@article{MTMT:2785400,
	title = {The role of post-translational modifications of microvesicles in systemic immune responses of mice},
	url = {https://m2.mtmt.hu/api/publication/2785400},
	author = {Szabó-Taylor, Katalin and Pálóczi, Krisztina and Szabó, Géza Tamás and Németh, Andrea and Osteikoetxea, Xabier and Sódar, Barbara and Holub Marianna, Csilla and Nyitrayné Pap, Erna and György, Bence and Pállinger, Éva and Szente-Pásztói, Mária and Buzás, Edit Irén},
	journal-iso = {J EXTRACELLULAR VESICL},
	journal = {JOURNAL OF EXTRACELLULAR VESICLES},
	volume = {3},
	unique-id = {2785400},
	year = {2014},
	eissn = {2001-3078},
	pages = {88-88},
	orcid-numbers = {Szabó-Taylor, Katalin/0000-0002-4763-3521; Pálóczi, Krisztina/0000-0001-7065-3582; Szabó, Géza Tamás/0000-0001-9745-6255; Németh, Andrea/0000-0002-0015-8436; Osteikoetxea, Xabier/0000-0003-3628-0174; Sódar, Barbara/0000-0002-8803-7304; Holub Marianna, Csilla/0000-0002-5772-665X; Nyitrayné Pap, Erna/0000-0003-0333-9934; Pállinger, Éva/0000-0002-5789-0951; Buzás, Edit Irén/0000-0002-3744-206X}
}

@article{MTMT:2596795,
	title = {Critical role of extracellular vesicles in modulating the cellular effects of cytokines},
	url = {https://m2.mtmt.hu/api/publication/2596795},
	author = {Szabó, Géza Tamás and Tarr, B and Pálóczi, Krisztina and L. Éder, Katalin and Lajkó, Eszter and Kittel, Ágnes and Tóth, Sára and György, Bence and Szente-Pásztói, Mária and Németh, Andrea and Osteikoetxea, Xabier and Pállinger, Éva and Falus, András and Szabó-Taylor, Katalin and Buzás, Edit Irén},
	doi = {10.1007/s00018-014-1618-z},
	journal-iso = {CELL MOL LIFE SCI},
	journal = {CELLULAR AND MOLECULAR LIFE SCIENCES},
	volume = {71},
	unique-id = {2596795},
	issn = {1420-682X},
	abstract = {Under physiological and pathological conditions, extracellular vesicles (EVs) are present in the extracellular compartment simultaneously with soluble mediators. We hypothesized that cytokine effects may be modulated by EVs, the recently recognized conveyors of intercellular messages. In order to test this hypothesis, human monocyte cells were incubated with CCRF acute lymphoblastic leukemia cell line-derived EVs with or without the addition of recombinant human TNF, and global gene expression changes were analyzed. EVs alone regulated the expression of numerous genes related to inflammation and signaling. In combination, the effects of EVs and TNF were additive, antagonistic, or independent. The differential effects of EVs and TNF or their simultaneous presence were also validated by Taqman assays and ELISA, and by testing different populations of purified EVs. In the case of the paramount chemokine IL-8, we were able to demonstrate a synergistic upregulation by purified EVs and TNF. Our data suggest that neglecting the modulating role of EVs on the effects of soluble mediators may skew experimental results. On the other hand, considering the combined effects of cytokines and EVs may prove therapeutically useful by targeting both compartments at the same time.},
	year = {2014},
	eissn = {1420-9071},
	pages = {4055-4067},
	orcid-numbers = {Szabó, Géza Tamás/0000-0001-9745-6255; Pálóczi, Krisztina/0000-0001-7065-3582; L. Éder, Katalin/0000-0002-3739-423X; Lajkó, Eszter/0000-0002-4796-4646; Tóth, Sára/0000-0001-9852-0458; Németh, Andrea/0000-0002-0015-8436; Osteikoetxea, Xabier/0000-0003-3628-0174; Pállinger, Éva/0000-0002-5789-0951; Falus, András/0000-0002-6843-6789; Szabó-Taylor, Katalin/0000-0002-4763-3521; Buzás, Edit Irén/0000-0002-3744-206X}
}

@article{MTMT:2381023,
	title = {Reduced Inflammatory Threshold Indicates Skin Barrier Defect in Transglutaminase 3 Knockout Mice},
	url = {https://m2.mtmt.hu/api/publication/2381023},
	author = {Bognár, Péter János and Nemeth, I and Mayer, Balázs and Haluszka, Dóra and Wikonkál, Norbert and Ostorházi, Eszter and John, S and Paulsson, M and Smyth, N and Szente-Pásztói, Mária and Buzás, Edit Irén and Szipőcs, Róbert and Kolonics, Attila and Temesvári, Erzsébet and Kárpáti, Sarolta},
	doi = {10.1038/jid.2013.307},
	journal-iso = {J INVEST DERMATOL},
	journal = {JOURNAL OF INVESTIGATIVE DERMATOLOGY},
	volume = {134},
	unique-id = {2381023},
	issn = {0022-202X},
	abstract = {Recently a transglutaminase 3 knockout (TGM3/KO) mouse was generated that showed impaired hair development, but no gross defects in the epidermal barrier, although increased fragility of isolated corneocytes was demonstrated. Here we investigated the functionality of skin barrier in vivo by percutaneous sensitization to fluorescein-isothiocyanate (FITC) in TGM3/KO (n=64) and C57BL/6 WT mice (n=36). Cutaneous inflammation was evaluated by mouse ear swelling test (MEST), histology, serum IgE levels, and by flow-cytometry from draining lymph nodes. Inflammation induced significant MEST difference (P<0.0001) was detected between KO and WT mice and was supported also by histopathology. A significant increase of CD4+ CD25+ activated T-cells (P<0.01) and elevated serum IgE levels (P<0.05) in KO mice indicated more the development of FITC sensibilization than an irritative reaction. P. acnes induced intracutaneous inflammation showed no difference (P=0.2254) between the reactivity of WT and KO immune system. As in vivo tracer, FITC penetration from skin surface followed by two-photon microscopy demonstrated a more invasive percutaneous penetration in KO mice. The clinically uninvolved skin in TGM3/KO mice showed impaired barrier function and higher susceptibility to FITC sensitization indicating that TGM3 has a significant contribution to the functionally intact cutaneous barrier.Journal of Investigative Dermatology accepted article preview online, 24 July 2013. doi:10.1038/jid.2013.307.},
	year = {2014},
	eissn = {1523-1747},
	pages = {105-111},
	orcid-numbers = {Bognár, Péter János/0000-0003-0079-1159; Mayer, Balázs/0000-0003-3577-3823; Haluszka, Dóra/0000-0003-3760-2016; Wikonkál, Norbert/0000-0003-4949-8711; Ostorházi, Eszter/0000-0002-9459-7316; Buzás, Edit Irén/0000-0002-3744-206X; Kolonics, Attila/0000-0003-3990-5336; Temesvári, Erzsébet/0000-0002-6403-5478; Kárpáti, Sarolta/0000-0002-8472-0712}
}

@article{MTMT:2320082,
	title = {The role of citrullination of an immunodominant proteoglycan (PG) aggrecan T cell epitope in BALB/c mice with PG-induced arthritis},
	url = {https://m2.mtmt.hu/api/publication/2320082},
	author = {Misják, Petra and Bősze, Szilvia and Horváti, Kata and Szente-Pásztói, Mária and Pálóczi, Krisztina and Holub Marianna, Csilla and Szakacs, F and Aradi, B and György, Bence and Szabó, Géza Tamás and Nagy, György and Glant, TT and Mikecz, K and Falus, András and Buzás, Edit Irén},
	doi = {10.1016/j.imlet.2013.03.005},
	journal-iso = {IMMUNOL LETT},
	journal = {IMMUNOLOGY LETTERS},
	volume = {152},
	unique-id = {2320082},
	issn = {0165-2478},
	abstract = {The P70-84 peptide (also called 5/4E8 epitope) of the human cartilage proteoglycan (PG) aggrecan is the dominant/arthritogenic epitope in both humans and arthritis-prone BALB/c mice (PG-induced arthritis, PGIA). An elevated T cell reactivity was demonstrated to a citrullinated version of the P70-84 epitope in most of the patients with rheumatoid arthritis (RA). The goal of this study was to understand better how a T cell epitope, if citrullinated, may affect antigenicity/arthritogenicity in PGIA, a murine model of RA. T cell reactivity to differentially citrullinated versions of either the human PG aggrecan P70-84 peptide or the corresponding mouse sequence was assessed in peptide or aggrecan-immunized and arthritic BALB/c mice as well as in T cell receptor transgenic mice specific for peptide P70-84 sequence. Peripheral T cell responses were induced by priming BALB/c mice with either the human wild-type or its citrullinated versions. Unexpectedly, priming with the citrullinated self-peptide induced a higher T cell response compared to the wild-type sequence (p<0.001), and the citrullination of the human peptide abolished T cell reactivity in PGIA. Our data suggest that T cells reactive to the citrullinated P70-84 peptide escaped thymic selection and are present in the peripheral T cell repertoire. Results of this study provide evidence that citrullination of an immunodominant T cell epitope may substantially alter, either increase or abolish, T cell recognition at the periphery in an experimental model of arthritis.},
	year = {2013},
	eissn = {1879-0542},
	pages = {25-31},
	orcid-numbers = {Bősze, Szilvia/0000-0001-9555-699X; Horváti, Kata/0000-0003-4092-6011; Pálóczi, Krisztina/0000-0001-7065-3582; Holub Marianna, Csilla/0000-0002-5772-665X; Szabó, Géza Tamás/0000-0001-9745-6255; Nagy, György/0000-0003-1198-3228; Falus, András/0000-0002-6843-6789; Buzás, Edit Irén/0000-0002-3744-206X}
}

@article{MTMT:2105621,
	title = {The recently identified hexosaminidase D enzyme substantially contributes to the elevated hexosaminidase activity in rheumatoid arthritis},
	url = {https://m2.mtmt.hu/api/publication/2105621},
	author = {Szente-Pásztói, Mária and Sódar, Barbara and Misják, Petra and Pálóczi, Krisztina and Kittel, Ágnes and Tóth, Kálmán and Wellinger, Károly and Géher, Pál and Nagy, György and Lakatos, T and Falus, András and Buzás, Edit Irén},
	doi = {10.1016/j.imlet.2012.10.012},
	journal-iso = {IMMUNOL LETT},
	journal = {IMMUNOLOGY LETTERS},
	volume = {149},
	unique-id = {2105621},
	issn = {0165-2478},
	year = {2013},
	eissn = {1879-0542},
	pages = {71-76},
	orcid-numbers = {Sódar, Barbara/0000-0002-8803-7304; Pálóczi, Krisztina/0000-0001-7065-3582; Géher, Pál/0000-0002-4543-9629; Nagy, György/0000-0003-1198-3228; Falus, András/0000-0002-6843-6789; Buzás, Edit Irén/0000-0002-3744-206X}
}

@article{MTMT:2089636,
	title = {Meta-analysis of exosomal and microvesicular proteoms from the aspect of autoimmunity},
	url = {https://m2.mtmt.hu/api/publication/2089636},
	author = {Szabó, Géza Tamás and Misják, Petra and Aradi, B and György, Bence and Szente-Pásztói, Mária and Pál, Zsuzsanna and László, Valéria and Pállinger, Éva and Nyitrayné Pap, Erna and Kittel, A and Nagy, György and Falus, András and Buzás, Edit Irén},
	journal-iso = {EUR J CLIN INVEST},
	journal = {EUROPEAN JOURNAL OF CLINICAL INVESTIGATION},
	volume = {42},
	unique-id = {2089636},
	issn = {0014-2972},
	year = {2012},
	eissn = {1365-2362},
	pages = {68-68},
	orcid-numbers = {Szabó, Géza Tamás/0000-0001-9745-6255; Pál, Zsuzsanna/0000-0001-6478-9969; Pállinger, Éva/0000-0002-5789-0951; Nyitrayné Pap, Erna/0000-0003-0333-9934; Nagy, György/0000-0003-1198-3228; Falus, András/0000-0002-6843-6789; Buzás, Edit Irén/0000-0002-3744-206X}
}

@article{MTMT:2089619,
	title = {Systematic use of Triton lysis as a control for microvesicle labeling},
	url = {https://m2.mtmt.hu/api/publication/2089619},
	author = {György, Bence and Szente-Pásztói, Mária and Buzás, Edit Irén},
	doi = {10.1182/blood-2012-01-401091},
	journal-iso = {BLOOD},
	journal = {BLOOD},
	volume = {119},
	unique-id = {2089619},
	issn = {0006-4971},
	keywords = {PLASMA; IMMUNOGLOBULIN; priority journal; letter; systemic lupus erythematosus; rheumatoid arthritis; antigen antibody complex; acute coronary syndrome; osteoarthritis; protein aggregation; tyloxapol; chlordane},
	year = {2012},
	eissn = {1528-0020},
	pages = {2175-2176},
	orcid-numbers = {Buzás, Edit Irén/0000-0002-3744-206X}
}

@article{MTMT:2118722,
	title = {Diagnostic assessment of cell-derived microparticles in rheumatoid arthritis is falsified by immune complexes.},
	url = {https://m2.mtmt.hu/api/publication/2118722},
	author = {György, Bence and Módos, Károly and Pállinger, Éva and Pálóczi, Krisztina and Szente-Pásztói, Mária and Misják, Petra and Deli, MA and Sipos, A and Szalai, A and Voszka, István and Polgár, A and Tóth, K and Csete, M and Nagy, György and Gay, S and Falus, András and Kittel, A and Buzás, Edit Irén},
	journal-iso = {ANN RHEUM DIS},
	journal = {ANNALS OF THE RHEUMATIC DISEASES},
	volume = {70},
	unique-id = {2118722},
	issn = {0003-4967},
	year = {2011},
	eissn = {1468-2060},
	pages = {717},
	orcid-numbers = {Módos, Károly/0000-0003-0502-0812; Pállinger, Éva/0000-0002-5789-0951; Pálóczi, Krisztina/0000-0001-7065-3582; Voszka, István/0000-0002-4555-853X; Nagy, György/0000-0003-1198-3228; Falus, András/0000-0002-6843-6789; Buzás, Edit Irén/0000-0002-3744-206X}
}

@article{MTMT:2118082,
	title = {Ízületek autoimmun megbetegedéseinek „édes” (szénhidrát-biológiai) vonatkozásai},
	url = {https://m2.mtmt.hu/api/publication/2118082},
	author = {Szente-Pásztói, Mária and Falus, András and Buzás, Edit Irén},
	journal-iso = {MAGYAR TUDOMÁNY},
	journal = {MAGYAR TUDOMÁNY},
	volume = {172},
	unique-id = {2118082},
	issn = {0025-0325},
	year = {2011},
	eissn = {1588-1245},
	pages = {1346-1354},
	orcid-numbers = {Falus, András/0000-0002-6843-6789; Buzás, Edit Irén/0000-0002-3744-206X}
}

@article{MTMT:2118080,
	title = {Infection and autoimmunity. Lessons of animal models},
	url = {https://m2.mtmt.hu/api/publication/2118080},
	author = {Szente-Pásztói, Mária and Misják, Petra and György, Bence and Aradi, B and Szabó, Géza Tamás and Szántó, B and Holub Marianna, Csilla and Nagy, György and Falus, András and Buzás, Edit Irén},
	doi = {10.1556/EuJMI.1.2011.3.3},
	journal-iso = {EUR J MICROBIOL IMMU},
	journal = {EUROPEAN JOURNAL OF MICROBIOLOGY AND IMMUNOLOGY},
	volume = {1},
	unique-id = {2118080},
	issn = {2062-509X},
	year = {2011},
	eissn = {2062-8633},
	pages = {198-207},
	orcid-numbers = {Szabó, Géza Tamás/0000-0001-9745-6255; Holub Marianna, Csilla/0000-0002-5772-665X; Nagy, György/0000-0003-1198-3228; Falus, András/0000-0002-6843-6789; Buzás, Edit Irén/0000-0002-3744-206X}
}