@article{MTMT:35064218, title = {Validation of Constant Work Rate Cycling Endurance Time for Use in Chronic Obstructive Pulmonary Disease Clinical Trials}, url = {https://m2.mtmt.hu/api/publication/35064218}, author = {Casaburi, Richard and Merrill, Debora and Leidy, Nancy Kline and Locantore, Nicholas and Dolmage, Thomas and Garcia-Aymerich, Judith and Goldstein, Roger and Harding, Gale and Maltais, François and O’Donnell, Denis and Pórszász, János and Puente-Maestu, Luis and Rennard, Stephen and Rossiter, Harry B. and Sciurba, Frank and Spruit, Martijn A. and Tal-Singer, Ruth and Tetzlaff, Kay and van’t Hul, Alex and Yu, Ren and Hamilton, Alan}, doi = {10.1513/AnnalsATS.202305-480OC}, journal-iso = {ANN AM THORAC SOC}, journal = {ANNALS OF THE AMERICAN THORACIC SOCIETY}, volume = {21}, unique-id = {35064218}, issn = {2329-6933}, year = {2024}, eissn = {2325-6621}, pages = {727-739}, orcid-numbers = {Casaburi, Richard/0000-0002-8851-8589; Puente-Maestu, Luis/0000-0001-8501-0117; Tal-Singer, Ruth/0000-0002-5275-8062; van’t Hul, Alex/0000-0002-5514-2327} } @article{MTMT:35063993, title = {Reference equations for within-breath respiratory oscillometry in White adults}, url = {https://m2.mtmt.hu/api/publication/35063993}, author = {Veneroni, Chiara and Gobbi, Alessandro and Pompilio, Pasquale Pio and Dellacà, Raffaele and Fasola, Salvatore and La Grutta, Stefania and Leyva, Agustin and Pórszász, János and Stornelli, Silvia Romana and Fuso, Leonello and Valach, Christoph and Breyer-Kohansal, Robab and Breyer, Marie-Kathrin and Hartl, sylvia and Contu, Chiara and Inchingolo, Riccardo and Hodgdon, Kevin and Kaminsky, David A.}, doi = {10.1159/000539532}, journal-iso = {RESPIRATION}, journal = {RESPIRATION}, unique-id = {35063993}, issn = {0025-7931}, abstract = {Background: within-breath analysis of oscillometry parameters is a growing research area since it increases sensitivity and specificity to respiratory pathologies and conditions. However, reference equations for these parameters in White adults are lacking and devices using multiple sinusoids or pseudorandom forcing stimuli have been underrepresented in previous studies deriving reference equations. The current study aims to establish reference ranges for oscillometry parameters, including also the within-breath ones in White adults using multi-sinusoidal oscillations.Methods: White adults with normal spirometry, BMI≤30kg/m2, without a smoking history, respiratory symptoms, pulmonary or cardiac disease, neurological or neuromuscular disorders, and respiratory tract infections in the previous 4 weeks were eligible for the study. Study subjects underwent oscillometry (multifrequency waveform at 5-11-19Hz, Resmon PRO FULL, Restech Srl, Italy) in 5 centers in Europe and the USA according to international standards. The within-breath and total resistance (R) and reactance (X), the resonance frequency, the area under the X curve, the frequency dependence of R (R5-19), and within-breath changes of X (ΔX) were submitted to Lambda-Mu-Sigma models for deriving reference equations. For each output parameter, an AIC-based stepwise input variable selection procedure was applied. Results: 144 subjects (age 20.8 – 86.3 years; height 146 – 193 cm; BMI 17.42 – 29.98 kg/m2; 56% females) were included. We derived reference equations for 29 oscillatory parameters. Predicted values for inspiratory and expiratory parameters were similar, while differences were observed for their limits of normality.Conclusions: We derived reference equations with narrow confidence intervals for within‐breath and whole‐breath oscillatory parameters for White adults.}, year = {2024}, eissn = {1423-0356} } @article{MTMT:34638339, title = {Beyond Spirometry: Linking Wasted Ventilation to Exertional Dyspnea in the Initial Stages of COPD}, url = {https://m2.mtmt.hu/api/publication/34638339}, author = {Neder, J. Alberto and Santyr, Giles and Zanette, Brandon and Kirby, Miranda and Pourafkari, Marina and James, Matthew D. and Vincent, Sandra G. and Ferguson, Carrie and Wang, Chu-Yi and Domnik, Nicolle J. and Phillips, Devin B. and Pórszász, János and Stringer, William W. and O’Donnell, Denis E.}, doi = {10.1080/15412555.2023.2301549}, journal-iso = {COPD}, journal = {COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE}, volume = {21}, unique-id = {34638339}, issn = {1541-2555}, year = {2024}, eissn = {1541-2563} } @article{MTMT:34354451, title = {Lack of effect of an in-line filter on cardiopulmonary exercise testing variables in healthy subjects}, url = {https://m2.mtmt.hu/api/publication/34354451}, author = {Abbasi, Asghar and Ahmad, Khadije and Ferguson, Carrie and Soriano, April and Calmelat, Robert and Rossiter, Harry B. and Casaburi, Richard and Stringer, William W. and Pórszász, János}, doi = {10.1007/s00421-023-05327-9}, journal-iso = {EUR J APPL PHYSIOL}, journal = {EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY}, volume = {124}, unique-id = {34354451}, issn = {1439-6319}, abstract = {Purpose Pathogen transmission during cardio-pulmonary exercise testing (CPET) is caused by carrier aerosols generated during respiration.Methods Ten healthy volunteers (age range: 34 +/- 15; 4 females) were recruited to see if the physiological reactions to ramp incremental CPET on a cycle ergometer were affected using an in-line filter placed between the mouthpiece and the flow sensor. The tests were in random order with or without an in-line bacterial/viral spirometer filter. The work rate aligned, time interpolated 10 s bin data were compared throughout the exercise period.Results From rest to peak exercise, filter use increased only minute ventilation ( V-E) (Delta V-E= 1.56 +/- 0.70 L/min, P < 0.001) and tidal volume (V-T) (Delta V-T = 0.10 +/- 0.11 L, P = 0.014). Over the entire test, the slope of the residuals for VCO2 was positive (0.035 +/- 0.041 (Delta L/L), P = 0.027). During a ramp-incremental CPET in healthy subjects, an in-line filter increased V-E and V-T but not metabolic rate.Conclusion In conclusion, using an in-line filter is feasible, does not affect appreciably the physiological variables, and may mitigate risk of aerosol dispersion during CPET.}, keywords = {Ventilation; Cardiopulmonary exercise testing; respiratory viruses; COVID-19; In-line filter; Aerosol-generating procedures}, year = {2024}, eissn = {1439-6327}, pages = {1027-1036} } @article{MTMT:35064015, title = {A Hybrid Effectiveness/Implementation Clinical Trial of Adherence to Long-Term Oxygen Therapy for Chronic Obstructive Pulmonary Disease}, url = {https://m2.mtmt.hu/api/publication/35064015}, author = {Prieto-Centurion, Valentin and Holm, Kristen E. and Casaburi, Richard and Pórszász, János and Basu, Sanjib and Bracken, Nina E. and Gallardo, Richard and Gonzalez, Vanessa and Illendula, Sai D. and Sandhaus, Robert A. and Sullivan, Jamie L. and Walsh, Linda J. and Gerald, Lynn B. and Krishnan, Jerry A.}, doi = {10.1513/AnnalsATS.202302-104OC}, journal-iso = {ANN AM THORAC SOC}, journal = {ANNALS OF THE AMERICAN THORACIC SOCIETY}, volume = {20}, unique-id = {35064015}, issn = {2329-6933}, year = {2023}, eissn = {2325-6621}, pages = {1561-1570}, orcid-numbers = {Gerald, Lynn B./0000-0002-7279-0051; Krishnan, Jerry A./0000-0001-5525-4778} } @article{MTMT:35063994, title = {Critical Power and Respiratory Compensation Point Are Not Equivalent in Patients with COPD}, url = {https://m2.mtmt.hu/api/publication/35063994}, author = {TILLER, NICHOLAS B. and Pórszász, János and CASABURI, RICHARD and ROSSITER, HARRY B. and FERGUSON, CARRIE}, doi = {10.1249/MSS.0000000000003124}, journal-iso = {MED SCI SPORT EXER}, journal = {MEDICINE AND SCIENCE IN SPORTS AND EXERCISE}, volume = {55}, unique-id = {35063994}, issn = {0195-9131}, year = {2023}, eissn = {1530-0315}, pages = {1097-1104} } @article{MTMT:35063989, title = {Diffusing Capacity and Mortality in Chronic Obstructive Pulmonary Disease}, url = {https://m2.mtmt.hu/api/publication/35063989}, author = {Balasubramanian, Aparna and Putcha, Nirupama and MacIntyre, Neil R. and Jensen, Robert L. and Kinney, Gregory and Stringer, William W. and Hersh, Craig P. and Bowler, Russell P. and Casaburi, Richard and Han, MeiLan K. and Pórszász, János and Barr, R. Graham and Regan, Elizabeth and Make, Barry J. and Hansel, Nadia N. and Wise, Robert A. and McCormack, Meredith C.}, doi = {10.1513/AnnalsATS.202203-226OC}, journal-iso = {ANN AM THORAC SOC}, journal = {ANNALS OF THE AMERICAN THORACIC SOCIETY}, volume = {20}, unique-id = {35063989}, issn = {2329-6933}, year = {2023}, eissn = {2325-6621}, pages = {38-46}, orcid-numbers = {Hersh, Craig P./0000-0002-1342-4334; Wise, Robert A./0000-0002-8353-2349; McCormack, Meredith C./0000-0003-1702-3201} } @article{MTMT:35063988, title = {Evaluation of Over-the-Counter Portable Oxygen Concentrators Utilizing a Metabolic Simulator}, url = {https://m2.mtmt.hu/api/publication/35063988}, author = {Casaburi, Richard and Hess, Michael and Pórszász, János and Clark, William and Diesem, Ryan and Tal-Singer, Ruth and Ferguson, Carrie}, doi = {10.4187/respcare.10495}, journal-iso = {RESP CARE}, journal = {RESPIRATORY CARE}, volume = {68}, unique-id = {35063988}, issn = {0020-1324}, year = {2023}, eissn = {1943-3654}, pages = {445-451} } @article{MTMT:35063695, title = {Response}, url = {https://m2.mtmt.hu/api/publication/35063695}, author = {FERGUSON, CARRIE and TILLER, NICHOLAS B. and Pórszász, János and CASABURI, RICHARD and ROSSITER, HARRY B.}, doi = {10.1249/MSS.0000000000003211}, journal-iso = {MED SCI SPORT EXER}, journal = {MEDICINE AND SCIENCE IN SPORTS AND EXERCISE}, volume = {55}, unique-id = {35063695}, issn = {0195-9131}, year = {2023}, eissn = {1530-0315}, pages = {1941-1941} } @article{MTMT:34298821, title = {Letter to the editor in response to Hoskote "Corrected formula for rectangular area ratio (RAR), a parameter used to quantify airflow limitation on expiratory flow-volume curves" Respiratory Medicine 2022; 204: 107032}, url = {https://m2.mtmt.hu/api/publication/34298821}, author = {Pórszász, János and Wang, Chu-Yi and Ferguson, Carrie and Ma, Shuyi and Girardi, Michele and Stringer, William W.}, doi = {10.1016/j.rmed.2023.107304}, journal-iso = {RESP MED}, journal = {RESPIRATORY MEDICINE}, volume = {215}, unique-id = {34298821}, issn = {0954-6111}, year = {2023}, eissn = {1532-3064}, orcid-numbers = {Ma, Shuyi/0000-0003-0783-1328; Girardi, Michele/0000-0001-8102-7384} }