@article{MTMT:34035454, title = {The synthesis of pharmacologically important oxindoles via the asymmetric aldol reaction of isatin and the investigation of the organocatalytic activity of new alicyclic β-amino acid derivatives}, url = {https://m2.mtmt.hu/api/publication/34035454}, author = {Faragó, Tünde and Remete, Attila Márió and Szatmári, István and Ambrus, Rita and Palkó, Márta}, doi = {10.1039/D3RA03528J}, journal-iso = {RSC ADV}, journal = {RSC ADVANCES}, volume = {13}, unique-id = {34035454}, issn = {2046-2069}, abstract = {This work involves the synthesis and subsequent development of a number of novel organocatalysts generated from β-amino acids bearing diendo and diexo norbornene skeletons to improve their catalytic characteristics.}, year = {2023}, eissn = {2046-2069}, pages = {19356-19365}, orcid-numbers = {Faragó, Tünde/0000-0002-3052-8258; Remete, Attila Márió/0000-0001-6388-0197; Szatmári, István/0000-0002-8571-5229; Palkó, Márta/0000-0002-8265-7377} } @article{MTMT:33773728, title = {Angular Regioselective Synthesis of Varied Functionalized Hexahydro-1,2,4-triazolo[4,3-a]quinazolin-9-ones and Their Antiproliferative Action}, url = {https://m2.mtmt.hu/api/publication/33773728}, author = {Said, Awad I. and Gajdács, Márió and Zupkó, István and Haukka, Matti and Palkó, Márta}, doi = {10.3390/molecules28093718}, journal-iso = {MOLECULES}, journal = {MOLECULES}, volume = {28}, unique-id = {33773728}, issn = {1420-3049}, abstract = {New 2-thioxopyrimidin-4-ones capable of participating in regioselective reactions with functionally diverse hydrazonoyl chlorides towards angular regioisomers, rather than linear ones, were designed and synthesized to form stereoisomeric cis- and trans-hexahydro [1,2,4]triazolo[4,3-a]quinazolin-9-ones to be tested as antitumor candidates. The angular regiochemistry of the products was verified through crystallographic experiments and NMR studies. In addition, the regioselectivity of the reaction was found to be independent of the stereochemistry of the used 2-thioxopyrimidin-4-one. Only compound 4c demonstrated satisfactory growth inhibition against all the cancer cells used among all the produced drugs.}, year = {2023}, eissn = {1420-3049}, orcid-numbers = {Said, Awad I./0000-0002-0997-1693; Gajdács, Márió/0000-0003-1270-0365; Zupkó, István/0000-0003-3243-5300; Haukka, Matti/0000-0002-6744-7208; Palkó, Márta/0000-0002-8265-7377} } @CONFERENCE{MTMT:33672957, title = {Green enzymatic strategies for the preparation of enantiomeric carbocyclic beta-amino acid derivatives}, url = {https://m2.mtmt.hu/api/publication/33672957}, author = {Shahmohammadi, Sayeh and Faragó, Tünde and Palkó, Márta and Forró, Enikő}, booktitle = {GreenCat 2022 Book of Abstracts}, unique-id = {33672957}, year = {2022}, orcid-numbers = {Shahmohammadi, Sayeh/0000-0001-7681-5458; Faragó, Tünde/0000-0002-3052-8258; Palkó, Márta/0000-0002-8265-7377; Forró, Enikő/0000-0001-6796-3889} } @article{MTMT:32787510, title = {Green Strategies for the Preparation of Enantiomeric 5–8-Membered Carbocyclic β-Amino Acid Derivatives through CALB-Catalyzed Hydrolysis}, url = {https://m2.mtmt.hu/api/publication/32787510}, author = {Shahmohammadi, Sayeh and Faragó, Tünde and Palkó, Márta and Forró, Enikő}, doi = {10.3390/molecules27082600}, journal-iso = {MOLECULES}, journal = {MOLECULES}, volume = {27}, unique-id = {32787510}, issn = {1420-3049}, year = {2022}, eissn = {1420-3049}, orcid-numbers = {Shahmohammadi, Sayeh/0000-0001-7681-5458; Faragó, Tünde/0000-0002-3052-8258; Palkó, Márta/0000-0002-8265-7377; Forró, Enikő/0000-0001-6796-3889} } @article{MTMT:32533923, title = {Synthesis of Alicyclic 2-Methylenethiazolo[2,3-b]quinazolinone Derivatives via Base-Promoted Cascade Reactions}, url = {https://m2.mtmt.hu/api/publication/32533923}, author = {El Haimer, Mohamed and Faragó, Tünde and Schelz, Zsuzsanna and Zupkó, István and Palkó, Márta}, doi = {10.1055/s-0040-1720028}, journal-iso = {SYNTHESIS-STUTTGART}, journal = {SYNTHESIS-STUTTGART}, volume = {54}, unique-id = {32533923}, issn = {0039-7881}, year = {2022}, eissn = {1437-210X}, pages = {3809-3816}, orcid-numbers = {El Haimer, Mohamed/0000-0003-1155-2874; Faragó, Tünde/0000-0002-3052-8258; Schelz, Zsuzsanna/0000-0002-8519-4830; Zupkó, István/0000-0003-3243-5300; Palkó, Márta/0000-0002-8265-7377} } @article{MTMT:32123857, title = {Novel High Affinity Sigma-1 Receptor Ligands from Minimal Ensemble Docking-Based Virtual Screening}, url = {https://m2.mtmt.hu/api/publication/32123857}, author = {Dvorácskó, Szabolcs and Lázár, László and Fülöp, Ferenc and Palkó, Márta and Zalán, Zita and Penke, Botond and Fülöp, Lívia and Tömböly, Csaba and Bogár, Ferenc}, doi = {10.3390/ijms22158112}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {22}, unique-id = {32123857}, issn = {1661-6596}, year = {2021}, eissn = {1422-0067}, orcid-numbers = {Lázár, László/0000-0002-2135-8496; Fülöp, Ferenc/0000-0003-1066-5287; Palkó, Márta/0000-0002-8265-7377; Zalán, Zita/0000-0002-7146-3024; Penke, Botond/0000-0003-0938-0567; Fülöp, Lívia/0000-0002-8010-0129; Bogár, Ferenc/0000-0002-0611-1452} } @article{MTMT:31860636, title = {Synthesis and biological evaluation of the new ring system benzo[f]pyrimido[1,2-d][1,2,3]triazolo[1,5-a][1,4]diazepine and its cycloalkane and cycloalkene condensed analogues}, url = {https://m2.mtmt.hu/api/publication/31860636}, author = {El Haimer, Mohamed and Palkó, Márta and Matti, Haukka and Gajdács, Márió and Zupkó, István and Fülöp, Ferenc}, doi = {10.1039/D0RA10553H}, journal-iso = {RSC ADV}, journal = {RSC ADVANCES}, volume = {11}, unique-id = {31860636}, issn = {2046-2069}, year = {2021}, eissn = {2046-2069}, pages = {6952-6957}, orcid-numbers = {El Haimer, Mohamed/0000-0003-1155-2874; Palkó, Márta/0000-0002-8265-7377; Gajdács, Márió/0000-0003-1270-0365; Zupkó, István/0000-0003-3243-5300; Fülöp, Ferenc/0000-0003-1066-5287} } @article{MTMT:31817950, title = {Angular Regioselectivity in the Reactions of 2-Thioxopyrimidin-4-ones and Hydrazonoyl Chlorides: Synthesis of Novel Stereoisomeric Octahydro[1,2,4]triazolo[4,3-a]quinazolin-5-ones}, url = {https://m2.mtmt.hu/api/publication/31817950}, author = {Said, Awad I. and Palkó, Márta and Haukka, Matti and Fülöp, Ferenc}, doi = {10.3390/molecules25235673}, journal-iso = {MOLECULES}, journal = {MOLECULES}, volume = {25}, unique-id = {31817950}, issn = {1420-3049}, year = {2020}, eissn = {1420-3049}, orcid-numbers = {Said, Awad I./0000-0002-0997-1693; Palkó, Márta/0000-0002-8265-7377; Haukka, Matti/0000-0002-6744-7208; Fülöp, Ferenc/0000-0003-1066-5287} } @article{MTMT:31648757, title = {Retro Diels Alder protocol for regioselective synthesis of novel [1,2,4]triazolo[4,3- a ]pyrimidin-7(1 H )-ones}, url = {https://m2.mtmt.hu/api/publication/31648757}, author = {Said, Awad I. and Palkó, Márta and Haukka, Matti and Fülöp, Ferenc}, doi = {10.1039/d0ra04345a}, journal-iso = {RSC ADV}, journal = {RSC ADVANCES}, volume = {10}, unique-id = {31648757}, issn = {2046-2069}, year = {2020}, eissn = {2046-2069}, pages = {33937-33943}, orcid-numbers = {Palkó, Márta/0000-0002-8265-7377; Fülöp, Ferenc/0000-0003-1066-5287} } @article{MTMT:30638151, title = {Synthesis of Novel N-Heterocyclic Compounds Containing 1,2,3-Triazole Ring System via Domino, "Click" and RDA Reactions}, url = {https://m2.mtmt.hu/api/publication/30638151}, author = {Palkó, Márta and El Haimer, Mohamed and Kormanyos, Zsanett and Fülöp, Ferenc}, doi = {10.3390/molecules24040772}, journal-iso = {MOLECULES}, journal = {MOLECULES}, volume = {24}, unique-id = {30638151}, issn = {1420-3049}, abstract = {An uncomplicated, high-yielding synthetic route has been developed to constitute complicated heterocycles, applying domino, click and retro-Diels-Alder (RDA) reaction sequences. Starting from 2-aminocarboxamides, a new set of isoindolo[2,1-a]quinazolinones was synthesized with domino ring closure. A click reaction was performed to create the 1,2,3-triazole heterocyclic ring, followed by an RDA reaction resulting in dihydropyrimido[2,1-a]isoindole-2,6-diones. The absolute configuration, concluded by the norbornene structure that served as a chiral source, remained constant throughout the transformations. The structure of the synthesized compounds was examined by H-1 and C-13 Nuclear Magnetic Resonance (NMR) methods.}, keywords = {DERIVATIVES; ACID; SATURATED HETEROCYCLES; Chemistry; DIELS-ALDER REACTION; stereoselectivity; regioselectivity; Click reaction; Biochemistry & Molecular Biology; domino ring closure; RDA reaction}, year = {2019}, eissn = {1420-3049}, orcid-numbers = {Palkó, Márta/0000-0002-8265-7377; El Haimer, Mohamed/0000-0003-1155-2874; Fülöp, Ferenc/0000-0003-1066-5287} }