TY - JOUR AU - Geiger, Lili AU - Orsi, Gergely AU - Cseh, Tamás AU - Gombos, Katalin AU - Illés, Zsolt László AU - Czéh, Boldizsár TI - Circulating microRNAs correlate with structural and functional MRI parameters in patients with multiple sclerosis JF - FRONTIERS IN MOLECULAR NEUROSCIENCE J2 - FRONT MOL NEUROSCI VL - 16 PY - 2023 PG - 14 SN - 1662-5099 DO - 10.3389/fnmol.2023.1173212 UR - https://m2.mtmt.hu/api/publication/34198121 ID - 34198121 LA - English DB - MTMT ER - TY - JOUR AU - Gombos, Katalin AU - Gálik, Bence AU - Godony, K. AU - Varnagy, A. AU - Bódis, József AU - Gyenessei, A. AU - Kovács, L. Gábor TI - NGS-based pipeline for routine non-invasive preimplantation genetic assessment in IVF JF - CLINICA CHIMICA ACTA J2 - CLIN CHIM ACTA VL - 530 PY - 2022 SP - S407 EP - S408 PG - 2 SN - 0009-8981 DO - 10.1016/j.cca.2022.04.431 UR - https://m2.mtmt.hu/api/publication/33665711 ID - 33665711 LA - English DB - MTMT ER - TY - JOUR AU - Hamar, Ágoston László AU - Filipánits, Kristóf AU - Váradi, Alex AU - Váradi-Rácz, Rita AU - Gellén, Henrietta Orsolya AU - Futács, Krisztina AU - Urbán, Péter AU - Kovács, L. Gábor AU - Gombos, Katalin TI - Diagnostic accuracy of SARS-CoV-2 Panbio™ rapid antigen diagnostic tests in a 4,440-case clinical follow-up. JF - FRONTIERS IN MEDICINE J2 - FRONT MED VL - 9 PY - 2022 PG - 9 SN - 2296-858X DO - 10.3389/fmed.2022.908127 UR - https://m2.mtmt.hu/api/publication/33061357 ID - 33061357 AB - Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Rapid Antigen Detection Testing (RADT) has been subjected to several evaluations in reference to diagnostic accuracy, ranging from small scale up to large population studies including nation-wide community-based studies. All confirmed the diagnostic accuracy of the tests which were strongly dependent upon the infection's population prevalence. In our retrospective study, parallel SARS-CoV-2 Panbio™ RADT assay, including real-time reverse transcription quantitative polymerase chain reaction (RT-qPCR) tests, were aimed to evaluate diagnostic performance regarding the rapid antigen diagnostic testing. Out of 4,440 paired tests, 609 samples tested positive using RT-qPCR, resulting in a prevalence of 13.7%. Panbio detected 251 (5.7%) positive tested samples. Overall sensitivity was 41.2% (95% CI 37.4-45.2%) and overall specificity was 99.7% (95% CI 99.4-99.8%). Positive predictive value (PPV) was 95.1% (95% CI 91.8-97.1%) and the negative predictive value (NPV) was 91.4% (95% CI 90.5-92.2%). RADT sensitivity increased with stratification in reference to the results according to PCR Cycle threshold (Ct) and presence of the symptoms considerably influenced PPV and NPV. Sensitivity in the group of Ct values ≤ 20 was 91.2%, 68.6% within the Ct range of 20-25, 47.9% in the group of Ct values between 25 and 30, and 12.6% in the group of Ct values between 30 and 35. A follow-up of the positive cases aligned with RT-qPCR testing and comparison of the general population enrolled in the testing in which the fatal cases occurred enabled us to estimate real clinical diagnostic performance regarding the SARS-CoV-2 Panbio RADT. Based upon our results, we recommend the SARS-CoV-2 Panbio RADT tests be carried out as the primary test, without parallel PCR testing, only among high population prevalence rates of the infection and to be used for symptomatic individuals with average or low severe disease developmental risk. In the case of high risk regarding the development of severe infection complications, a parallel SARS-CoV-2 RT-qPCR is needed to be carried out to attain proper diagnostic accuracy and avoid delaying appropriate medical care. LA - English DB - MTMT ER - TY - JOUR AU - Kovács, L. Gábor AU - Gombos, Katalin TI - Novel Molecular Approaches to the Understanding of Pathophysiologal Mechanisms Acting in Human Embryos: An Editorial JF - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES J2 - INT J MOL SCI VL - 23 PY - 2022 IS - 8 PG - 4 SN - 1661-6596 DO - 10.3390/ijms23084327 UR - https://m2.mtmt.hu/api/publication/32785460 ID - 32785460 N1 - Editorial LA - English DB - MTMT ER - TY - GEN AU - Geiger, Lili AU - Horváth, Réka AU - Janszky, József Vladimír AU - Kecskés, Miklós AU - Orsi, Gergely AU - Tóth, Márton AU - Miseta, Attila János AU - Illés, Zsolt László AU - Gombos, Katalin AU - Czéh, Boldizsár TI - Extracellular circulating miRNAs as potential biomarkers in multiple sclerosis and epilepsy PY - 2022 UR - https://m2.mtmt.hu/api/publication/32635269 ID - 32635269 LA - English DB - MTMT ER - TY - CHAP AU - Geiger, Lili AU - Horváth, Réka AU - Kecskés, Miklós AU - Orsi, Gergely AU - M., Tóth AU - Miseta, Attila János AU - Illés, Zsolt László AU - Gombos, Katalin AU - Czéh, Boldizsár ED - Kajos, Luca Fanni ED - Bali, Cintia ED - Preisz, Zsolt ED - Polgár, Petra Ibolya ED - Glázer-Kniesz, Adrienn ED - Tislér, Ádám ED - Szabó, Rebeka TI - Az extracellulárisan keringő miRNS-ek, mint potenciális biomarkerek neuropszichiátriai rendellenességekben: Előzetes tanulmány T2 - 10th Jubilee Interdisciplinary Doctoral Conference : Book of Abstracts = 10. Jubileumi Interdiszciplináris Doktorandusz Konferencia : Absztraktkötet PB - Pécsi Tudományegyetem Doktorandusz Önkormányzat CY - Pécs SN - 9789634298205 PY - 2021 SP - 304 EP - 304 PG - 1 UR - https://m2.mtmt.hu/api/publication/32643372 ID - 32643372 N1 - Poszter LA - Hungarian DB - MTMT ER - TY - CHAP AU - Hamar, Ágoston László AU - Filipánits, Kristóf AU - Glavatity, András AU - Wágner, Róbert AU - Gombos, Katalin ED - Kajos, Luca Fanni ED - Bali, Cintia ED - Preisz, Zsolt ED - Polgár, Petra Ibolya ED - Glázer-Kniesz, Adrienn ED - Tislér, Ádám ED - Szabó, Rebeka TI - Covid-19 pandemic in the Southern Transdanubia region depicted using a dynamic interactive map T2 - 10th Jubilee Interdisciplinary Doctoral Conference : Book of Abstracts = 10. Jubileumi Interdiszciplináris Doktorandusz Konferencia : Absztraktkötet PB - Pécsi Tudományegyetem Doktorandusz Önkormányzat CY - Pécs SN - 9789634298205 PY - 2021 SP - 69 EP - 69 PG - 1 UR - https://m2.mtmt.hu/api/publication/32640021 ID - 32640021 LA - English DB - MTMT ER - TY - JOUR AU - Tod, Pál AU - Borbásné Farkas, Kornélia AU - Németh, Dávid AU - Szénási, Gábor AU - Vincze, Áron AU - Hágendorn, Roland AU - Czakó, László AU - Illés, Dóra AU - Izbéki, Ferenc AU - Dunás-Varga, Veronika AU - Papp, Mária AU - Hamvas, József AU - Varga, Márta AU - Gombos, Katalin AU - Nagy, Tamás AU - Márton, Zsolt AU - Faluhelyi, Nándor AU - Török, Imola AU - Ince, Ali Tüzün AU - Galeev, Shamil AU - Hegyi, Péter Jenő AU - Szentesi, Andrea Ildikó AU - Párniczky, Andrea AU - Szakács, Zsolt AU - Hegyi, Péter AU - Hamar, Péter TI - Initial Renal Function (eGFR) Is a Prognostic Marker of Severe Acute Pancreatitis: A Cohort-Analysis of 1,224 Prospectively Collected Cases JF - FRONTIERS IN MEDICINE J2 - FRONT MED VL - 8 PY - 2021 PG - 10 SN - 2296-858X DO - 10.3389/fmed.2021.671917 UR - https://m2.mtmt.hu/api/publication/32153531 ID - 32153531 N1 - Szentágothai Research Centre, Medical School, Institute for Translational Medicine, University of Pécs, Pécs, Hungary School of Medicine, Institute of Translational Medicine, Semmelweis University, Budapest, Hungary Division of Gastroenterology, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary Department of Medicine, University of Szeged, Szeged, Hungary Szent György University Teaching Hospital of Fejér County, Székesfehérvár, Hungary Division of Gastroenterology, Department of Internal Medicine, University of Debrecen, Debrecen, Hungary Peterfy Hospital, Budapest, Hungary Dr. Réthy Pál Hospital, Békéscsaba, Hungary Department of Laboratory Medicine, Medical School, University of Pécs, Pécs, Hungary Department of Radiology, Medical School, University of Pécs, Pécs, Hungary County Emergency Clinical Hospital - Gastroenterology, University of Medicine, Pharmacy, Sciences and Technology, Târgu Mureṣ, Romania School of Medicine, Hospital of Bezmialem Vakif University, Istanbul, Turkey Saint Luke Clinical Hospital, St. Petersburg, Russian Federation Department of Medicine, Centre for Translational Medicine, University of Szeged, Szeged, Hungary Heim Pál National Pediatric Institute, Budapest, Hungary Centre for Translational Medicine, Medical School, Semmelweis University, Budapest, Hungary Division of Pancreatic Diseases, Heart and Vascular Center, Medical School, Semmelweis University, Budapest, Hungary Cited By :4 Export Date: 26 January 2024 Correspondence Address: Hamar, P.; Szentágothai Research Centre, Hungary; email: hampet@net.sote.hu LA - English DB - MTMT ER - TY - JOUR AU - Bódis, József AU - Szekeres, Júlia AU - Sulyok, Endre AU - Gombos, Katalin AU - Bognár, Zoltán AU - Gyenesei, Attila AU - Gödöny, Krisztina AU - Mauchart, Péter AU - Várnagy, Ákos AU - Ertl, Tibor AU - Nagy, Bernadett AU - Kovács, Kálmán András AU - Kovács, L. Gábor TI - Pécsi innovációs technológiák a humán reprodukció szolgálatában : Embrióvédelemmel kapcsolatos vizsgálatok, hagyományos embriószelekciós eljárások, az embrió életképességének és betegségeinek genetikai markerei JF - NŐGYÓGYÁSZATI ÉS SZÜLÉSZETI TOVÁBBKÉPZŐ SZEMLE J2 - NŐGYÓGYÁSZATI ÉS SZÜLÉSZETI TOVÁBBKÉPZŐ SZEMLE VL - 23 PY - 2021 IS - 3 SP - 72 EP - 86 PG - 15 SN - 1585-8731 UR - https://m2.mtmt.hu/api/publication/32098656 ID - 32098656 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Gombos, Katalin AU - Gálik, Bence AU - Kalács, Krisztina Ildikó AU - Gödöny, Krisztina AU - Várnagy, Ákos AU - Alpár, Donát AU - Bódis, József AU - Gyenesei, Attila AU - Kovács, L. Gábor TI - NGS-Based Application for Routine Non-Invasive Pre-Implantation Genetic Assessment in IVF JF - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES J2 - INT J MOL SCI VL - 22 PY - 2021 IS - 5 PG - 16 SN - 1661-6596 DO - 10.3390/ijms22052443 UR - https://m2.mtmt.hu/api/publication/31895580 ID - 31895580 N1 - * Megosztott szerzőség LA - English DB - MTMT ER -