TY - CHAP AU - Czuppon, György AU - Demény, Attila AU - Leél-Őssy, Szabolcs AU - Stieber, J AU - Óvári, Mihály AU - Dobosy, Péter AU - Berentés, Á AU - Kovács, Richárd ED - Veress, Márton ED - Leél-Őssy, Szabolcs TI - Monitoring and Geochemical Investigations of Caves in Hungary: Implications for Climatological, Hydrological, and Speleothem Formation Processes T2 - Cave and karst systems of Hungary PB - Springer Netherlands CY - Cham SN - 9783030929602 PY - 2022 SP - 465 EP - 486 PG - 22 DO - 10.1007/978-3-030-92960-2_16 UR - https://m2.mtmt.hu/api/publication/33041058 ID - 33041058 LA - English DB - MTMT ER - TY - JOUR AU - Kardos, Julianna AU - Héja, László AU - Simon, Ágnes AU - Jablonkai, István AU - Kovács, Richárd AU - Jemnitz, Katalin TI - Copper signalling: causes and consequences JF - CELL COMMUNICATION AND SIGNALING J2 - CELL COMM SIGN VL - 16 PY - 2018 IS - 1 PG - 21 SN - 1478-811X DO - 10.1186/s12964-018-0277-3 UR - https://m2.mtmt.hu/api/publication/30317831 ID - 30317831 N1 - Journal Article; Review Funding Agency and Grant Number: [KMR_12-1-2012-0112 TRANSRAT]; [VEKOP-2.1.1-15-2016-00156]; [OTKA K124558] Funding text: This work was supported by grants KMR_12-1-2012-0112 TRANSRAT, VEKOP-2.1.1-15-2016-00156 and OTKA K124558. Functional Pharmacology Research Group, Institute of Organic Chemistry, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar Tudósok körútja 2, Budapest, 1117, Hungary Institute of Neurophysiology, Charité-Universitätsmedizin, Berlin, Germany Cited By :28 Export Date: 6 April 2021 Correspondence Address: Kardos, J.; Functional Pharmacology Research Group, Magyar Tudósok körútja 2, Hungary; email: kardos.julianna@ttk.mta.hu Functional Pharmacology Research Group, Institute of Organic Chemistry, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar Tudósok körútja 2, Budapest, 1117, Hungary Institute of Neurophysiology, Charité-Universitätsmedizin, Berlin, Germany Cited By :28 Export Date: 7 April 2021 Correspondence Address: Kardos, J.; Functional Pharmacology Research Group, Magyar Tudósok körútja 2, Hungary; email: kardos.julianna@ttk.mta.hu Functional Pharmacology Research Group, Institute of Organic Chemistry, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar Tudósok körútja 2, Budapest, 1117, Hungary Institute of Neurophysiology, Charité-Universitätsmedizin, Berlin, Germany Cited By :37 Export Date: 29 July 2021 Correspondence Address: Kardos, J.; Functional Pharmacology Research Group, Magyar Tudósok körútja 2, Hungary; email: kardos.julianna@ttk.mta.hu Chemicals/CAS: 4 aminobutyric acid, 28805-76-7, 56-12-2; captopril, 62571-86-2; clioquinol, 130-26-7, 8057-20-3; copper, 15158-11-9, 7440-50-8; disulfiram, 97-77-8; elesclomol, 488832-69-5; glutathione, 70-18-8; metformin, 1115-70-4, 657-24-9; penicillamine, 2219-30-9, 52-67-5; tetrathiomolybdic acid, 13718-35-9, 16330-92-0; trientine, 112-24-3, 38260-01-4; Copper Funding details: Hungarian Scientific Research Fund, OTKA, K124558 Funding text 1: This work was supported by grants KMR_12-1-2012-0112 TRANSRAT, VEKOP-2.1.1-15-2016-00156 and OTKA K124558. AB - Copper-containing enzymes perform fundamental functions by activating dioxygen (O-2) and therefore allowing chemical energy-transfer for aerobic metabolism. The copper-dependence of O-2 transport, metabolism and production of signalling molecules are supported by molecular systems that regulate and preserve tightly-bound static and weakly-bound dynamic cellular copper pools. Disruption of the reducing intracellular environment, characterized by glutathione shortage and ambient Cu(II) abundance drives oxidative stress and interferes with the bidirectional, copper-dependent communication between neurons and astrocytes, eventually leading to various brain disease forms. A deeper understanding of of the regulatory effects of copper on neuro-glia coupling via polyamine metabolism may reveal novel copper signalling functions and new directions for therapeutic intervention in brain disorders associated with aberrant copper metabolism. LA - English DB - MTMT ER - TY - JOUR AU - Kann, O AU - Huchzermeyer, C AU - Kovács, Richárd AU - Wirtz, S AU - Schuelke, M TI - Gamma oscillations in the hippocampus are associated with high oxygen consumption JF - JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM J2 - J CEREBR BLOOD F MET VL - 29 PY - 2009 SP - S388 EP - S389 SN - 0271-678X UR - https://m2.mtmt.hu/api/publication/1760637 ID - 1760637 N1 - SU: Suppl. S1 LA - English DB - MTMT ER - TY - JOUR AU - Szárics, Éva AU - Kovács, Ilona AU - Kovács, Richárd AU - Skuban, N AU - Kardos, Julianna TI - Pyrimidin receptor funkció a központi idegrendszerben JF - ACTA PHARMACEUTICA HUNGARICA J2 - ACTA PHARM HUNG VL - 69 PY - 1999 IS - 5 SP - 227 EP - 231 PG - 5 SN - 0001-6659 UR - https://m2.mtmt.hu/api/publication/1115520 ID - 1115520 N1 - Megjegyzés-21142955 PubMed ID: 10652789 Chemicals/CAS: adenosine triphosphate, 15237-44-2, 56-65-5, 987-65-5; adenosine, 58-61-7; alpha,beta methyleneadenosine triphosphate, 7292-42-4; calcium ion, 14127-61-8; potassium ion, 24203-36-9; sodium ion, 17341-25-2; uridine diphosphate, 58-98-0; uridine, 58-96-8; Purines; Pyrimidines; Receptors, Purinergic Megjegyzés-21143163 PubMed ID: 10652789 Chemicals/CAS: adenosine triphosphate, 15237-44-2, 56-65-5, 987-65-5; adenosine, 58-61-7; alpha,beta methyleneadenosine triphosphate, 7292-42-4; calcium ion, 14127-61-8; potassium ion, 24203-36-9; sodium ion, 17341-25-2; uridine diphosphate, 58-98-0; uridine, 58-96-8; Purines; Pyrimidines; Receptors, Purinergic LA - Hungarian DB - MTMT ER -