@article{MTMT:32575411, title = {Iridoids from Stachys byzantina K. Koch (Lamb's Ears) and Stachys germanica L. (Downy Woundwort)}, url = {https://m2.mtmt.hu/api/publication/32575411}, author = {Háznagyné Radnai, Erzsébet and Czigle, Sz. and Máthé, Imre}, doi = {10.2478/afpuc-2020-0024}, journal-iso = {Eur Pharmaceu J}, journal = {EUROPEAN PHARMACEUTICAL JOURNAL}, volume = {68}, unique-id = {32575411}, year = {2021}, eissn = {2453-6725}, pages = {54-58}, orcid-numbers = {Háznagyné Radnai, Erzsébet/0000-0003-4034-5989} } @article{MTMT:30742592, title = {Analysis of Volatile Constituents of Ginkgo Leaf}, url = {https://m2.mtmt.hu/api/publication/30742592}, author = {Czigle, Szilvia and Héthelyi B, Éva and Háznagyné Radnai, Erzsébet and Máthé, Imre and Tóth, Jaroslav}, doi = {10.1177/1934578X19857900}, journal-iso = {NAT PROD COMMUN}, journal = {NATURAL PRODUCT COMMUNICATIONS}, volume = {14}, unique-id = {30742592}, issn = {1934-578X}, year = {2019}, eissn = {1555-9475}, pages = {1-8}, orcid-numbers = {Háznagyné Radnai, Erzsébet/0000-0003-4034-5989} } @article{MTMT:3319150, title = {Planar chromatography in the quality control of adulterated Citrus paradisi seed extract-containing products}, url = {https://m2.mtmt.hu/api/publication/3319150}, author = {Csupor, Dezső and Micsinay, Ákos and Máthé, Imre and Horváth-Boros, Klára and Kiss, Tivadar and Hohmann, Judit}, doi = {10.1556/1006.2018.31.1.3}, journal-iso = {J PLANAR CHROMATOGR MOD TLC}, journal = {JPC - JOURNAL OF PLANAR CHROMATOGRAPHY - MODERN TLC}, volume = {31}, unique-id = {3319150}, issn = {0933-4173}, abstract = {Grapefruit (Citrus paradisi) seeds are increasingly applied for medicinal purposes, especially due to their antimicrobial and immunostimulant features, to treat or prevent common cold. However, the scientific background of these uses has not been established. To date, only in vitro studies support the antimicrobial effect of the seeds, and there are no data on the systemic antibiotic or other clinical effects. Moreover, recent data refer to the adulteration of grapefruit seed products with synthetic antiseptics which may be an explanation for the antimicrobial efficacy of some formulations. The aim of our study was to develop a simple thin-layer chromatography- based method for the quality control of grapefruit seed extracts. Besides the analytical procedure, we report a quick and simple method for the isolation of limonoids from grapefruit seeds. Limonoids are characteristic compounds of the seeds; hence, the detection of these marker compounds may be the basis of grapefruit identification. Further, a thin-layer chromatographic screening for synthetic antiseptics (quaternary ammonium salts) is also part of the quality control procedure.}, year = {2018}, eissn = {1789-0993}, pages = {23-27}, orcid-numbers = {Csupor, Dezső/0000-0002-4088-3333; Kiss, Tivadar/0000-0003-3538-377X; Hohmann, Judit/0000-0002-2887-6392} } @{MTMT:3012237, title = {Chemical Diversity of Medicinal Plants}, url = {https://m2.mtmt.hu/api/publication/3012237}, author = {Máthé, Imre}, booktitle = {Medicinal and Aromatic Plants of the World 1.}, doi = {10.1007/978-94-017-9810-5_3}, unique-id = {3012237}, year = {2015}, pages = {35-60} } @article{MTMT:2977485, title = {Chemical constituents of Artemisia asiatica roots}, url = {https://m2.mtmt.hu/api/publication/2977485}, author = {Hajdú, Zsuzsanna and Zana, Ágnes and Jedlinszki, Nikoletta and Máthé, Imre and Dombi, G and Hohmann, Judit}, doi = {10.1055/s-0035-1565429}, journal-iso = {PLANTA MED}, journal = {PLANTA MEDICA: NATURAL PRODUCTS AND MEDICINAL PLANT RESEARCH}, volume = {81}, unique-id = {2977485}, issn = {0032-0943}, year = {2015}, eissn = {1439-0221}, orcid-numbers = {Zana, Ágnes/0000-0001-8569-1776; Jedlinszki, Nikoletta/0000-0001-5070-9809; Hohmann, Judit/0000-0002-2887-6392} } @article{MTMT:2977483, title = {Annual variation of the essential oil production of Artemisia asiatica}, url = {https://m2.mtmt.hu/api/publication/2977483}, author = {Engel, Rita and Veres, Katalin and Hajdú, Zsuzsanna and Szabó, K and Blunden, G and Hohmann, Judit and Máthé, Imre}, doi = {10.1055/s-0035-1565844}, journal-iso = {PLANTA MED}, journal = {PLANTA MEDICA: NATURAL PRODUCTS AND MEDICINAL PLANT RESEARCH}, volume = {81}, unique-id = {2977483}, issn = {0032-0943}, year = {2015}, eissn = {1439-0221}, orcid-numbers = {Veres, Katalin/0000-0001-7108-3622; Hohmann, Judit/0000-0002-2887-6392} } @article{MTMT:2904138, title = {Isolation and structural determination of new metabolites from Artemisia asiatica roots}, url = {https://m2.mtmt.hu/api/publication/2904138}, author = {Zana, Annamária and Hajdú, Zsuzsanna and Jedlinszki, Nikoletta and Máthé, Imre and Dombi, György and Hohmann, Judit}, doi = {10.1016/j.tet.2015.05.033}, journal-iso = {TETRAHEDRON}, journal = {TETRAHEDRON}, volume = {71}, unique-id = {2904138}, issn = {0040-4020}, abstract = {Abstract Two new 2,2-dimethyl-chromene derivatives and the new pentaisovaleryl sucrose were isolated from the roots of Artemisia asiatica together with the known 1-(5-acetyl-2,4-dihydroxy-phenyl)-3-methyl-butan-1-one, 6-hydroxytremetone and (E)-coniferyl aldehyde. The structures of the compounds were elucidated by extensive 1D (1H, 13C and JMOD) and 2D (1H–1H COSY, HSQC, HMBC and NOESY) NMR studies and APCIMS and HRESIMS investigations. 6-Acetyl-3,7-dihydroxy-2,2-dimethyl-chromene and 6-acetyl-3-hydroxy-2,2-dimethyl-chromene are biogenetically related to 1-(5-acetyl-2,4-dihydroxy-phenyl)-3-methyl-butan-1-one and 6-hydroxytremetone as all having isoprenoid acetophenone origin. All the isolated compounds were described for the first time from this species; interestingly none of them are related to the metabolites identified from the extracts of the aerial part of the plant.}, keywords = {ASTERACEAE; Acetophenone; Artemisia asiatica; Sucrose polyester; Chromene}, year = {2015}, eissn = {1464-5416}, pages = {4817-4820}, orcid-numbers = {Jedlinszki, Nikoletta/0000-0001-5070-9809; Hohmann, Judit/0000-0002-2887-6392} } @article{MTMT:2781164, title = {Topical analgesic, anti-inflammatory and antioxidant properties of Oxybaphus nyctagineus: Phytochemical characterization of active fractions}, url = {https://m2.mtmt.hu/api/publication/2781164}, author = {Könczöl, Árpád and Engel, Rita and Szabó, K and Hornok, K and Tóth, S and Béni, Zoltán and Prechl, A and Máthé, Imre and Balogh, György Tibor}, doi = {10.1016/j.jep.2014.06.020}, journal-iso = {J ETHNOPHARMACOL}, journal = {JOURNAL OF ETHNOPHARMACOLOGY}, volume = {155}, unique-id = {2781164}, issn = {0378-8741}, abstract = {Ethnopharmacological relevance Oxybaphus nyctagineus (Michx.) Sweet has traditionally been used by several Native American tribes predominantly as a topical anti-inflammatory and analgesic agent. Aim of the study To evaluate the antioxidant, analgesic and anti-inflammatory activity of the extracts prepared from the aerial parts of Oxybaphus nyctagineus and to characterize the major chemical constituents of the bioactive extracts. Materials and methods Crude polar and apolar extracts (PCE and ACE) of the herb of Oxybaphus nyctagineus were prepared and tested in the models of the CFA-induced hyperalgesia in rat knee and carrageenan-induced paw edema in rat. To identify the active compounds, subfractions were prepared by column chromatography and subjected in vitro assays, such as antioxidant assays (DPPH, peroxynitrite (ONOO-) scavenging), and the LPS-induced IL-1β release test in human monocytes. Preparative HPLC was employed for the isolation of active substances, while phytochemical analysis was performed by mean of LC-MS/MS and NMR. Results The topically administered PCE and ACE of Oxybaphus nyctagineus demonstrated a significant analgesic and anti-inflammatory effect in the inflammation animal models. The subfraction A4 of ACE and the subfraction P5 of PCE considerably inhibited the LPS-induced IL-1β release in human monocytes, while the strongest activity was localized in the subfraction P5 in the antioxidant assays. The HPLC-MS/MS and NMR analysis revealed that 6-methoxyflavonol diglycosides, namely patuletin-3-O-robinobioside (1), 6-methoxykaempferol-3-O- robinobioside (2), spinacetin-3-O-robinobioside (3), and hydroxy-polyenoic fatty acids, namely corchorifatty acid B (4), 9-hydroxy-10E,12Z,15Z-octadecatrienoic acid (9-HOT acid) (5), and 9-hydroxy-10E,12Z-octadecadienoic acid (9-HOD acid) (6) were present in PCE, and in ACE as major compounds. Conclusion The results of this study established a pharmacological evidence for the traditional use of Oxybaphus nyctagineus as an anti-inflammatory agent used topically, and provided data on its phytochemical composition for the first time. © 2014 Elsevier Ireland Ltd. All rights reserved.}, keywords = {analgesic activity; anti-inflammatory activity; Oxybaphus nyctagineus; Hydroxy-polyenoic fatty acids; 6-methoxyflavonol diglycosides}, year = {2014}, eissn = {1872-7573}, pages = {776-784}, orcid-numbers = {Béni, Zoltán/0000-0002-1275-4155; Balogh, György Tibor/0000-0003-3347-1880} } @article{MTMT:2768295, title = {Antiproliferative activity of Artemisia asiatica cultivated in Central Europe}, url = {https://m2.mtmt.hu/api/publication/2768295}, author = {Hajdú, Zsuzsanna and Hohmann, Judit and Forgó, Péter and Máthé, Imre and Molnár, J and Zupkó, István}, doi = {10.1055/s-0034-1394907}, journal-iso = {PLANTA MED}, journal = {PLANTA MEDICA: NATURAL PRODUCTS AND MEDICINAL PLANT RESEARCH}, volume = {80}, unique-id = {2768295}, issn = {0032-0943}, year = {2014}, eissn = {1439-0221}, pages = {1492-1492}, orcid-numbers = {Hohmann, Judit/0000-0002-2887-6392; Forgó, Péter/0000-0002-0279-6896; Zupkó, István/0000-0003-3243-5300} } @article{MTMT:2753693, title = {Antiproliferative Activity of Artemisia asiatica Extract and Its Constituents on Human Tumor Cell Lines}, url = {https://m2.mtmt.hu/api/publication/2753693}, author = {Hajdú, Zsuzsanna and Hohmann, Judit and Forgó, Péter and Máthé, Imre and Molnár, Judit and Zupkó, István}, doi = {10.1055/s-0034-1383146}, journal-iso = {PLANTA MED}, journal = {PLANTA MEDICA: NATURAL PRODUCTS AND MEDICINAL PLANT RESEARCH}, volume = {80}, unique-id = {2753693}, issn = {0032-0943}, year = {2014}, eissn = {1439-0221}, pages = {1692-1697}, orcid-numbers = {Hohmann, Judit/0000-0002-2887-6392; Forgó, Péter/0000-0002-0279-6896; Zupkó, István/0000-0003-3243-5300} }