@article{MTMT:33131836,
	title = {The role of urinary N-acetyl-beta-D-glucosaminidase in early detection of acute kidney injury among pediatric patients with neoplastic disorders in a retrospective study},
	url = {https://m2.mtmt.hu/api/publication/33131836},
	author = {Biró, Erika and Szegedi, István and Kiss, Csongor and Vargáné Oláh, Anna and Dockrell, Mark and Price, Robert G. and Szabó, Tamás},
	doi = {10.1186/s12887-022-03416-w},
	journal-iso = {BMC PEDIATR},
	journal = {BMC PEDIATRICS},
	volume = {22},
	unique-id = {33131836},
	issn = {1471-2431},
	abstract = {Background: The 1-year cumulative incidence of AKI reportedly is high (52%) in pediatric neoplastic disorders. About half of these events occur within 2 weeks. However, subclinical AKI episodes may remain unrecognized by the conventional creatinine-based approaches. We investigated the diagnostic value of urinary N-acetyl-beta-D-glucosaminidase (uNAG) as an early marker of acute kidney injury (AKI). Methods: In our retrospective study, 33 children with neoplastic disorders were inculded who had serial uNAG tests (at least 5 samples/patient) with a total of 367 uNAG measurements. Renal function was determined by cystatin-C and creatinine based GFR, and relative increase of uNAG index -(uNAG(RI)). We focused on detecting both clinical and subclinical AKI episodes (according to Biomarker-Guided Risk Assessment using pRIFLE criteria and /or elevated uNAG levels) and the incidence of chronic kidney damage. Results: Sixty episodes in 26 patients, with positivity at least in one parameter of kidney panel, were identified during the observation period. We detected 18/60 clinical and 12/60 subclinical renal episodes. In 27/60 episodes only uNAG values was elevated with no therapeutic consequence at presentation. Two patients were detected with decreased initial creatinine levels with 3”silent” AKI. In 13 patients, modest elevation of uNAG persisted suggesting mild, reversible tubular damage, while chronic tubuloglomerular injury occurred in 5 patients. Based on ROC analysis for the occurence of AKI, uNAG(RI) significantly indicated the presence of AKI, the sensitivity and specificity are higher than the changes of -GFR(Creat). Serial uNAG measurements are recommended for the reduction of the great amount of false positive uNAG results, often due to overhydratation. Conclusion: Use of Biomarker-guided Risk Assessment for AKI identified 1.5 x more clinical and subclinical AKI episodes than with creatinine alone in our pediatric cancer patients. Based on the ROC curve for the occurence of AKI, uNAG(RI) has relatively high sensitivity and specificity comparable to changes of GFR(CysC). The advantage of serial uNAG measurements is to decrease the number of false positive results.},
	year = {2022},
	eissn = {1471-2431}
}

@article{MTMT:31892935,
	title = {Detection of haemolysis, a frequent preanalytical problem in the serum of newborns and adults.},
	url = {https://m2.mtmt.hu/api/publication/31892935},
	author = {Tóth, Judit and Vargáné Oláh, Anna and Petercsák, Tamás and Kovács, Tamás and Kappelmayer, János},
	journal-iso = {E JIFCC},
	journal = {ELECTRONIC JOURNAL OF THE INTERNATIONAL FEDERATION OF CLINICAL CHEMISTRY AND LABORATORY MEDICINE},
	volume = {31},
	unique-id = {31892935},
	issn = {1650-3414},
	abstract = {Preanalytical problems can be more frequent in case of preterm and term newborns as compared to the general patient population. Here we present the leading preanalytical errors in our laboratory, the prevalence of haemolysis and its impact on laboratory test results, and our efforts to improve the diagnostic workup of newborns' samples.Preanalytical quality indicators were analysed in all samples in 2018. The haemolysis index was measured spectrophotometrically in serum samples in the period of 2012-2018, and the ratio of haemolysed samples and the test rejection rates were analysed. The data of newborns and other patients were analysed separately.During the tested year, the leading preanalytical errors were haemolysis in serum samples, inadequate sample identification and clotting of anticoagulated blood regarding all samples or newborns. In this seven-year period the ratio of haemolysed serum samples was 4.00% in all patients and 46.4% in newborns, while the test rejection rates due to haemolysis were 0.57% and 3.71%, respectively. Haemolysis indices were significantly higher in case of newborns than in patients with documented severe intravascular haemolysis which suggests that the major reason of elevated haemolysis indices in newborns was in vitro haemolysis. Accordingly, all C-reactive protein (CRP) results which were rejected by severe haemolysis became reliable after repeating blood sampling.Haemolysis is the leading preanalytical problem not only in newborns but also in the general patient population. Our study highlights the importance of automated assessment of serum indices and continuous monitoring of the preanalytical quality indicators and suggests the need for education and blood collection trainings.},
	keywords = {Reproducibility of Results; Specimen Handling; total quality management; Blood Chemical Analysis; Clinical Laboratory Techniques},
	year = {2020},
	pages = {6-14}
}

@article{MTMT:31332668,
	title = {Transglutaminase 2 Has Metabolic and Vascular Regulatory Functions Revealed by In Vivo Activation of Alpha1-Adrenergic Receptor},
	url = {https://m2.mtmt.hu/api/publication/31332668},
	author = {Lénárt, Kinga and Pap, Attila and Pórszász, Róbert and Vargáné Oláh, Anna and Fésüs, László and Mádi, András},
	doi = {10.3390/ijms21113865},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {21},
	unique-id = {31332668},
	issn = {1661-6596},
	year = {2020},
	eissn = {1422-0067}
}

@article{MTMT:31143304,
	title = {Intracardiac Fibrinolysis and Endothelium Activation Related to Atrial Fibrillation Ablation with Different Techniques},
	url = {https://m2.mtmt.hu/api/publication/31143304},
	author = {Hajas, Orsolya and Bagoly, Zsuzsa and Tóth, Noémi Klára and Urbancsek, Réka and Kiss, Alexandra and Kovács, Kitti Bernadett and Sarkady, Ferenc and Nagy, Attila Csaba and Vargáné Oláh, Anna and Nagy, László Tibor and Clemens, Marcell and Csiba, László and Csanádi, Zoltán},
	doi = {10.1155/2020/1570483},
	journal-iso = {CARDIOL RES PRAC},
	journal = {CARDIOLOGY RESEARCH AND PRACTICE},
	volume = {2020},
	unique-id = {31143304},
	issn = {2090-0597},
	year = {2020},
	eissn = {2090-8016},
	orcid-numbers = {Bagoly, Zsuzsa/0000-0001-5314-5607; Kovács, Kitti Bernadett/0000-0003-1781-2390; Nagy, Attila Csaba/0000-0002-0554-7350}
}

@article{MTMT:3289057,
	title = {Browning deficiency and low mobilization of fatty acids in gonadal white adipose tissue leads to decreased cold-tolerance of transglutaminase 2 knock-out mice.},
	url = {https://m2.mtmt.hu/api/publication/3289057},
	author = {Mádi, András and Cuaranta-Monroy, I and Lénárt, Kinga and Pap, Attila and Mezei, Zoltán András and Kristóf, Endre and Vargáné Oláh, Anna and Vámosi, György and Bacso, Z and Bay, Péter and Fésüs, László},
	doi = {10.1016/j.bbalip.2017.07.014},
	journal-iso = {BBA-MOL CELL BIOL L},
	journal = {BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS},
	volume = {1862},
	unique-id = {3289057},
	issn = {1388-1981},
	abstract = {During cold-exposure 'beige' adipocytes with increased mitochondrial content are activated in white adipose tissue (WAT). These cells, similarly to brown adipose tissue (BAT), dissipate stored chemical energy in the form of heat with the help of uncoupling protein 1 (UCP1). We investigated the effect of tissue transglutaminase (TG2) ablation on the function of ATs in mice. Although TG2+/+ and TG2-/- mice had the same amount of WAT and BAT, we found that TG2+/+ animals could tolerate acute cold exposure for 4h, whereas TG2-/- mice only for 3h. Both TG2-/- and TG2+/+ animals used up half of the triacylglycerol content of subcutaneous WAT (SCAT) after 3h treatment; however, TG2-/- mice still possessed markedly whiter and higher amount of gonadal WAT (GONAT) as reflected in the larger size of adipocytes and lower free fatty acid levels in serum. Furthermore, lower expression of 'beige' marker genes such as UCP1, TBX1 and TNFRFS9 was observed after cold exposure in GONAT of TG2-/- mice, paralleled with a lower level of UCP1 protein and a decreased mitochondrial content. The detected changes in gene expression of Resistin and Adiponectin did not provoke glucose intolerance in the investigated TG2-/- mice, and TG2 deletion did not influence adrenaline, noradrenaline, glucagon and insulin production. Our data suggest that TG2 has a tissue-specific role in GONAT function and browning, which becomes apparent under acute cold exposure.},
	year = {2017},
	eissn = {1879-2618},
	pages = {1575-1586},
	orcid-numbers = {Mezei, Zoltán András/0000-0002-7886-8665; Kristóf, Endre/0000-0002-2215-6984}
}

@article{MTMT:3188640,
	title = {High Sensitive Troponin T has an Incremental Value in Estimation of Cardiovascular Risk in Chronic Kidney Disease.},
	url = {https://m2.mtmt.hu/api/publication/3188640},
	author = {Vargáné Oláh, Anna and Szalka, T and Szantha, E and Varga, Éva and Mátyus, János and Varga, József},
	journal-iso = {J NEPHROL THERAP},
	journal = {JOURNAL OF NEPHROLOGY AND THERAPEUTICS},
	volume = {3},
	unique-id = {3188640},
	issn = {2161-0959},
	year = {2017},
	pages = {1-6},
	orcid-numbers = {Varga, Éva/0000-0003-2716-0541}
}

@article{MTMT:3178666,
	title = {Comparative erythrocyte deformability investigations by filtrometry, slit-flow and rotational ektacytometry in a long-term follow-up animal study on splenectomy and different spleen preserving operative techniques. Partial or subtotal spleen resection and spleen autotransplantation},
	url = {https://m2.mtmt.hu/api/publication/3178666},
	author = {Mikó, Irén and Németh, Norbert and Somogyi, Viktória and Kiss, F and Toth, E and Pető, Katalin and Furka, Andrea and Ványolos, Erzsébet and Tóth, László József and Varga, József and Szigeti, Krisztián and Benkő, Ilona and Vargáné Oláh, Anna and Furka, István},
	doi = {10.3233/CH-160231},
	journal-iso = {CLIN HEMORHEOL MICRO},
	journal = {CLINICAL HEMORHEOLOGY AND MICROCIRCULATION},
	volume = {66},
	unique-id = {3178666},
	issn = {1386-0291},
	year = {2017},
	eissn = {1875-8622},
	pages = {83-96},
	orcid-numbers = {Németh, Norbert/0000-0002-1162-3778; Ványolos, Erzsébet/0000-0002-5483-0275}
}

@{MTMT:3194060,
	title = {Autovalidation in laboratory medicine, clinical chemistry. Register of laboratory examinations},
	url = {https://m2.mtmt.hu/api/publication/3194060},
	author = {Vargáné Oláh, Anna and Bhattoa Harjit, Pál},
	booktitle = {Az élettudományi - klinikai felsőoktatás gyakorlatorientált és hallgatóbarát korszerűsítése a vidéki képzőhelyek nemzetközi versenyképességének erősítésére.},
	unique-id = {3194060},
	year = {2015},
	pages = {1-31},
	orcid-numbers = {Bhattoa Harjit, Pál/0000-0002-4909-0065}
}

@article{MTMT:3069497,
	title = {Change of leukocyte antisedimentation rate and other hematological and hemorheological parameters in beagle dogs with splenectomy and different amount of residual spleen after the mandatory vaccination},
	url = {https://m2.mtmt.hu/api/publication/3069497},
	author = {Mikó, Irén and Tóth, E and Kiss, F and Furka, István and Pető, Katalin and Furka, Andrea and Deák, Ádám and Ványolos, Erzsébet and Vargáné Oláh, Anna and Tóth, L and Benkő, I and Németh, Norbert},
	doi = {10.1159/000381839},
	journal-iso = {EUR SURG RES},
	journal = {EUROPEAN SURGICAL RESEARCH},
	volume = {55},
	unique-id = {3069497},
	issn = {0014-312X},
	year = {2015},
	eissn = {1421-9921},
	pages = {158-159},
	orcid-numbers = {Ványolos, Erzsébet/0000-0002-5483-0275; Németh, Norbert/0000-0002-1162-3778}
}

@article{MTMT:3029072,
	title = {A veleszületett koleszterinhiány jellemző biomarkerei Smith-Lemli-opitz-szindrómás betegekben és hordozókban},
	url = {https://m2.mtmt.hu/api/publication/3029072},
	author = {Vargáné Oláh, Anna and P, Szabó Gabriella and Varga, József and Koczok, Katalin and Balogh, István and Harangi, János},
	journal-iso = {METABOLIZMUS},
	journal = {METABOLIZMUS},
	volume = {13},
	unique-id = {3029072},
	issn = {1589-7311},
	year = {2015},
	pages = {196-201}
}