TY - JOUR AU - Háznagyné Radnai, Erzsébet AU - Czigle, Sz. AU - Máthé, Imre TI - Iridoids from Stachys byzantina K. Koch (Lamb's Ears) and Stachys germanica L. (Downy Woundwort) JF - EUROPEAN PHARMACEUTICAL JOURNAL J2 - Eur Pharmaceu J VL - 68 PY - 2021 IS - 1 SP - 54 EP - 58 PG - 5 SN - 2453-6725 DO - 10.2478/afpuc-2020-0024 UR - https://m2.mtmt.hu/api/publication/32575411 ID - 32575411 LA - English DB - MTMT ER - TY - JOUR AU - Czigle, Szilvia AU - Héthelyi B, Éva AU - Háznagyné Radnai, Erzsébet AU - Máthé, Imre AU - Tóth, Jaroslav TI - Analysis of Volatile Constituents of Ginkgo Leaf JF - NATURAL PRODUCT COMMUNICATIONS J2 - NAT PROD COMMUN VL - 14 PY - 2019 IS - 6 SP - 1 EP - 8 PG - 8 SN - 1934-578X DO - 10.1177/1934578X19857900 UR - https://m2.mtmt.hu/api/publication/30742592 ID - 30742592 LA - English DB - MTMT ER - TY - JOUR AU - Csupor, Dezső AU - Micsinay, Ákos AU - Máthé, Imre AU - Horváth-Boros, Klára AU - Kiss, Tivadar AU - Hohmann, Judit TI - Planar chromatography in the quality control of adulterated Citrus paradisi seed extract-containing products JF - JPC - JOURNAL OF PLANAR CHROMATOGRAPHY - MODERN TLC J2 - J PLANAR CHROMATOGR MOD TLC VL - 31 PY - 2018 IS - 1 SP - 23 EP - 27 PG - 5 SN - 0933-4173 DO - 10.1556/1006.2018.31.1.3 UR - https://m2.mtmt.hu/api/publication/3319150 ID - 3319150 AB - Grapefruit (Citrus paradisi) seeds are increasingly applied for medicinal purposes, especially due to their antimicrobial and immunostimulant features, to treat or prevent common cold. However, the scientific background of these uses has not been established. To date, only in vitro studies support the antimicrobial effect of the seeds, and there are no data on the systemic antibiotic or other clinical effects. Moreover, recent data refer to the adulteration of grapefruit seed products with synthetic antiseptics which may be an explanation for the antimicrobial efficacy of some formulations. The aim of our study was to develop a simple thin-layer chromatography- based method for the quality control of grapefruit seed extracts. Besides the analytical procedure, we report a quick and simple method for the isolation of limonoids from grapefruit seeds. Limonoids are characteristic compounds of the seeds; hence, the detection of these marker compounds may be the basis of grapefruit identification. Further, a thin-layer chromatographic screening for synthetic antiseptics (quaternary ammonium salts) is also part of the quality control procedure. LA - English DB - MTMT ER - TY - CHAP AU - Máthé, Imre ED - Máthé, Ákos TI - Chemical Diversity of Medicinal Plants T2 - Medicinal and Aromatic Plants of the World 1. PB - Springer-Verlag Wien CY - New York, New York CY - London CY - Dordrecht CY - Heidelberg SN - 9789401798099 T3 - Medicinal and Aromatic Plants of the World PY - 2015 SP - 35 EP - 60 PG - 26 DO - 10.1007/978-94-017-9810-5_3 UR - https://m2.mtmt.hu/api/publication/3012237 ID - 3012237 LA - English DB - MTMT ER - TY - JOUR AU - Hajdú, Zsuzsanna AU - Zana, Ágnes AU - Jedlinszki, Nikoletta AU - Máthé, Imre AU - Dombi, G AU - Hohmann, Judit TI - Chemical constituents of Artemisia asiatica roots JF - PLANTA MEDICA: NATURAL PRODUCTS AND MEDICINAL PLANT RESEARCH J2 - PLANTA MED VL - 81 PY - 2015 IS - 16 PG - 1 SN - 0032-0943 DO - 10.1055/s-0035-1565429 UR - https://m2.mtmt.hu/api/publication/2977485 ID - 2977485 LA - English DB - MTMT ER - TY - JOUR AU - Engel, Rita AU - Veres, Katalin AU - Hajdú, Zsuzsanna AU - Szabó, K AU - Blunden, G AU - Hohmann, Judit AU - Máthé, Imre TI - Annual variation of the essential oil production of Artemisia asiatica JF - PLANTA MEDICA: NATURAL PRODUCTS AND MEDICINAL PLANT RESEARCH J2 - PLANTA MED VL - 81 PY - 2015 IS - 16 PG - 1 SN - 0032-0943 DO - 10.1055/s-0035-1565844 UR - https://m2.mtmt.hu/api/publication/2977483 ID - 2977483 LA - English DB - MTMT ER - TY - JOUR AU - Zana, Annamária AU - Hajdú, Zsuzsanna AU - Jedlinszki, Nikoletta AU - Máthé, Imre AU - Dombi, György AU - Hohmann, Judit TI - Isolation and structural determination of new metabolites from Artemisia asiatica roots JF - TETRAHEDRON J2 - TETRAHEDRON VL - 71 PY - 2015 IS - 29 SP - 4817 EP - 4820 PG - 4 SN - 0040-4020 DO - 10.1016/j.tet.2015.05.033 UR - https://m2.mtmt.hu/api/publication/2904138 ID - 2904138 AB - Abstract Two new 2,2-dimethyl-chromene derivatives and the new pentaisovaleryl sucrose were isolated from the roots of Artemisia asiatica together with the known 1-(5-acetyl-2,4-dihydroxy-phenyl)-3-methyl-butan-1-one, 6-hydroxytremetone and (E)-coniferyl aldehyde. The structures of the compounds were elucidated by extensive 1D (1H, 13C and JMOD) and 2D (1H–1H COSY, HSQC, HMBC and NOESY) NMR studies and APCIMS and HRESIMS investigations. 6-Acetyl-3,7-dihydroxy-2,2-dimethyl-chromene and 6-acetyl-3-hydroxy-2,2-dimethyl-chromene are biogenetically related to 1-(5-acetyl-2,4-dihydroxy-phenyl)-3-methyl-butan-1-one and 6-hydroxytremetone as all having isoprenoid acetophenone origin. All the isolated compounds were described for the first time from this species; interestingly none of them are related to the metabolites identified from the extracts of the aerial part of the plant. LA - English DB - MTMT ER - TY - JOUR AU - Könczöl, Árpád AU - Engel, Rita AU - Szabó, K AU - Hornok, K AU - Tóth, S AU - Béni, Zoltán AU - Prechl, A AU - Máthé, Imre AU - Balogh, György Tibor TI - Topical analgesic, anti-inflammatory and antioxidant properties of Oxybaphus nyctagineus: Phytochemical characterization of active fractions JF - JOURNAL OF ETHNOPHARMACOLOGY J2 - J ETHNOPHARMACOL VL - 155 PY - 2014 IS - 1 SP - 776 EP - 784 PG - 9 SN - 0378-8741 DO - 10.1016/j.jep.2014.06.020 UR - https://m2.mtmt.hu/api/publication/2781164 ID - 2781164 N1 - WoS:hiba:000340854000080 2019-03-09 22:44 első szerző nem egyezik AB - Ethnopharmacological relevance Oxybaphus nyctagineus (Michx.) Sweet has traditionally been used by several Native American tribes predominantly as a topical anti-inflammatory and analgesic agent. Aim of the study To evaluate the antioxidant, analgesic and anti-inflammatory activity of the extracts prepared from the aerial parts of Oxybaphus nyctagineus and to characterize the major chemical constituents of the bioactive extracts. Materials and methods Crude polar and apolar extracts (PCE and ACE) of the herb of Oxybaphus nyctagineus were prepared and tested in the models of the CFA-induced hyperalgesia in rat knee and carrageenan-induced paw edema in rat. To identify the active compounds, subfractions were prepared by column chromatography and subjected in vitro assays, such as antioxidant assays (DPPH, peroxynitrite (ONOO-) scavenging), and the LPS-induced IL-1β release test in human monocytes. Preparative HPLC was employed for the isolation of active substances, while phytochemical analysis was performed by mean of LC-MS/MS and NMR. Results The topically administered PCE and ACE of Oxybaphus nyctagineus demonstrated a significant analgesic and anti-inflammatory effect in the inflammation animal models. The subfraction A4 of ACE and the subfraction P5 of PCE considerably inhibited the LPS-induced IL-1β release in human monocytes, while the strongest activity was localized in the subfraction P5 in the antioxidant assays. The HPLC-MS/MS and NMR analysis revealed that 6-methoxyflavonol diglycosides, namely patuletin-3-O-robinobioside (1), 6-methoxykaempferol-3-O- robinobioside (2), spinacetin-3-O-robinobioside (3), and hydroxy-polyenoic fatty acids, namely corchorifatty acid B (4), 9-hydroxy-10E,12Z,15Z-octadecatrienoic acid (9-HOT acid) (5), and 9-hydroxy-10E,12Z-octadecadienoic acid (9-HOD acid) (6) were present in PCE, and in ACE as major compounds. Conclusion The results of this study established a pharmacological evidence for the traditional use of Oxybaphus nyctagineus as an anti-inflammatory agent used topically, and provided data on its phytochemical composition for the first time. © 2014 Elsevier Ireland Ltd. All rights reserved. LA - English DB - MTMT ER - TY - JOUR AU - Hajdú, Zsuzsanna AU - Hohmann, Judit AU - Forgó, Péter AU - Máthé, Imre AU - Molnár, J AU - Zupkó, István TI - Antiproliferative activity of Artemisia asiatica cultivated in Central Europe JF - PLANTA MEDICA: NATURAL PRODUCTS AND MEDICINAL PLANT RESEARCH J2 - PLANTA MED VL - 80 PY - 2014 IS - 16 SP - 1492 EP - 1492 PG - 1 SN - 0032-0943 DO - 10.1055/s-0034-1394907 UR - https://m2.mtmt.hu/api/publication/2768295 ID - 2768295 LA - English DB - MTMT ER - TY - JOUR AU - Hajdú, Zsuzsanna AU - Hohmann, Judit AU - Forgó, Péter AU - Máthé, Imre AU - Molnár, Judit AU - Zupkó, István TI - Antiproliferative Activity of Artemisia asiatica Extract and Its Constituents on Human Tumor Cell Lines JF - PLANTA MEDICA: NATURAL PRODUCTS AND MEDICINAL PLANT RESEARCH J2 - PLANTA MED VL - 80 PY - 2014 IS - 18 SP - 1692 EP - 1697 PG - 6 SN - 0032-0943 DO - 10.1055/s-0034-1383146 UR - https://m2.mtmt.hu/api/publication/2753693 ID - 2753693 N1 - Institute of Pharmacognosy, University of Szeged, Eotvos u. 6, Szeged, 6720, Hungary Institute of Ecology and Botany, Centre for Ecological Research, Hungarian Academy of Sciences, Vácrátót, Hungary Institute of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Hungary Cited By :15 Export Date: 27 April 2021 CODEN: PLMEA Correspondence Address: Hohmann, J.; Institute of Pharmacognosy, University of Szeged, Eotvos u. 6, Hungary LA - English DB - MTMT ER -