@article{MTMT:33420086,
	title = {Effects of anterior thalamic nucleus DBS on interictal heart rate variability in patients with refractory epilepsy},
	url = {https://m2.mtmt.hu/api/publication/33420086},
	author = {Lőrincz, Katalin and Bóné, Beáta and Karádi, Kázmér and Kis-Jakab, Gréta and Tóth, Natália and Halász, László and Erőss, Loránd and Balás, István and Faludi, Béla and Jordán, Zsófia and Zoltan, Chadaide and Trischlerné Gyimesi, Csilla and Fabó, Dániel and Janszky, József Vladimír},
	doi = {10.1016/j.clinph.2022.11.020},
	journal-iso = {CLIN NEUROPHYSIOL},
	journal = {CLINICAL NEUROPHYSIOLOGY},
	volume = {147},
	unique-id = {33420086},
	issn = {1388-2457},
	year = {2023},
	eissn = {1872-8952},
	pages = {17-30},
	orcid-numbers = {Erőss, Loránd/0000-0002-5796-5546; Fabó, Dániel/0000-0001-5141-5351; Janszky, József Vladimír/0000-0001-6100-832X}
}

@article{MTMT:33117632,
	title = {Multicenter long-term evaluation of safety and efficacy aspects of anterior thalamic deep brain stimulation},
	url = {https://m2.mtmt.hu/api/publication/33117632},
	author = {Kaufmann, E. and Peltola, J. and Colon, A. and Bóné, Beáta and Bentes, C. and Coenen, V. and Gil-Nagel, A. and Goncalves-Ferreira, A. and Lehtimaki, K. and Ryvlin, P. and Taylor, R. and Brionne, T. and Gielen, F. and Song, S. and Boon, P.},
	journal-iso = {EPILEPSIA},
	journal = {EPILEPSIA},
	volume = {63},
	unique-id = {33117632},
	issn = {0013-9580},
	year = {2022},
	eissn = {1528-1167},
	pages = {225-226}
}

@article{MTMT:33106785,
	title = {Increased prevalence of minor physical anomalies in patients with epilepsy – results with the Méhes Scale},
	url = {https://m2.mtmt.hu/api/publication/33106785},
	author = {Tényi, Dalma and Tényi, Tamás and Tényiné Csábi, Györgyi and Bóné, Beáta and Janszky, József Vladimír},
	journal-iso = {EPILEPSIA},
	journal = {EPILEPSIA},
	volume = {63},
	unique-id = {33106785},
	issn = {0013-9580},
	year = {2022},
	eissn = {1528-1167},
	pages = {71-71},
	orcid-numbers = {Janszky, József Vladimír/0000-0001-6100-832X}
}

@article{MTMT:33050343,
	title = {Increased prevalence of minor physical anomalies in patients with epilepsy},
	url = {https://m2.mtmt.hu/api/publication/33050343},
	author = {Tényi, Dalma and Tényi, Tamás and Tényiné Csábi, Györgyi and Jeges, Sára and Bóné, Beáta and Lőrincz, Katalin and Kovács, Norbert and Janszky, József Vladimír},
	doi = {10.1038/s41598-022-17853-1},
	journal-iso = {SCI REP},
	journal = {SCIENTIFIC REPORTS},
	volume = {12},
	unique-id = {33050343},
	issn = {2045-2322},
	abstract = {Our aim was to investigate the rate and topological profile of minor physical anomalies (MPAs) in adult patients with epilepsy with the use of the Méhes Scale, a comprehensive modern scale of dysmorphology. Consecutive epilepsy patients admitted for outpatient evaluation were included. Patients with comorbidities of neurodevelopmental origin (such as autism, severe intellectual disability, attention deficit hyperactivity disorder, schizophrenia, tic disorder, Tourette syndrome, bipolar disorder, specific learning disorder and specific language impairment) were excluded. All participants underwent physical examination with the use of the Méhes Scale for evaluation of MPAs, including 57 minor signs. The frequency and topological profile of MPAs were correlated to clinical patient data using Kruskal–Wallis, chi2 tests and logistic regression model. 235 patients were included, according to the following subgroups: acquired epilepsy (non-genetic, non-developmental etiology) [N = 63], temporal lobe epilepsy with hippocampal sclerosis (TLE with HS) [N = 27], epilepsy with cortical dysgenesis etiology [N = 29], cryptogenic epilepsy [N = 69] and idiopathic generalized epilepsy (IGE) [N = 47]. As controls, 30 healthy adults were recruited. The frequency of MPAs were significantly affected by the type of epilepsy [H(6) = 90.17; p < 0.001]. Pairwise comparisons showed that all patient groups except for acquired epilepsy were associated with increased frequency of MPAs (p < 0.001 in all cases). Furrowed tongue and high arched palate were more common compared to controls in all epilepsy subgroup except for TLE (p < 0.001 or p = 0.001 in all cases). A positive association was detected between the occurrence of MPAs and antiepileptic drug therapy resistance [Exp(B) = 4.19; CI 95% 1.37–12.80; p = 0.012]. MPAs are more common in patients with epilepsy, which corroborates the emerging concept of epilepsy as a neurodevelopmental disorder. Assessment of these signs may contribute to the clarification of the underlying etiology. Moreover, as increased frequency of MPAs may indicate pharmacoresistance, the identification of patients with high number of MPAs could allow evaluation for non-pharmacological treatment in time.},
	year = {2022},
	eissn = {2045-2322},
	orcid-numbers = {Kovács, Norbert/0000-0002-7332-9240; Janszky, József Vladimír/0000-0001-6100-832X}
}

@article{MTMT:33030727,
	title = {Insights from long-term clinical routine use of thalamic deep brain stimulation for epilepsy (MORE)},
	url = {https://m2.mtmt.hu/api/publication/33030727},
	author = {Kaufmann, E. and Peltola, J. and Colon, A. and Bóné, Beáta and Bentes, C. and Coenen, V. and Gil-Nagel, A. and Goncalves-Ferreira, A. and Lehtimaki, K. and Ryvlin, P. and Taylor, R. and Brionne, T. and Gielen, F. and Song, S. and Boon, P.},
	journal-iso = {EUR J NEUROL},
	journal = {EUROPEAN JOURNAL OF NEUROLOGY},
	volume = {29},
	unique-id = {33030727},
	issn = {1351-5101},
	keywords = {Clinical Neurology},
	year = {2022},
	eissn = {1468-1331},
	pages = {264-265}
}

@article{MTMT:32893951,
	title = {Epilepsziasebészet a pécsi epilepsziacentrumban},
	url = {https://m2.mtmt.hu/api/publication/32893951},
	author = {Trischlerné Gyimesi, Csilla and Barsi, Péter and Bóné, Beáta and Dóczi, Tamás Péter and Horváth, Réka and Horváth, Zsolt and Komoly, Sámuel and Lőrincz, Katalin Nóra and Tóth, Márton and Janszky, József Vladimír},
	journal-iso = {IDEGGYÓGY SZEMLE PROC},
	journal = {IDEGGYÓGYÁSZATI SZEMLE PROCEEDINGS / CLINICAL NEUROSCIENCE PROCEEDINGS},
	volume = {7},
	unique-id = {32893951},
	issn = {2498-6240},
	year = {2022},
	pages = {17-17},
	orcid-numbers = {Janszky, József Vladimír/0000-0001-6100-832X}
}

@article{MTMT:32219141,
	title = {The role of hybrid FDG-PET/MRI on decision-making in presurgical evaluation of drug-resistant epilepsy},
	url = {https://m2.mtmt.hu/api/publication/32219141},
	author = {Tóth, Márton and Barsi, Péter and Tóth, Zoltán and Borbély, Katalin and Lückl, János and Emri, Miklós and Repa, Imre and Janszky, József Vladimír and Dóczi, Tamás Péter and Horváth, Zsolt and Halász, Péter and Juhos, Vera and Trischlerné Gyimesi, Csilla and Bóné, Beáta and Kuperczkó, Diána and Horváth, Réka and Nagy, Ferenc and Kelemen, Anna and Jordán, Zsófia and Újvári, Ákos and Hagiwara, Koichi and Isnard, Jean and Pál, Endre and Fekésházy, Attila and Fabó, Dániel and Vajda, Zsolt},
	doi = {10.1186/s12883-021-02352-z},
	journal-iso = {BMC NEUROL},
	journal = {BMC NEUROLOGY},
	volume = {21},
	unique-id = {32219141},
	issn = {1471-2377},
	abstract = {When MRI fails to detect a potentially epileptogenic lesion, the chance of a favorable outcome after epilepsy surgery becomes significantly lower (from 60 to 90% to 20-65%). Hybrid FDG-PET/MRI may provide additional information for identifying the epileptogenic zone. We aimed to investigate the possible effect of the introduction of hybrid FDG-PET/MRI into the algorithm of the decision-making in both lesional and non-lesional drug-resistant epileptic patients.In a prospective study of patients suffering from drug-resistant focal epilepsy, 30 nonlesional and 30 lesional cases with discordant presurgical results were evaluated using hybrid FDG-PET/MRI.The hybrid imaging revealed morphological lesion in 18 patients and glucose hypometabolism in 29 patients within the nonlesional group. In the MRI positive group, 4 patients were found to be nonlesional, and in 9 patients at least one more epileptogenic lesion was discovered, while in another 17 cases the original lesion was confirmed by means of hybrid FDG-PET/MRI. As to the therapeutic decision-making, these results helped to indicate resective surgery instead of intracranial EEG (iEEG) monitoring in 2 cases, to avoid any further invasive diagnostic procedures in 7 patients, and to refer 21 patients for iEEG in the nonlesional group. Hybrid FDG-PET/MRI has also significantly changed the original therapeutic plans in the lesional group. Prior to the hybrid imaging, a resective surgery was considered in 3 patients, and iEEG was planned in 27 patients. However, 3 patients became eligible for resective surgery, 6 patients proved to be inoperable instead of iEEG, and 18 cases remained candidates for iEEG due to the hybrid FDG-PET/MRI. Two patients remained candidates for resective surgery and one patient became not eligible for any further invasive intervention.The results of hybrid FDG-PET/MRI significantly altered the original plans in 19 of 60 cases. The introduction of hybrid FDG-PET/MRI into the presurgical evaluation process had a potential modifying effect on clinical decision-making.Trial registry: Scientific Research Ethics Committee of the Medical Research Council of Hungary.008899/2016/OTIG . Date of registration: 08 February 2016.},
	keywords = {clinical decision-making; epilepsy surgery; Drug-resistant epilepsy; Hybrid FDG-PET/MRI; Preoperative workflow},
	year = {2021},
	eissn = {1471-2377},
	orcid-numbers = {Barsi, Péter/0000-0002-3574-9973; Tóth, Zoltán/0000-0002-8096-3813; Borbély, Katalin/0000-0002-1675-4128; Lückl, János/0000-0001-8094-771X; Janszky, József Vladimír/0000-0001-6100-832X; Kelemen, Anna/0000-0003-3942-3409; Fabó, Dániel/0000-0001-5141-5351}
}

@article{MTMT:32107761,
	title = {Pregnancy and deep brain stimulation therapy for epilepsy},
	url = {https://m2.mtmt.hu/api/publication/32107761},
	author = {Bóné, Beáta and Kovács, Norbert and Balás, István and Horváth, Réka and Dóczi, Tamás Péter and Janszky, József Vladimír},
	doi = {10.1684/epd.2021.1304},
	journal-iso = {EPILEPTIC DISORD},
	journal = {EPILEPTIC DISORDERS},
	volume = {23},
	unique-id = {32107761},
	issn = {1294-9361},
	abstract = {Neuromodulation therapy -vagus nerve stimulation (VNS) and deep brain stimulation (DBS)- is one of the therapeutic options for drug-resistant epilepsy. With the increasing number of DBS implantations in women with epilepsy, it has become a burning issue whether DBS is safe in pregnancy. We report here two women with epilepsy who gave birth to healthy children with DBS therapy. We describe two cases, a 30-year-old woman and a 37-year-old woman. Both were implanted with DBS due to drug-resistant epilepsy. Both of our patients showed a significant improvement after DBS implantation and thereafter gave birth to a healthy child with DBS treatment. The severity and frequency of epileptic seizures did not change during pregnancy and after childbirth. Although a Caesarean section was performed in one case, pregnancies and births were essentially problem-free. At present, the two- and four-year-old children are healthy. Considering these cases, previously described VNS cases, and DBS cases with non-epileptic indications; we suggest that pregnancy and childbirth are safe in epilepsy patients with DBS, moreover, DBS treatment has probably no effect on foetal abnormalities or breastfeeding.},
	keywords = {RISK; EPILEPSY; pregnancy; maternal mortality; Deep brain stimulation; Women of childbearing age; foetal malformations},
	year = {2021},
	eissn = {1950-6945},
	pages = {633-638},
	orcid-numbers = {Kovács, Norbert/0000-0002-7332-9240; Janszky, József Vladimír/0000-0001-6100-832X}
}

@article{MTMT:32070950,
	title = {Toll-Like Receptor Homolog CD180 Expression Is Diminished on Natural Autoantibody-Producing B Cells of Patients with Autoimmune CNS Disorders},
	url = {https://m2.mtmt.hu/api/publication/32070950},
	author = {Hayden, Zsófia and Erdő-Bonyár, Szabina and Bóné, Beáta and Balázs, Noémi and Bodó, Kornélia and Illés, Zsolt László and Berki, Tímea and Simon, Diána},
	doi = {10.1155/2021/9953317},
	journal-iso = {J IMMUNOL RES},
	journal = {JOURNAL OF IMMUNOLOGY RESEARCH},
	volume = {2021},
	unique-id = {32070950},
	issn = {2314-8861},
	abstract = {Decreased expression of TLR homolog CD180 in peripheral blood B cells and its potential role in antibody production have been described in autoimmune diseases. Effectiveness of anti-CD20 therapy in neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) strengthens the role of B cells in the pathogenesis. Therefore, we aimed to investigate the CD180 expression of peripheral blood B cell subsets in NMOSD and MS patients and analyze the levels of natural anti-citrate synthase (CS) IgG autoantibodies and IgG antibodies induced by bacterial infections reported to play a role in the pathogenesis of NMOSD or MS.We analyzed the distribution and CD180 expression of peripheral blood B cell subsets, defined by CD19/CD27/IgD staining, and measured anti-CS IgM/G natural autoantibody and antibacterial IgG serum levels in NMOSD, RRMS, and healthy controls (HC).We found decreased naïve and increased memory B cells in NMOSD compared to MS. Among the investigated four B cell subsets, CD180 expression was exclusively decreased in CD19+CD27+IgD+ nonswitched (NS) memory B cells in both NMOSD and MS compared to HC. Furthermore, the anti-CS IgM natural autoantibody serum level was lower in both NMOSD and MS. In addition, we found a tendency of higher anti-CS IgG natural autoantibody levels only in anti-Chlamydia IgG antibody-positive NMOSD and MS patients.Our results suggest that reduced CD180 expression of NS B cells could contribute to the deficient natural IgM autoantibody production in NMOSD and MS, whereas natural IgG autoantibody levels show an association with antibacterial antibodies.},
	year = {2021},
	eissn = {2314-7156},
	orcid-numbers = {Illés, Zsolt László/0000-0001-9655-0450; Berki, Tímea/0000-0002-0134-8127}
}

@misc{MTMT:32041092,
	title = {Húsz éves a mély agyi stimuláció Pécsett},
	url = {https://m2.mtmt.hu/api/publication/32041092},
	author = {Balás, István and Dóczi, Tamás Péter and Büki, András and Llumiguano Zaruma, Segundo Carlos and Nagy, Máté and Berta, Balázs and Komoly, Sámuel and Janszky, József Vladimír and Aschermann, Zsuzsanna and Deli, Gabriella and Juhász, Annamária and Harmat, Márk and Karádi, Kázmér and Pintér, Dávid and Bóné, Beáta and Kovács, Norbert},
	unique-id = {32041092},
	year = {2021},
	orcid-numbers = {Janszky, József Vladimír/0000-0001-6100-832X; Kovács, Norbert/0000-0002-7332-9240}
}