@article{MTMT:34772955,
	title = {Endometrium development patterns and BMI groups among in vitro fertilization patients; prognostic aspects},
	url = {https://m2.mtmt.hu/api/publication/34772955},
	author = {Vedelek, Viktor and Petra, Bicskei and Mariann, Tábi and Biróné Lajkó, Noémi and Csaba, Ékes and Bereczki, Kristóf and Zsófia, Meixner-Csáti and Sinka, Rita and Vágvölgyi, Anna and Zádori, János},
	doi = {10.3389/fendo.2024.1379109},
	journal-iso = {FRONT ENDOCRINOL},
	journal = {FRONTIERS IN ENDOCRINOLOGY},
	volume = {15},
	unique-id = {34772955},
	issn = {1664-2392},
	year = {2024},
	eissn = {1664-2392},
	orcid-numbers = {Sinka, Rita/0000-0003-4040-4184; Vágvölgyi, Anna/0000-0002-8810-700X}
}

@article{MTMT:34772438,
	title = {Mitochondrial Differentiation during Spermatogenesis: Lessons from Drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/34772438},
	author = {Vedelek, Viktor and Jankovics, Ferenc and Zádori, János and Sinka, Rita},
	doi = {10.3390/ijms25073980},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {25},
	unique-id = {34772438},
	issn = {1661-6596},
	abstract = {Numerous diseases can arise as a consequence of mitochondrial malfunction. Hence, there is a significant focus on studying the role of mitochondria in cancer, ageing, neurodegenerative diseases, and the field of developmental biology. Mitochondria could exist as discrete organelles in the cell; however, they have the ability to fuse, resulting in the formation of interconnected reticular structures. The dynamic changes between these forms correlate with mitochondrial function and mitochondrial health, and consequently, there is a significant scientific interest in uncovering the specific molecular constituents that govern these transitions. Moreover, the specialized mitochondria display a wide array of variable morphologies in their cristae formations. These inner mitochondrial structures are closely associated with the specific functions performed by the mitochondria. In multiple cases, the presence of mitochondrial dysfunction has been linked to male sterility, as it has been observed to cause a range of abnormal spermatogenesis and sperm phenotypes in different species. This review aims to elucidate the dynamic alterations and functions of mitochondria in germ cell development during the spermatogenesis of Drosophila melanogaster.},
	year = {2024},
	eissn = {1422-0067},
	orcid-numbers = {Vedelek, Viktor/0000-0002-0420-8226; Sinka, Rita/0000-0003-4040-4184}
}

@{MTMT:34727182,
	title = {CRISPR-Cas9-based mutant library construction and characterization in Mucor lusitanicus},
	url = {https://m2.mtmt.hu/api/publication/34727182},
	author = {Abu Saleem, Tammam Khaliefeh Siliman and Molnár, Anna and Kovács, Vanda and Kiss, Karina and Rafael, Bence and SZEGEDI, Botond and Sinka, Rita and NÉMETH, Dóra and Homa, Mónika and Vágvölgyi, Csaba and Papp, Tamás and Szebenyi, Csilla and NÉMETH, Dóra},
	booktitle = {Biotechnológiai Szakmai Nap Absztraktfüzet},
	unique-id = {34727182},
	year = {2024},
	pages = {37-39},
	orcid-numbers = {Sinka, Rita/0000-0003-4040-4184; Homa, Mónika/0000-0002-2724-4713; Vágvölgyi, Csaba/0000-0003-0009-7773; Papp, Tamás/0000-0001-8211-5431}
}

@CONFERENCE{MTMT:34684460,
	title = {Convergent evolution in glutamate dehydrogenase activity in Drosophila and human},
	url = {https://m2.mtmt.hu/api/publication/34684460},
	author = {Viktor, Vedelek and Balázs, Vedelek and Gabor, Juhasz and Lőrincz, Péter and Sinka, Rita},
	booktitle = {27th European Drosophila Research Conference},
	unique-id = {34684460},
	year = {2023},
	orcid-numbers = {Lőrincz, Péter/0000-0001-7374-667X; Sinka, Rita/0000-0003-4040-4184}
}

@CONFERENCE{MTMT:34684451,
	title = {Dual role for the orthologue of HECA, Headcase, in blood cell progenitor maintenance in the Drosophila lymph gland},
	url = {https://m2.mtmt.hu/api/publication/34684451},
	author = {Bayan, Kharrat and Nikolett, Virág and Erika, Gábor and Ildikó, Kristó and Aladár, Pettkó-Szandtner and Sinka, Rita and Ferenc, Jankovics and Viktor, Honti},
	booktitle = {27th European Drosophila Research Conference},
	unique-id = {34684451},
	year = {2023},
	orcid-numbers = {Sinka, Rita/0000-0003-4040-4184}
}

@CONFERENCE{MTMT:34684442,
	title = {Versatile ncMTOC organization during spermatogenesis},
	url = {https://m2.mtmt.hu/api/publication/34684442},
	author = {Sinka, Rita and Alzyoud, Elham and Dóra, Németh and Mónika, Krecsmarik and Viktor, Vedelek and Zsuzsánna, Réthi-Nagy and Zoltán, Lipinszki},
	booktitle = {27th European Drosophila Research Conference},
	unique-id = {34684442},
	year = {2023},
	orcid-numbers = {Sinka, Rita/0000-0003-4040-4184}
}

@inbook{MTMT:34680638,
	title = {A Drosophila kutatás története a Szegedi Tudományegyetem Genetika Tanszékén},
	url = {https://m2.mtmt.hu/api/publication/34680638},
	author = {Sinka, Rita},
	booktitle = {Centenáriumi Tanulmánykötet},
	unique-id = {34680638},
	year = {2023},
	pages = {149-163},
	orcid-numbers = {Sinka, Rita/0000-0003-4040-4184}
}

@article{MTMT:34334193,
	title = {Biofilm formation initiating rotifer-specific biopolymer and its predicted components},
	url = {https://m2.mtmt.hu/api/publication/34334193},
	author = {Datki, Zsolt László and Darula, Zsuzsanna and Vedelek, Viktor and Hunyadi-Gulyás Éva, Csilla and Dingmann, Brian J. and Vedelek, Balázs and Kalman, Janos and Urban, Peter and Gyenesei, Attila and Galik-Olah, Zita and Gálik, Bence and Sinka, Rita},
	doi = {10.1016/j.ijbiomac.2023.127157},
	journal-iso = {INT J BIOL MACROMOL},
	journal = {INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES},
	volume = {253},
	unique-id = {34334193},
	issn = {0141-8130},
	abstract = {The rotifer-specific biopolymer, namely Rotimer, is a recently discovered group of the biomolecule family. Rotimer has an active role in the biofilm formation initiated by rotifers (e.g., Euchlanis dilatata or Adineta vaga) or in the female-male sexual interaction of monogononts. To understand the Ca2+- and polarity-dependent formation of this multifunctional viscoelastic material, it is essential to explore its molecular composition. The investigation of the rotifer-enhanced biofilm and Rotimer-inductor conglomerate (RIC) formation yielded several protein candidates to predict the Rotimer-specific main components. The exudate of E. dilatata males was primarily applied from different biopolimer-containing samples (biofilm or RIC). The advantage of males over females lies in their degenerated digestive system and simple anatomy. Thus, their exudate is less contaminated with food and endosymbiont elements. The sequenced and annotated genome and transcriptome of this species opened the way for identifying Rotimer proteins by mass spectrometry. The predicted rotifer-biopolymer forming components are SCO-spondins and 14-3-3 protein. The characteristics of Rotimer are similar to Reissner's fiber, which is found in the central nervous system of vertebrates and is mainly formed from SCO-spondins. This molecular information serves as a starting point for its interdisciplinary investigation and application in biotechnology, biomedicine, or neurodegeneration-related drug development.},
	keywords = {IN-VIVO; PROTEINS; 14-3-3 PROTEIN; ANTIBODY; Biofilm; Ecotoxicology; Clearance; Chemistry, Applied; Biochemistry & Molecular Biology; Rotimer; SCO-spondin},
	year = {2023},
	eissn = {1879-0003},
	orcid-numbers = {Datki, Zsolt László/0000-0002-2537-4741; Vedelek, Balázs/0000-0001-6981-0026; Sinka, Rita/0000-0003-4040-4184}
}

@article{MTMT:34239207,
	title = {A comparative analysis of fruit fly and human glutamate dehydrogenases in Drosophila melanogaster sperm development},
	url = {https://m2.mtmt.hu/api/publication/34239207},
	author = {Vedelek, Viktor and Vedelek, Balázs and Lőrincz, Péter and Juhász, Gábor and Sinka, Rita},
	doi = {10.3389/fcell.2023.1281487},
	journal-iso = {FRONT CELL DEV BIOL},
	journal = {FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY},
	volume = {11},
	unique-id = {34239207},
	issn = {2296-634X},
	abstract = {Glutamate dehydrogenases are enzymes that take part in both amino acid and energy metabolism. Their role is clear in many biological processes, from neuronal function to cancer development. The putative testis-specific Drosophila glutamate dehydrogenase, Bb8, is required for male fertility and the development of mitochondrial derivatives in spermatids. Testis-specific genes are less conserved and could gain new functions, thus raising a question whether Bb8 has retained its original enzymatic activity. We show that while Bb8 displays glutamate dehydrogenase activity, there are significant functional differences between the housekeeping Gdh and the testis-specific Bb8. Both human GLUD1 and GLUD2 can rescue the bb8 ms mutant phenotype, with superior performance by GLUD2. We also tested the role of three conserved amino acids observed in both Bb8 and GLUD2 in Gdh mutants, which showed their importance in the glutamate dehydrogenase function. The findings of our study indicate that Drosophila Bb8 and human GLUD2 could be novel examples of convergent molecular evolution. Furthermore, we investigated the importance of glutamate levels in mitochondrial homeostasis during spermatogenesis by ectopic expression of the mitochondrial glutamate transporter Aralar1, which caused mitochondrial abnormalities in fly spermatids. The data presented in our study offer evidence supporting the significant involvement of glutamate metabolism in sperm development.},
	year = {2023},
	eissn = {2296-634X},
	orcid-numbers = {Vedelek, Balázs/0000-0001-6981-0026; Lőrincz, Péter/0000-0001-7374-667X; Juhász, Gábor/0000-0001-8548-8874; Sinka, Rita/0000-0003-4040-4184}
}

@article{MTMT:34129677,
	title = {Protein Phosphatase 4 Is Required for Centrobin Function in DNA Damage Repair},
	url = {https://m2.mtmt.hu/api/publication/34129677},
	author = {Réthi-Nagy, Zsuzsánna and Ábrahám, Edit and Sinka, Rita and Juhász, Szilvia and Lipinszki, Zoltán},
	doi = {10.3390/cells12182219},
	journal-iso = {CELLS-BASEL},
	journal = {CELLS},
	volume = {12},
	unique-id = {34129677},
	abstract = {Genome stability in human cells relies on the efficient repair of double-stranded DNA breaks, which is mainly achieved by homologous recombination (HR). Among the regulators of various cellular functions, Protein phosphatase 4 (PP4) plays a pivotal role in coordinating cellular response to DNA damage. Meanwhile, Centrobin (CNTRB), initially recognized for its association with centrosomal function and microtubule dynamics, has sparked interest due to its potential contribution to DNA repair processes. In this study, we investigate the involvement of PP4 and its interaction with CNTRB in HR-mediated DNA repair in human cells. Employing a range of experimental strategies, we investigate the physical interaction between PP4 and CNTRB and shed light on the importance of two specific motifs in CNTRB, the PP4-binding FRVP and the ATR kinase recognition SQ sequences, in the DNA repair process. Moreover, we examine cells depleted of PP4 or CNTRB and cells harboring FRVP and SQ mutations in CNTRB, which result in similar abnormal chromosome morphologies. This phenomenon likely results from the impaired resolution of Holliday junctions, which serve as crucial intermediates in HR. Taken together, our results provide new insights into the intricate mechanisms of PP4 and CNTRB-regulated HR repair and their interrelation.},
	year = {2023},
	eissn = {2073-4409},
	orcid-numbers = {Sinka, Rita/0000-0003-4040-4184; Lipinszki, Zoltán/0000-0002-2067-0832}
}