@article{MTMT:34124226, title = {Novel Noninvasive Paraclinical Study Method for Investigation of Liver Diseases}, url = {https://m2.mtmt.hu/api/publication/34124226}, author = {Győrfi, Nina Rubina and Gál, Adrián Róbert and Fincsur, András and Kalmar-Nagy, Karoly and Mintál, Kitti and Hormay, Edina and Miseta, Attila János and Tornóczky, Tamás and Nemeth, Anita K. and Bogner, Péter and Kiss, Tamas and Helyes, Zsuzsanna and Sári, Zoltán and Klincsik, Mihály and Tadity, Vladimir and Lénárd, László and Vereczkei, András and Karádi, Zoltán György and Vizvári, Zoltán Ákos and Tóth, Attila}, doi = {10.3390/biomedicines11092449}, journal-iso = {BIOMEDICINES}, journal = {BIOMEDICINES}, volume = {11}, unique-id = {34124226}, abstract = {Based on a prior university patent, the authors developed a novel type of bioimpedance-based test method to noninvasively detect nonalcoholic fatty liver disease (NAFLD). The development of a new potential NAFLD diagnostic procedure may help to understand the underlying mechanisms between NAFLD and severe liver diseases with a painless and easy-to-use paraclinical examination method, including the additional function to detect even the earlier stages of liver disease. The aim of this study is to present new results and the experiences gathered in relation to NAFLD progress during animal model and human clinical trials.}, keywords = {VALIDATION; clinical study; hepatic steatosis; Wistar; Bioelectrical impedance spectroscopy; NAFLD; noninvasive measurement; low-frequency measurement}, year = {2023}, eissn = {2227-9059}, orcid-numbers = {Mintál, Kitti/0009-0003-4739-2902; Hormay, Edina/0009-0004-0598-5061; Miseta, Attila János/0000-0002-7984-3347} } @article{MTMT:34095179, title = {Deconvolution Analysis of the Non-Ionic Iomeprol, Iobitridol and Iodixanol Contrast Media-Treated Human Whole Blood Thermograms: A Comparative Study}, url = {https://m2.mtmt.hu/api/publication/34095179}, author = {Telek, Elek and Ujfalusi, Zoltán and Nyitrai, Miklós and Bogner, Péter and Lukács, András Szilárd and Németh, Timea and Hild, Gabriella and Hild, Gábor}, doi = {10.3390/diagnostics13152523}, journal-iso = {DIAGNOSTICS}, journal = {DIAGNOSTICS}, volume = {13}, unique-id = {34095179}, issn = {2075-4418}, abstract = {To study the effect of non-ionic contrast media on anticoagulated and non-anticoagulated human whole blood samples, calorimetric measurements were performed. The anticoagulated plasma showed the greatest fall in the total ΔH after Iodixanol treatment. The plasma-free erythrocytes revealed a pronounced shift in the Tmax and a decrease in the ΔH of hemoglobin and transferrin. The total ΔH of Iodixanol treatment showed the highest decline, while Iomeprol and Iobitridol had fewer adverse effects. Similarly, the non-anticoagulated samples revealed a decrease both in the Tmax and the ΔH of albumin and immunoglobulin-specific transitions. The total ΔH showed that Iodixanol had more influence on the serum. The serum-free erythrocyte samples resulted in a significant drop in the Tmax of erythrocyte and transferrin (~5–6 °C). The ΔH of deconvolved hemoglobin and transferrin decreased considerably; however, the ΔH of albumin increased. Surprisingly, compared to Iomeprol and Iobitridol treatments, the total ΔH of Iodixanol was less pronounced in the non-anticoagulated erythrocyte samples. In sum, each non-ionic contrast medium affected the thermal stability of anticoagulated and non-anticoagulated erythrocyte proteins. Interestingly, Iodixanol treatment caused more significant effects. These findings suggest that conformational changes in blood components can occur, which can potentially lead to the increased prevalence of cardiovascular dysfunctions and blood clotting.}, year = {2023}, eissn = {2075-4418}, orcid-numbers = {Telek, Elek/0000-0003-0396-4799; Ujfalusi, Zoltán/0000-0001-5936-7286; Nyitrai, Miklós/0000-0002-6229-4337} } @article{MTMT:34067799, title = {WebMRI: Brain extraction and linear registration in the web browser Brain extraction and linear registration}, url = {https://m2.mtmt.hu/api/publication/34067799}, author = {Harmouche, Ahmed Mouhamad and Kövér, Ferenc and Szukits, Sándor and Dóczi, Tamás Péter and Bogner, Péter and Tóth, Arnold}, doi = {10.1556/1647.2023.00111}, journal-iso = {IMAGING}, journal = {IMAGING}, volume = {15}, unique-id = {34067799}, year = {2023}, eissn = {2732-0960}, pages = {31-36} } @article{MTMT:33708872, title = {Optimal renal artery-aorta angulation revealed by flow simulation}, url = {https://m2.mtmt.hu/api/publication/33708872}, author = {Csonka, Dávid Ciprián and Kalmár Nagy, Károly and Szakály, Péter and Szukits, Sándor and Bogner, Péter and Koller, Ákos and Kun, Szilárd and Wittmann, István and Háber, István Ervin and Horváth, Iván}, doi = {10.1159/000530169}, journal-iso = {KIDNEY BLOOD PRESS R}, journal = {KIDNEY AND BLOOD PRESSURE RESEARCH}, volume = {48}, unique-id = {33708872}, issn = {1420-4096}, abstract = {IntroductionIn blood circulation, the vessel branching angle may have hemodynamic consequences. We hypothesized that there is a hemodynamically optimal range for the renal artery branching angle.MethodsPosttransplant kinetics of eGFR (estimated glomerular filtration rate) data were analyzed regarding the donor and implant sides (right-to-right, left-to-right position) (n=46). The renal artery branching angle from the aorta of a randomly selected population was measured using an X-ray angiogram (n=44). Computational fluid dynamics simulation was used to elucidate the hemodynamic effects of angulation.Results, and DiscussionRenal transplant patients receiving a right donor kidney to the right side showed faster adaptation and higher eGFR values than those receiving a left donor kidney to the right side (eGFR: 65±7 vs 56±6 ml/min/1.73 m2; P <0.01). The average left side branching angle was 78°, and the right side was 66°. Simulation results showed that pressure, volume flow and velocity were relatively constant between 58° and 88°, indicating that this range is optimal for the kidneys. The turbulent kinetic energy shows no significant change between 58° and 78°.ConclusionThe results suggest that there is an optimal range for renal artery branching angle from the aorta where hemodynamic vulnerability caused by the degree of angulation is the lowest, which should be considered during kidney transplantations.}, year = {2023}, eissn = {1423-0143}, pages = {249-259}, orcid-numbers = {Csonka, Dávid Ciprián/0000-0002-6140-6878; Kalmár Nagy, Károly/0000-0003-1044-5540; Koller, Ákos/0000-0003-3256-8701} } @article{MTMT:33687471, title = {A vérnyomás hatása a veseartéria áramlástani jellemzőire egészséges és fél vese esetén}, url = {https://m2.mtmt.hu/api/publication/33687471}, author = {Csonka, Dávid Ciprián and Szukits, Sándor and Bogner, Péter and Koller, Ákos and Wittmann, István and Háber, István Ervin and Horváth, Iván}, doi = {10.33668/hn.27.007}, journal-iso = {HYPERTONIA NEPHROLOGIA}, journal = {HYPERTONIA ÉS NEPHROLOGIA}, volume = {27}, unique-id = {33687471}, issn = {1418-477X}, abstract = {A vérnyomás változása befolyásolhatja az áramlástani jellemzőket, és ezáltal a vesék hemodinamikáját is. Fél vesés állapotban ez a hatás még jelentősebb lehet. A veseartéria környezetének in vivo mérhetetlen áramlástani jellemzőit numerikus áramlástani szimulációval hatékonyan lehet vizsgálni. A kutatás elsődleges célja annak bizonyítása volt, hogy a magas vérnyomás és az izolált szisztolés hypertonia változásokat eredményez a veseartéria áramlástani jellemzőiben, amelyek fél vesés esetben jelentősebbek. Módszer: Egy véletlenszerűen kiválasztott betegcsoport aorta-veseartéria jobb és bal oldali elágazási szögeit mértük retrospektív módon, in vivo. A veseartéria áramlástani jellemzőinek mérésére egy numerikus áramlástani szimulációsorozatot végeztünk egészséges és fél vesés modelleken. A vérnyomást először fokozatosan növeltük 120/80 Hgmm értékről 200/90 Hgmm értékig. Ezt követően az izolált szisztolés hypertonia esetét szimuláltuk a diasztolés vérnyomást fokozatosan csökkentve 200/50 Hgmm értékig. A szimuláció kimenő paraméterei a nyomás, turbulens kinetikus energia, sebesség és térfogatáram értékei voltak a veseartériák kilépő keresztmetszetén. Eredmény: A veseartéria-elágazási szögek átlaga a bal oldalon 78°, a jobb oldalon 66° volt. A szimuláció eredményei azt mutatták, hogy a magas vérnyomás és az izolált szisztolés hypertonia következetesen változtatják a veseartéria áramlástani jellemzőit, fél vesés esetben nagyobb mértékben. Konklúziók: A vesét károsíthatja a nagyobb nyomás, a turbulencianövekedés atherosclerosishoz vezethet a veseartéria elágazásánál. Ezek a jellemzők nagyobb mértékben változnak fél vesés állapotban, így ez veszélyesebb a vesére nézve. Az áramlási sebesség és térfogatáram értékei azonban nem függenek szignifikánsan a fél vesés állapottól.}, year = {2023}, eissn = {2498-6259}, pages = {7-12}, orcid-numbers = {Csonka, Dávid Ciprián/0000-0002-6140-6878; Koller, Ákos/0000-0003-3256-8701} } @article{MTMT:33130331, title = {A szervezett lakossági mammográfiás emlőszűrés részvételi mutatói 2012–2021 között Magyarországon}, url = {https://m2.mtmt.hu/api/publication/33130331}, author = {Laczó, Andrea and Bódis, József and Bogner, Péter and Molnár, Krisztián and Vajda, Réka and Pónusz-Kovács, Dalma and Elmer, Diána and Kajos, Luca Fanni and Csákvári, Tímea and Kívés, Zsuzsanna and Boncz, Imre}, journal-iso = {MAGYAR ONKOLÓGIA}, journal = {MAGYAR ONKOLÓGIA}, volume = {66}, unique-id = {33130331}, issn = {0025-0244}, abstract = {The aim of our study is to analyze the participation indicators of screening rounds Nr. 6-10 (2012-2021) of the organized nationwide mammography screening program. Data derived from the nationwide financing database of the Hungarian National Health Insurance Fund Management and covered the period 2012-2021. We analyzed both diagnostic and screening mammography examinations. Between 2012 and 2019 the coverage (screening and diagnostic mammography) varied between 48.1-51.5, which decreased to 31.8% in 2020-2021. Within total coverage, the organized screening rate declined from 30.3-31.2 to 20.0, while the diagnostic mammography rate decreased from 17.7-20.7% to 11.8%. We can conclude that the number of both the diagnostic and screening mammography declined. In order to reduce the mortality of breast cancer, participation rate of mammography screening program should be increased.}, year = {2022}, eissn = {2060-0399}, pages = {195-200}, orcid-numbers = {Kajos, Luca Fanni/0000-0002-0574-5787; Csákvári, Tímea/0000-0002-3339-4953; Boncz, Imre/0000-0003-3699-6236} } @article{MTMT:33123902, title = {New CFD-based method for morphological and functional assessment in cardiovascular skill training}, url = {https://m2.mtmt.hu/api/publication/33123902}, author = {Wlasitsch-Nagy, Zsófia and Bálint, Alexandra and Kőnigné Péter, Anikó and Varga, Péter and Várady, Edit and Bogner, Péter and Gasz, Balázs}, doi = {10.1016/j.jvscit.2022.09.012}, journal-iso = {J VASC SURG CASES IN TECH}, journal = {JOURNAL OF VASCULAR SURGERY CASES AND INNOVATIVE TECHNIQUES}, volume = {8}, unique-id = {33123902}, issn = {2468-4287}, year = {2022}, pages = {770-778}, orcid-numbers = {Bálint, Alexandra/0000-0002-7267-8633} } @misc{MTMT:33049904, title = {Computational fluid dynamics model reveals an optimal range for renal artery-aorta branching angle}, url = {https://m2.mtmt.hu/api/publication/33049904}, author = {Csonka, Dávid Ciprián and Károly, Kalmár Nagy and Péter, Szakály and Szukits, Sándor and Bogner, Péter and Koller, Ákos and Wittmann, István and Háber, István Ervin and Horváth, Iván}, unique-id = {33049904}, year = {2022}, orcid-numbers = {Csonka, Dávid Ciprián/0000-0002-6140-6878; Koller, Ákos/0000-0003-3256-8701} } @article{MTMT:32847474, title = {Plasma Levels and Renal Handling of Amino Acids Contribute to Determination of Risk of Mortality or Feed of Ventilation in Patients with COVID-19.}, url = {https://m2.mtmt.hu/api/publication/32847474}, author = {Bánfai, Gábor László and Kanizsai, Péter László and Csontos, Csaba and Kun, Szilárd and Lakatos, Ágnes and Lajtai, Anikó and Lelovics, V. and Szukits, Sándor and Bogner, Péter and Miseta, Attila János and Wittmann, István and Molnár, Gergő Attila}, doi = {10.3390/metabo12060486}, journal-iso = {METABOLITES}, journal = {METABOLITES}, volume = {12}, unique-id = {32847474}, issn = {2218-1989}, year = {2022}, eissn = {2218-1989}, orcid-numbers = {Kanizsai, Péter László/0000-0001-7896-2857; Miseta, Attila János/0000-0002-7984-3347; Molnár, Gergő Attila/0000-0001-6052-5907} } @article{MTMT:32653646, title = {The effect of Iodixanol on the thermodynamic properties of blood components}, url = {https://m2.mtmt.hu/api/publication/32653646}, author = {Ujfalusi, Zoltán and Telek, Elek and Nyitrai, Miklós and Bogner, Péter and Rostás, Tamás and Hild, Gabriella and Trif, László and Hild, Gábor}, doi = {10.1016/j.tca.2022.179165}, journal-iso = {THERMOCHIM ACTA}, journal = {THERMOCHIMICA ACTA}, volume = {710}, unique-id = {32653646}, issn = {0040-6031}, year = {2022}, eissn = {1872-762X}, orcid-numbers = {Ujfalusi, Zoltán/0000-0001-5936-7286; Telek, Elek/0000-0003-0396-4799; Nyitrai, Miklós/0000-0002-6229-4337; Trif, László/0000-0002-3960-1829} }