@misc{MTMT:33335271,
	title = {Altered h-current in cortical interneurons of drug-resistant epileptic patients},
	url = {https://m2.mtmt.hu/api/publication/33335271},
	author = {Tóth, Márton and Szőcs, Szilárd and Henn-Mike, Nóra and Agócs-Laboda, Ágnes and Kovács, Tamás and Dóczi, Tamás Péter and Horváth, Zsolt and Janszky, József Vladimír and Varga, Csaba},
	unique-id = {33335271},
	abstract = {Approximately 30% of the epileptic patients are drug-resistant. Most of this drugresistant group has a well-defined, focal onset region. For these focal onset, drug-resistant epilepsy patients the surgical resection might be the best therapeutic option for achieving seizure freedom. In many cases the pathological high-frequency oscillations (pHFO) are continuously present in the epileptogenic zone (EZ), however, the pHFOs do not always propagate to neighboring areas. The mechanism which blocks this continuously ongoing pHFOs from generating generalized epilepsy is not entirely known. In the present study, we compared the basic electrophysiological properties of GABAergic interneurons of surgically removed EZ and control (non-epileptic, subcortical tumor patient) cortical interneurons. Most GABAergic interneurons in the control cortical preparations showed prominent sag-potentials caused by hcurrent. In contrast, sag-potentials were less prominent or completely missing in epileptic interneurons. H-current in fast-spiker interneurons have been shown previously to be involved in the maintenance of repeated, high-frequency bursting of interneurons. We hypothesize that the epileptic interneurons are unable to maintain high-frequency bursting activity for longer period, which contributes to the propagation and generalization of pHFOs in epilepsy.Our research was funded by TKP20214. The research was performed in collaboration with the Nano-Bio-Imaging core facility at the Szentágothai Research Centre of the University of Pécs.},
	year = {2022},
	orcid-numbers = {Janszky, József Vladimír/0000-0001-6100-832X}
}

@article{MTMT:32893951,
	title = {Epilepsziasebészet a pécsi epilepsziacentrumban},
	url = {https://m2.mtmt.hu/api/publication/32893951},
	author = {Trischlerné Gyimesi, Csilla and Barsi, Péter and Bóné, Beáta and Dóczi, Tamás Péter and Horváth, Réka and Horváth, Zsolt and Komoly, Sámuel and Lőrincz, Katalin Nóra and Tóth, Márton and Janszky, József Vladimír},
	journal-iso = {IDEGGYÓGY SZEMLE PROC},
	journal = {IDEGGYÓGYÁSZATI SZEMLE PROCEEDINGS / CLINICAL NEUROSCIENCE PROCEEDINGS},
	volume = {7},
	unique-id = {32893951},
	issn = {2498-6240},
	year = {2022},
	pages = {17-17},
	orcid-numbers = {Janszky, József Vladimír/0000-0001-6100-832X}
}

@article{MTMT:32893852,
	title = {Fehérállományi neuronok és szerepük a temporalislebeny-epilepsziában},
	url = {https://m2.mtmt.hu/api/publication/32893852},
	author = {Ábrahám, Hajnalka and Sóki, Noémi and Richter, Zsófia and Karádi, Kázmér and Lőrincz, Katalin and Horváth, Réka and Trischlerné Gyimesi, Csilla and Szekeres-Paraczky, Cecília and Sétáló, György (ifj.) and Horváth, Zsolt and Janszky, József Vladimír and Dóczi, Tamás Péter and Seress, László},
	journal-iso = {IDEGGYÓGY SZEMLE PROC},
	journal = {IDEGGYÓGYÁSZATI SZEMLE PROCEEDINGS / CLINICAL NEUROSCIENCE PROCEEDINGS},
	volume = {7},
	unique-id = {32893852},
	issn = {2498-6240},
	year = {2022},
	pages = {8-8},
	orcid-numbers = {Janszky, József Vladimír/0000-0001-6100-832X}
}

@CONFERENCE{MTMT:32643404,
	title = {Altered H-current in cortical interneurons of drug-resistant epileptic patients},
	url = {https://m2.mtmt.hu/api/publication/32643404},
	author = {Tóth, Márton and Szőcs, Szilárd and Henn-Mike, Nóra and Agócs-Laboda, Ágnes and Dóczi, Tamás Péter and Horváth, Zsolt and Janszky, József Vladimír and Varga, Csaba},
	booktitle = {International Neuroscience Meeting, Budapest 2022},
	unique-id = {32643404},
	year = {2022},
	pages = {125},
	orcid-numbers = {Janszky, József Vladimír/0000-0001-6100-832X}
}

@article{MTMT:32598077,
	title = {Investigation of synapses in the cortical white matter in human temporal lobe epilepsy},
	url = {https://m2.mtmt.hu/api/publication/32598077},
	author = {Sóki, Noémi and Richter, Zsófia and Karádi, Kázmér and Lőrincz, Katalin and Horváth, Réka and Trischlerné Gyimesi, Csilla and Szekeres-Paraczky, Cecília Kata and Horváth, Zsolt and Janszky, József Vladimír and Dóczi, Tamás Péter and Seress, László and Ábrahám, Hajnalka},
	doi = {10.1016/j.brainres.2022.147787},
	journal-iso = {BRAIN RES},
	journal = {BRAIN RESEARCH},
	volume = {1779},
	unique-id = {32598077},
	issn = {0006-8993},
	year = {2022},
	eissn = {1872-6240},
	orcid-numbers = {Janszky, József Vladimír/0000-0001-6100-832X}
}

@article{MTMT:32219141,
	title = {The role of hybrid FDG-PET/MRI on decision-making in presurgical evaluation of drug-resistant epilepsy},
	url = {https://m2.mtmt.hu/api/publication/32219141},
	author = {Tóth, Márton and Barsi, Péter and Tóth, Zoltán and Borbély, Katalin and Lückl, János and Emri, Miklós and Repa, Imre and Janszky, József Vladimír and Dóczi, Tamás Péter and Horváth, Zsolt and Halász, Péter and Juhos, Vera and Trischlerné Gyimesi, Csilla and Bóné, Beáta and Kuperczkó, Diána and Horváth, Réka and Nagy, Ferenc and Kelemen, Anna and Jordán, Zsófia and Újvári, Ákos and Hagiwara, Koichi and Isnard, Jean and Pál, Endre and Fekésházy, Attila and Fabó, Dániel and Vajda, Zsolt},
	doi = {10.1186/s12883-021-02352-z},
	journal-iso = {BMC NEUROL},
	journal = {BMC NEUROLOGY},
	volume = {21},
	unique-id = {32219141},
	issn = {1471-2377},
	abstract = {When MRI fails to detect a potentially epileptogenic lesion, the chance of a favorable outcome after epilepsy surgery becomes significantly lower (from 60 to 90% to 20-65%). Hybrid FDG-PET/MRI may provide additional information for identifying the epileptogenic zone. We aimed to investigate the possible effect of the introduction of hybrid FDG-PET/MRI into the algorithm of the decision-making in both lesional and non-lesional drug-resistant epileptic patients.In a prospective study of patients suffering from drug-resistant focal epilepsy, 30 nonlesional and 30 lesional cases with discordant presurgical results were evaluated using hybrid FDG-PET/MRI.The hybrid imaging revealed morphological lesion in 18 patients and glucose hypometabolism in 29 patients within the nonlesional group. In the MRI positive group, 4 patients were found to be nonlesional, and in 9 patients at least one more epileptogenic lesion was discovered, while in another 17 cases the original lesion was confirmed by means of hybrid FDG-PET/MRI. As to the therapeutic decision-making, these results helped to indicate resective surgery instead of intracranial EEG (iEEG) monitoring in 2 cases, to avoid any further invasive diagnostic procedures in 7 patients, and to refer 21 patients for iEEG in the nonlesional group. Hybrid FDG-PET/MRI has also significantly changed the original therapeutic plans in the lesional group. Prior to the hybrid imaging, a resective surgery was considered in 3 patients, and iEEG was planned in 27 patients. However, 3 patients became eligible for resective surgery, 6 patients proved to be inoperable instead of iEEG, and 18 cases remained candidates for iEEG due to the hybrid FDG-PET/MRI. Two patients remained candidates for resective surgery and one patient became not eligible for any further invasive intervention.The results of hybrid FDG-PET/MRI significantly altered the original plans in 19 of 60 cases. The introduction of hybrid FDG-PET/MRI into the presurgical evaluation process had a potential modifying effect on clinical decision-making.Trial registry: Scientific Research Ethics Committee of the Medical Research Council of Hungary.008899/2016/OTIG . Date of registration: 08 February 2016.},
	keywords = {clinical decision-making; epilepsy surgery; Drug-resistant epilepsy; Hybrid FDG-PET/MRI; Preoperative workflow},
	year = {2021},
	eissn = {1471-2377},
	orcid-numbers = {Barsi, Péter/0000-0002-3574-9973; Tóth, Zoltán/0000-0002-8096-3813; Borbély, Katalin/0000-0002-1675-4128; Lückl, János/0000-0001-8094-771X; Janszky, József Vladimír/0000-0001-6100-832X; Kelemen, Anna/0000-0003-3942-3409; Fabó, Dániel/0000-0001-5141-5351}
}

@article{MTMT:31846958,
	title = {Is an Immunosuppressive Microenvironment a Characteristic of Both Intra- and Extraparenchymal Central Nervous Tumors?},
	url = {https://m2.mtmt.hu/api/publication/31846958},
	author = {Soltani, Amina and Kajtár, Béla and Elhusseiny, Mohamed Mahmoud Abdelwahab and Steib, Anita and Horváth, Zsolt and Mangel, László Csaba and Járomi, Luca and Pongrácz, Judit},
	doi = {10.3390/pathophysiology28010004},
	journal-iso = {PATHOPHYSIOLOGY},
	journal = {PATHOPHYSIOLOGY},
	volume = {28},
	unique-id = {31846958},
	issn = {0928-4680},
	year = {2021},
	pages = {34-49},
	orcid-numbers = {Soltani, Amina/0000-0002-4896-4808; Kajtár, Béla/0000-0001-5551-3709; Járomi, Luca/0000-0002-1471-8182; Pongrácz, Judit/0000-0002-0278-5556}
}

@article{MTMT:31602482,
	title = {Etiology-related degree of sprouting of parvalbumin-immunoreactive axons in the human dentate gyrus in temporal lobe epilepsy},
	url = {https://m2.mtmt.hu/api/publication/31602482},
	author = {Ábrahám, Hajnalka and Molnár, Judit E. and Sóki, Noémi and Trischlerné Gyimesi, Csilla and Horváth, Zsolt and Janszky, József Vladimír and Dóczi, Tamás Péter and Seress, László},
	doi = {10.1016/j.neuroscience.2020.09.018},
	journal-iso = {NEUROSCIENCE},
	journal = {NEUROSCIENCE},
	volume = {448},
	unique-id = {31602482},
	issn = {0306-4522},
	year = {2020},
	eissn = {1873-7544},
	pages = {55-70},
	orcid-numbers = {Janszky, József Vladimír/0000-0001-6100-832X}
}

@{MTMT:31016142,
	title = {Központi idegrendszeri daganatok},
	url = {https://m2.mtmt.hu/api/publication/31016142},
	author = {Mangel, László Csaba and Máhr, Károly and Horváth, Zsolt},
	booktitle = {Onkológiai jegyzet},
	unique-id = {31016142},
	year = {2019},
	pages = {141-147}
}

@article{MTMT:30432269,
	title = {Epilepszia sebészeti beavatkozások eredményei a Pécsi Epilepszia Centrumban 2005-2016 között},
	url = {https://m2.mtmt.hu/api/publication/30432269},
	author = {Lőrincz, Katalin Nóra and Bóné, Beáta and Tóth, Márton and Horváth, Réka and Kovács, Norbert and Komoly, Sámuel and Karádi, Kázmér and Barsi, Péter and Ábrahám, Hajnalka and Seress, László and Horváth, Zsolt and Dóczi, Tamás Péter and Janszky, József Vladimír and Trischlerné Gyimesi, Csilla},
	doi = {10.1556/650.2019.31321},
	journal-iso = {ORV HETIL},
	journal = {ORVOSI HETILAP},
	volume = {160},
	unique-id = {30432269},
	issn = {0030-6002},
	abstract = {Epilepsy as a chronic, severe neurologic disease significantly influences the quality of life of the epileptic patients. In candidates well selected for surgery, the seizure freedom is realistically achievable, and the quality of life can be further improved with complex individual rehabilitation.We aimed to evaluate the postoperative outcome of patients who underwent epilepsy surgery between 2005 and 2016 at the Epilepsy Center at Pécs.We evaluated seizure status at regular follow-up visits after surgery and the quality of life using questionnaires focusing on employment and social status.76% of the 72 patients who underwent surgical resection for epilepsy were free from disabling seizures , and 10% had rare disabling seizures (almost seizure-free), 7% experienced worthwhile improvement and 7% had no worthwhile improvement. Comparing the employment status of patients free from disabling seizures to patients not free from disabling seizures, we found that the employment status is significantly influenced by seizure freedom (p<0.01, Fisher's exact test). While 67% of seizure-free patients were employed, only 19% of patients not free from disabling seizures were hired.Our results resemble the international tendencies and success rate, proving epilepsy surgery as an available, valid and effective treatment in well selected patients. Orv Hetil. 2019; 160(7): 270-278.},
	keywords = {Quality of Life; EMPLOYMENT STATUS; életminőség; foglalkoztatottság; epilepsy surgery; epilepsziasebészet; postoperative seizure outcome; posztoperatív rohamkimenetel},
	year = {2019},
	eissn = {1788-6120},
	pages = {270-278},
	orcid-numbers = {Kovács, Norbert/0000-0002-7332-9240; Barsi, Péter/0000-0002-3574-9973; Janszky, József Vladimír/0000-0001-6100-832X}
}