TY - JOUR AU - Rajkai, Csaba AU - Lakatos, Péter AU - Chen, CM AU - Pincze, Zsuzsa AU - Karmos, György AU - Schroeder, CE TI - Transient cortical excitation at the onset of visual fixation JF - CEREBRAL CORTEX J2 - CEREB CORTEX VL - 18 PY - 2008 IS - 1 SP - 200 EP - 209 PG - 10 SN - 1047-3211 DO - 10.1093/cercor/bhm046 UR - https://m2.mtmt.hu/api/publication/1252669 ID - 1252669 N1 - ISI:000251505900020 Megjegyzés-22361420 Z9: 41 WC: Neurosciences AB - Primates actively examine the visual world by rapidly shifting gaze (fixation) over the elements in a scene. Despite this fact, we typically study vision by presenting stimuli with gaze held constant. To better understand the dynamics of natural vision, we examined how the onset of visual fixation affects ongoing neuronal activity in the absence of visual stimulation. We used multiunit activity and current source density measurements to index neuronal firing patterns and underlying synaptic processes in macaque V1. Initial averaging of neural activity synchronized to the onset of fixation suggested that a brief period of cortical excitation follows each fixation. Subsequent single-trial analyses revealed that 1) neuronal oscillation phase transits from random to a highly organized state just after the fixation onset, 2) this phase concentration is accompanied by increased spectral power in several frequency bands, and 3) visual response amplitude is enhanced at the specific oscillatory phase associated with fixation. We hypothesize that nonvisual inputs are used by the brain to increase cortical excitability at fixation onset, thus "priming" the system for new visual inputs generated at fixation. Despite remaining mechanistic questions, it appears that analysis of fixation-related responses may be useful in studying natural vision. LA - English DB - MTMT ER - TY - JOUR AU - Karmos, György AU - Lakatos, Péter AU - Pincze, Zsuzsa AU - Rajkai, Csaba AU - Ulbert, István TI - Intracortical generation and behavioral modulation of auditory cortical gamma activity and steady-state response in the cat JF - INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY J2 - INT J PSYCHOPHYSIOL VL - 54 PY - 2004 IS - 1-2 SP - 74 EP - 75 PG - 2 SN - 0167-8760 DO - 10.1016/j.ijpsycho.2004.05.006 UR - https://m2.mtmt.hu/api/publication/1252674 ID - 1252674 LA - English DB - MTMT ER - TY - JOUR AU - Lakatos, Péter AU - Szilagyi, N AU - Pincze, Zsuzsa AU - Rajkai, Csaba AU - Ulbert, István AU - Karmos, György TI - Attention and arousal related modulation of spontaneous gamma-activity in the auditory cortex of the cat. JF - COGNITIVE BRAIN RESEARCH J2 - COGNITIVE BRAIN RES VL - 19 PY - 2004 IS - 1 SP - 1 EP - 9 PG - 9 SN - 0926-6410 DO - 10.1016/j.cogbrainres.2003.10.023 UR - https://m2.mtmt.hu/api/publication/1121145 ID - 1121145 AB - Sensory information processing in neocortex is associated with rhythmic synchronized gamma frequency firing of sensory cortical units and similar frequency oscillations of the field potentials. Different aspects of the gamma activity (20-80 Hz) have been suggested as correlates of attention, arousal and sensory binding. It is clear that attention has a modality selective influence, while arousal has a more general effect on the sensory systems. We used an experimental conditioning paradigm to separate these differential effects of attention and arousal on spontaneous neocortical gamma activity. We recorded field potentials with epidural electrodes placed above the auditory cortical areas of cats. The animals performed a simple instrumental alimentary conditioning task with different modality (visual and auditory) conditioned stimuli. When they attended to the auditory conditioned stimulus, both frequency and power increase of spontaneous gamma activity were detected. However when they attended visual, we found no power increase of gamma activity recorded above auditory areas, while the frequency increase was the same as in the "attend auditory" condition. We conclude that the power modulation of gamma activity is modality specific and thus can be attributed to selective attention, whereas the frequency modulation of gamma activity shows no modality specificity, it is influenced by the arousal level. LA - English DB - MTMT ER - TY - JOUR AU - Karmos, György AU - Lakatos, Péter AU - Pincze, Zsuzsa AU - Rajkai, Csaba AU - Ulbert, István TI - Behavioral modulation of the auditory steady state response in the cat JF - JOURNAL OF COGNITIVE NEUROSCIENCE J2 - J COGNITIVE NEUROSCI VL - Suppl. 1 PY - 2002 SP - 70 EP - 70 PG - 1 SN - 0898-929X UR - https://m2.mtmt.hu/api/publication/1252679 ID - 1252679 LA - English DB - MTMT ER - TY - JOUR AU - Lakatos, Péter AU - Pincze, Zsuzsa AU - Rajkai, Csaba AU - Ulbert, István AU - Karmos, György TI - Modulation of gamma-activity in the background of an instrumental conditioning paradigm in cats JF - JOURNAL OF COGNITIVE NEUROSCIENCE J2 - J COGNITIVE NEUROSCI VL - Suppl. 1. PY - 2002 SP - 70 EP - 70 PG - 1 SN - 0898-929X UR - https://m2.mtmt.hu/api/publication/1252678 ID - 1252678 LA - English DB - MTMT ER - TY - JOUR AU - Rajkai, Csaba AU - Karmos, György AU - Lakatos, Péter AU - Pincze, Zsuzsa AU - Ulbert, István AU - Javitt, DC TI - Effect of reversible blocade of the medial geniculate body on the auditory cortical ERP in cat JF - JOURNAL OF COGNITIVE NEUROSCIENCE J2 - J COGNITIVE NEUROSCI VL - Suppl. 1. PY - 2002 SP - 40 EP - 40 PG - 1 SN - 0898-929X UR - https://m2.mtmt.hu/api/publication/1252677 ID - 1252677 LA - English DB - MTMT ER - TY - JOUR AU - Karmos, György AU - Lakatos, Péter AU - Pincze, Zsuzsa AU - Rajkai, Csaba AU - Ulbert, István TI - Frequency of gamma activity is modulated by motivation in the auditory cortex of cat. JF - ACTA BIOLOGICA HUNGARICA (1983-2018) J2 - ACTA BIOL HUNG VL - 53 PY - 2002 IS - 4 SP - 473 EP - 483 PG - 11 SN - 0236-5383 DO - 10.1556/ABiol.53.2002.4.8 UR - https://m2.mtmt.hu/api/publication/1121143 ID - 1121143 N1 - Cited By :6 Export Date: 18 November 2019 CODEN: ABHUE Correspondence Address: Karmos, G.; Inst. Psychol. Hungarian Acad. Sci., P.O. Box 398, H-1394 Budapest, Hungary; email: karmos@cogpsyphy.hu AB - Repetitive acoustic stimuli elicit steady-state response (SSR) in the gamma-band both in humans and in mammals. Our aim was to investigate changes of the spontaneous gamma activity and the SSR in the auditory cortex of cats in the background of an instrumental conditioning situation. Epidural electrodes were chronically implanted above the auditory neocortex. The presentation rate of the clicks varied between 20 and 65/s. Spontaneous EEG and SSR were collected in three behavioral states: in an indifferent environment, in the instrumental cage while the cat was waiting for the light CS, and when she stepped on the pedal and was waiting for the meat reward. Using different repetition rate clicks we determined which stimulus rate elicited the largest SSR in these three situations. In quiet animal the highest SSR appeared at 28-30/s. Before and during the CS the optimal stimulus rate shifted to 32-38/s. The frequency of the spontaneous gamma activity changed in parallel way depending on the situation. We conclude that both the SSR and the spontaneous gamma activity reflect resonant activity of the same neuronal circuit of the auditory cortex, and it is modulated by the motivational state of the animal. LA - English DB - MTMT ER - TY - JOUR AU - Pincze, Zsuzsa AU - Lakatos, Péter AU - Rajkai, Csaba AU - Ulbert, István AU - Karmos, György TI - Effect of deviant probability and interstimulus/interdeviant interval on the auditory N1 and mismatch negativity in the cat auditory cortex. JF - COGNITIVE BRAIN RESEARCH J2 - COGNITIVE BRAIN RES VL - 13 PY - 2002 IS - 2 SP - 249 EP - 253 PG - 5 SN - 0926-6410 DO - 10.1016/S0926-6410(01)00105-7 UR - https://m2.mtmt.hu/api/publication/1121142 ID - 1121142 N1 - Cited By :38 Export Date: 18 November 2019 CODEN: CBRRE Correspondence Address: Pincze, Z.; Inst. Psychol. Hungarian Acad. Sci., P.O. Box 398, Budapest, H-1394, Hungary; email: pincze@cogpsyphy.hu AB - In passive oddball paradigm the effects of changes in interstimulus/interdeviant interval (ISI; IDI) and deviant probability were investigated on mismatch negativity (MMN), auditory N1 wave and the exogenous P1 component of the auditory event-related potential in the cat. An epidural electrode matrix was chronically implanted over the auditory fields of the neocortex, and the amplitudes of the aforementioned components were measured in the location of their amplitude maxima. Dependence of the MMN both on the ISI and IDI as well as deviant probability was revealed, while the amplitude of the P1 and N1 showed dependence merely on the ISI. This method can be used for separation of the two negative, often overlapping components in the cat. LA - English DB - MTMT ER - TY - JOUR AU - Karmos, György AU - Lakatos, Péter AU - Pincze, Zsuzsa AU - Rajkai, Csaba AU - Ulbert, István TI - Interaction of auditory ERP and steady-state response in cat:intracortical study JF - INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY J2 - INT J PSYCHOPHYSIOL VL - 41 PY - 2001 IS - 3 SP - 233 EP - 233 PG - 1 SN - 0167-8760 DO - 10.1016/S0167-8760(01)00145-3 UR - https://m2.mtmt.hu/api/publication/1252680 ID - 1252680 N1 - ISI:000169817300129 LA - English DB - MTMT ER - TY - JOUR AU - Pincze, Zsuzsa AU - Lakatos, Péter AU - Rajkai, Csaba AU - Ulbert, István AU - Karmos, György TI - Separation of mismatch negativity and the N1 wave in the auditory cortex of the cat: a topographic study. JF - CLINICAL NEUROPHYSIOLOGY J2 - CLIN NEUROPHYSIOL VL - 112 PY - 2001 IS - 5 SP - 778 EP - 784 PG - 7 SN - 1388-2457 DO - 10.1016/S1388-2457(01)00509-0 UR - https://m2.mtmt.hu/api/publication/1121141 ID - 1121141 N1 - Megjegyzés-22304093 RID: F-2213-2010 Institute for Psychology, Hungarian Academy of Sciences, Budapest, Hungary Institute for Psychology, Hungarian Academy of Sciences, P.O. Box: 398, H-1394 Budapest, Hungary Cited By :68 Export Date: 18 November 2019 CODEN: CNEUF Correspondence Address: Pincze, Z.; Inst. Psychol. Hungarian Acad. Sci., Budapest, Hungary; email: pincze@cogpsyphy.hu AB - OBJECTIVE: The amplitude distribution of the frequency mismatch negativity (MMN) and that of P1 and N1 components were investigated in cats to reveal their sources in the auditory areas of the neocortex. METHODS: Pure tone stimuli were given in a passive oddball paradigm with different degrees of deviance between the standard and deviant tones. Amplitude maps of event-related potential (ERP) components were generated from the responses, recorded in awake, freely moving animals by a chronically implanted epidural electrode matrix, covering both the primary and secondary auditory fields. RESULTS: The P1 and N1 components appeared with highest amplitude on the middle ectosylvian gyrus, while the amplitude maximum of the MMN was ventral and rostral to them on the AII area. Both the latency and the peak amplitude of the MMN depended on the degree of deviance. CONCLUSIONS: The MMN is generated in the rostroventral part of the secondary auditory area, well separated from the sources of the P1 and N1 components. LA - English DB - MTMT ER -