@article{MTMT:34725161, title = {Priméren jelenlévő pszichiátriai zavarok dermatológiai vonatkozásai}, url = {https://m2.mtmt.hu/api/publication/34725161}, author = {HALÁSZ, KATINKA and Remenyik, Éva and Fekete, Zita}, journal-iso = {BVSZ}, journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE}, volume = {100}, unique-id = {34725161}, issn = {0006-7768}, year = {2024}, eissn = {2064-261X}, pages = {43-52} } @article{MTMT:34656442, title = {Fényvédelem a photodermatosisok kezelésében}, url = {https://m2.mtmt.hu/api/publication/34656442}, author = {Csehely, Csilla and Gellén, Emese and Sawhney, Irina and Remenyik, Éva}, doi = {10.7188/bvsz.2023.99.4.4}, journal-iso = {BVSZ}, journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE}, volume = {99}, unique-id = {34656442}, issn = {0006-7768}, abstract = {Light-sensitive skin diseases are known as photodermatoses. Photosensitivity is either an increased and/or unusual reaction to normal light, or an unusual skin reaction –as clinical symptoms-. to lower dose or different composition of light. Genetic and environmental factors have different characteristic roles in their development. Symptoms may develop through metabolic, immunological, or unknown (idiopathic) mechanisms. In many cases, the avoidance of the triggering light and sun protection are of important in the prevention of skin symptoms and in the treatment of photodermatoses. However, the patients' quality of life is negatively affected not only by the symptoms, but also by the daily application of sun protection itself. In this article, the authors highlight that in different photodermatoses, depending on their pathomechanism, different special photoprotection is necessary, and the methods used in the average population are not sufficient. Therefor, the use of disease (action spectrum) – specific, effective, and as simple as possible photoprotection methods is desirable.}, year = {2023}, eissn = {2064-261X}, pages = {263-275} } @article{MTMT:34655720, title = {Az autofágia jelentősége a bőrbetegségek patomechanizmusában}, url = {https://m2.mtmt.hu/api/publication/34655720}, author = {Tósaki, Ágnes and Szabó, Erzsébet Katalin and Szabó, Imre Lőrinc and Remenyik, Éva}, doi = {10.7188/bvsz.2023.99.4.10}, journal-iso = {BVSZ}, journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE}, volume = {99}, unique-id = {34655720}, issn = {0006-7768}, abstract = {Autophagy is a physiological cellular degradation process responsible for the breakdown of damaged, dysfunctional cell organelles and protein aggregates, which is essential for physiological cellular function, growth and development. The aim of this publication is to explain the role of autophagy and its processes in the pathomechanism of certain skin diseases, including psoriasis, atopic dermatitis, vitiligo, hyperpigmentation, systemic lupus erythematosus, skin tumors, melanoma, and infectious skin diseases- and drawing attention to new diagnostic and therapeutic possibilities.}, year = {2023}, eissn = {2064-261X}, pages = {314-321} } @article{MTMT:34517633, title = {Fiatal férfi szisztémás tünetekkel : Behçet szindróma vagy ANCA vasculitis?}, url = {https://m2.mtmt.hu/api/publication/34517633}, author = {Markóth, Csilla and Nagy-Vincze, Melinda and Bidiga, László and Remenyik, Éva and Balla, József and Mátyus, János}, journal-iso = {HYPERTONIA NEPHROLOGIA}, journal = {HYPERTONIA ÉS NEPHROLOGIA}, volume = {27}, unique-id = {34517633}, issn = {1418-477X}, year = {2023}, eissn = {2498-6259}, pages = {35} } @article{MTMT:33122647, title = {KDM1A inhibition increases UVA toxicity and enhances photodynamic therapy efficacy}, url = {https://m2.mtmt.hu/api/publication/33122647}, author = {Mudambi, Shaila and Fitzgerald, Megan and Pera, Paula and Washington, Deschana and Chamberlain, Sarah and Fidrus, Eszter and Hegedűs, Csaba and Remenyik, Éva and Shafirstein, Gal and Bellnier, David and Paragh, Gyorgy}, doi = {10.1111/phpp.12826}, journal-iso = {PHOTODERMATOL PHOTO}, journal = {PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE}, volume = {39}, unique-id = {33122647}, issn = {0905-4383}, year = {2023}, eissn = {1600-0781}, pages = {226-234} } @article{MTMT:34655750, title = {Fényérzékenységgel járó genodermatózisok, porphyriák}, url = {https://m2.mtmt.hu/api/publication/34655750}, author = {Scheili, Andrea and Tósaki, Ágnes and Horkay, Irén and Remenyik, Éva}, doi = {10.7188/bvsz.2022.98.4.1}, journal-iso = {BVSZ}, journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE}, volume = {98}, unique-id = {34655750}, issn = {0006-7768}, abstract = {Sunlight has many biological effects. If the average or low dose of light produces more pronounced, intense, or unusual acute or chronic skin symptoms, it is called photosensitivity. Rarely, photosensitivity is due to a genetic abnormality. Genophotodermatoses result in photosensitivity due to mutations in proteins with a protective function against light, while porphyrias result in the accumulation of phototoxic metabolites. Most of them also have a genetic background. The present report describes these diseases in the light of the latest literature data but does not cover diseases associated with melanin synthesis, which also results in photosensitivity.}, year = {2022}, eissn = {2064-261X}, pages = {198-210} } @article{MTMT:32604600, title = {Treatment of pemphigus vulgaris and foliaceus with efgartigimod, a neonatal Fc receptor inhibitor: a phase II multicentre, open-label feasibility trial}, url = {https://m2.mtmt.hu/api/publication/32604600}, author = {Goebeler, M. and Csörgő Sándorné Bata, Zsuzsanna and De Simone, C. and Didona, B. and Remenyik, Éva and Reznichenko, N. and Stoevesandt, J. and Ward, E. S. and Parys, W. and de Haard, H. and Dupuy, P. and Verheesen, P. and Schmidt, E. and Joly, P.}, doi = {10.1111/bjd.20782}, journal-iso = {BRIT J DERMATOL}, journal = {BRITISH JOURNAL OF DERMATOLOGY}, volume = {186}, unique-id = {32604600}, issn = {0007-0963}, abstract = {Background Pemphigus vulgaris and pemphigus foliaceus are potentially life-threatening autoimmune disorders triggered by IgG autoantibodies against mucosal and epidermal desmogleins. There is an unmet need for fast-acting drugs that enable patients to achieve early sustained remission with reduced corticosteroid reliance. Objectives To investigate efgartigimod, an engineered Fc fragment that inhibits the activity of the neonatal Fc receptor, thereby reducing serum IgG levels, for treating pemphigus. Methods Thirty-four patients with mild-to-moderate pemphigus vulgaris or foliaceus were enrolled in an open-label phase II adaptive trial. In sequential cohorts, efgartigimod was dosed at 10 or 25 mg kg(-1) intravenously with various dosing frequencies, as monotherapy or as add-on therapy to low-dose oral prednisone. Safety endpoints comprised the primary outcome. The study is registered at ClinicalTrials.gov (identifier NCT03334058). Results Adverse events were mostly mild and were reported by 16 of 19 (84%) patients receiving efgartigimod 10 mg kg(-1) and 13 of 15 (87%) patients receiving 25 mg kg(-1), with similar adverse event profiles between dose groups. A major decrease in serum total IgG and anti-desmoglein autoantibodies was observed and correlated with improved Pemphigus Disease Area Index scores. Efgartigimod, as monotherapy or combined with prednisone, demonstrated early disease control in 28 of 31 (90%) patients after a median of 17 days. Optimized, prolonged treatment with efgartigimod in combination with a median dose of prednisone 0 center dot 26 mg kg(-1) per day (range 0 center dot 06-0 center dot 48) led to complete clinical remission in 14 of 22 (64%) patients within 2-41 weeks. Conclusions Efgartigimod was well tolerated and exhibited an early effect on disease activity and outcome parameters, providing support for further evaluation as a therapy for pemphigus.}, keywords = {IGG; rituximab; immunoadsorption}, year = {2022}, eissn = {1365-2133}, pages = {429-439}, orcid-numbers = {Csörgő Sándorné Bata, Zsuzsanna/0000-0002-3732-1743} } @article{MTMT:31891731, title = {Resource utilization, work productivity and costs in patients with hidradenitis suppurativa: a cost-of-illness study}, url = {https://m2.mtmt.hu/api/publication/31891731}, author = {Gáspár, Krisztián and Gergely, László Hunor and Jenei, Balázs and Wikonkál, Norbert and Kinyó, Ágnes and Szegedi, Andrea and Remenyik, Éva and Kiss, Norbert and Jin, Xiang and Sárdy, Miklós and Beretzky, Zsuzsanna and Péntek, Márta and Gulácsi, László and Bánvölgyi, András and Brodszky, Valentin and Rencz, Fanni}, doi = {10.1080/14737167.2021.1895753}, journal-iso = {EXPERT REV PHARMACOECON OUTCOMES RES}, journal = {EXPERT REVIEW OF PHARMACOECONOMICS AND OUTCOMES RESEARCH}, volume = {22}, unique-id = {31891731}, issn = {1473-7167}, year = {2022}, eissn = {1744-8379}, pages = {399-408}, orcid-numbers = {Gergely, László Hunor/0000-0001-5266-4667; Wikonkál, Norbert/0000-0003-4949-8711; Kinyó, Ágnes/0000-0002-9827-2690; Szegedi, Andrea/0000-0003-2109-9014; Kiss, Norbert/0000-0002-9947-1755; Sárdy, Miklós/0000-0003-4306-5093; Péntek, Márta/0000-0001-9636-6012; Gulácsi, László/0000-0002-9285-8746; Bánvölgyi, András/0000-0002-7071-1364; Brodszky, Valentin/0000-0002-6095-2295; Rencz, Fanni/0000-0001-9674-620X} } @article{MTMT:32737060, title = {Bőrgyógyászati tüneteket okozó felnőttkori szisztémás vírusinfekciókszemelvények}, url = {https://m2.mtmt.hu/api/publication/32737060}, author = {Tósaki, Ágnes and Remenyik, Éva}, doi = {10.7188/bvsz.2021.97.2.6}, journal-iso = {BVSZ}, journal = {BŐRGYÓGYÁSZATI ÉS VENEROLÓGIAI SZEMLE}, volume = {97}, unique-id = {32737060}, issn = {0006-7768}, abstract = {A vírusfertőzések egyre inkább globális egészségügyi problémát jelentenek, de nemcsak az aktuális COVID pandémia és akut betegségek, hanem a hosszútávú következmények miatt is. A szerzők röviden ismertetik a hepatitis B és C, valamint trópusi vírusbetegségek (dengue, Zika, chikungunya) tankönyvi jellegzetességeit, a bőrgyógyászati tünetekre koncentrálva és rövid aktuális irodalmi áttekintést is nyújtanak, valamint a hazai vonatkozásokat említik meg az egyes kórokozókkal kapcsolatosan.}, year = {2021}, eissn = {2064-261X}, pages = {108-114} } @article{MTMT:32500479, title = {The time-dependency of the cyclobutane pyrimidine dimer-evoked cellular damages using a CPD-specific photolyase-encoding mRNA-based model system}, url = {https://m2.mtmt.hu/api/publication/32500479}, author = {Hegedűs, Csaba and Fidrus, E. and Boros, Gábor and Janka, Eszter Anna and Emri, Gabriella and Karikó, Katalin and Remenyik, Éva}, doi = {10.1016/j.jid.2021.08.307}, journal-iso = {J INVEST DERMATOL}, journal = {JOURNAL OF INVESTIGATIVE DERMATOLOGY}, volume = {141}, unique-id = {32500479}, issn = {0022-202X}, year = {2021}, eissn = {1523-1747}, pages = {S200-S200}, orcid-numbers = {Janka, Eszter Anna/0000-0003-0724-5281; Karikó, Katalin/0000-0002-1864-3851} }