TY - JOUR AU - Joó, József Gábor AU - Csatlós, Éva AU - Börzsönyi, Balázs AU - Demendi, Csaba AU - Kornya, László TI - Az oxidatív stressz etiológiai szerepe a főbb szülészeti kórállapotok hátterében JF - MAGYAR NŐORVOSOK LAPJA J2 - MAGYAR NŐORVOSOK LAPJA VL - 86 PY - 2023 IS - 6 SP - 314 EP - 320 PG - 7 SN - 0025-021X UR - https://m2.mtmt.hu/api/publication/34432072 ID - 34432072 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Joó, József Gábor AU - Sulyok, Endre AU - Bódis, József AU - Kornya, László TI - Disrupted Balance of the Oxidant–Antioxidant System in the Pathophysiology of Female Reproduction: Oxidative Stress and Adverse Pregnancy Outcomes JF - CURRENT ISSUES IN MOLECULAR BIOLOGY J2 - CURR ISSUES MOL BIOL VL - 45 PY - 2023 IS - 10 SP - 8091 EP - 8111 PG - 21 SN - 1467-3037 DO - 10.3390/cimb45100511 UR - https://m2.mtmt.hu/api/publication/34196772 ID - 34196772 N1 - ISSN:1467-3045 AB - The significance of oxidative stress in the pathophysiology of male reproductive processes has been closely studied in the last two decades. Recently, it has become clear that oxidative stress can lead to numerous pathological conditions during female reproductive processes as well, contributing to the development of endometriosis, polycystic ovary syndrome and various forms of infertility. During pregnancy, physiological generation of reactive oxygen species (ROS) occurs in association with several developmental processes including oocyte maturation and implantation. An overproduction of ROS can lead to disturbances in fetal development and increases the risk for missed abortion, intrauterine growth restriction, pre-eclampsia, premature delivery and gestational diabetes. Our review focuses on the etiological role of the disrupted oxidant–antioxidant system during human gestation as it relates to adverse pregnancy outcomes. LA - English DB - MTMT ER - TY - JOUR AU - Joó, József Gábor AU - Csatlós, Éva AU - Börzsönyi, Balázs AU - Demendi, Csaba AU - Kornya, László TI - Az oxidatív stressz szerepe a női reprodukcióban JF - MAGYAR NŐORVOSOK LAPJA J2 - MAGYAR NŐORVOSOK LAPJA VL - 86 PY - 2023 IS - 4 SP - 207 EP - 213 PG - 7 SN - 0025-021X UR - https://m2.mtmt.hu/api/publication/34141637 ID - 34141637 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Joó, József Gábor TI - Egyes hiányállapotok jelentőssége és megelőzése, illetve kezelése a háziorvosi gondozás során JF - NŐGYÓGYÁSZATI ÉS SZÜLÉSZETI TOVÁBBKÉPZŐ SZEMLE J2 - NŐGYÓGYÁSZATI ÉS SZÜLÉSZETI TOVÁBBKÉPZŐ SZEMLE VL - 24 PY - 2022 IS - 5 SP - 195 EP - 199 PG - 5 SN - 1585-8731 UR - https://m2.mtmt.hu/api/publication/33915170 ID - 33915170 LA - Hungarian DB - MTMT ER - TY - CHAP AU - Joó, József Gábor AU - Kisfalvi, István ED - Borbola, József TI - Magnézium a szülészet-nőgyógyászati gyakorlatban; prevenció, terápia T2 - Magnéziumpótlás a mindennapi orvosi gyakorlatban PB - Vidal Next Kft. CY - Budapest T3 - Wörwag Házikönyvtár ; 4. PY - 2020 SP - 47 EP - 65 PG - 10 UR - https://m2.mtmt.hu/api/publication/31959841 ID - 31959841 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Kovács, Péter AU - Joó, József Gábor AU - Tamás, Valentina AU - Molnár, Z. AU - Burik-Hajas, Dóra AU - Bódis, József AU - Kornya, László TI - The role of apoptosis in the complex pathogenesis of the most common obstetrics and gynaecology diseases JF - PHYSIOLOGY INTERNATIONAL J2 - PHYSIOL INT VL - 107 PY - 2020 IS - 1 SP - 106 EP - 119 PG - 14 SN - 2498-602X DO - 10.1556/2060.2020.00014 UR - https://m2.mtmt.hu/api/publication/31304588 ID - 31304588 N1 - Clinical Research Units Hungary, Miskolc, Hungary Doctoral School of Health Sciences, Faculty of Health Sciences, University of Pécs, Pécs, Hungary First Department of Obstetrics and Gynaecology, Semmelweis University, Budapest, Hungary Hungarian Academy of Sciences, University of Pécs (MTA-PTE), Human Reproduction Scientific Research Group, University of Pécs, Pécs, Hungary Central Hospital of Southern Pest, National Institute of Hematology and Infectious Diseases, Budapest, Hungary Cited By :3 Export Date: 16 November 2023 Correspondence Address: Joó, J.G.; Clinical Research Units, H-2132 Th€ok€oly str. 15, Hungary; email: joogabor@hotmail.com Chemicals/CAS: protein bcl 2, 219306-68-0; BAX protein, human; bcl-2-Associated X Protein; BCL2 protein, human; Proto-Oncogene Proteins c-bcl-2 LA - English DB - MTMT ER - TY - JOUR AU - Varga, Péter AU - Berecz, Botond AU - Magyar, Zsófia AU - Pete, Barbara AU - Romicsné Görbe, Éva AU - Dombi, Zsófia Anna AU - Sassi, Lilla AU - Fanczal, Eszter AU - Ács, Nándor AU - Kornya, László AU - Joó, József Gábor AU - Valek, Andrea AU - Harmath, Ágnes AU - Gasparics, Ákos TI - Survival and early complications of preterm infants with birthweight less than 500 grams during a 10‐year period in Hungary JF - PAEDIATRIC AND PERINATAL EPIDEMIOLOGY J2 - PAEDIATR PERINAT EP VL - 34 PY - 2020 IS - 5 SP - 565 EP - 571 PG - 7 SN - 0269-5022 DO - 10.1111/ppe.12598 UR - https://m2.mtmt.hu/api/publication/30910717 ID - 30910717 N1 - Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary Central Hospital of South Pest—National Institute of Hematology and Infectology, Department of Obstetrics-Gynecology and Gynecologic Oncology, Budapest, Hungary Heim Pál Children's Hospital, Budapest, Hungary Cited By :1 Export Date: 16 November 2023 CODEN: PPEPE Correspondence Address: Gasparics, Á.; Department of Obstetrics and Gynecology, Hungary; email: gasparics.akos@med.semmelweis-univ.hu Chemicals/CAS: lung surfactant, 99732-49-7; Glucocorticoids; Pulmonary Surfactants Funding text 1: We thank Zsófia Varga for her help in statistical analysis. We also thank data providers contributing to the NICU database. LA - English DB - MTMT ER - TY - JOUR AU - Varga, Péter AU - Berecz, Botond AU - Pete, Barbara AU - Kollár, Tímea AU - Magyar, Zsófia AU - Jeager, Judit AU - Romicsné Görbe, Éva AU - Rigó, János AU - Joó, József Gábor AU - Gasparics, Ákos TI - Trends in Mortality and Morbidity in Infants Under 500 Grams Birthweight: Observations from Our Neonatal Intensive Care Unit (NICU) JF - MEDICAL SCIENCE MONITOR J2 - MED SCI MONIT VL - 24 PY - 2018 SP - 4474 EP - 4480 PG - 7 SN - 1234-1010 DO - 10.12659/MSM.907652 UR - https://m2.mtmt.hu/api/publication/3392001 ID - 3392001 N1 - Cited By :5 Export Date: 25 August 2023 CODEN: MSMOF Correspondence Address: Görbe, É.R.; 1st Department of Obstetrics and Gynecology, Hungary; email: gorbeeva@gmail.com AB - BACKGROUND In our previous study, some changes were presented in obstetric care and we studied the morbidity and mortality trends of infants with <500 grams birth weight. Several neonatal protocol changes occurred during the study period. The aim of this study was to analyze the changes in mortality and morbidity of premature infants in light of changing neonatal protocols. MATERIAL AND METHODS We performed a retrospective study of premature infants with <500 grams birth weight, born at our department between 2006 and 2015. We divided the study period into two 5-year epochs and compared mortality and morbidity rates. We calculated the duration of mechanical ventilation and non-invasive respiratory support, and also investigated the potential impact of the differences in clinical practice. RESULTS The survival rate was 30.8% during first epoch, which was significantly lower than the 70.4% survival rate during second epoch. There was no difference in the rate of complications between the 2 epochs. The total number of ventilator and non-invasive ventilation days was significantly lower in the second epoch. CONCLUSIONS We found significant differences in survival rates but no change in the incidence of morbidities between the 2 epochs. Therefore, although the number of neonates surviving with morbidities has increased, so did the number of those with intact survival. The increased survival of infants born with <500 grams birth weight is not associated with increased rate of morbidities. Protocol changes may have contributed to these findings; however, in a retrospective study it is not possible to separate the impact of individual changes. LA - English DB - MTMT ER - TY - GEN AU - Joó, József Gábor AU - Bódis, J TI - Paradigm shift in the practical education of gynecology PY - 2018 UR - https://m2.mtmt.hu/api/publication/3372401 ID - 3372401 LA - English DB - MTMT ER - TY - GEN AU - Joó, József Gábor TI - Magzati daganatok felismerése és kezelése PY - 2018 UR - https://m2.mtmt.hu/api/publication/3364585 ID - 3364585 LA - Hungarian DB - MTMT ER -