@misc{MTMT:34795177, title = {A deformábilis képregisztráció szerepe méhnyakdaganatok kombinált tele- és brachyterápiájának biológiai dózisösszegzésében}, url = {https://m2.mtmt.hu/api/publication/34795177}, author = {Fröhlich, Georgina}, unique-id = {34795177}, year = {2024}, orcid-numbers = {Fröhlich, Georgina/0000-0001-6428-6536} } @article{MTMT:34766075, title = {No correlation between PD-L1 and NIS expression in lymph node metastatic papillary thyroid carcinoma}, url = {https://m2.mtmt.hu/api/publication/34766075}, author = {Lévay, Bernadett and Alexandra, Kiss and Fröhlich, Georgina and Tóth, Erika and András, Slezák and Péter, Ilona and Oberna, Ferenc and Orsolya, Dohán}, doi = {10.21203/rs.3.rs-4145941/v1}, journal-iso = {RES SQUARE}, journal = {RESEARCH SQUARE : PREPRINT PLATFORM}, volume = {&}, unique-id = {34766075}, year = {2024}, eissn = {2693-5015}, pages = {&}, orcid-numbers = {Lévay, Bernadett/0000-0001-7583-5123; Fröhlich, Georgina/0000-0001-6428-6536; Tóth, Erika/0000-0003-2054-8447; Oberna, Ferenc/0000-0002-2396-2937} } @article{MTMT:34544359, title = {Alterations of Sexual and Erectile Functions after Brachytherapy for Prostate Cancer Based on Patient-Reported Questionnaires}, url = {https://m2.mtmt.hu/api/publication/34544359}, author = {Gesztesi, László and Kocsis, Zsuzsa and Jorgo, Kliton and Fröhlich, Georgina and Polgár, Csaba and Ágoston, Péter Zoltán}, doi = {10.1155/2024/5729185}, journal-iso = {PROSTATE CANC}, journal = {PROSTATE CANCER}, volume = {2024}, unique-id = {34544359}, issn = {2090-3111}, abstract = {The aim of the study was to compare the side effects of high-dose-rate brachytherapy (HDRBT) and low-dose-rate brachytherapy (LDRBT), with a particular focus on the effects on sexual functions and sexual well-being (PROMOBRA study, NCT02258087). Localized low-risk and low-intermediate-risk prostate cancer patients were treated with mono LDR (N = 123, 145 Gy dose) or mono HDR brachytherapy (N = 117, 19/21 Gy). Prior to the treatment and during follow-up (at 3, 6, 9, 12, 18, and 24 months after treatment, and then annually after two years), patients completed patient-reported outcome measurement (PROM) questionnaires EORTC QLQ-PR-25, International Index of Erectile Function (IIEF), and IIEF-5 (SHIM). We compared the patients in different group breakdowns (HDR vs. LDR, hormone naïve and hormone-receiving HDR vs. LDR, hormone naïve and hormone-receiving patients in general, and 19 Gy HDR vs. 21 Gy HDR). In the hormone-naive LDR group, erectile function, orgasm function, sexual desire, satisfaction with intercourse, and overall satisfaction functions significantly decreased compared to baseline throughout the whole follow-up period. However, there were significant decreases in function at a maximum of three time points after HDR therapy without hormone therapy. In hormone-receiving patients, the orgasm function was significantly better in the HDR group at multiple time points compared to the baseline, and sexual desire improved at four time points. According to our results, both LDRBT and HDRBT can be safely administered to patients with localized prostate cancer. In hormone-naive patients, the HDR group showed only recovering decreases in sexual functions, while the LDR group showed a lasting decline in multiple areas. Thus, HDR appears to be more advantageous to hormone-naive patients.}, year = {2024}, eissn = {2090-312X}, orcid-numbers = {Kocsis, Zsuzsa/0000-0002-4336-3325; Jorgo, Kliton/0000-0002-0325-6795; Fröhlich, Georgina/0000-0001-6428-6536; Polgár, Csaba/0000-0001-7245-0762; Ágoston, Péter Zoltán/0000-0003-0264-630X} } @article{MTMT:34517822, title = {Nyaki áttétet adó papillaris pajzsmirigyrák sebészi kezelésének eredményei - 5 éves anyagunk feldolgozása}, url = {https://m2.mtmt.hu/api/publication/34517822}, author = {Lévay, Bernadett and Tóth, Erika and Péter, Ilona and Kiss, Alexandra and Fröhlich, Georgina and Dohán, Orsolya and Boér, András and Oberna, Ferenc}, doi = {10.1556/650.2024.32960}, journal-iso = {ORV HETIL}, journal = {ORVOSI HETILAP}, volume = {165}, unique-id = {34517822}, issn = {0030-6002}, year = {2024}, eissn = {1788-6120}, pages = {83-88}, orcid-numbers = {Lévay, Bernadett/0000-0001-7583-5123; Tóth, Erika/0000-0003-2054-8447; Fröhlich, Georgina/0000-0001-6428-6536; Dohán, Orsolya/0000-0001-6235-5657; Oberna, Ferenc/0000-0002-2396-2937} } @article{MTMT:34437515, title = {225 BRAF-MEK gátló kezelésben részesült beteg túlélési adatainak elemzése a terápia alatt alkalmazott dózisredukciók függvényében}, url = {https://m2.mtmt.hu/api/publication/34437515}, author = {Czirbesz, Kata and Liszkay, Gabriella and Baranyai, Fanni and Balatoni, Tímea and Kozéki, Zsófia and Kispál, Mihály Tamás and Fröhlich, Georgina and Hunyadi, Karen and Danyi, Tímea}, journal-iso = {BVSZ}, journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE}, volume = {99}, unique-id = {34437515}, issn = {0006-7768}, year = {2023}, eissn = {2064-261X}, pages = {424-425}, orcid-numbers = {Liszkay, Gabriella/0000-0001-6161-2033; Balatoni, Tímea/0000-0003-1311-1853; Fröhlich, Georgina/0000-0001-6428-6536} } @article{MTMT:34415084, title = {Dosimetric comparison of postoperative interstitial high-dose-rate brachytherapy and modern external beam radiotherapy modalities in tongue and floor of the mouth tumours in terms of doses to critical organs.}, url = {https://m2.mtmt.hu/api/publication/34415084}, author = {Ferenczi, Örs and Major, Tibor and Fröhlich, Georgina and Mihály, Dalma and Tódor, István Szabolcs and Polgár, Csaba and Akiyama, Hironori and Bukovszky, Botond and Takácsi-Nagy, Zoltán}, doi = {10.2478/raon-2023-0050}, journal-iso = {RADIOL ONCOL}, journal = {RADIOLOGY AND ONCOLOGY}, volume = {57}, unique-id = {34415084}, issn = {1318-2099}, abstract = {The aim of the study was to dosimetrically compare interstitial high-dose-rate (HDR) brachytherapy (BT) and modern external beam radiotherapy modalities, as volumetric modulated arc therapy (VMAT) and stereotactic radiotherapy with Cyberknife (CK) of tumours of the tongue and floor of the mouth in terms of dose to the critical organs.In National Institute of Oncology, Budapest, between March 2013 and August 2022 twenty patients (11 male/9 female) with stage T1-3N0M0 tongue (n = 14) and floor of mouth (n = 6) tumours received postoperative radiotherapy because of close/positive surgical margin and/or lymphovascular and/or perineural invasion. High-dose-rate interstitial brachytherapy applying flexible plastic catheters with a total dose of 15 × 3 Gy was used for treatment. In addition to BT plans VMAT and stereotactic CK plans were also made in all cases, using the same fractionation scheme and dose prescription. As for the organs at risk, the doses to the mandible, the ipsilateral and the contralateral salivary glands were compared.The mean volume of the planning target volume (PTV) was 12.5 cm3, 26.5 cm3 and 17.5 cm3 in BT, VMAT and CK techniques, respectively, due to different safety margin protocols. The dose to the mandible was the most favourable with BT, as for the salivary glands (parotid and submandibular) the CK technique resulted in the lowest dose. The highest dose to the critical organs was observed with the VMAT technique. The mean values of D2cm3 and D0.1cm3 for the critical organs were as follows for BT, VMAT and CK plans: 47.4% and 73.9%, 92.2% and 101.8%, 68.4% and 92.3% for the mandible, 4.8% and 6.7%, 7.3% and 13.8%, 2.3% and 5.1% for the ipsilateral parotid gland, 3.5% and 4.9%, 6.8% and 10.9%, 1.5% and 3.3% for the contralateral parotid gland, 7.3% and 9.4%, 9.0% and 14.3%, 3.6% and 5.6% for the contralateral submandibular gland.The present results confirm that BT, despite being an invasive technique, is dosimetrically clearly beneficial in the treatment of oral cavity tumours and is a modality worth considering when applying radiotherapy, not only as definitive treatment, but also postoperatively. The use of the CK in the head and neck region requires further investigation.}, keywords = {Brachytherapy; Dosimetry; Cyberknife; HDR; Stereotactic; VMAT; floor of mouth tumour; tongue tumour}, year = {2023}, eissn = {1581-3207}, pages = {516-523}, orcid-numbers = {Major, Tibor/0000-0002-4672-6910; Fröhlich, Georgina/0000-0001-6428-6536; Mihály, Dalma/0000-0003-4912-8577; Tódor, István Szabolcs/0000-0002-5650-377X; Polgár, Csaba/0000-0001-7245-0762; Bukovszky, Botond/0000-0001-6418-5719; Takácsi-Nagy, Zoltán/0000-0002-3261-0271} } @article{MTMT:34412830, title = {A Fiatal Kutatók Akadémiájának javaslatai a magyarországi fiatal kutatók helyzetének javítására}, url = {https://m2.mtmt.hu/api/publication/34412830}, author = {Wilhelm, Imola Mária and Dékány, Éva Katalin and Hatvani, István Gábor and Fröhlich, Georgina and Micskei, Zoltán Imre and Pach, Péter Pál and Toldy, Andrea and Solymosi, Katalin and Szentgáli-Tóth, Boldizsár Artúr and Lengyel, Balázs}, doi = {10.1556/2065.184.2023.12.11}, journal-iso = {MAGYAR TUDOMÁNY}, journal = {MAGYAR TUDOMÁNY}, volume = {184}, unique-id = {34412830}, issn = {0025-0325}, year = {2023}, eissn = {1588-1245}, pages = {1544-1565}, orcid-numbers = {Wilhelm, Imola Mária/0000-0003-2366-7337; Dékány, Éva Katalin/0000-0002-0737-1774; Hatvani, István Gábor/0000-0002-9262-7315; Fröhlich, Georgina/0000-0001-6428-6536; Micskei, Zoltán Imre/0000-0003-1846-261X; Toldy, Andrea/0000-0003-3569-1828; Solymosi, Katalin/0000-0001-5246-2547; Szentgáli-Tóth, Boldizsár Artúr/0000-0001-5637-8991} } @article{MTMT:34412825, title = {Egyenlőtlenségek a magyarországi fiatal kutatók között: tanulságok a Fiatal Kutatók Akadémiájának 2021-es felméréséből}, url = {https://m2.mtmt.hu/api/publication/34412825}, author = {Németh, Brigitta and Munkácsy, B and Vida, Zsófia Viktória and Fröhlich, Georgina and Hatvani, István Gábor and Tóth, György and Solymosi, Katalin and Máté, Ágnes and Lőrincz, László and Lengyel, Balázs}, doi = {10.1556/2065.184.2023.12.10}, journal-iso = {MAGYAR TUDOMÁNY}, journal = {MAGYAR TUDOMÁNY}, volume = {184}, unique-id = {34412825}, issn = {0025-0325}, year = {2023}, eissn = {1588-1245}, pages = {1529-1543}, orcid-numbers = {Németh, Brigitta/0009-0000-3933-3193; Fröhlich, Georgina/0000-0001-6428-6536; Hatvani, István Gábor/0000-0002-9262-7315; Solymosi, Katalin/0000-0001-5246-2547} } @article{MTMT:34344007, title = {Májáttétek CyberKnife készülékkel végzett sztereotaxiás besugárzásának eredményessé}, url = {https://m2.mtmt.hu/api/publication/34344007}, author = {Ortutay, Rita and Jánváry, Zsolt Levente and Stelczer, Gábor and Fröhlich, Georgina and Takácsi-Nagy, Zoltán and Polgár, Csaba}, journal-iso = {MAGYAR ONKOLÓGIA}, journal = {MAGYAR ONKOLÓGIA}, volume = {67}, unique-id = {34344007}, issn = {0025-0244}, year = {2023}, eissn = {2060-0399}, pages = {48-48}, orcid-numbers = {Jánváry, Zsolt Levente/0000-0002-4583-4901; Stelczer, Gábor/0000-0003-4984-6165; Fröhlich, Georgina/0000-0001-6428-6536; Takácsi-Nagy, Zoltán/0000-0002-3261-0271; Polgár, Csaba/0000-0001-7245-0762} } @article{MTMT:34342261, title = {Méhnyakdaganatok MR-vezérelt adaptív kombinált intersticiális-intrakavitális brachyterápiájának bevezetése az Országos Onkológiai Intézetben}, url = {https://m2.mtmt.hu/api/publication/34342261}, author = {Fröhlich, Georgina and Nguyen, Anhhong Nhung and Vízkeleti, Júlia and Heintz, Ádám and Major, Tibor and Takácsi-Nagy, Zoltán and Polgár, Csaba}, journal-iso = {MAGYAR ONKOLÓGIA}, journal = {MAGYAR ONKOLÓGIA}, volume = {67}, unique-id = {34342261}, issn = {0025-0244}, year = {2023}, eissn = {2060-0399}, pages = {24-25}, orcid-numbers = {Fröhlich, Georgina/0000-0001-6428-6536; Vízkeleti, Júlia/0000-0002-1566-1165; Major, Tibor/0000-0002-4672-6910; Takácsi-Nagy, Zoltán/0000-0002-3261-0271; Polgár, Csaba/0000-0001-7245-0762} }