@article{MTMT:32123857, title = {Novel High Affinity Sigma-1 Receptor Ligands from Minimal Ensemble Docking-Based Virtual Screening}, url = {https://m2.mtmt.hu/api/publication/32123857}, author = {Dvorácskó, Szabolcs and Lázár, László and Fülöp, Ferenc and Palkó, Márta and Zalán, Zita and Penke, Botond and Fülöp, Lívia and Tömböly, Csaba and Bogár, Ferenc}, doi = {10.3390/ijms22158112}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {22}, unique-id = {32123857}, issn = {1661-6596}, year = {2021}, eissn = {1422-0067}, orcid-numbers = {Lázár, László/0000-0002-2135-8496; Fülöp, Ferenc/0000-0003-1066-5287; Palkó, Márta/0000-0002-8265-7377; Zalán, Zita/0000-0002-7146-3024; Penke, Botond/0000-0003-0938-0567; Fülöp, Lívia/0000-0002-8010-0129; Bogár, Ferenc/0000-0002-0611-1452} } @book{MTMT:3123383, title = {Laboratory investigations in pharmaceutical chemistry}, url = {https://m2.mtmt.hu/api/publication/3123383}, author = {Lázár, László and Miklós, Ferenc and Palkó, Márta and Szakonyi, Zsolt and Zalán, Zita}, editor = {Fülöp, Ferenc and Lázár, László and Szakonyi, Zsolt}, publisher = {SZTE}, unique-id = {3123383}, year = {2015}, orcid-numbers = {Lázár, László/0000-0002-2135-8496; Szakonyi, Zsolt/0000-0003-2432-8409; Zalán, Zita/0000-0002-7146-3024; Fülöp, Ferenc/0000-0003-1066-5287; Lázár, László/0000-0002-2135-8496; Szakonyi, Zsolt/0000-0003-2432-8409} } @book{MTMT:3123382, title = {Gyógyszerészi kémia gyakorlatok}, url = {https://m2.mtmt.hu/api/publication/3123382}, author = {Lázár, László and Miklós, Ferenc and Palkó, Márta and Szakonyi, Zsolt and Zalán, Zita}, editor = {Lázár, László and Fülöp, Ferenc}, publisher = {SZTE}, unique-id = {3123382}, year = {2015}, orcid-numbers = {Lázár, László/0000-0002-2135-8496; Szakonyi, Zsolt/0000-0003-2432-8409; Zalán, Zita/0000-0002-7146-3024; Lázár, László/0000-0002-2135-8496; Fülöp, Ferenc/0000-0003-1066-5287} } @article{MTMT:2275877, title = {Stereoselective synthesis and structural analysis of polycyclic lactams derived from tetrahydroisoquinoline 1,2- and 1,3-diamines}, url = {https://m2.mtmt.hu/api/publication/2275877}, author = {Henri, Kivelä and Olli, Martiskainen and Kalevi, Pihlaja and Zalán, Zita and Lázár, László}, doi = {10.3998/ark.5550190.0013.521}, journal-iso = {ARKIVOC}, journal = {ARKIVOC}, volume = {2012}, unique-id = {2275877}, issn = {1551-7012}, year = {2012}, eissn = {1551-7004}, pages = {244-264}, orcid-numbers = {Zalán, Zita/0000-0002-7146-3024; Lázár, László/0000-0002-2135-8496} } @article{MTMT:1085086, title = {Synthesis And Steric Structure of Pyrrolidine- And Piperidine-fused 1,3,4,2-oxadiazaphosphinanes}, url = {https://m2.mtmt.hu/api/publication/1085086}, author = {Martinek, Tamás and Szolnoki, Éva Tünde and Zalán, Zita and Fülöp, Ferenc}, doi = {10.3998/ark.5550190.0008.516}, journal-iso = {ARKIVOC}, journal = {ARKIVOC}, volume = {2007}, unique-id = {1085086}, issn = {1551-7012}, abstract = {Pyrrolidine- and piperidine-fused 1,3,4,2-oxadiazaphosphinane 2-oxides were prepared by cyclization of the corresponding pyrrolidine-and piperidine-hydrazino alcohols by using phosphorus-containing reagents. Stereochemical and conformational analyses were carried out in order to determine the effect of the ring size on the conformational behavior of the nitrogen-bridged bicyclic system. It was found that the chair conformation in the pyrrolidine-fused 1,3,4,2-oxadiazaphosphinane 2-oxides can be shifted toward twisted or distorted conformations.}, year = {2007}, eissn = {1551-7004}, pages = {202-209}, orcid-numbers = {Martinek, Tamás/0000-0003-3168-8066; Zalán, Zita/0000-0002-7146-3024; Fülöp, Ferenc/0000-0003-1066-5287} } @mastersthesis{MTMT:31156393, title = {Syntheses and ring-closures of difunctional tetrahydroisoquinolines}, url = {https://m2.mtmt.hu/api/publication/31156393}, author = {Zalán, Zita}, publisher = {SZTE}, unique-id = {31156393}, year = {2006}, orcid-numbers = {Zalán, Zita/0000-0002-7146-3024} } @article{MTMT:20316698, title = {Tetrahidroizokinolinvázas difunkciós vegyületek szintézise és gyűrűzárásai [Syntheses and ring-closures of difunctional tetrahydroisoquinolines]}, url = {https://m2.mtmt.hu/api/publication/20316698}, author = {Zalán, Zita}, journal-iso = {ACTA PHARM HUNG}, journal = {ACTA PHARMACEUTICA HUNGARICA}, volume = {76}, unique-id = {20316698}, issn = {0001-6659}, year = {2006}, eissn = {1587-1495}, pages = {155-164}, orcid-numbers = {Zalán, Zita/0000-0002-7146-3024} } @article{MTMT:1078936, title = {Electron ionization mass spectra of phosphorus-containing heterocycles. III. 1,3,4,2-Oxadiazaphosphinane 2-oxides}, url = {https://m2.mtmt.hu/api/publication/1078936}, author = {Juhasz, M and Zalán, Zita and Fülöp, Ferenc and Pihlaja, K}, doi = {10.1002/rcm.2771}, journal-iso = {RAPID COMMUN MASS SPECTR}, journal = {RAPID COMMUNICATIONS IN MASS SPECTROMETRY}, volume = {20}, unique-id = {1078936}, issn = {0951-4198}, abstract = {The 1,3,4,2-oxadiazaphosphinane 2-oxides differ not only in the relative configuration of the P atom (R* or S*) but also in many other ways such as the ring size, ring fusion, P substitution and bridgehead N atom whose effects on their fragmentations have been studied. Some fragmentations resembled those of 3,1,2-oxazaphosphinane 2-oxides and 1,3,2-diazaphosphinane-2-oxides, but new routes were also found, initiated by ionization at the bridgehead N atom. The relative abundances of the molecular ions and some fragment ions allowed the differentiation of cis-trans epimers. Compounds with n = 2 and R=N(CH2CH2Cl)(2), and linearly or angularly isoquinoline-fused isomers in most cases, gave more numerous ions with lower relative abundances than the other compounds in this series. Only the isoquinoline derivatives provided fragments resulting from ionization of the aromatic part of the molecule. Copyright (c) 2006 John Wiley & Sons, Ltd.}, year = {2006}, eissn = {1097-0231}, pages = {3595-3604}, orcid-numbers = {Zalán, Zita/0000-0002-7146-3024; Fülöp, Ferenc/0000-0003-1066-5287} } @article{MTMT:1012941, title = {Electron ionization mass spectra of phosphorus-containing heterocycles. I. 1,4,4a,5,6,7,8,8a-octahydro-2H-3,1,2-benzoxazaphosphinine 2-oxides}, url = {https://m2.mtmt.hu/api/publication/1012941}, author = {Juhasz, M and Martiskainen, O and Zalán, Zita and Fülöp, Ferenc and Pihlaja, K}, doi = {10.1002/rcm.2319}, journal-iso = {RAPID COMMUN MASS SPECTR}, journal = {RAPID COMMUNICATIONS IN MASS SPECTROMETRY}, volume = {20}, unique-id = {1012941}, issn = {0951-4198}, abstract = {The electron ionization mass spectra of 27 cis- and trans-annelated 1,4,4a,5,6,7,8,8a-octahydro-2H-3,1,2-benzoxazaphosphinine 2-oxides were recorded to clarify the effects of the ring heteroatom (O or N), ring annelation, the P configuration and the substituents attached to the ring or to the N and P atoms. For compounds 1-12 different alkyl radical and alkene losses and the cleavage of the P-heteroatom bonds, instead of the P-C bonds, were representative and dependent mainly on the substitution on the N and P atoms. The replacement of Ph and OPh by N(CH2CH2Cl)(2) on the P atom had a dramatic influence on the fragmentation process: new fragment ions were obtained and very little W (1-3%) was formed. Only slight differences were found between some of the corresponding isomers, but interestingly the compounds formed clear groups on the basis of the differences in their fragmentation, depending on the ring-N and ring-P substituents. Copyright (c) 2006 John Wiley & Sons, Ltd.}, year = {2006}, eissn = {1097-0231}, pages = {433-437}, orcid-numbers = {Zalán, Zita/0000-0002-7146-3024; Fülöp, Ferenc/0000-0003-1066-5287} } @article{MTMT:1012939, title = {Synthesis and conformational analysis of tetrahydroisoquinoline and piperidine-fused 1,3,4,2-oxadiazaphosphinanes, new ring systems}, url = {https://m2.mtmt.hu/api/publication/1012939}, author = {Zalán, Zita and Martinek, Tamás and Lázár, László and Sillanpaa, R and Fülöp, Ferenc}, doi = {10.1016/j.tet.2006.01.018}, journal-iso = {TETRAHEDRON}, journal = {TETRAHEDRON}, volume = {62}, unique-id = {1012939}, issn = {0040-4020}, abstract = {Through cyclization of tetrahydroisoquinoline and piperidine 1,2-hydrazino alcohols with phenylphosphonic dichloride and phenyl dichlorophosphate, P-epimeric diastereomers of 1,6,7,11b-tetrahydro-4H-1,3,4,2-oxidiazaphosphino[5,4-a]isoquinoline-3-o xides (13 and 14). 1,6,11,11a-tetrahydro-4H-1,3,4,2-oxadiazaphosphino[4,5-b]isoquinoline-3- oxides (15 and 16) and 1,6,7,8,9,9a-hexahydro-4H-pyrido[1,2-d][1,3,4,2]oxadiazaphosphinane-3-ox ides (17 and 18), the first representatives of these ring systems, were prepared. NMR and X-ray diffraction studies revealed that, independently of the P-substituent and the relative configuration of the phosphorus atom, 13, 14, 17 and 18 could be characterized by trans-connected hetero rings and the chair conformation of the 1,3,4,2-oxadiazaphosphinane moiety, while the stereochemistry of the connection of the hetero rings in the 1,3,4,2-oxidiazaphosphinanes linearly fused to tetrahydroisoquinoline (15 and 16) was found to be dependent on the P-configuration relative to that of the carbon at the annelation. (c) 2006 Elsevier Ltd. All rights reserved.}, year = {2006}, eissn = {1464-5416}, pages = {2883-2891}, orcid-numbers = {Zalán, Zita/0000-0002-7146-3024; Martinek, Tamás/0000-0003-3168-8066; Lázár, László/0000-0002-2135-8496; Fülöp, Ferenc/0000-0003-1066-5287} }