TY - JOUR AU - Steigmann, Larissa AU - Kačarević, Željka Perić AU - Khoury, Jessica AU - Nagy, Katalin AU - Feres, Magda TI - Integration of precision medicine into the dental care setting JF - FRONTIERS IN DENTAL MEDICINE J2 - FRONT. DENT. MED. VL - 5 PY - 2024 PG - 9 SN - 2673-4915 DO - 10.3389/fdmed.2024.1398897 UR - https://m2.mtmt.hu/api/publication/35383453 ID - 35383453 N1 - Department of Oral Medicine, Infection, and Immunity, Division of Periodontology, Harvard School of Dental Medicine, Boston, MA, United States Department of Anatomy, Histology, Embryology, Pathology Anatomy and Pathology Histology, Faculty of Dental Medicine and Health Osijek, J.J. Strossmayer University of Osijek, Osijek, Croatia Department of Oral Biology, The Goldschleger School of Dental Medicine, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Department of Oral Surgery, Faculty of Dentistry, University of Szeged, Szeged, Hungary Export Date: 14 November 2024 Correspondence Address: Steigmann, L.; Department of Oral Medicine, United States; email: larissa_steigmann@hsdm.harvard.edu LA - English DB - MTMT ER - TY - JOUR AU - Riba, Magdolna ED - Nagy, Katalin / Interviewed person TI - Jó hírünk a "Nagyvilágban"... Prof. Dr. Nagy Katalinnal beszélgettünk ugandai útjának tapasztalatairól és élményeiről JF - DENTAL HÍREK: A FOGÁSZATI SZAKMA INFORMÁCIÓS MAGAZINJA J2 - DENTAL HÍREK VL - 28 PY - 2024 IS - 1 SP - 30 EP - 33 PG - 4 SN - 1419-2918 UR - https://m2.mtmt.hu/api/publication/34856544 ID - 34856544 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Urbán, István András AU - Mirsky, Nicholas AU - Serroni, Matteo AU - Tovar, Nick AU - Nayak, Vasudev Vivekanand AU - Witek, Lukasz AU - Marin, Charles AU - Saleh, Muhammed AU - Ravidà, Andrea AU - Baczkó, István AU - Párkányi, László AU - Nagy, Katalin AU - Coelho, Paulo G TI - Elucidating the Benefit of Perforated vs Non-Perforated Membranes in Guided Bone Regeneration: An in Vivo Histologic Evaluation and Histomorphometric Analysis JF - INTERNATIONAL JOURNAL OF PERIODONTICS & RESTORATIVE DENTISTRY J2 - INT J PERIODONT REST PY - 2024 SN - 0198-7569 DO - 10.11607/prd.7110 UR - https://m2.mtmt.hu/api/publication/34850170 ID - 34850170 AB - Background: Non-perforated Polytetrafluoroethylene (PTFE) membranes are effectively utilized in guided bone regeneration (GBR) but may hinder cell migration due to limited interaction with the periosteum. This study compared bone regeneration using occlusive or perforated membranes combined with acellular collagen sponge (ACS) and recombinant human bone morphogenic protein-2 (rhBMP-2) in a canine mandibular model. Material and Methods: Male beagle dogs (n=3) received two mandibular defects each to compare ACS/rhBMP-2 with experimental (perforated group) and control (non-perforated group) membranes (n=3 defects/group). Tissue healing was assessed histomorphologically, histomorphometrically and through volumetric reconstruction using microcomputed tomography. Results: The perforated group showed increased bone formation and reduced soft tissue formation compared to the non-perforated group. For the primary outcome, histomorphometric analysis revealed significantly greater total regenerated bone in the perforated group (67.08 ± 6.86%) relative to the nonperforated group (25.18 ± 22.44%) (p = 0.036). Perforated membranes had less soft tissue infiltration (32.91 ± 6.86%) compared to non-perforated membranes (74.82 ± 22.44%) (p = 0.036). Conclusion: The increased permeability of membranes in the perforated group potentially enabled periosteal precursor cells greater accessibility to rhBMP-2. The availability may have accelerated their differentiation into mature bone-forming cells, contributing to the stimulation of new bone production, relative to the non-perforated group. LA - English DB - MTMT ER - TY - JOUR AU - Sadid‐Zadeh, Ramtin AU - Lin, Kevin AU - Li, Rui AU - Nagy, Katalin TI - Fracture strength of screw‐retained zirconia crowns assembled on zirconia and titanium implants JF - JOURNAL OF PROSTHODONTICS-IMPLANT ESTHETIC AND RECONSTRUCTIVE DENTISTRY J2 - J PROSTHODONT VL - 33 PY - 2024 IS - 3 SP - 273 EP - 280 PG - 8 SN - 1059-941X DO - 10.1111/jopr.13683 UR - https://m2.mtmt.hu/api/publication/34752686 ID - 34752686 LA - English DB - MTMT ER - TY - JOUR AU - Aghasizadeh Sherbaf, Reza AU - Kaposvári, George Michel AU - Nagy, Katalin AU - Álmos, Péter Zoltán AU - Baráth, Zoltán Lajos AU - Varga-Matusovits, Danica TI - Oral Health Status and Factors Related to Oral Health in Patients with Schizophrenia: A Matched Case-Control Observational Study JF - JOURNAL OF CLINICAL MEDICINE J2 - J CLIN MED VL - 13 PY - 2024 IS - 6 PG - 13 SN - 2077-0383 DO - 10.3390/jcm13061584 UR - https://m2.mtmt.hu/api/publication/34728780 ID - 34728780 LA - English DB - MTMT ER - TY - JOUR AU - Pozzi, Alessandro AU - Agliardi, Enrico AU - Lio, Fabrizio AU - Nagy, Katalin AU - Nardi, Alessandra AU - Arcuri, Lorenzo TI - Accuracy of intraoral optical scan versus stereophotogrammetry for complete-arch digital implant impression: An in vitro study JF - JOURNAL OF PROSTHODONTIC RESEARCH J2 - J PROSTHODONT RES VL - 68 PY - 2024 IS - 1 SP - 172 EP - 180 PG - 9 SN - 1883-1958 DO - 10.2186/jpr.JPR_D_22_00251 UR - https://m2.mtmt.hu/api/publication/34118614 ID - 34118614 AB - To assess and compare the accuracies of intraoral scanners (IOS) and stereophotogrammetry (SPG) devices for complete-arch digital implant impressions.A 4-analog model was digitized using a desk scanner to obtain a reference file. Thirty test scans were conducted using the investigated IOS device, while an additional 30 scans were performed using the SPG device. Using the best-fit algorithm, the resulting 60 test files were aligned with the reference file. Linear (ΔX, ΔY, and ΔZ-axis) and angular deviations (ΔANGLE) were evaluated. Three-dimensional (3D) deviation was calculated based on the Euclidean distance (ΔEUC). The analysis was stratified according to the scanning device and implant position. Fisher's F and t-tests were used to compare the variances and expected values of the two scanning systems.IOS expressed a higher 3D (ΔEUC) mean deviation than SPG (52.8 µm vs. 33.4 µm, P < 0.0001), with extreme measurements up to 181.9 µm. A significantly higher standard deviation (SD) was associated with IOS (37.1 µm vs. 17.7 µm, P < 0.0001). Considering angular deviations, the IOS showed slightly higher angular mean deviations (ΔANGLE) than the SPG (0.28° vs. 0.24°, P = 0.0022), with extreme measurements of up to 0.73°. The SPG SD values were significantly lower than the IOS SD values (0.14° vs. 0.04°, P < 0.0001).The SPG showed significantly higher 3D and angular accuracies for complete arch implant impressions, with consistent repeatability. IOS scanning revealed significantly higher extreme deviations exceeding the acceptable threshold value. Despite study limitations, SPG appears more feasible than IOS for complete-arch digital implant impressions. LA - English DB - MTMT ER - TY - JOUR AU - Riba, Magdolna ED - Nagy, Katalin / Interviewed person TI - Jó hírünk a "Nagyvilágban"... Prof. Dr. Nagy Katalinnal beszélgettünk kolumbiai útjának tapasztalatairól és élményeiről JF - DENTAL HÍREK: A FOGÁSZATI SZAKMA INFORMÁCIÓS MAGAZINJA J2 - DENTAL HÍREK VL - 27 PY - 2023 IS - 1 SP - 24 EP - 28 PG - 5 SN - 1419-2918 UR - https://m2.mtmt.hu/api/publication/34856419 ID - 34856419 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Du, Toit Jonathan AU - Salama, Maurice AU - Gluckman, Howard AU - Nagy, Katalin TI - The root submergence technique at single tooth sites to short-span edentulous sites: A step-by-step partial extraction therapy protocol JF - JOURNAL OF PROSTHETIC DENTISTRY J2 - J PROSTHET DENT VL - 130 PY - 2023 IS - 2 SP - 146 EP - 154 PG - 9 SN - 0022-3913 DO - 10.1016/j.prosdent.2021.10.004 UR - https://m2.mtmt.hu/api/publication/34830213 ID - 34830213 AB - Submerging roots for ridge preservation was the earliest partial extraction therapy and has been described since the 1970s. Despite the approximately 47 animal and human studies published since, an updated and contemporary step-by-step protocol has not yet been provided. This technique report describes in detail how to manage submerged roots at single tooth sites and at short-span edentulous areas. (J Prosthet Dent 2023;130:146-54) LA - English DB - MTMT ER - TY - JOUR AU - Chackartchi, Tali AU - Imber, Jean-Claude AU - Stähli, Alexandra AU - Bosshardt, Dieter AU - Sacks, Hagit AU - Nagy, Katalin AU - Sculean, Anton TI - Healing of intrabony defects using a novel human recombinant amelogenin: a preclinical study JF - QUINTESSENCE INTERNATIONAL J2 - QUINTESSENCE INT VL - 54 PY - 2023 IS - 8 SP - 622 EP - 628 PG - 7 SN - 0033-6572 DO - 10.3290/j.qi.b4007601 UR - https://m2.mtmt.hu/api/publication/34196844 ID - 34196844 N1 - Department of Periodontology, Hadassah Medical Center, Faculty of Dental Medicine, Hebrew University, Jerusalem, Israel Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland VP R&D Prudentix, Israel Department of Oral Surgery, Faculty of Dentistry, University of Szeged, Szeged, Hungary Export Date: 04 January 2024; Cited By: 1; Correspondence Address: A. Sculean; Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Freiburgstrasse 7, 3010, Switzerland; email: anton.sculean@unibe.ch AB - OBJECTIVE: To histologically evaluate the effects of a novel human recombinant amelogenin (rAmelX) on periodontal wound healing/regeneration in intrabony defects. METHOD AND MATERIALS: Intrabony defects were surgically created in the mandible of three minipigs. Twelve defects were randomly treated with either rAmelX and carrier (test group) or with the carrier only (control group). At 3 months following reconstructive surgery, the animals were euthanized, and the tissues histologically processed. Thereafter, descriptive histology, histometry, and statistical analyses were performed. RESULTS: Postoperative clinical healing was uneventful. At the defect level, no adverse reactions (eg, suppuration, abscess formation, unusual inflammatory reaction) were observed with a good biocompatibility of the tested products. The test group yielded higher values for new cementum formation (4.81 ± 1.17 mm) compared to the control group (4.39 ± 1.71 mm) without reaching statistical significance (P = .937). Moreover, regrowth of new bone was greater in the test compared to the control group (3.51 mm and 2.97 mm, respectively, P = .309). CONCLUSIONS: The present results provided for the first-time histologic evidence for periodontal regeneration following the use of rAmelX in intrabony defects, thus pointing to the potential of this novel recombinant amelogenin as a possible alternative to regenerative materials from animal origins. LA - English DB - MTMT ER - TY - JOUR AU - Chackartchi, Tali AU - Bosshardt, Dieter D. AU - Imber, Jean-Claude AU - Staehli, Alexandra AU - Sacks, Hagit AU - Nagy, Katalin AU - Sculean, Anton TI - Histological evaluation following treatment of recession-type defects with coronally advanced flap and a novel human recombinant amelogenin JF - CLINICAL ORAL INVESTIGATIONS J2 - CLIN ORAL INVEST VL - 27 PY - 2023 IS - 9 SP - 5041 EP - 5048 PG - 8 SN - 1432-6981 DO - 10.1007/s00784-023-05123-x UR - https://m2.mtmt.hu/api/publication/34196835 ID - 34196835 N1 - Department of Periodontology, Hadassah Medical Center, Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, Israel Robert K. Schenk Laboratory of Oral Histology, Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland Department of Periodontology, School of Dental Medicine, University of Bern, Freiburgstrasse 7, Bern, 3010, Switzerland VP R&D Prudentix. Ltd., Lod, Israel Department of Oral Surgery, Faculty of Dentistry, University of Szeged, Szeged, Hungary Export Date: 04 January 2024; Cited By: 0; Correspondence Address: A. Sculean; Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Freiburgstrasse 7, 3010, Switzerland; email: anton.sculean@unibe.ch AB - ObjectivesTo histologically evaluate the effects of a novel human recombinant amelogenin (rAmelX) on periodontal wound healing / regeneration in recession-type defects.Materials and methodsA total of 17 gingival recession-type defects were surgically created in the maxilla of three minipigs. The defects were randomly treated with a coronally advanced flap (CAF) and either rAmelX (test), or a CAF and placebo (control). At three months following reconstructive surgery, the animals were euthanized, and the healing outcomes histologically evaluated.ResultsThe test group yielded statistically significantly (p = 0.047) greater formation of cementum with inserting collagen fibers compared with the control group (i.e., 4.38 mm & PLUSMN; 0.36 mm vs. 3.48 mm & PLUSMN; 1.13 mm). Bone formation measured 2.15 mm & PLUSMN; 0.8 mm in the test group and 2.24 mm & PLUSMN; 1.23 mm in the control group, respectively, without a statistically significant difference (p = 0.94).ConclusionsThe present data have provided for the first-time evidence for the potential of rAmelX to promote regeneration of periodontal ligament and root cementum in recession-type defects, thus warranting further preclinical and clinical testing. LA - English DB - MTMT ER -