TY - JOUR AU - Kunfi, Attila AU - Jablonkai, István AU - Gazdag, Tamás AU - Mayer, Péter József AU - Kalapos, Péter Pál AU - Németh, Krisztina AU - Holczbauer, Tamás AU - London, Gábor TI - A photoresponsive palladium complex of an azopyridyl-triazole ligand: light-controlled solubility drives catalytic activity in the Suzuki coupling reaction JF - RSC ADVANCES J2 - RSC ADV VL - 11 PY - 2021 IS - 38 SP - 23419 EP - 23429 PG - 11 SN - 2046-2069 DO - 10.1039/D1RA03838A UR - https://m2.mtmt.hu/api/publication/32104244 ID - 32104244 LA - English DB - MTMT ER - TY - CHAP AU - Jablonkai, István AU - Kunfi, Attila AU - Qu, Da-Hui AU - London, Gábor ED - Török, Béla ED - Schafer, C TI - A new color in green chemistry: Photochromic molecular switches as components of multifunctional catalytic systems T2 - Non-Traditional Activation Methods in Green and Sustainable Applications PB - Elsevier Inc. CY - Amsterdam SN - 9780128190159 PY - 2021 SP - 241 EP - 282 PG - 42 DO - 10.1016/B978-0-12-819009-8.00006-2 UR - https://m2.mtmt.hu/api/publication/31899670 ID - 31899670 LA - English DB - MTMT ER - TY - JOUR AU - Kardos, Julianna AU - Héja, László AU - Simon, Ágnes AU - Jablonkai, István AU - Kovacs, Richard AU - Jemnitz, Katalin TI - Copper signalling: causes and consequences (vol 16, 71 , 2018) JF - CELL COMMUNICATION AND SIGNALING J2 - CELL COMM SIGN VL - 16 PY - 2018 PG - 3 SN - 1478-811X DO - 10.1186/s12964-018-0292-4 UR - https://m2.mtmt.hu/api/publication/30379283 ID - 30379283 AB - Following publication of the original article [1], the authors reported an error in Table 3. The correct version of Table 3 is shown below:The publishers apologise for this error. The original article [1] has been corrected. LA - English DB - MTMT ER - TY - JOUR AU - Kardos, Julianna AU - Héja, László AU - Simon, Ágnes AU - Jablonkai, István AU - Kovács, Richárd AU - Jemnitz, Katalin TI - Copper signalling: causes and consequences JF - CELL COMMUNICATION AND SIGNALING J2 - CELL COMM SIGN VL - 16 PY - 2018 IS - 1 PG - 21 SN - 1478-811X DO - 10.1186/s12964-018-0277-3 UR - https://m2.mtmt.hu/api/publication/30317831 ID - 30317831 N1 - Journal Article; Review Funding Agency and Grant Number: [KMR_12-1-2012-0112 TRANSRAT]; [VEKOP-2.1.1-15-2016-00156]; [OTKA K124558] Funding text: This work was supported by grants KMR_12-1-2012-0112 TRANSRAT, VEKOP-2.1.1-15-2016-00156 and OTKA K124558. Functional Pharmacology Research Group, Institute of Organic Chemistry, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar Tudósok körútja 2, Budapest, 1117, Hungary Institute of Neurophysiology, Charité-Universitätsmedizin, Berlin, Germany Cited By :28 Export Date: 6 April 2021 Correspondence Address: Kardos, J.; Functional Pharmacology Research Group, Magyar Tudósok körútja 2, Hungary; email: kardos.julianna@ttk.mta.hu Functional Pharmacology Research Group, Institute of Organic Chemistry, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar Tudósok körútja 2, Budapest, 1117, Hungary Institute of Neurophysiology, Charité-Universitätsmedizin, Berlin, Germany Cited By :28 Export Date: 7 April 2021 Correspondence Address: Kardos, J.; Functional Pharmacology Research Group, Magyar Tudósok körútja 2, Hungary; email: kardos.julianna@ttk.mta.hu Functional Pharmacology Research Group, Institute of Organic Chemistry, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar Tudósok körútja 2, Budapest, 1117, Hungary Institute of Neurophysiology, Charité-Universitätsmedizin, Berlin, Germany Cited By :37 Export Date: 29 July 2021 Correspondence Address: Kardos, J.; Functional Pharmacology Research Group, Magyar Tudósok körútja 2, Hungary; email: kardos.julianna@ttk.mta.hu Chemicals/CAS: 4 aminobutyric acid, 28805-76-7, 56-12-2; captopril, 62571-86-2; clioquinol, 130-26-7, 8057-20-3; copper, 15158-11-9, 7440-50-8; disulfiram, 97-77-8; elesclomol, 488832-69-5; glutathione, 70-18-8; metformin, 1115-70-4, 657-24-9; penicillamine, 2219-30-9, 52-67-5; tetrathiomolybdic acid, 13718-35-9, 16330-92-0; trientine, 112-24-3, 38260-01-4; Copper Funding details: Hungarian Scientific Research Fund, OTKA, K124558 Funding text 1: This work was supported by grants KMR_12-1-2012-0112 TRANSRAT, VEKOP-2.1.1-15-2016-00156 and OTKA K124558. AB - Copper-containing enzymes perform fundamental functions by activating dioxygen (O-2) and therefore allowing chemical energy-transfer for aerobic metabolism. The copper-dependence of O-2 transport, metabolism and production of signalling molecules are supported by molecular systems that regulate and preserve tightly-bound static and weakly-bound dynamic cellular copper pools. Disruption of the reducing intracellular environment, characterized by glutathione shortage and ambient Cu(II) abundance drives oxidative stress and interferes with the bidirectional, copper-dependent communication between neurons and astrocytes, eventually leading to various brain disease forms. A deeper understanding of of the regulatory effects of copper on neuro-glia coupling via polyamine metabolism may reveal novel copper signalling functions and new directions for therapeutic intervention in brain disorders associated with aberrant copper metabolism. LA - English DB - MTMT ER - TY - JOUR AU - Miskolczy, Zsombor AU - Biczók, László AU - Jablonkai, István TI - Kinetics of the reversible inclusion of flavopereirine in cucurbit[7]uril JF - PHYSICAL CHEMISTRY CHEMICAL PHYSICS J2 - PHYS CHEM CHEM PHYS VL - 19 PY - 2017 IS - 1 SP - 766 EP - 773 PG - 8 SN - 1463-9076 DO - 10.1039/C6CP07553C UR - https://m2.mtmt.hu/api/publication/3149898 ID - 3149898 LA - English DB - MTMT ER - TY - JOUR AU - Jemnitz, Katalin AU - Batai-Konczos, A AU - Szabó, Mónika AU - Ioja, Enikő AU - Kolacsek, Orsolya AU - Orbán, Tamás I. AU - Török, György AU - Homolya, László AU - Kovacs, E AU - Jablonkai, István AU - Veres, Zsuzsa TI - A transgenic rat hepatocyte - Kupffer cell co-culture model for evaluation of direct and macrophage-related effect of poly(amidoamine) dendrimers JF - TOXICOLOGY IN VITRO J2 - TOXICOL IN VITRO VL - 38 PY - 2017 SP - 159 EP - 169 PG - 11 SN - 0887-2333 DO - 10.1016/j.tiv.2016.09.016 UR - https://m2.mtmt.hu/api/publication/3148042 ID - 3148042 AB - Increasing number of papers demonstrate that Kupffer cells (KCs) play a role in the development of drug induced liver injury (DILI). Furthermore, elevated intracellular Ca2+ level of hepatocytes is considered as a common marker of DILI. Here we applied an in vitro model based on hepatocyte mono- and hepatocyte/KC co-cultures (H/KC) isolated from transgenic rats stably expressing the GCaMP2 fluorescent Ca2+ sensor protein to investigate the effects of polycationic (G5), polyanionic (G4.5) and polyethylene-glycol coated neutral (G5 Peg) dendrimers known to accumulate in the liver, primarily in KCs. Following dendrimer exposure, hepatocyte homeostasis was measured by MTT cytotoxicity assay and by Ca2+ imaging, while hepatocyte functions were studied by CYP2B1/2 inducibility, and bilirubin and taurocholate transport. G5 was significantly more cytotoxic than G4.5 for hepatocytes and induced Ca2+ oscillation and sustained Ca2+ signals at 1muM and10 muM, respectively both in hepatocytes and KCs. Dendrimer-induced Ca2+ signals in hepatocytes were attenuated by macrophages. Activation of KCs by lipopolysaccharide and G5 decreased the inducibility of CYP2B1/2, which was restored by depleting the KCs with gadolinium-chloride and pentoxyphylline, suggesting a role of macrophages in the hindrance of CYP2B1/2 induction by G5 and lipopolysaccharide. In the H/KC, but not in the hepatocyte mono-culture, G5 reduced the canalicular efflux of bilirubin and stimulated the uptake and canalicular efflux of taurocholate. In conclusion, H/KC provides a good model for the prediction of hepatotoxic potential of drugs, especially of nanomaterials known to be trapped by macrophages, activation of which presumably contributes to DILI. LA - English DB - MTMT ER - TY - JOUR AU - Miskolczy, Zsombor AU - Biczók, László AU - Jablonkai, István TI - Multiple inclusion complex formation of protonated ellipticine with cucurbit[8]uril: thermodynamics and fluorescence properties JF - SUPRAMOLECULAR CHEMISTRY J2 - SUPRAMOL CHEM VL - 28 PY - 2016 IS - 9-10 SP - 842 EP - 848 PG - 7 SN - 1061-0278 DO - 10.1080/10610278.2016.1174237 UR - https://m2.mtmt.hu/api/publication/3068584 ID - 3068584 AB - The encapsulation of protonated ellipticine (EH+) in the cavity of cucurbit[8]uril (CB8) was studied in water at pH 4 with spectrophotometric, fluorescence spectroscopic and isothermal calorimetric measurements. The formation of three types of inclusion complexes was observed depending on the host and guest concentrations. Not only one, but also two EH+ was capable of encapsulation in CB8 in 37 μM EH+ solution and the thermodynamics of the binding steps were revealed. The produced very stable complexes showed markedly different absorption and fluorescence properties. When large excess of CB8 was employed in dilute (0.49 μM) EH+ solution, sequential binding of two CB8 occurred to the monomer alkaloid bringing about a substantial alteration in the fluorescence decay kinetics. The driving force of the 1:2 guest:host complex formation was much lower than that of 1:1 encapsulation. © 2016 Informa UK Limited, trading as Taylor & Francis Group LA - English DB - MTMT ER - TY - JOUR AU - Miskolczy, Zsombor AU - Biczók, László AU - Jablonkai, István TI - The origin of the dual fluorescence of protonated ellipticine in water JF - CHEMICAL PHYSICS LETTERS J2 - CHEM PHYS LETT VL - 644 PY - 2016 SP - 292 EP - 295 PG - 4 SN - 0009-2614 DO - 10.1016/j.cplett.2015.12.013 UR - https://m2.mtmt.hu/api/publication/2989580 ID - 2989580 LA - English DB - MTMT ER - TY - CHAP AU - Jablonkai, István ED - Andrew, Price ED - Jessica, Kelton ED - Lina, Sarunaite TI - Herbicide Metabolism in Weeds. Selectivity and Herbicide Resistance TS - Selectivity and Herbicide Resistance T2 - Herbicides, Physiology of Action, and Safety PB - IntechOpen CY - Rijeka SN - 9789535122173 PY - 2015 SP - 223 EP - 251 PG - 29 UR - https://m2.mtmt.hu/api/publication/2983851 ID - 2983851 LA - English DB - MTMT ER - TY - JOUR AU - Kardos, Julianna AU - Jemnitz, Katalin AU - Jablonkai, István AU - Bóta, Attila AU - Varga, Zoltán AU - Benéné Visy, Júlia AU - Héja, László TI - The Janus facet of nanomaterials JF - BIOMED RESEARCH INTERNATIONAL J2 - BIOMED RES INT VL - 2015 PY - 2015 PG - 10 SN - 2314-6133 DO - 10.1155/2015/317184 UR - https://m2.mtmt.hu/api/publication/2826747 ID - 2826747 N1 - Megjegyzés-24992972 N1 Funding Details: 102166, OTKA, Országos Tudományos Kutatási Alapprogramok Megjegyzés-24993007 N1 Funding Details: 102166, OTKA, Országos Tudományos Kutatási Alapprogramok Group of Functional Pharmacology, Institute of Cognitive Neuroscience and Psychology, Hungarian Academy of Sciences, Magyar Tudósok körútja 2, Budapest, 1117, Hungary Group of Biological Nanochemistry, Institute of Materials and Environmental Chemistry, Hungarian Academy of Sciences, Budapest, 1117, Hungary Group of Chemical Biology, Institute of Organic Chemistry, Hungarian Academy of Sciences, Budapest, 1117, Hungary Cited By :6 Export Date: 7 April 2021 Correspondence Address: Kardos, J.; Group of Functional Pharmacology, Magyar Tudósok körútja 2, Hungary LA - English DB - MTMT ER -