@article{MTMT:35613051, title = {Correlation Between the Pitch and Loudness of Tinnitus, Hearing Levels, and Tinnitus Handicap Inventory Scores in Patients with Chronic Subjective Tinnitus}, url = {https://m2.mtmt.hu/api/publication/35613051}, author = {Mavrogeni, Panayiota and Molnár, András and Molnár, Viktória and Tamás, László and Maihoub, Stefani}, doi = {10.3390/jcm13237261}, journal-iso = {J CLIN MED}, journal = {JOURNAL OF CLINICAL MEDICINE}, volume = {13}, unique-id = {35613051}, abstract = {Objectives: The aim of this study was to investigate the relationships between tinnitus pitch and loudness, the frequency of hearing loss, hearing level, and the Tinnitus Handicap Inventory (THI) scores reported by patients. Methods: In total, 139 patients (50 men and 89 women; mean age ± SD, 60.19 ± 11.47 years) who suffered from chronic primary tinnitus associated with sensorineural hearing loss were included in the study. Participants underwent pure-tone audiometry and tinnitus pitch matching assessments. Additionally, all participants completed the Hungarian version of the THI questionnaire. Correlations were assessed using simple linear, Spearman’s, and Pearson’s correlation tests, and a linear regression model was applied. The Mann–Whitney U test was also used. Results: This study identified a significant correlation between the pitch of tinnitus and the frequency of hearing loss (p = 0.000 *; rho = 0.549). There was also a significant correlation between tinnitus noise and hearing levels (p = 0.000 *; rho = 0.375). Age was shown to significantly affect tinnitus loudness (p = 0.016 *) and hearing levels (p = 0.000 *) as determined by a linear regression model. Tinnitus duration only significantly influenced tinnitus loudness (p = 0.022). There was no significant effect of sex on tinnitus or audiometry parameters. Total THI scores were influenced solely by tinnitus loudness (p = 0.021 *). Furthermore, sex did have an effect on total THI scores, with women reporting higher scores (p = 0.000 *). Conclusions: This study concluded that there is a significant correlation between the pitch and loudness of tinnitus and hearing levels, suggesting a connection in their underlying mechanisms. The intensity of tinnitus and hearing level are primarily affected by ageing processes. Furthermore, the severity of self-perceived tinnitus is mainly related to the loudness of tinnitus.}, keywords = {Hearing loss; Tinnitus Handicap Inventory; Hearing level; tinnitus pitch; tinnitus loudness; hearing loss frequency}, year = {2024}, eissn = {2077-0383}, orcid-numbers = {Molnár, András/0000-0002-4417-5166; Molnár, Viktória/0000-0002-2508-4429; Tamás, László/0000-0003-3723-9149} } @article{MTMT:35477568, title = {A PNI (Prognostic Nutritional Index) a többi tápláltsági státusz markernél jobban korrelál a túléléssel fej-nyaki daganatok esetén}, url = {https://m2.mtmt.hu/api/publication/35477568}, author = {Uri, Imre and Horváth, Angéla and Tamás, László and Polony, Gábor and Dános, Kornél}, journal-iso = {FÜL-ORR-GÉGEGYÓGYÁSZAT}, journal = {FÜL-ORR-GÉGEGYÓGYÁSZAT}, volume = {70}, unique-id = {35477568}, issn = {0016-237X}, year = {2024}, pages = {151}, orcid-numbers = {Tamás, László/0000-0003-3723-9149} } @article{MTMT:35417664, title = {Potential Prognostic Role of Protein Kinase D Isoforms in Head and Neck Cancers}, url = {https://m2.mtmt.hu/api/publication/35417664}, author = {Gurbi, Bianka and Dános, Kornél and Birtalan, Ede and Krenács, Tibor and Kovács, Borbála and Tamás, László and Csala, Miklós and Varga, Attila}, doi = {10.3390/ijms251910274}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {25}, unique-id = {35417664}, issn = {1661-6596}, abstract = {Head and neck squamous cell carcinomas (HNSCC) are among the most common malignancies in men worldwide. Nevertheless, their clinical management is hampered by the limited availability of reliable predictive and prognostic biomarkers. Protein kinase D (PKD) isoforms contribute to major cellular processes. However, their potential role in HNSCC has not been studied systematically, which is the focus of this study. A total of 63 therapy-naive patients with squamous cell carcinoma were consecutively enrolled. Tissue microarray duplicate cores from each case were tested in situ for PKD1, PKD2, and PKD3 expression using immunohistochemistry, and the results were correlated with clinicopathological parameters. We found a high frequency of PKD1/PKD2 positive cases in oropharyngeal and PKD2 positive cases in laryngeal localizations. Only high PKD2 levels were statistically linked to elevated tumor grades, more advanced TNM (3–4) tumor stages, and p16INK4a expression, while elevated PKD3 levels were associated with favorable disease-specific survival. Both PKD2 and PKD3 have been proposed to promote tumor cell proliferation, migration/invasion, and angiogenesis. However, the role of PKD3 was elusive in some cancers. Our findings suggest that testing for PKD isotypes with immunohistochemistry may support the diagnostic estimation of tumor progression and prognosis in HNSCC with a potential therapeutic relevance.}, year = {2024}, eissn = {1422-0067}, orcid-numbers = {Gurbi, Bianka/0000-0002-5635-6255; Dános, Kornél/0000-0002-3829-8266; Birtalan, Ede/0000-0002-5699-3545; Krenács, Tibor/0000-0001-9164-065X; Kovács, Borbála/0000-0001-6864-6041; Tamás, László/0000-0003-3723-9149; Csala, Miklós/0000-0002-3829-4361} } @misc{MTMT:35202120, title = {Prevention of noise-induced hearing loss in children – recommendations for safe listening at events}, url = {https://m2.mtmt.hu/api/publication/35202120}, author = {Gáborján, Anita and Koscsó, Gábor and Garai, Réka and Tamás, László and Vicsi, Klára and Hacki, Tamás}, doi = {10.21203/rs.3.rs-4467179/v1}, unique-id = {35202120}, year = {2024}, orcid-numbers = {Tamás, László/0000-0003-3723-9149; Hacki, Tamás/0000-0001-9524-6748} } @article{MTMT:35162164, title = {Prognostic nutritional index (PNI) correlates with survival in head and neck cancer patients more precisely than other nutritional markers – real world data}, url = {https://m2.mtmt.hu/api/publication/35162164}, author = {Uri, Imre and Horváth, Angéla and Tamás, László and Polony, Gábor and Dános, Kornél}, doi = {10.1007/s00405-024-08865-w}, journal-iso = {EUR ARCH OTO-RHINO-L}, journal = {EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY}, volume = {online first}, unique-id = {35162164}, issn = {0937-4477}, abstract = {The survival benefit with higher body mass index (BMI) of patients suffering from head and neck squamous cell carcinoma (HNSCC) is documented as BMI paradox. As the early re-nourishment of high-risk patients determine survival, we searched for a nutritional status marker suitable for everyday screening. Grouping patients based on the 8th Edition of TNM Classification, we investigated for the first time the candidate nutritional status markers among TNM8 subgroups, including the newly introduced p16 positive oropharyngeal squamous cell cancer (OPSCC) patients.}, year = {2024}, eissn = {1434-4726}, orcid-numbers = {Tamás, László/0000-0003-3723-9149; Polony, Gábor/0000-0001-5236-8139; Dános, Kornél/0000-0002-3829-8266} } @article{MTMT:35078458, title = {Influencing Factors of Survival in Hypopharyngeal Squamous Cell Cancer}, url = {https://m2.mtmt.hu/api/publication/35078458}, author = {Répássy, Gábor Dénes (Ifj.) and Hargas, Dóra and Molnár, András and Maihoub, Stefani and Tamás, László}, doi = {10.3390/jcm13133853}, journal-iso = {J CLIN MED}, journal = {JOURNAL OF CLINICAL MEDICINE}, volume = {13}, unique-id = {35078458}, keywords = {p16 expression; chemotherapy‐; comorbidities; survival; Radiotherapy.; hypopharyngeal squamous cell cancer}, year = {2024}, eissn = {2077-0383}, orcid-numbers = {Répássy, Gábor Dénes (Ifj.)/0000-0002-9381-2272; Molnár, András/0000-0002-4417-5166; Tamás, László/0000-0003-3723-9149} } @article{MTMT:34919091, title = {Audiological outcomes after revision stapes surgeries: a systematic review}, url = {https://m2.mtmt.hu/api/publication/34919091}, author = {Székely, László Attila and Uri, Imre and Luka, Ágnes and Gáborján, Anita and Tamás, László and Polony, Gábor}, doi = {10.1007/s00405-024-08741-7}, journal-iso = {EUR ARCH OTO-RHINO-L}, journal = {EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY}, volume = {281}, unique-id = {34919091}, issn = {0937-4477}, year = {2024}, eissn = {1434-4726}, pages = {5051-5059}, orcid-numbers = {Tamás, László/0000-0003-3723-9149; Polony, Gábor/0000-0001-5236-8139} } @article{MTMT:34777714, title = {A társszakmák szoros együttműködésének szerepe a postmeningitises, súlyos fokú halláscsökkenés optimális és sikeres rehabilitációjában. Esettanulmány}, url = {https://m2.mtmt.hu/api/publication/34777714}, author = {Kecskeméti, Nóra and Kondé, Márton and Szigeti F., Judit and Baranyi, Ildikó and Paksi, Ádám and Küstel, Marianna and Polony, Gábor and Tamás, László and Barkóczi, Beáta and Lakatos, Lili and Horváth, Zsuzsanna and Gáborján, Anita}, journal-iso = {FÜL-ORR-GÉGEGYÓGYÁSZAT}, journal = {FÜL-ORR-GÉGEGYÓGYÁSZAT}, volume = {70}, unique-id = {34777714}, issn = {0016-237X}, year = {2024}, pages = {18-21}, orcid-numbers = {Kecskeméti, Nóra/0000-0003-1886-5021; Szigeti F., Judit/0000-0002-7155-6028; Küstel, Marianna/0000-0002-9920-1560; Polony, Gábor/0000-0001-5236-8139; Tamás, László/0000-0003-3723-9149; Lakatos, Lili/0000-0002-4888-4621} } @article{MTMT:34656287, title = {Characterization of middle ear microbiome in otitis media with effusion in Hungarian children: Alloiococcus otitidis may potentially hamper the microbial diversity}, url = {https://m2.mtmt.hu/api/publication/34656287}, author = {Fekete, Szilvia and Juhász, János and Makra, Nóra and Dunai, Zsuzsanna and Kristóf, Katalin and Ostorházi, Eszter and Tamás, László and Szabó, Dóra and Kecskeméti, Nóra and Polony, Gábor}, doi = {10.1016/j.heliyon.2024.e39380}, journal-iso = {HELIYON}, journal = {HELIYON}, volume = {10}, unique-id = {34656287}, year = {2024}, eissn = {2405-8440}, orcid-numbers = {Kristóf, Katalin/0000-0002-5189-4636; Ostorházi, Eszter/0000-0002-9459-7316; Tamás, László/0000-0003-3723-9149; Szabó, Dóra/0000-0002-8601-3923; Kecskeméti, Nóra/0000-0003-1886-5021; Polony, Gábor/0000-0001-5236-8139} } @{MTMT:34498331, title = {A légutak akut elzáródása}, url = {https://m2.mtmt.hu/api/publication/34498331}, author = {Tamás, László}, booktitle = {Sebészet tankönyv és tudománytörténet: traumatológiai, szülészeti és urológiai alapismeretekkel kiegészítve}, unique-id = {34498331}, year = {2023}, pages = {92-95}, orcid-numbers = {Tamás, László/0000-0003-3723-9149} }