@article{MTMT:3228021, title = {Food and water intake, body temperature and metabolic consequences of interleukin-1beta microinjection into the cingulate cortex of the rat.}, url = {https://m2.mtmt.hu/api/publication/3228021}, author = {László, Bettina Réka and Hormay, Edina and Szabó, István and Takács, Gábor and Nagy, Bernadett and László, Kristóf and Karádi, Zoltán György}, doi = {10.1016/j.bbr.2017.05.041}, journal-iso = {BEHAV BRAIN RES}, journal = {BEHAVIOURAL BRAIN RESEARCH}, volume = {331}, unique-id = {3228021}, issn = {0166-4328}, abstract = {In order to elucidate whether cytokine mechanisms of the cingulate cortex (cctx) are important in the central regulation of homeostasis, in the present study, feeding-metabolic effects of direct bilateral microinjection of interleukin-1beta (IL-1beta) into the cctx of the rat have been investigated. Short- (2h), medium (12h) and long-term (24h) food and water intakes and body temperature were measured after the intracerebral administration of this primary cytokine or vehicle solution, with or without paracetamol pretreatment. The effect of IL-1beta on the blood glucose level of animals was examined in glucose tolerance test (GTT), and concentrations of relevant plasma metabolites (total cholesterol, HDL, LDH, triglycerides, uric acid) were additionally also determined following the above microinjections. In contrast to causing no major alteration in the food and water intakes, the cytokine treatment evoked significant increase in the body temperature of the rats. Prostaglandin-mediated mechanisms were shown to have important role in the mode of this action of IL-1beta, since paracetamol pretreatment partially prevented the development of the above mentioned hyperthermia. In the GTT, no considerable difference was observed between the blood glucose levels of the cytokine treated and control animals. Following IL-1beta microinjection, however, significant decrease of HDL and total cholesterol was found. Our present findings indicate that elucidating the IL-1beta mediated homeostatic control mechanisms in the cingulate cortex may lead to the better understanding not only the regulatory entities of the healthy organism but also those found in obesity, diabetes mellitus and other worldwide rapidly spreading feeding-metabolic disorders.}, year = {2017}, eissn = {1872-7549}, pages = {115-122}, orcid-numbers = {Hormay, Edina/0009-0004-0598-5061} } @article{MTMT:3169367, title = {Impaired glucose tolerance after streptozotocin microinjection into the mediodorsal prefrontal cortex of the rat}, url = {https://m2.mtmt.hu/api/publication/3169367}, author = {Nagy, Bernadett and Szabó, István and Takács, Gábor and László, Bettina Réka and Hormay, Edina and Karádi, Zoltán György}, doi = {10.1556/2060.103.2016.4.5}, journal-iso = {PHYSIOL INT}, journal = {PHYSIOLOGY INTERNATIONAL}, volume = {103}, unique-id = {3169367}, issn = {2498-602X}, year = {2016}, eissn = {2677-0164}, pages = {403-412}, orcid-numbers = {Hormay, Edina/0009-0004-0598-5061} } @article{MTMT:3041272, title = {Benchmarking antibiotic use, cost and nosocomial infection prevalence in surgical and neurosurgical wards-limitations of recent methods to risk adjust patient casemix}, url = {https://m2.mtmt.hu/api/publication/3041272}, author = {Takács, Gábor and Ferdinándy, Csilla and Merczel, Sára and Süle, András and Hornyák, Judit and Nyaka, Bernadett and Botz, Lajos}, journal-iso = {EUR J HOSP PHARM SCI PRACT}, journal = {EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE}, volume = {23}, unique-id = {3041272}, issn = {2047-9956}, year = {2016}, eissn = {2047-9964}, pages = {A154} } @CONFERENCE{MTMT:2885890, title = {Az antidepresszáns felhasználásnak tulajdonítható csípőcsonttörés hazai populáció szintű járulékos kockázata és a vonatkozó becsült költségek.}, url = {https://m2.mtmt.hu/api/publication/2885890}, author = {Takács, Gábor and Horváth, László and Botz, Lajos}, booktitle = {Kórházi Gyógyszerészek XX. Kongresszusa}, unique-id = {2885890}, year = {2015} } @article{MTMT:2870766, title = {Population attributable risk of hip fractures in antidepressant users in hungary and estimation of the relevant cost consequences.}, url = {https://m2.mtmt.hu/api/publication/2870766}, author = {Takács, Gábor and L., Horváth and Botz, Lajos}, journal-iso = {EUR J HOSP PHARM SCI PRACT}, journal = {EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE}, volume = {22}, unique-id = {2870766}, issn = {2047-9956}, year = {2015}, eissn = {2047-9964}, pages = {A114} } @article{MTMT:2583054, title = {A hazai antidepresszáns terápiás gyakorlat értékelése SOJA és gyógyszerutilizációs módszerekkel}, url = {https://m2.mtmt.hu/api/publication/2583054}, author = {Takács, Gábor and Janknegt, Robert and Botz, Lajos}, journal-iso = {GYÓGYSZERÉSZET}, journal = {GYÓGYSZERÉSZET}, volume = {58}, unique-id = {2583054}, issn = {0017-6036}, year = {2014}, pages = {S124} } @article{MTMT:2583046, title = {Járóbetegellátásban alkalmazott antibiotikumok a Clostridium difficile okozta megbetegedések hátterében?}, url = {https://m2.mtmt.hu/api/publication/2583046}, author = {Miseta, Ildikó and Takács, Gábor and Lankó, Erzsébet and Somogyi-Végh, Anna and Botz, Lajos}, journal-iso = {GYÓGYSZERÉSZET}, journal = {GYÓGYSZERÉSZET}, volume = {58}, unique-id = {2583046}, issn = {0017-6036}, year = {2014}, pages = {S129}, orcid-numbers = {Somogyi-Végh, Anna/0000-0002-1755-0768} } @book{MTMT:2582939, title = {A gyógyszerterápia bizonyítékokon és gyógyszeradatbázisokon alapuló értékelésének gyakorlata}, url = {https://m2.mtmt.hu/api/publication/2582939}, author = {Botz, Lajos and Fittler, András Tamás and Takács, Gábor and Háber, Ágota}, editor = {Botz, Lajos}, publisher = {PTE}, unique-id = {2582939}, year = {2014}, orcid-numbers = {Fittler, András Tamás/0000-0002-8243-6179} } @article{MTMT:2582913, title = {Identification and evaluation of drug–supplement interactions in Hungarian hospital patients.}, url = {https://m2.mtmt.hu/api/publication/2582913}, author = {Somogyi-Végh, Anna and Lankó, Erzsébet and Fittler, András Tamás and Vida, Róbert György and Miseta, Ildikó and Takács, Gábor and Botz, Lajos}, doi = {10.1007/s11096-014-9923-z}, journal-iso = {INT J CLIN PHARM}, journal = {INTERNATIONAL JOURNAL OF CLINICAL PHARMACY}, volume = {36}, unique-id = {2582913}, issn = {2210-7703}, year = {2014}, eissn = {2210-7711}, pages = {451-459}, orcid-numbers = {Somogyi-Végh, Anna/0000-0002-1755-0768; Fittler, András Tamás/0000-0002-8243-6179; Vida, Róbert György/0000-0003-1176-0251} } @CONFERENCE{MTMT:2445419, title = {Új utakon a szakgyógyszerészképzés.}, url = {https://m2.mtmt.hu/api/publication/2445419}, author = {Fittler, András Tamás and Vida, Róbert György and Miseta, Ildikó and Somogyi-Végh, Anna and Takács, Gábor and Botz, Lajos}, booktitle = {Kórházi Gyógyszerészek XIX. Kongresszusa}, unique-id = {2445419}, year = {2013}, orcid-numbers = {Fittler, András Tamás/0000-0002-8243-6179; Vida, Róbert György/0000-0003-1176-0251; Somogyi-Végh, Anna/0000-0002-1755-0768} }