20, Pécs, H-7624, Hungary Institute of Pharmaceutical Technology and Regulatory Affairs, Faculty of Pharmacy, University of Szeged, Eötvös str. 6, Szeged, H-6720, Hungary Department of Pharmaceutics and Central Clinical Pharmacy, Faculty of Pharmacy, University of Pécs, Honvéd u. 3, Pécs, H-7624, Hungary Cited By :1 Export Date: 20 September 2023 Correspondence Address: Pozsgai, G.; Department of Pharmacology and Pharmacotherapy, Szigeti u. 12, Hungary; email: pozsgai.gabor@pte.hu AB - Transdermal therapeutic systems (TTSs) enable convenient dosing in drug therapy. Modified silicone-polymer-based patches are well-controlled and cost-effective matrix diffusion systems. In the present study, we investigated the substance release properties, skin penetration, and analgesic effect of this type of TTS loaded with low-dose capsaicin. Release properties were measured in Franz diffusion cell and continuous flow-through cell approaches. Capsaicin was detected with HPLC-UV and UV spectrophotometry. Raman spectroscopy was conducted on human skin samples exposed to the TTS. A surgical incision or carrageenan injection was performed on one hind paw of male Wistar rats. TTSs were applied to the epilated dorsal skin. Patches were kept on the animals for 6 h. The thermal hyperalgesia and mechanical pain threshold of the hind paws were detected. Patches exhibited controlled, zero-order kinetic capsaicin release. According to the Raman mapping, capsaicin penetrated into the epidermis and dermis of human skin, where the target receptors are expressed. The thermal pain threshold drop of the operated rat paws was reversed by capsaicin treatment compared to that of animals treated with control patches. It was concluded that our modified silicone-polymer-based capsaicin-containing TTS is suitable for the relief of traumatic and inflammatory pain. LA - English DB - MTMT ER - TY - JOUR AU - Szoleczky, Réka AU - Budai-Szűcs, Mária AU - Csányi, Erzsébet AU - Berkó, Szilvia AU - Tonka-Nagy, Péter AU - Pannonhalminé Csóka, Ildikó AU - Kovács, Anita TI - Analytical Quality by Design (AQbD) Approach to the Development of In Vitro Release Test for Topical Hydrogel JF - PHARMACEUTICS J2 - PHARMACEUTICS VL - 14 PY - 2022 IS - 4 PG - 18 SN - 1999-4923 DO - 10.3390/pharmaceutics14040707 UR - https://m2.mtmt.hu/api/publication/32760254 ID - 32760254 LA - English DB - MTMT ER - TY - JOUR AU - Falusi, Fanni AU - Budai-Szűcs, Mária AU - Csányi, Erzsébet AU - Berkó, Szilvia AU - Spaits, Tamás AU - Pannonhalminé Csóka, Ildikó AU - Kovács, Anita TI - Investigation of the effect of polymers on dermal foam properties using the QbD approach JF - EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES J2 - EUR J PHARM SCI VL - 173 PY - 2022 PG - 15 SN - 0928-0987 DO - 10.1016/j.ejps.2022.106160 UR - https://m2.mtmt.hu/api/publication/32729356 ID - 32729356 LA - English DB - MTMT ER - TY - JOUR AU - Kis, Nikolett AU - Kovács, Anita AU - Budai-Szűcs, Mária AU - Erős, Gábor AU - Csányi, Erzsébet AU - Berkó, Szilvia TI - The effect of non-invasive dermal electroporation on skin barrier function and skin permeation in combination with different dermal formulations JF - JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY J2 - J DRUG DELIV SCI TEC VL - 69 PY - 2022 PG - 8 SN - 1773-2247 DO - 10.1016/j.jddst.2022.103161 UR - https://m2.mtmt.hu/api/publication/32650914 ID - 32650914 LA - English DB - MTMT ER - TY - CHAP AU - Kovács, Anita AU - Csányi, Erzsébet AU - Bögöthy, Zsolt AU - Budai-Szűcs, Mária AU - Pannonhalminé Csóka, Ildikó AU - Berkó, Szilvia ED - S., n. TI - Termálvíz koncentrátum tartalmú kozmetikai készítmény fejlesztése T2 - MKE Kozmetikai Szimpózium 2021, 50 éves volt 2020-ban az MKE Kozmetikai és Háztartásvegyipari Társaság PB - Magyar Kémikusok Egyesülete (MKE) CY - h.n. SN - 9786156018083 PY - 2021 SP - 16 UR - https://m2.mtmt.hu/api/publication/32529606 ID - 32529606 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Kovács, Anita AU - Zsikó, Stella AU - Falusi, Fanni AU - Csányi, Erzsébet AU - Budai-Szűcs, Mária AU - Pannonhalminé Csóka, Ildikó AU - Berkó, Szilvia TI - Comparison of Synthetic Membranes to Heat-Separated Human Epidermis in Skin Permeation Studies In Vitro JF - PHARMACEUTICS J2 - PHARMACEUTICS VL - 13 PY - 2021 IS - 12 PG - 14 SN - 1999-4923 DO - 10.3390/pharmaceutics13122106 UR - https://m2.mtmt.hu/api/publication/32528256 ID - 32528256 LA - English DB - MTMT ER - TY - GEN AU - Kis, Nikolett AU - Csányi, Erzsébet AU - Budai-Szűcs, Mária AU - Kovács, Anita AU - Gácsi, Attila AU - Berkó, Szilvia TI - Investigation of physiological skin parameters influenced by penetration enhancer methods PY - 2021 UR - https://m2.mtmt.hu/api/publication/32152285 ID - 32152285 LA - English DB - MTMT ER -