TY - JOUR AU - Nemes, Attila TI - Left atrial strains in cardiac amyloidosis -does its subtype matter? JF - INTERNATIONAL JOURNAL OF CARDIOLOGY J2 - INT J CARDIOL PY - 2024 SN - 0167-5273 DO - 10.1016/j.ijcard.2024.132078 UR - https://m2.mtmt.hu/api/publication/34803172 ID - 34803172 LA - English DB - MTMT ER - TY - JOUR AU - Nemes, Attila TI - Are there Disease-Specific Functional Features of Cardiac Mechanics? JF - REVIEWS IN CARDIOVASCULAR MEDICINE J2 - REV CARDIOVASC MED VL - 25 PY - 2024 IS - 4 PG - 2 SN - 1530-6550 DO - 10.31083/j.rcm2504137 UR - https://m2.mtmt.hu/api/publication/34788779 ID - 34788779 LA - English DB - MTMT ER - TY - JOUR AU - Nemes, Attila AU - Kormányos, Árpád AU - Orosz, Andrea AU - Ambrus, Nóra AU - Várkonyi, Tamás AU - Lengyel, Csaba Attila TI - Autonomic function and specific right atrial functions - Is there a relationship? Correlations from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study JF - JOURNAL OF CLINICAL ULTRASOUND J2 - J CLIN ULTRASOUND PY - 2024 PG - 8 SN - 0091-2751 DO - 10.1002/jcu.23672 UR - https://m2.mtmt.hu/api/publication/34778284 ID - 34778284 N1 - Department of Medicine, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary Department of Pharmacology and Pharmacotherapy, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary Export Date: 23 April 2024 CODEN: JCULD Correspondence Address: Nemes, A.; Department of Medicine, H-6725 Szeged, emmelweis street 8, P.O. Box 427, Hungary; email: nemes.attila@med.u-szeged.hu AB - Similarly to the ventricles, the atria are under sympathetic/parasympathetic neural regulation. Accordingly, correlations were investigated between Ewing's standard cardiovascular reflex tests (SCRTs) and three-dimensional speckle-tracking echocardiography (3DSTE)-derived right atrial (RA) volumes and strains in healthy subjects.The study comprised 45 healthy adults, but 5 subjects were excluded due to inferior image quality for 3DSTE-derived RA assessments. The remaining 40 individuals being in sinus rhythm had a mean age of 35.1 ± 3.5 years (20 men). Two-dimensional, Doppler, 3DSTE and SCRTs were performed in all cases.RA maximum volume and total and passive RA stroke volumes correlated with the Valsalva ratio. Active RA stroke volume and emptying fraction showed correlations with 30/15 ratio. Peak global and mean segmental RA circumferential (CS) and longitudinal strains (LS) showed correlation with the Valsalva ratio. At atrial contraction, global RA-LS and mean segmental RA-CS showed correlations with the Valsalva ratio. Moreover, mean segmental RA-CS correlated with 30/15 ratio and mean segmental RA radial strain showed correlations with systolic blood pressure in response to standing. Autonomic neuropathy score correlated with peak global RA-LS.Autonomic function parameters have significant associations with specific RA functions in healthy adults, making the latter possible indicators of autonomic dysregulation. LA - English DB - MTMT ER - TY - CHAP AU - Nemes, Attila AU - Rácz, Gergely AU - Kormányos, Árpád AU - Ruzsa, Zoltán AU - Achim, Alexandru AU - Lengyel, Csaba Attila ED - Cristiana, Bustea ED - Delia, Mirela Tit TI - The Relationship between Tricuspid Annular Longitudinal and Sphincter-Like Features of Its Function in Healthy Adults: Insights from the MAGYAR-Healthy Study T2 - Cardiovascular Diseases: From Basic Research to Clinical Application PB - MDPI CY - Basel SN - 9783725806126 PY - 2024 SP - 155 EP - 164 PG - 10 UR - https://m2.mtmt.hu/api/publication/34768899 ID - 34768899 LA - English DB - MTMT ER - TY - JOUR AU - Nemes, Attila TI - Cardiac Mechanics and Valvular and Vascular Abnormalities in Hypereosinophilic Syndrome JF - JOURNAL OF CLINICAL MEDICINE J2 - J CLIN MED VL - 13 PY - 2024 IS - 5 PG - 12 SN - 2077-0383 DO - 10.3390/jcm13051403 UR - https://m2.mtmt.hu/api/publication/34694340 ID - 34694340 AB - Hypereosinophilic syndrome (HES) is considered to be a rare myeloproliferative disease that is characterized by persistent eosinophilia with associated multiple-organ damage. The heart is often involved in HES, representing a major cause of morbidity and mortality. HES is a heterogeneous group of disorders; the majority of the cases are idiopathic. Summarizing the findings regarding myocardial, valvular, and vascular abnormalities in a series of patients with HES, most studies found normal left ventricular (LV) volumes with reduced LV global longitudinal strain and LV apical rotation and twist in HES cases, accompanied by increased left atrial (LA) volumes and stroke volumes, reduced peak LA circumferential strain (representing systolic abnormalities), and mitral annular dilation and functional deterioration. Regarding the right heart, preserved right ventricular volumes and functional properties, increased right atrial volumes, mild RA functional abnormalities, and dilated tricuspid annular dimensions without functional impairment could be seen in these studies. Aortic and pulmonary valves showed no specific disease-related alterations. Vascular abnormalities included increased aortic stiffness without dilation of the aorta and pulmonary hypertension in some cases. These results suggest disease-specific but relatively mild myocardial, valvular, and vascular abnormalities in HES. The present review aimed to summarize the available clinical data about cardiac mechanics and valvular and vascular abnormalities in a series of patients with HES. LA - English DB - MTMT ER - TY - JOUR AU - Nemes, Attila AU - Kormányos, Árpád AU - Ruzsa, Zoltán AU - Achim, Alexandru AU - Ambrus, Nóra AU - Lengyel, Csaba Attila TI - Right Ventricular Longitudinal Shortening is not Associated with Left Ventricular Rotational Mechanics in Healthy Adults - Insights from the Three-dimensional Speckle-tracking Echocardiographic MAGYAR-Healthy Study JF - REVIEWS IN CARDIOVASCULAR MEDICINE J2 - REV CARDIOVASC MED VL - 25 PY - 2024 IS - 2 PG - 9 SN - 1530-6550 DO - 10.31083/j.rcm2502053 UR - https://m2.mtmt.hu/api/publication/34557988 ID - 34557988 N1 - Export Date: 23 April 2024 CODEN: RCMEC Correspondence Address: Nemes, A.; Department of Medicine, Hungary; email: nemes.attila@med.u-szeged.hu LA - English DB - MTMT ER - TY - JOUR AU - Nemes, Attila TI - Myocardial Mechanics and Associated Valvular and Vascular Abnormalities in Left Ventricular Noncompaction Cardiomyopathy JF - JOURNAL OF CLINICAL MEDICINE J2 - J CLIN MED VL - 13 PY - 2024 IS - 1 PG - 20 SN - 2077-0383 DO - 10.3390/jcm13010078 UR - https://m2.mtmt.hu/api/publication/34471600 ID - 34471600 AB - Left ventricular (LV) non-compaction (LVNC) is a rare genetic cardiomyopathy due to abnormal intra-uterine arrest of compaction of the myocardial fibers during endomyocardial embryogenesis. Due to the partial or complete absence of LV compaction, the structure of the LV wall shows characteristic abnormalities, including a thin compacted epicardium and a thick non-compacted endocardium with prominent trabeculations and deep intertrabecular recesses. LVNC is frequently associated with chronic heart failure, life-threatening ventricular arrhythmias, and systemic embolic events. According to recent findings, in the presence of LVNC, dysfunctional LV proved to be associated with left atrial volumetric and functional abnormalities and consequential dilated and functionally impaired mitral annulus, partly explaining the higher prevalence of regurgitation. Although the non-compaction process morphologically affects only the LV, signs of remodeling of the right heart were also detected. Moreover, dilation and stiffening of the aorta were present. The aim of the present detailed review was to summarize findings regarding changes in cardiac mechanics, valvular abnormalities, and vascular remodeling detected in patients with LVNC. LA - English DB - MTMT ER - TY - JOUR AU - Nemes, Attila AU - Kormányos, Árpád AU - Orosz, Andrea AU - Ambrus, Nóra AU - Várkonyi, Tamás AU - Lengyel, Csaba Attila TI - Correlations between vegetative autonomic function and specific left atrial functions in healthy adults: Insights from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study JF - JOURNAL OF CLINICAL ULTRASOUND J2 - J CLIN ULTRASOUND VL - 52 PY - 2024 IS - 2 SP - 178 EP - 185 PG - 8 SN - 0091-2751 DO - 10.1002/jcu.23603 UR - https://m2.mtmt.hu/api/publication/34400260 ID - 34400260 N1 - Department of Medicine, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary Department of Pharmacology and Pharmacotherapy, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary Cited By :2 Export Date: 23 April 2024 CODEN: JCULD Correspondence Address: Nemes, A.; Department of Medicine, Semmelweis Street 8, P.O. Box 427, Hungary; email: nemes.attila@med.u-szeged.hu AB - The functioning of the left atrium (LA) is partly controlled by the neural system. It was purposed to evaluate correlations between the result of Ewing's 5 standard cardiovascular reflex tests (SCRTs) characterizing autonomic function and LA volumetric and functional features as assessed by three-dimensional speckle-tracking echocardiography (3DSTE) in healthy individuals.The current study comprised 18 healthy volunteers being in sinus rhythm (mean age: 35 ± 12 years, 10 men). Measurement of blood pressure, ECG, 5 SCRTs, two-dimensional Doppler echocardiography and 3DSTE were performed. These parameters were in normal ranges in all cases.From LA volumetric parameters, only systolic total atrial emptying fraction (r = 0.559, p = 0.037) and early diastolic passive atrial emptying fraction (r = 0.539, p = 0.047) correlated with systolic blood pressure response to standing representing sympathetic autonomic function. From LA strains, peak mean segmental LA radial strain (RS) (r = -0.532, p = 0.050), global and mean segmental LA circumferential strain (CS) (r = 0.662, p = 0.010 and r = 0.635, p = 0.015, respectively) representing systolic LA function correlated with Valsalva ratio representing parasympathetic autonomic function. Global LA-RS (r = -0.713, p = 0.040) and LA-CS (r = 0.657, p = 0.011) and mean segmental LA-CS (r = 0.723, p = 0.003) at atrial contraction representing end-diastolic atrial contraction showed correlations with Valsalva ratio, as well. Peak global and mean segmental LA-CS (r = 0.532, p = 0.050 and r = 0.530, p = 0.050) and the same strains at atrial contraction (r = 0.704, p = 0.005 and r = 0.690, p = 0.006) representing systolic function and end-diastolic atrial contraction correlated with systolic blood pressure response to standing representing both parasympathetic and sympathetic autonomic functions.Significant correlations between features of vegetative autonomic function represented by Ewing's 5 SCRTs and specific LA functions represented by 3DSTE-derived LA volume-based functional properties and strains could be demonstrated in healthy adults. LA - English DB - MTMT ER - TY - JOUR AU - Christofi, A AU - Kormányos, Árpád AU - Kalapos, Anita AU - Domsik, Péter AU - Gyenes, Nándor AU - Ambrus, Nóra AU - Gavallér, Edit Henriette AU - Csajbók, Éva AU - Julesz, János AU - Forster, Tamás AU - Csanády, Miklós AU - Horváth, Á AU - Lengyel, Csaba Attila AU - Nemes, Attila AU - Valkusz, Zsuzsanna TI - A NÖVEKEDÉSI HORMON HATÁSA A SZÍV FIZIOLÓGIÁJÁRA JF - MAGYAR BELORVOSI ARCHIVUM J2 - MBA VL - 76 PY - 2023 IS - 5-6 SP - 303 EP - 303 PG - 1 SN - 0133-5464 UR - https://m2.mtmt.hu/api/publication/34559525 ID - 34559525 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Vágvölgyi, Anna AU - Nyiraty, Szabolcs AU - Máthéné, Köteless É AU - Korom, A AU - Ábrahám, Erzsébet Judit AU - Barnai, Mária AU - Szűcs, Mónika AU - Orosz, Andrea AU - Nemes, Attila AU - Baczkó, István AU - Kempler, Péter AU - Várkonyi, Tamás AU - Kósa, István AU - Lengyel, Csaba Attila TI - Három hónapos edzésprogram javítja a kardiovaszkuláris autonóm funkciót a metabolikus szindrómás páciensekben JF - MAGYAR BELORVOSI ARCHIVUM J2 - MBA VL - 76 PY - 2023 IS - 5-6 SP - 338 EP - 339 PG - 2 SN - 0133-5464 UR - https://m2.mtmt.hu/api/publication/34519512 ID - 34519512 LA - Hungarian DB - MTMT ER -