@article{MTMT:3137194,
	title = {Effects of clary sage oil and its main components, linalool and linalyl acetate, on the plasma membrane of Candida albicans: an in vivo EPR study.},
	url = {https://m2.mtmt.hu/api/publication/3137194},
	author = {Blaskó, Ágnes and Gazdag, Zoltán and Gróf, Pál and Máté, Gábor and Tavaszi-Sárosi, Szilvia and Krisch, Judit and Vágvölgyi, Csaba and Makszin, Lilla and Pesti, Miklós},
	doi = {10.1007/s10495-016-1321-7},
	journal-iso = {APOPTOSIS},
	journal = {APOPTOSIS},
	volume = {22},
	unique-id = {3137194},
	issn = {1360-8185},
	abstract = {The effects of clary sage (Salvia sclarea L.) oil (CS-oil), and its two main components, linalool (Lol) and linalyl acetate (LA), on cells of the eukaryotic human pathogen yeast Candida albicans were studied. Dynamic and thermodynamic properties of the plasma membrane were investigated by electron paramagnetic resonance (EPR) spectroscopy, with 5-doxylstearic acid (5-SASL) and 16-SASL as spin labels. The monitoring of the head group regions with 5-SASL revealed break-point frequency decrease in a temperature dependent manner of the plasma membrane between 9.55 and 13.15 degrees C in untreated, in CS-oil-, Lol- and LA-treated membranes. The results suggest a significant increase in fluidity of the treated plasma membranes close to the head groups. Comparison of the results observed with the two spin labels demonstrated that CS-oil and LA induced an increased level of fluidization at both depths of the plasma membrane. Whereas Lol treatment induced a less (1 %) ordered bilayer organization in the superficial regions and an increased (10 %) order of the membrane leaflet in deeper layers. Acute toxicity tests and EPR results indicated that both the apoptotic and the effects exerted on the plasma membrane fluidity depended on the composition and chemical structure of the examined materials. In comparison with the control, treatment with CS-oil, Lol or LA induced 13.0, 12.3 and 26.4 % loss respectively, of the metabolites absorbing at 260 nm, as a biological consequence of the plasma membrane fluidizing effects. Our results confirmed that clary sage oil causes plasma membrane perturbations which leads to cell apoptosis process.},
	year = {2017},
	eissn = {1573-675X},
	pages = {175-187},
	orcid-numbers = {Gróf, Pál/0000-0002-6488-893X; Tavaszi-Sárosi, Szilvia/0000-0002-4646-6178; Krisch, Judit/0000-0002-6164-7794; Vágvölgyi, Csaba/0000-0003-0009-7773; Makszin, Lilla/0000-0002-9764-4763}
}

@article{MTMT:3075301,
	title = {Glucose transporter type 10 - lacking in arterial tortuosity syndrome - facilitates dehydroascorbic acid transport},
	url = {https://m2.mtmt.hu/api/publication/3075301},
	author = {Németh, Csilla Emese and Marcolongo, P and Gamberucci, A and Fulceri, R and Benedetti, A and Zoppi, N and Ritelli, M and Chiarelli, N and Colombi, M and Willaert, A and Callewaert, BL and Coucke, PJ and Gróf, Pál and Nagy, Szilvia Krisztina and Mészáros, Tamás and Bánhegyi, Gábor and Margittai, Éva},
	doi = {10.1002/1873-3468.12204},
	journal-iso = {FEBS LETT},
	journal = {FEBS LETTERS},
	volume = {590},
	unique-id = {3075301},
	issn = {0014-5793},
	abstract = {Loss-of-function mutations in the gene encoding GLUT10 are responsible for arterial tortuosity syndrome (ATS), a rare connective tissue disorder. In the present study GLUT10 mediated dehydroascorbic acid (DAA) transport was investigated, supposing its involvement in the pathomechanism. GLUT10 protein produced by in vitro translation and incorporated into liposomes efficiently transported DAA. Silencing of GLUT10 decreased DAA transport in immortalized human fibroblasts whose plasma membrane was selectively permeabilized. Similarly, the transport of DAA through endomembranes was markedly reduced in fibroblasts from ATS patients. Re-expression of GLUT10 in patients' fibroblasts restored DAA transport activity. The present results demonstrate that GLUT10 is a DAA transporter and DAA transport is diminished in the endomembranes of fibroblasts from ATS patients. This article is protected by copyright. All rights reserved.},
	year = {2016},
	eissn = {1873-3468},
	pages = {1630-1640},
	orcid-numbers = {Gróf, Pál/0000-0002-6488-893X; Nagy, Szilvia Krisztina/0000-0002-5505-1329; Mészáros, Tamás/0000-0002-7396-9678; Bánhegyi, Gábor/0000-0001-7559-0066; Margittai, Éva/0000-0003-0841-0613}
}

@article{MTMT:2914852,
	title = {FASCIN and alpha-actinin can regulate the conformation of actin filaments},
	url = {https://m2.mtmt.hu/api/publication/2914852},
	author = {Szeiliné Türmer, Katalin and Orbán, József and Gróf, Pál and Nyitrai, Miklós},
	doi = {10.1016/j.bbagen.2015.05.018},
	journal-iso = {BBA-GEN SUBJECTS},
	journal = {BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS},
	volume = {1850},
	unique-id = {2914852},
	issn = {0304-4165},
	year = {2015},
	eissn = {1872-8006},
	pages = {1855-1861},
	orcid-numbers = {Gróf, Pál/0000-0002-6488-893X; Nyitrai, Miklós/0000-0002-6229-4337}
}

@article{MTMT:2802362,
	title = {Extreme resilience in cochleate nanoparticles},
	url = {https://m2.mtmt.hu/api/publication/2802362},
	author = {Bozó, Tamás and Brecska, R and Gróf, Pál and Kellermayer, Miklós},
	doi = {10.1021/la504428x},
	journal-iso = {LANGMUIR},
	journal = {LANGMUIR},
	volume = {31},
	unique-id = {2802362},
	issn = {0743-7463},
	abstract = {Cochleates, prospective nanoscale drug delivery vehicles, are rolls of negatively-charged phospholipid membrane layers. The membrane layers are held together by calcium ions; however, neither the magnitude of membrane-interaction forces, nor the overall mechanical properties of cochleates have been known. Here we manipulated individual nanoparticles with atomic force microscopy to characterize their nanomechanical behavior. Their stiffness (4.2-12.5 N/m) and membrane-rupture forces (45.3-278 nN) are orders magnitude greater than those of the tough viral nanoshells. Even though the fundamental building material of cochleates is a fluid membrane, the combination of supramolecular geometry, the cross-linking action of calcium and the tight packing of the ions apparently lead to extreme mechanical resilience. The supramolecular design of cochleates may provide efficient protection for encapsulated materials and give clues to understanding biomolecular structures of similar design, such as the myelinated axon.},
	year = {2015},
	eissn = {1520-5827},
	pages = {839-845},
	orcid-numbers = {Bozó, Tamás/0000-0002-2643-0661; Gróf, Pál/0000-0002-6488-893X; Kellermayer, Miklós/0000-0002-5553-6553}
}

@CONFERENCE{MTMT:2794545,
	title = {Liposomesin pharmaceutical dosage forms and in cosmetics},
	url = {https://m2.mtmt.hu/api/publication/2794545},
	author = {Budai, Lívia and Budai, Marianna and Gróf, Pál and Nóra, Mike-Kaszás and Pápay, Zsófia Edit and Füredi, Petra and Noémi, Anna Niczinger and Antal, István},
	booktitle = {3rd International Conference on Nutraceutical and Cosmetic Sciences},
	unique-id = {2794545},
	year = {2014},
	pages = {24},
	orcid-numbers = {Budai, Lívia/0000-0002-6720-5989; Budai, Marianna/0000-0003-4947-9924; Gróf, Pál/0000-0002-6488-893X; Pápay, Zsófia Edit/0000-0002-7653-1065; Füredi, Petra/0000-0003-3618-8968; Antal, István/0000-0002-5434-201X}
}

@CONFERENCE{MTMT:2739141,
	title = {Membrán tekercsek morfológiája és mechanikai tulajdonságai},
	url = {https://m2.mtmt.hu/api/publication/2739141},
	author = {Bozó, Tamás and Brecska, R and Gróf, Pál and Kellerrmayer, MSZ},
	booktitle = {44. Membrán-transzport konferencia},
	unique-id = {2739141},
	year = {2014},
	pages = {35},
	orcid-numbers = {Bozó, Tamás/0000-0002-2643-0661; Gróf, Pál/0000-0002-6488-893X}
}

@article{MTMT:2578434,
	title = {Kohleát rendszerek előállítása, morfológiája és nanomechanikája},
	url = {https://m2.mtmt.hu/api/publication/2578434},
	author = {Bozó, Tamás and Brecska, Richárd and Gróf, Pál and Kellermayer, Miklós},
	journal-iso = {GYÓGYSZERÉSZET},
	journal = {GYÓGYSZERÉSZET},
	volume = {86},
	unique-id = {2578434},
	issn = {0017-6036},
	year = {2014},
	pages = {S104},
	orcid-numbers = {Bozó, Tamás/0000-0002-2643-0661; Gróf, Pál/0000-0002-6488-893X}
}

@article{MTMT:2506863,
	title = {Optical waveguide lightmode spectroscopic techniques for investigating membrane-bound ion channel activities.},
	url = {https://m2.mtmt.hu/api/publication/2506863},
	author = {Székács, Inna and Mike-Kaszás, Nóra and Gróf, Pál and Erdelyi, K and Szendro, I and Mihalik, Balázs and Pataki, A and Antoni, Ferenc András and Madarász, Emilia},
	doi = {10.1371/journal.pone.0081398},
	journal-iso = {PLOS ONE},
	journal = {PLOS ONE},
	volume = {8},
	unique-id = {2506863},
	issn = {1932-6203},
	abstract = {Optical waveguide lightmode spectroscopic (OWLS) techniques were probed for monitoring ion permeation through channels incorporated into artificial lipid environment. A novel sensor set-up was developed by depositing liposomes or cell-derived membrane fragments onto hydrophilic polytetrafluoroethylene (PTFE) membrane. The fibrous material of PTFE membrane could entrap lipoid vesicles and the water-filled pores provided environment for the hydrophilic domains of lipid-embedded proteins. The sensor surface was kept clean from the lipid holder PTFE membrane by a water- and ion-permeable polyethylene terephthalate (PET) mesh. The sensor set-up was tested with egg yolk lecithin liposomes containing gramicidin ion channels and with cell-derived membrane fragments enriched in GABA-gated anion channels. The method allowed monitoring the move of Na(+) and organic cations through gramicidin channels and detecting the Cl(-)-channel functions of the (alpha5beta2gamma2) GABAA receptor in the presence or absence of GABA and the competitive GABA-blocker bicuculline.},
	year = {2013},
	eissn = {1932-6203},
	orcid-numbers = {Mike-Kaszás, Nóra/0000-0002-7047-942X; Gróf, Pál/0000-0002-6488-893X; Mihalik, Balázs/0000-0002-4302-7567}
}

@article{MTMT:2461806,
	title = {Liposomes for topical use: physico-chemical comparison of vesicles prepared from egg or soy lecithin},
	url = {https://m2.mtmt.hu/api/publication/2461806},
	author = {Budai, Lívia and Mike-Kaszás, Nóra and Gróf, Pál and Földvári-Nagy Lászlóné Lenti, Katalin and Maghami, Katayoon and Antal, István and Klebovich, Imre and Petrikovics, Ilona and Budai, Marianna},
	doi = {10.3797/scipharm.1305-11},
	journal-iso = {SCI PHARM},
	journal = {SCIENTIA PHARMACEUTICA},
	volume = {81},
	unique-id = {2461806},
	issn = {0036-8709},
	year = {2013},
	eissn = {2218-0532},
	pages = {1151-1166},
	orcid-numbers = {Budai, Lívia/0000-0002-6720-5989; Mike-Kaszás, Nóra/0000-0002-7047-942X; Gróf, Pál/0000-0002-6488-893X; Földvári-Nagy Lászlóné Lenti, Katalin/0000-0002-1252-822X; Antal, István/0000-0002-5434-201X; Klebovich, Imre/0000-0003-1672-5172; Budai, Marianna/0000-0003-4947-9924}
}

@article{MTMT:2443105,
	title = {Interaction of formin FH2 with skeletal muscle actin. EPR and DSC studies},
	url = {https://m2.mtmt.hu/api/publication/2443105},
	author = {Kupi, Tünde and Gróf, Pál and Nyitrai, Miklós and Belágyi, József},
	doi = {10.1007/s00249-013-0922-0},
	journal-iso = {EUR BIOPHYS J},
	journal = {EUROPEAN BIOPHYSICS JOURNAL},
	volume = {42},
	unique-id = {2443105},
	issn = {0175-7571},
	year = {2013},
	eissn = {1432-1017},
	pages = {757-765},
	orcid-numbers = {Gróf, Pál/0000-0002-6488-893X; Nyitrai, Miklós/0000-0002-6229-4337}
}