TY - JOUR AU - Révész, Péter AU - Kopjár, E. AU - Szakács, Zsolt AU - Warta, Vilmos AU - Szántóné Csongor, Alexandra AU - Gerlinger, Imre AU - Szanyi, István TI - Comparing the Quality of Life and Hearing Thresholds Following Stapedectomy Versus Laser Stapedotomy with NiTiBOND Piston JF - JOURNAL OF INTERNATIONAL ADVANCED OTOLOGY J2 - J INT ADV OTOL VL - 20 PY - 2024 IS - 2 SP - 142 EP - 146 PG - 5 SN - 1308-7649 DO - 10.5152/iao.2024.231337 UR - https://m2.mtmt.hu/api/publication/34803973 ID - 34803973 LA - English DB - MTMT ER - TY - JOUR AU - Kovács, Márton AU - Uzsaly, János Gáspár AU - Bodzai, G AU - Pap, István AU - Lippai, Bálint AU - Dergez, Tímea AU - Németh, Adrienn AU - Gerlinger, Imre AU - Szanyi, István AU - Bakó, Péter TI - Efficacy of high dose systemic versus combined (systemic and intratympanic) corticosteroid therapy in idiopathic sudden sensorineural hearing loss : A prospective randomized trial and risk factor analysis JF - AMERICAN JOURNAL OF OTOLARYNGOLOGY J2 - AM J OTOLARYNG VL - 45 PY - 2024 IS - 1 PG - 8 SN - 0196-0709 DO - 10.1016/j.amjoto.2023.104099 UR - https://m2.mtmt.hu/api/publication/34335469 ID - 34335469 N1 - University of Pécs, Medical School, Department of Otorhinolaryngology, Munkácsy M St 2, Pécs, H-7621, Hungary University of Pecs, Szentagothai Research Centre, Ifjusag Str 20, Pécs, H-7624, Hungary University of Pécs, Medical School, Institute of Bioanalysis, Honved St 1, Pécs, H-7624, Hungary Export Date: 20 November 2023 CODEN: AJOTD Correspondence Address: Szanyi, I.; University of Pécs, Munkácsy M St 2, Hungary; email: szanyi.istvan@pte.hu AB - The pathophysiology and the proper treatment of idiopathic sudden sensorineural hearing loss (ISSNHL) are an ongoing subject of debate. Locally or systemic administered corticosteroids are the most accepted drugs of treatment in reference to ISSNHL (idiopathic sudden sensorineural hearing loss), however, no strong evidence nor guidelines regarding their effectiveness yet exists. In our prospective, randomized, controlled trial 78 participants were enrolled. Patients were randomly assigned based on the day of admission to two groups according to treatment: group SS (n = 43) received intravenous systemic methylprednisolone alone, and group CT (n = 35) received intratympanic dexamethasone + systemic methylprednisolone. The primary outcome was to compare the hearing outcomes between the treatment groups based on different, widely accepted categories (Siegel, Kanzaki, modified Siegel and PTA4 gain). In consideration of the secondary outcome, we examined the effect of the various risk factors on the hearing improvement. No differences were detected regarding hearing improvement between the two groups, based on any criteria [Siegel's criteria (p = 0.604); Kanzaki's criteria (p = 0.720); modified Siegel's criteria (p = 0.524) and PTA 4 gain (p = 0.569)]. However, several clinical factors such as vertigo (p = 0.039), or cardiovascular comorbidity (p = 0.02) and the severity of initial hearing loss (p = 0.033) were found to bear a significant impact upon the hearing outcome. To the best of our knowledge, this is the first randomized controlled trial comparing high dose systemic and combination corticosteroid therapy in ISSNHL patients. Our findings suggest coexisting cardiovascular comorbidity, vertigo and severity of the initial hearing loss may bear a significantly higher impact upon hearing improvement, than the additional intratympanic steroid administration. The presented trial was registered in the European Union Drug Regulating Authorities Clinical Trials Database (name: Combinated systemic and intratympanic steroid therapy in idiopathic sudden sensorineural hearing loss, No.: 2017-000658-20) and with the ethical approval of The National Institute of Pharmacy and Nutrition (OGYÉI) (protocol No.: 7621, on 2017.02.16.). LA - English DB - MTMT ER - TY - JOUR AU - Tóth, Tamás Ferenc AU - Németh, Adrienn AU - Bakó, Péter AU - Révész, Péter AU - Gerlinger, Imre AU - Szanyi, István TI - Matching the pitch perception of the cochlear implanted ear with the contralateral ear in patients with single-sided deafness: a novel approach JF - EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY J2 - EUR ARCH OTO-RHINO-L VL - 280 PY - 2023 IS - 11 SP - 4851 EP - 4859 PG - 9 SN - 0937-4477 DO - 10.1007/s00405-023-08002-z UR - https://m2.mtmt.hu/api/publication/33806009 ID - 33806009 LA - English DB - MTMT ER - TY - JOUR AU - Pap, István AU - Kovács, Márton AU - Bölcsföldi, Barbara AU - Szakács, Zsolt AU - Gerlinger, Imre AU - Imreh, Bence AU - Szántóné Csongor, Alexandra AU - Warta, Vilmos AU - Szanyi, István TI - Quality-of-life outcomes with endoscopic and microscopic type I tympanoplasty-a prospective cohort study JF - EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY J2 - EUR ARCH OTO-RHINO-L VL - 280 PY - 2023 IS - 10 SP - 4401 EP - 4408 PG - 8 SN - 0937-4477 DO - 10.1007/s00405-023-07938-6 UR - https://m2.mtmt.hu/api/publication/33728524 ID - 33728524 N1 - Department of Otorhinolaryngology, Head and Neck Surgery (ENT), Medical School, University of Pécs, Munkácsy M. Street, No. 2, Pécs, 7621, Hungary Department of Languages for Biomedical Purposes and Communication, Medical School, University of Pécs, Pécs, Hungary First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary Kanizsai Dorottya County Hospital, Nagykanizsa, Hungary Export Date: 29 January 2024 CODEN: EAOTE Correspondence Address: Pap, I.; Department of Otorhinolaryngology, Munkácsy M. Street, No. 2, Hungary; email: pap.istvan@pte.hu AB - Endoscopic type I tympanoplasty was originally introduced in the 1990s and the extensive spread of this practice can be easily observed. The conventional technique performed involves the repair of a tympanic membrane perforation and is defined as microscopic type I tympanoplasty. The aim of this study is the comparison of quality-of-life (QoL) outcomes with endoscopic to that with microscopic type I tympanoplasty.All patients, or in the case of children with the aid of a parent, were asked to complete a novel QoL questionnaire drafted by our study group. The analysis was performed with descriptive statistics-mean, SD and relative frequency-and with a mixed model (generalized least squares fit). A two-sided p value of < 0.05 was regarded as statistically significant.A total of 83 patients completed the questionnaire, 38 in the endoscopic group and 45 in the microscopic group. Every question represented a different. A statistically significant result was found in favor of the endoscopic approach regarding average hospitalization rate (p = 0.003) and cosmetic outcomes (p = 0.015). No statistically significant difference was otherwise observed between the groups.Based on our prospective cohort study, the QoL outcomes of endoscopic type I tympanoplasty in terms of postoperative pain, headache, nausea, vomiting, dizziness, taste disorder and hearing were comparable to the microscopic type I tympanoplasty. In regard to cosmetics, an increase in desirable results was achieved in the endoscopic group, particularly the average hospitalization rate proved to be statistically significantly lower than in the microscopic group. LA - English DB - MTMT ER - TY - JOUR AU - Jakab-Péter, Kinga AU - Háromi, István AU - Kaszás, Bálint AU - Oláh, Zsanett AU - Szanyi, István AU - Somogyvári, Krisztina TI - Rosszindulatúan elfajult nyaki branchiogen cysta JF - ORVOSI HETILAP J2 - ORV HETIL VL - 164 PY - 2023 IS - 10 SP - 388 EP - 392 PG - 5 SN - 0030-6002 DO - 10.1556/650.2023.32741 UR - https://m2.mtmt.hu/api/publication/33706192 ID - 33706192 AB - Branchial cleft cyst is the most common birth defect involving the neck. Malignant transformation is known, however, differentiating from a neck metastasis of a squamous cell carcinoma of unknown primary is challenging. Even though there are strict criterias, the diagnosis of this entity remains controversial. We present the case of a 69-year-old woman, who presented with a swelling under the left side of the mandible. After diagnostic workup, fine-needle aspiration biopsy raised the suspicion of a cystic squamous cell carcinoma metastasis, therefore we performed panendoscopy and modified radical neck dissection. The pathological examination confirmed branchial cleft cyst carcinoma. After surgery, the patient received adjuvant radiation and chemotherapy. During the case workup, we present the difficulties of the diagnostic process, differential diagnostic problems, and the review of the international literature. In the case of a solitary, cystic mass on the neck without a primary tumor, we should consider the possibility of a branchiogenic carcinoma. Orv Hetil. 2023; 164(10): 388-392. LA - Hungarian DB - MTMT ER - TY - JOUR AU - Szabó, Éva AU - Molnár, Krisztián AU - Kovács, Márton AU - Németh, Adrienn AU - Beke, Zsolt AU - Gerlinger, Imre AU - Szanyi, István AU - Bakó, Péter TI - Tág aquaeductus vestibuli okozta harmadikablak-szindróma komplex sebészeti ellátása JF - FÜL-ORR-GÉGEGYÓGYÁSZAT J2 - FÜL-ORR-GÉGEGYÓGYÁSZAT VL - 68 PY - 2022 IS - 4 SP - 153 EP - 155 PG - 3 SN - 0016-237X UR - https://m2.mtmt.hu/api/publication/33255083 ID - 33255083 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Gerlinger, Imre AU - Bakó, Péter AU - Németh, Adrienn AU - Szanyi, István AU - Perényi, Ádám AU - Horváth, Bence AU - Rovó, László TI - III. típusú inkomplett partíció - a cochlea ritka fejlődési rendellenessége, amely komoly kihívás a cochlearis implantációt végzőknek JF - FÜL-ORR-GÉGEGYÓGYÁSZAT J2 - FÜL-ORR-GÉGEGYÓGYÁSZAT VL - 68 PY - 2022 IS - 4 SP - 147 EP - 152 PG - 6 SN - 0016-237X UR - https://m2.mtmt.hu/api/publication/33255050 ID - 33255050 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Harmat, Kinga AU - Tamás, T. László AU - Michael, C. Schubert AU - Szanyi, István AU - Gerlinger, Imre AU - Komoly, Sámuel AU - Büki, Béla TI - A térbeli szemlélet szerepe az otoneurológiában JF - FÜL-ORR-GÉGEGYÓGYÁSZAT J2 - FÜL-ORR-GÉGEGYÓGYÁSZAT VL - 68 PY - 2022 IS - 4 SP - 141 EP - 146 PG - 6 SN - 0016-237X UR - https://m2.mtmt.hu/api/publication/33255034 ID - 33255034 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Bakó, Péter AU - Kovács, Márton AU - Uzsaly, János Gáspár AU - Burián, András AU - Bodzai, Greta AU - Németh, Adrienn AU - Tóth, Arnold AU - Szanyi, István AU - Gerlinger, Imre TI - Subtotal Petrosectomy and Cochlear Implantation in Children With Chronic Suppurative Otitis Media: A Single Institutional Experience JF - Journal of Audiology and Otology J2 - Journal of Audiology and Otology VL - 26 PY - 2022 IS - 4 SP - 214 EP - 222 PG - 9 SN - 2384-1621 DO - 10.7874/jao.2022.00220 UR - https://m2.mtmt.hu/api/publication/33202705 ID - 33202705 AB - Chronic suppurative otitis media (CSOM) with or without cholesteatoma is a frequent chronic inflammatory condition in children, which may lead to severe hearing loss that affects speech development. Treatment of recurrent CSOM associated with unserviceable hearing requires a specialized approach with regard to disease eradication and hearing rehabilitation. In this study, we investigated the advantages of subtotal petrosectomy (SP) combined with cochlear implantation (CI) in children with CSOM associated with unserviceable hearing and describe our experience with regard to the efficacy of this method, together with a literature review.SP with sequential or simultaneous CI was performed in three children (four ears), and postoperative audiometric data were recorded.The study included two male and one female patient. Mean age at the time of SP was 10.75 years (7-13 years). Sequential implantation was performed in three ears. Facial nerve palsy occurred after SP in one patient. The latest word recognition scores of Cases 1, 2, and 3 were 80% (at 60 dB), 75% (at 60 dB), and 70% (at 50 dB) and 90% (at 50 dB), respectively.SP with CI may be safe and reliable in children with CSOM associated with unserviceable hearing. LA - English DB - MTMT ER - TY - JOUR AU - Bölcsföldi, T Barbara AU - Pap, István AU - Tóth, Tamás Ferenc AU - Tóth, István AU - Révész, Péter AU - Gerlinger, Imre AU - Szanyi, István TI - A szelektív epitympanalis dysventilatiós szindróma műtéti megoldása. JF - ORVOSI HETILAP J2 - ORV HETIL VL - 163 PY - 2022 IS - 36 SP - 1440 EP - 1446 PG - 7 SN - 0030-6002 DO - 10.1556/650.2022.32563 UR - https://m2.mtmt.hu/api/publication/33079688 ID - 33079688 N1 - Case Reports AB - The selective epitympanic dysventilation syndrome is a new theory of the cholesteatoma formation, the description of which was allowed by a minimally invasive surgical technique - the transcanal endoscopic ear surgery - some years ago. The transcanal endoscopic ear surgery provided the possibility of a certain amount of detailed anatomical knowledge to identify the new factor behind this process, namely obstruction of the ventilation pathways of the middle ear. Our goal was to draw the ear surgeons' attention to this clinical picture as cholesteatoma development and subsequent worsening of the quality of life caused by ear discharge and conductive hearing loss may be reversible or preventable. We make the syndrome more understandable by using our own anatomical drawings. In this paper, the authors present a case of selective epitympanic dysventilation syndrome, and emphasize the importance of recognition and the endoscopic ear surgical treatment as well as review the international literature. Orv Hetil. 2022; 163(36): 1440-1446. LA - Hungarian DB - MTMT ER -