@article{MTMT:32290011, title = {Ischemic stroke mimics: A comprehensive review}, url = {https://m2.mtmt.hu/api/publication/32290011}, author = {Pohl, Marietta and Hesszenberger, Dávid and Kapus, Krisztián and Meszaros, J. and Feher, A. and Varadi, I. and Pusch, Gabriella and Fejes, E. and Tibold, Antal and Fehér, Gergely}, doi = {10.1016/j.jocn.2021.09.025}, journal-iso = {J CLIN NEUROSCI}, journal = {JOURNAL OF CLINICAL NEUROSCIENCE}, volume = {93}, unique-id = {32290011}, issn = {0967-5868}, year = {2021}, eissn = {1532-2653}, pages = {174-182} } @article{MTMT:31906164, title = {Neuropathic Low Back Pain and Burnout among Hungarian Workers}, url = {https://m2.mtmt.hu/api/publication/31906164}, author = {Mák, Kornél and Kapus, Krisztián and Tóth, Gábor and Hesszenberger, Dávid and Pohl, Marietta and Pusch, Gabriella and Fejes, Éva and Fehér, Gergely and Tibold, Antal}, doi = {10.3390/ijerph18052693}, journal-iso = {INT J ENV RES PUB HE}, journal = {INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH}, volume = {18}, unique-id = {31906164}, issn = {1661-7827}, year = {2021}, eissn = {1660-4601} } @article{MTMT:31840331, title = {MicroRnas in Ischemic Stroke: From Animal Studies to Preclinical Research}, url = {https://m2.mtmt.hu/api/publication/31840331}, author = {Kiss, Gabor and Fehér, Gergely and Hesszenberger, Dávid and Koltai, Katalin and Pusch, Gabriella and Tibold, Antal}, doi = {10.17554/j.issn.2309-6861.2021.08.188}, journal-iso = {J CARDIOL THER}, journal = {JOURNAL OF CARDIOLOGY AND THERAPY}, volume = {8}, unique-id = {31840331}, issn = {2309-6861}, year = {2021}, eissn = {2312-122X}, pages = {963-970} } @article{MTMT:31815621, title = {Internet Addiction and Burnout in A Single Hospital : Is There Any Association?}, url = {https://m2.mtmt.hu/api/publication/31815621}, author = {Tóth, Gábor and Kapus, Krisztián and Hesszenberger, Dávid and Pohl, Marietta and Kosa, Gabor and Kiss, Julianna and Pusch, Gabriella and Fejes, Éva and Tibold, Antal and Fehér, Gergely}, doi = {10.3390/ijerph18020615}, journal-iso = {INT J ENV RES PUB HE}, journal = {INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH}, volume = {18}, unique-id = {31815621}, issn = {1661-7827}, abstract = {The extensive availability of the internet has led to the recognition of problematic internet use, the so-called Internet Addiction (IA), mostly involving adolescents. Burnout can lead to substance abuse or addictive behaviour (such as internet addiction) as a coping method. There are insufficient data about internet addiction and its possible association with burnout in adults, especially among healthcare workers. The aim of our present study was to focus on prevalence and the risk factors of internet addiction and its possible association with burnout among healthcare workers in a single hospital applying a questionnaire-based survey. In total, 49 doctors (10.1%), 198 nurses (40.9%), 123 medical assistant (25.4%), 73 other healthcare workers (15.1%), and 42 (1.7%) healthcare associated workers (cleaning, laundry, etc.) have completed our survey. In a multivariate analysis, IA was associated with age between 18 and 25 (OR: 2.6, p = 0.024), surfing on the internet >5 h daily (OR 25.583, p < 0.001), being single (OR: 4.275, p = 0.006), being childless (OR: 3.81, p = 0.011), working less than five years (OR 2.135, p = 0.048) and job type (being healthcare associated worker, OR: 2.907, p = 0.009). Illicit drug intake (OR 52.494, p < 0.001), and diabetes (OR: 4.122, p = 0.043) were also significantly associated with internet addiction. No association of burnout and IA could be found. A small but significant proportion of our healthcare workers suffered from IA, which was associated with substance abuse and diabetes in multivariate analysis. Our study also draws attention to the risk factors of IA such as younger age, family status, working type and working hours internet use. The possible association of burnout and IA merits further investigation.}, keywords = {hospital; burnout; Internet addiction; healthcare professional}, year = {2021}, eissn = {1660-4601} } @article{MTMT:31690924, title = {Prevalence And Risk Factors Of Internet Addiction Among Hungarian High School Teachers}, url = {https://m2.mtmt.hu/api/publication/31690924}, author = {Tóth, Gábor and Kapus, Krisztián and Hesszenberger, Dávid and Pohl, Marietta and Kosa, Gabor and Kiss, Julianna and Pusch, Gabriella and Fejes, Éva and Tibold, Antal and Fehér, Gergely}, doi = {10.3390/life11030194}, journal-iso = {LIFE-BASEL}, journal = {LIFE-BASEL}, volume = {11}, unique-id = {31690924}, year = {2021}, eissn = {2075-1729} } @article{MTMT:31314094, title = {Associations between serum L-arginine and ficolins in the early phase of acute ischemic stroke – a pilot study}, url = {https://m2.mtmt.hu/api/publication/31314094}, author = {Molnár, Tihamér and Csuka, Dorottya and Pusch, Gabriella and Nagy, Lajos and Garred, Peter and Illés, Zsolt László}, doi = {10.1016/j.jstrokecerebrovasdis.2020.104951}, journal-iso = {J STROKE CEREBROVASC DIS}, journal = {JOURNAL OF STROKE AND CEREBROVASCULAR DISEASES}, volume = {29}, unique-id = {31314094}, issn = {1052-3057}, year = {2020}, eissn = {1532-8511}, orcid-numbers = {Csuka, Dorottya/0000-0003-3610-9852; Illés, Zsolt László/0000-0001-9655-0450} } @article{MTMT:31195387, title = {Framingham Risk Stratification of Middle-Aged Migraineurs}, url = {https://m2.mtmt.hu/api/publication/31195387}, author = {Bank, Gyula Zsolt and Kapus, Krisztián and Meszaros, Janos and Mák, Kornél and Pohl, Marietta and Pusch, Gabriella and Fejes, Éva and Tibold, Antal and Fehér, Gergely}, doi = {10.1155/2020/7351214}, journal-iso = {BEHAV NEUROL}, journal = {BEHAVIOURAL NEUROLOGY}, volume = {2020}, unique-id = {31195387}, issn = {0953-4180}, abstract = {Introduction. Migraine is a common primary headache disorder involving about 10-15% of the whole population. Several epidemiological and prospective studies showed a link between migraine (especially migraine with aura) and cardio- and cerebrovascular events.We prospectively analyzed the data of vascular event-free middle-aged patients with migraine who were referred to our Headache Clinic between 01/2014 and 01/2018. Framingham 10-year risk were calculated; covariates included in the analysis were age, total cholesterol, HDL cholesterol, systolic blood pressure, antihypertensive medication use, current smoking, and diabetes status.Total of 1037 patients were screened and 221 were selected, 161 were women (mean age 55.5 ± 5.2 years) and 60 were men (mean age 56 ± 6 years). 25 patients (11.3%) were labelled as having low risk, 162 patients (73.3%) had moderate risk, and 34 patients (15.4%) had high or very high risk. Blood pressure and lipid targets were reached in 73% and in 49% in the moderate risk and in 53% and 12% in the high risk/very high risk groups, respectively. Migraine with aura (MA) was associated significantly higher cardiovascular risk profile compared with migraine without aura (MO). About one-third of our nondiabetic patients had fasting blood glucose above the normal levels. 24 patients (mean age 60 ± 4.9 years) were diabetic. Mean blood pressure was 149/85 Hgmm, mean choleterol was 5.11 mmol/l, and mean LDL was 2.93 mmol/l in this subgroup, respectively, which do not fall within the recommended targets.Our article draws attention to the higher cardiovascular risk profile of middle-aged migraineurs and highlights the deficiency of primary prevention. Pain physicians must be aware of the cardiovascular aspects of migraine and holistic approach is required instead of focusing only on pain and pain relief.}, year = {2020}, eissn = {1875-8584} } @article{MTMT:31142441, title = {Characteristics of Patients Referred To A Specialized Headache Clinic}, url = {https://m2.mtmt.hu/api/publication/31142441}, author = {Fejes, Éva and Fehér, Gergely and Gurdán, Zsuzsanna and Gombos, Katalin and Koltai, Katalin and Pusch, Gabriella and Tibold, Antal}, doi = {10.1038/s41598-020-58234-w}, journal-iso = {SCI REP}, journal = {SCIENTIFIC REPORTS}, volume = {10}, unique-id = {31142441}, issn = {2045-2322}, abstract = {Headache is a common problem with great effect both on the individual and on the society. Recent studies raised the possibility of increasing rate of specialty referrals, inappropiate treatment and advanced imaging for simple headache. The aim of our study was to analyze the characteritics of patients (including duration of symptoms, headache type, brain imaging, treatment) referred to our specialized headache clinic between 01/01/2014 and 01/01/2015 by their general practitioners and primary care neurologists due to chronic/treatment-resistant headache syndromes. 202 patients (mean age 53.6 ± 17.6 years) were evaluated in our clinic (102 females, mean age 50.14 ± 16.11 years and 100 males, mean age 57 ± 18.1 years). Migraine (84/202) and tension-type (76/202) were the most common syndromes. 202 plain brain CT, 60 contrast-enhanced CT and 128 MRI were carried out by their general practitioners or other healthcare professioners including neurologists before referral to our headache centre. Despite of extensive brain imaging appropiate treatment was started less than 1/3 of all patients and significant proportion received benzodiazepines or opioid therapy. Furthermore, more than 10% of referred patients presented with secondary headache including one meningitis. The management of headache is still a challenge for primary care physicians leading to medical overuse. Vast majority of our patients should not be referred to our specialized headache clinic as they had uncomplicated headache or other underlying conditions than pain.}, year = {2020}, eissn = {2045-2322} } @article{MTMT:30613674, title = {Early seizures after ischemic stroke : focus on thrombolysis}, url = {https://m2.mtmt.hu/api/publication/30613674}, author = {Fehér, Gergely and Gurdán, Zsuzsanna and Gombos, Katalin and Koltai, Katalin and Pusch, Gabriella and Tibold, Antal and Szapáry, László}, doi = {10.1017/S1092852919000804}, journal-iso = {CNS SPECTRUMS}, journal = {CNS SPECTRUMS}, volume = {25}, unique-id = {30613674}, issn = {1092-8529}, abstract = {Stroke is a significant underlying cause of epilepsy. Seizures due to ischemic stroke (IS) are generally categorized into early seizures (ESs) and late seizures (LSs). Seizures in thrombolysis situations may raise the possibility of other etiology than IS.We overtook a systematic review focusing on the pathogenesis, prevalence, risk factors, detection, management, and clinical outcome of ESs in IS and in stroke/thrombolysis situations. We also collected articles focusing on the association of recombinant tissue-type plasminogen activator (rt-PA) treatment and epileptic seizures.We have identified 37 studies with 36,775 participants. ES rate was 3.8% overall in patients with IS with geographical differences. Cortical involvement, severe stroke, hemorrhagic transformation, age (<65 years), large lesion, and atrial fibrillation were the most important risk factors. Sixty-one percent of ESs were partial and 39% were general. Status epilepticus (SE) occurred in 16.3%. 73.6% had an onset within 24 h and 40% may present at the onset of stroke syndrome. Based on EEG findings seizure-like activity could be detected only in approximately 18% of ES patients. MRI diffusion-weighted imaging and multimodal brain imaging may help in the differentiation of ischemia vs. seizure. There are no specific recommendations with regard to the treatment of ES.ESs are rare complications of acute stroke with substantial burden. A significant proportion can be presented at the onset of stroke requiring an extensive diagnostic workup.}, keywords = {thrombolysis; stroke; ischemic stroke; treatment; seizure; Imaging; emergency service}, year = {2020}, eissn = {2165-6509}, pages = {101-113} } @article{MTMT:31278454, title = {Neuropathiás fájdalom: fókuszban az amitriptylin}, url = {https://m2.mtmt.hu/api/publication/31278454}, author = {Fehér, Gergely and Pohl, Marietta and Kapus, Krisztián and Gombos, Katalin and Pusch, Gabriella and Mák, Kornél and Koltai, Katalin and Bank, Gyula Zsolt and Kósa, Gábor and Varjasi, Gábor and Tibold, Antal}, doi = {10.33616/lam.29.046}, journal-iso = {LEGE ART MED}, journal = {LEGE ARTIS MEDICINAE}, volume = {29}, unique-id = {31278454}, issn = {0866-4811}, abstract = {A neuropathiás fájdalom kezelése nagy kihívás elé állítja mind a gyógyítót, mind a beteget. A kórkép kezelésében új szemléletmód szükséges az utóbbi évek neurobiológiai kutatási eredményei alapján. Min­denképpen többszakmás konszenzusokra, munkacsoportokra van szükség (multidisciplinary team) a kórképek sokszínűsége és a konkomittáns pszichopatológia okán. Az eddigi szemléletmód megváltoztatásra szorul, elkerülvén a felesleges diagnosztikus és műtéti beavatkozásokat, melyek a beteg ál­lapotát nem feltétlenül rontják, de pszichés megterhelését mindenképpen fokozzák. A legtöbb bizonyíték a kórkép(ek) gyógy­sze­res kezelésére vonatkozik, az elsőként vá­lasztandó szerek között a triciklusos antidepresszánsok, a szelektív szerotonin-noradrenalin visszavételt gátló szerek és bizonyos antikonvulzív szerek állnak (ga­ba­pentin, pregabalin). Összefoglaló cikkünk célja az egyik legolcsóbb és legszélesebb körben elérhető triciklusos antidepresszáns, az amitriptylin hatékonyságának áttekintése különböző kórképekben.}, keywords = {kezelés; NEUROPATHIA; FÁJDALOM; amitriptylin; triciklusos antidepresszáns}, year = {2019}, eissn = {2063-4161}, pages = {503-510} }