TY - GEN AU - Fröhlich, Georgina TI - A deformábilis képregisztráció szerepe méhnyakdaganatok kombinált tele- és brachyterápiájának biológiai dózisösszegzésében PY - 2024 UR - https://m2.mtmt.hu/api/publication/34795177 ID - 34795177 N1 - Előadás LA - Hungarian DB - MTMT ER - TY - JOUR AU - Lévay, Bernadett AU - Alexandra, Kiss AU - Fröhlich, Georgina AU - Tóth, Erika AU - András, Slezák AU - Péter, Ilona AU - Oberna, Ferenc AU - Orsolya, Dohán TI - No correlation between PD-L1 and NIS expression in lymph node metastatic papillary thyroid carcinoma JF - RESEARCH SQUARE : PREPRINT PLATFORM J2 - RES SQUARE VL - & PY - 2024 SP - & SN - 2693-5015 DO - 10.21203/rs.3.rs-4145941/v1 UR - https://m2.mtmt.hu/api/publication/34766075 ID - 34766075 LA - English DB - MTMT ER - TY - JOUR AU - Gesztesi, László AU - Kocsis, Zsuzsa AU - Jorgo, Kliton AU - Fröhlich, Georgina AU - Polgár, Csaba AU - Ágoston, Péter Zoltán TI - Alterations of Sexual and Erectile Functions after Brachytherapy for Prostate Cancer Based on Patient-Reported Questionnaires JF - PROSTATE CANCER J2 - PROSTATE CANC VL - 2024 PY - 2024 PG - 13 SN - 2090-3111 DO - 10.1155/2024/5729185 UR - https://m2.mtmt.hu/api/publication/34544359 ID - 34544359 AB - The aim of the study was to compare the side effects of high-dose-rate brachytherapy (HDRBT) and low-dose-rate brachytherapy (LDRBT), with a particular focus on the effects on sexual functions and sexual well-being (PROMOBRA study, NCT02258087). Localized low-risk and low-intermediate-risk prostate cancer patients were treated with mono LDR (N = 123, 145 Gy dose) or mono HDR brachytherapy (N = 117, 19/21 Gy). Prior to the treatment and during follow-up (at 3, 6, 9, 12, 18, and 24 months after treatment, and then annually after two years), patients completed patient-reported outcome measurement (PROM) questionnaires EORTC QLQ-PR-25, International Index of Erectile Function (IIEF), and IIEF-5 (SHIM). We compared the patients in different group breakdowns (HDR vs. LDR, hormone naïve and hormone-receiving HDR vs. LDR, hormone naïve and hormone-receiving patients in general, and 19 Gy HDR vs. 21 Gy HDR). In the hormone-naive LDR group, erectile function, orgasm function, sexual desire, satisfaction with intercourse, and overall satisfaction functions significantly decreased compared to baseline throughout the whole follow-up period. However, there were significant decreases in function at a maximum of three time points after HDR therapy without hormone therapy. In hormone-receiving patients, the orgasm function was significantly better in the HDR group at multiple time points compared to the baseline, and sexual desire improved at four time points. According to our results, both LDRBT and HDRBT can be safely administered to patients with localized prostate cancer. In hormone-naive patients, the HDR group showed only recovering decreases in sexual functions, while the LDR group showed a lasting decline in multiple areas. Thus, HDR appears to be more advantageous to hormone-naive patients. LA - English DB - MTMT ER - TY - JOUR AU - Lévay, Bernadett AU - Tóth, Erika AU - Péter, Ilona AU - Kiss, Alexandra AU - Fröhlich, Georgina AU - Dohán, Orsolya AU - Boér, András AU - Oberna, Ferenc TI - Nyaki áttétet adó papillaris pajzsmirigyrák sebészi kezelésének eredményei - 5 éves anyagunk feldolgozása JF - ORVOSI HETILAP J2 - ORV HETIL VL - 165 PY - 2024 IS - 3 SP - 83 EP - 88 PG - 6 SN - 0030-6002 DO - 10.1556/650.2024.32960 UR - https://m2.mtmt.hu/api/publication/34517822 ID - 34517822 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Czirbesz, Kata AU - Liszkay, Gabriella AU - Baranyai, Fanni AU - Balatoni, Tímea AU - Kozéki, Zsófia AU - Kispál, Mihály Tamás AU - Fröhlich, Georgina AU - Hunyadi, Karen AU - Danyi, Tímea TI - 225 BRAF-MEK gátló kezelésben részesült beteg túlélési adatainak elemzése a terápia alatt alkalmazott dózisredukciók függvényében JF - BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE J2 - BVSZ VL - 99 PY - 2023 IS - 6 SP - 424 EP - 425 PG - 2 SN - 0006-7768 UR - https://m2.mtmt.hu/api/publication/34437515 ID - 34437515 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Ferenczi, Örs AU - Major, Tibor AU - Fröhlich, Georgina AU - Mihály, Dalma AU - Tódor, István Szabolcs AU - Polgár, Csaba AU - Akiyama, Hironori AU - Bukovszky, Botond AU - Takácsi-Nagy, Zoltán TI - Dosimetric comparison of postoperative interstitial high-dose-rate brachytherapy and modern external beam radiotherapy modalities in tongue and floor of the mouth tumours in terms of doses to critical organs. JF - RADIOLOGY AND ONCOLOGY J2 - RADIOL ONCOL VL - 57 PY - 2023 IS - 4 SP - 516 EP - 523 PG - 8 SN - 1318-2099 DO - 10.2478/raon-2023-0050 UR - https://m2.mtmt.hu/api/publication/34415084 ID - 34415084 AB - The aim of the study was to dosimetrically compare interstitial high-dose-rate (HDR) brachytherapy (BT) and modern external beam radiotherapy modalities, as volumetric modulated arc therapy (VMAT) and stereotactic radiotherapy with Cyberknife (CK) of tumours of the tongue and floor of the mouth in terms of dose to the critical organs.In National Institute of Oncology, Budapest, between March 2013 and August 2022 twenty patients (11 male/9 female) with stage T1-3N0M0 tongue (n = 14) and floor of mouth (n = 6) tumours received postoperative radiotherapy because of close/positive surgical margin and/or lymphovascular and/or perineural invasion. High-dose-rate interstitial brachytherapy applying flexible plastic catheters with a total dose of 15 × 3 Gy was used for treatment. In addition to BT plans VMAT and stereotactic CK plans were also made in all cases, using the same fractionation scheme and dose prescription. As for the organs at risk, the doses to the mandible, the ipsilateral and the contralateral salivary glands were compared.The mean volume of the planning target volume (PTV) was 12.5 cm3, 26.5 cm3 and 17.5 cm3 in BT, VMAT and CK techniques, respectively, due to different safety margin protocols. The dose to the mandible was the most favourable with BT, as for the salivary glands (parotid and submandibular) the CK technique resulted in the lowest dose. The highest dose to the critical organs was observed with the VMAT technique. The mean values of D2cm3 and D0.1cm3 for the critical organs were as follows for BT, VMAT and CK plans: 47.4% and 73.9%, 92.2% and 101.8%, 68.4% and 92.3% for the mandible, 4.8% and 6.7%, 7.3% and 13.8%, 2.3% and 5.1% for the ipsilateral parotid gland, 3.5% and 4.9%, 6.8% and 10.9%, 1.5% and 3.3% for the contralateral parotid gland, 7.3% and 9.4%, 9.0% and 14.3%, 3.6% and 5.6% for the contralateral submandibular gland.The present results confirm that BT, despite being an invasive technique, is dosimetrically clearly beneficial in the treatment of oral cavity tumours and is a modality worth considering when applying radiotherapy, not only as definitive treatment, but also postoperatively. The use of the CK in the head and neck region requires further investigation. LA - English DB - MTMT ER - TY - JOUR AU - Wilhelm, Imola Mária AU - Dékány, Éva Katalin AU - Hatvani, István Gábor AU - Fröhlich, Georgina AU - Micskei, Zoltán Imre AU - Pach, Péter Pál AU - Toldy, Andrea AU - Solymosi, Katalin AU - Szentgáli-Tóth, Boldizsár Artúr AU - Lengyel, Balázs TI - A Fiatal Kutatók Akadémiájának javaslatai a magyarországi fiatal kutatók helyzetének javítására JF - MAGYAR TUDOMÁNY J2 - MAGYAR TUDOMÁNY VL - 184 PY - 2023 IS - 12 SP - 1544 EP - 1565 PG - 7 SN - 0025-0325 DO - 10.1556/2065.184.2023.12.11 UR - https://m2.mtmt.hu/api/publication/34412830 ID - 34412830 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Németh, Brigitta AU - Munkácsy, B AU - Vida, Zsófia Viktória AU - Fröhlich, Georgina AU - Hatvani, István Gábor AU - Tóth, György AU - Solymosi, Katalin AU - Máté, Ágnes AU - Lőrincz, László AU - Lengyel, Balázs TI - Egyenlőtlenségek a magyarországi fiatal kutatók között: tanulságok a Fiatal Kutatók Akadémiájának 2021-es felméréséből JF - MAGYAR TUDOMÁNY J2 - MAGYAR TUDOMÁNY VL - 184 PY - 2023 IS - 12 SP - 1529 EP - 1543 PG - 15 SN - 0025-0325 DO - 10.1556/2065.184.2023.12.10 UR - https://m2.mtmt.hu/api/publication/34412825 ID - 34412825 N1 - A tanulmány az MTA és az FKA kiadásában megjelent, A fiatalok helyzete az akadémiai pályán c. jelentés alapján készült (Bp. 2022. [33192830]) LA - Hungarian DB - MTMT ER - TY - JOUR AU - Ortutay, Rita AU - Jánváry, Zsolt Levente AU - Stelczer, Gábor AU - Fröhlich, Georgina AU - Takácsi-Nagy, Zoltán AU - Polgár, Csaba TI - Májáttétek CyberKnife készülékkel végzett sztereotaxiás besugárzásának eredményessé JF - MAGYAR ONKOLÓGIA J2 - MAGYAR ONKOLÓGIA VL - 67 PY - 2023 IS - 1. szuppl. SP - 48 EP - 48 PG - 1 SN - 0025-0244 UR - https://m2.mtmt.hu/api/publication/34344007 ID - 34344007 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Fröhlich, Georgina AU - Nguyen, Anhhong Nhung AU - Vízkeleti, Júlia AU - Heintz, Ádám AU - Major, Tibor AU - Takácsi-Nagy, Zoltán AU - Polgár, Csaba TI - Méhnyakdaganatok MR-vezérelt adaptív kombinált intersticiális-intrakavitális brachyterápiájának bevezetése az Országos Onkológiai Intézetben JF - MAGYAR ONKOLÓGIA J2 - MAGYAR ONKOLÓGIA VL - 67 PY - 2023 IS - 1. szuppl. SP - 24 EP - 25 PG - 2 SN - 0025-0244 UR - https://m2.mtmt.hu/api/publication/34342261 ID - 34342261 LA - Hungarian DB - MTMT ER -